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GENE - TERM ANNOTATION REPORT

15 Annotations Found.

An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Chen R, etal., J Allergy Clin Immunol. 2020 May 11. pii: S0091-6749(20)30638-2. doi: 10.1016/j.jaci.2020.05.003.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Chen R, etal., J Allergy Clin Immunol. 2020 May 11. pii: S0091-6749(20)30638-2. doi: 10.1016/j.jaci.2020.05.003.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: disease_progression


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Li S, etal., JCI Insight. 2020 May 19. pii: 138070. doi: 10.1172/jci.insight.138070.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 30 additional annotations were made from Li S, etal., JCI Insight. 2020 May 19. pii: 138070. doi: 10.1172/jci.insight.138070.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: severity
  • Curation Notes: protein:increased expression:serum (human)


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Ruan Q, etal., Intensive Care Med. 2020 May;46(5):846-848. doi: 10.1007/s00134-020-05991-x. Epub 2020 Mar 3.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 8 additional annotations were made from Ruan Q, etal., Intensive Care Med. 2020 May;46(5):846-848. doi: 10.1007/s00134-020-05991-x. Epub 2020 Mar 3.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: severity
  • Curation Notes: protein:increased expression:serum (human)


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Yuan J, etal., Inflamm Res. 2020 Jun;69(6):599-606. doi: 10.1007/s00011-020-01342-0. Epub 2020 Mar 29.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Yuan J, etal., Inflamm Res. 2020 Jun;69(6):599-606. doi: 10.1007/s00011-020-01342-0. Epub 2020 Mar 29.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: severity
  • Curation Notes: protein:increased expression:serum (human)


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Yan Y, etal., BMJ Open Diabetes Res Care. 2020 Apr;8(1). pii: 8/1/e001343. doi: 10.1136/bmjdrc-2020-001343.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 18 additional annotations were made from Yan Y, etal., BMJ Open Diabetes Res Care. 2020 Apr;8(1). pii: 8/1/e001343. doi: 10.1136/bmjdrc-2020-001343.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: disease_progression
  • Curation Notes: associated with diabetes mellitus


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Blanco-Melo D, etal., Cell. 2020 May 28;181(5):1036-1045.e9. doi: 10.1016/j.cell.2020.04.026. Epub 2020 May 15.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 20 additional annotations were made from Blanco-Melo D, etal., Cell. 2020 May 28;181(5):1036-1045.e9. doi: 10.1016/j.cell.2020.04.026. Epub 2020 May 15.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Curation Notes: protein:increased expression:serum:


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Huang C, etal., Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 63 additional annotations were made from Huang C, etal., Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: severity
  • Curation Notes: protein:increased expression:plasma (human)


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(EXP) inferred from experiment]
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:32026671 PMID:32161940 PMID:32171193 PMID:32534021


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Fraser DD, etal., Crit Care Explor. 2020 Jun 22;2(6):e0144. doi: 10.1097/CCE.0000000000000144. eCollection 2020 Jun.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 58 additional annotations were made from Fraser DD, etal., Crit Care Explor. 2020 Jun 22;2(6):e0144. doi: 10.1097/CCE.0000000000000144. eCollection 2020 Jun.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Curation Notes: protein:increased expression:plasma (human)


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Li M, etal., Nutr Metab Cardiovasc Dis. 2020 Jun 25;30(7):1061-1067. doi: 10.1016/j.numecd.2020.04.013. Epub 2020 Apr 18.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 11 additional annotations were made from Li M, etal., Nutr Metab Cardiovasc Dis. 2020 Jun 25;30(7):1061-1067. doi: 10.1016/j.numecd.2020.04.013. Epub 2020 Apr 18.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: severity
  • Curation Notes: associated with cardiovascular system disease;protein:increased expression:blood (human)


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Gao Y, etal., J Med Virol. 2020 Jul;92(7):791-796. doi: 10.1002/jmv.25770. Epub 2020 Apr 10.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Gao Y, etal., J Med Virol. 2020 Jul;92(7):791-796. doi: 10.1002/jmv.25770. Epub 2020 Apr 10.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: severity
  • Curation Notes: protein:increased expression:blood (human)


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Hou H, etal., Clin Exp Immunol. 2020 Jul;201(1):76-84. doi: 10.1111/cei.13450. Epub 2020 May 15.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 23 additional annotations were made from Hou H, etal., Clin Exp Immunol. 2020 Jul;201(1):76-84. doi: 10.1111/cei.13450. Epub 2020 May 15.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: severity
  • Curation Notes: protein:increased expression:serum (human)


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Liu Y, etal., Viral Immunol. 2020 Apr 10. doi: 10.1089/vim.2020.0062.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 15 additional annotations were made from Liu Y, etal., Viral Immunol. 2020 Apr 10. doi: 10.1089/vim.2020.0062.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: severity
  • Curation Notes: protein:increased expression:serum (human)


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Zhang X, etal., Nature. 2020 May 20. pii: 10.1038/s41586-020-2355-0. doi: 10.1038/s41586-020-2355-0.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 9 additional annotations were made from Zhang X, etal., Nature. 2020 May 20. pii: 10.1038/s41586-020-2355-0. doi: 10.1038/s41586-020-2355-0.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: severity
  • Curation Notes: protein:increased expression:serum (human)


    • An association has been curated linking Il6 and COVID-19 in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Chen L, etal., Zhonghua Jie He He Hu Xi Za Zhi. 2020 Mar 12;43(3):203-208. doi: 10.3760/cma.j.issn.1001-0939.2020.03.013.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Chen L, etal., Zhonghua Jie He He Hu Xi Za Zhi. 2020 Mar 12;43(3):203-208. doi: 10.3760/cma.j.issn.1001-0939.2020.03.013.
  • 966 RGD objects have been annotated to COVID-19  (DOID:0080600)
  • 339 papers in RGD have been used to annotate Il6
  • Qualifier: severity
  • Curation Notes: protein:increased expression:serum (human)


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