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GENE - TERM ANNOTATION REPORT

3 Annotations Found.

An association has been curated linking Xpo1 and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from direct assay (IDA)
    		•  
  • The annotation was made from Ortega JF, etal., Oncotarget. 2016 Apr 26;7(17):24339-47. doi: 10.18632/oncotarget.8248.
  • 7 additional annotations were made from Ortega JF, etal., Oncotarget. 2016 Apr 26;7(17):24339-47. doi: 10.18632/oncotarget.8248.
  • 948 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 35 papers in RGD have been used to annotate Xpo1
  • Qualifier: treatment


    • An association has been curated linking Xpo1 and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Chen L, etal., Biosci Rep. 2019 Aug 19;39(8). pii: BSR20190827. doi: 10.1042/BSR20190827. Print 2019 Aug 30.
  • The annotation has been inferred from sequence orthology with XPO1 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Chen L, etal., Biosci Rep. 2019 Aug 19;39(8). pii: BSR20190827. doi: 10.1042/BSR20190827. Print 2019 Aug 30.
  • 948 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 35 papers in RGD have been used to annotate Xpo1
  • Qualifier: exacerbates
  • Curation Notes: mRNA:increased expression:liver (human)


    • An association has been curated linking Xpo1 and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Zheng Y, etal., Cancer Chemother Pharmacol. 2014 Sep;74(3):487-95. doi: 10.1007/s00280-014-2495-8. Epub 2014 Jul 17.
  • The annotation has been inferred from sequence orthology with XPO1 (Homo sapiens) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Zheng Y, etal., Cancer Chemother Pharmacol. 2014 Sep;74(3):487-95. doi: 10.1007/s00280-014-2495-8. Epub 2014 Jul 17.
  • 948 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 35 papers in RGD have been used to annotate Xpo1
  • Qualifier: ameliorates
  • Curation Notes: human cell line in a mouse model


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