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GENE - TERM ANNOTATION REPORT

3 Annotations Found.

An association has been curated linking Nox4 and hypertension in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Saha S, etal., Can J Physiol Pharmacol. 2008 Apr;86(4):190-8.
  • The annotation has been inferred from sequence orthology with Nox4 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 3 additional annotations were made from Saha S, etal., Can J Physiol Pharmacol. 2008 Apr;86(4):190-8.
  • 961 RGD objects have been annotated to hypertension  (DOID:10763)
  • 19 papers in RGD have been used to annotate Nox4
  • Curation Notes: protein:increased expression:aorta, vascular associated smooth muscle cell


    • An association has been curated linking Nox4 and hypertension in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Cowley AW Jr, etal., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7.
  • The annotation has been inferred from sequence orthology with Nox4 (Rattus norvegicus) [(IMP) inferred from mutant phenotype]
  • 21 additional annotations were made from Cowley AW Jr, etal., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7.
  • 961 RGD objects have been annotated to hypertension  (DOID:10763)
  • 19 papers in RGD have been used to annotate Nox4


    • An association has been curated linking Nox4 and hypertension in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with NOX4 (Homo sapiens) [(EXP) inferred from experiment]
  • 961 RGD objects have been annotated to hypertension  (DOID:10763)
  • 19 papers in RGD have been used to annotate Nox4
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:27659729 PMID:27847271 PMID:32147540


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