Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - TERM ANNOTATION REPORT

2 Annotations Found.

An association has been curated linking MAPK1 and Alzheimer's disease in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Guo C, etal., Neuropsychopharmacology. 2017 Dec;42(13):2504-2515. doi: 10.1038/npp.2017.8. Epub 2017 Jan 12.
  • The annotation has been inferred from sequence orthology with Mapk1 (Mus musculus) [(IDA) inferred from direct assay]
  • 5 additional annotations were made from Guo C, etal., Neuropsychopharmacology. 2017 Dec;42(13):2504-2515. doi: 10.1038/npp.2017.8. Epub 2017 Jan 12.
  • 547 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 86 papers in RGD have been used to annotate MAPK1
  • Qualifier: treatment


    • An association has been curated linking MAPK1 and Alzheimer's disease in Homo sapiens.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Gerschütz A, etal., J Alzheimers Dis. 2014;40(1):135-42. doi: 10.3233/JAD-131280.
  • 2 additional annotations were made from Gerschütz A, etal., J Alzheimers Dis. 2014;40(1):135-42. doi: 10.3233/JAD-131280.
  • 547 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 86 papers in RGD have been used to annotate MAPK1
  • Qualifier: onset
  • Curation Notes: mRNA:increased expression: CA2 field of hippocampus, pyramidal neuron


    • Go Back to source page   Continue to Ontology report