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GENE - TERM ANNOTATION REPORT

7 Annotations Found.

An association has been curated linking Igf1 and Alzheimer's disease in Mus musculus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Hu YK, etal., Neurosci Bull. 2013 Dec;29(6):745-51. doi: 10.1007/s12264-013-1348-5. Epub 2013 Jun 5.
  • 2 additional annotations were made from Hu YK, etal., Neurosci Bull. 2013 Dec;29(6):745-51. doi: 10.1007/s12264-013-1348-5. Epub 2013 Jun 5.
  • 496 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 170 papers in RGD have been used to annotate Igf1
  • Curation Notes: protein:decreased expression:hippocampus:


    • An association has been curated linking Igf1 and Alzheimer's disease in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Wang W, etal., Neurosci Lett. 2012 Nov 30;531(1):20-3. doi: 10.1016/j.neulet.2012.10.015. Epub 2012 Oct 23.
  • The annotation has been inferred from sequence orthology with IGF1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Wang W, etal., Neurosci Lett. 2012 Nov 30;531(1):20-3. doi: 10.1016/j.neulet.2012.10.015. Epub 2012 Oct 23.
  • 496 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 170 papers in RGD have been used to annotate Igf1
  • Qualifier: susceptibility
  • Curation Notes: DNA:polymorphism:intron: rs972936(human)


    • An association has been curated linking Igf1 and Alzheimer's disease in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Asthana S, etal., Psychoneuroendocrinology. 1999 Aug;24(6):657-77.
  • The annotation has been inferred from sequence orthology with IGF1 (Homo sapiens) [(IDA) inferred from direct assay]
  • 5 additional annotations were made from Asthana S, etal., Psychoneuroendocrinology. 1999 Aug;24(6):657-77.
  • 496 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 170 papers in RGD have been used to annotate Igf1
  • Qualifier: treatment


    • An association has been curated linking Igf1 and Alzheimer's disease in Mus musculus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Trueba-Saiz A, etal., Transl Psychiatry. 2013 Dec 3;3:e330. doi: 10.1038/tp.2013.102.
  • 5 additional annotations were made from Trueba-Saiz A, etal., Transl Psychiatry. 2013 Dec 3;3:e330. doi: 10.1038/tp.2013.102.
  • 496 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 170 papers in RGD have been used to annotate Igf1
  • Qualifier: onset
  • Curation Notes: protein:altered expression:plasma,cerebral spinal fluid:


    • An association has been curated linking Igf1 and Alzheimer's disease in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Trueba-Saiz A, etal., Transl Psychiatry. 2013 Dec 3;3:e330. doi: 10.1038/tp.2013.102.
  • The annotation has been inferred from sequence orthology with IGF1 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Trueba-Saiz A, etal., Transl Psychiatry. 2013 Dec 3;3:e330. doi: 10.1038/tp.2013.102.
  • 496 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 170 papers in RGD have been used to annotate Igf1
  • Curation Notes: protein:altered expression:plasma,cerebral spinal fluid:


    • An association has been curated linking Igf1 and Alzheimer's disease in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from van Exel E, etal., Neurobiol Aging. 2014 Mar;35(3):725.e7-10. doi: 10.1016/j.neurobiolaging.2013.08.014. Epub 2013 Sep 20.
  • The annotation has been inferred from sequence orthology with IGF1 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from van Exel E, etal., Neurobiol Aging. 2014 Mar;35(3):725.e7-10. doi: 10.1016/j.neurobiolaging.2013.08.014. Epub 2013 Sep 20.
  • 496 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 170 papers in RGD have been used to annotate Igf1
  • Qualifier: onset
  • Curation Notes: protein:increased expression:serum:


    • An association has been curated linking Igf1 and Alzheimer's disease in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with IGF1 (Homo sapiens) [(EXP) inferred from experiment]
  • 496 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 170 papers in RGD have been used to annotate Igf1
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:15750215


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