MWF/ZtmRrrc |
renal plasma flow (PAH) |
enalapril (50 mg/l) (for 182 days) |
Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. |
kidney plasma flow trait |
male |
246 days
| 6 |
7.6 |
ml/min |
0.33 |
0.8 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
100938 |
2541 |
WKY |
renal plasma flow to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
kidney plasma flow trait |
male |
0 days
| 8 |
2.32 |
ml/min/100g |
0.11 |
0.31 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
unx |
28 |
days |
|
99953 |
2378 |
MWF/ZtmRrrc |
renal filtration fraction |
enalapril (50 mg/l) (for 182 days) |
Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. |
glomerular filtration trait |
male |
246 days
| 6 |
0.3 |
null |
0.02 |
0.04 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
100946 |
2541 |
MWF/ZtmRrrc |
renal filtration fraction |
enalapril (50 mg/l) (for 60 days) |
Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. |
glomerular filtration trait |
male |
126 days
| 8 |
0.21 |
null |
0.02 |
0.06 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
100944 |
2541 |
WKY |
renal vascular resistance |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
arterial blood pressure trait |
male |
0 days
| 8 |
9.2 |
mmHg/ml/min |
0.4 |
1.13 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
unx |
28 |
days |
|
99963 |
2378 |
MWF/ZtmRrrc |
renal plasma flow (PAH) |
enalapril (50 mg/l) (for 60 days) |
Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. |
kidney plasma flow trait |
male |
126 days
| 8 |
10.6 |
ml/min |
0.57 |
1.6 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
100936 |
2541 |
MWF/ZtmRrrc |
renal plasma flow to body weight ratio |
enalapril (50 mg/l) (for 60 days) |
Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. |
kidney plasma flow trait |
male |
126 days
| 8 |
2.84 |
ml/min/100g |
0.14 |
0.39 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
100940 |
2541 |
WKY |
renal vascular resistance |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
arterial blood pressure trait |
male |
0 days
| 6 |
8.8 |
mmHg/ml/min |
0.5 |
1.22 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
unx |
28 |
days |
|
99964 |
2378 |
WKY |
renal plasma flow to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
kidney plasma flow trait |
male |
0 days
| 6 |
2.42 |
ml/min/100g |
0.09 |
0.22 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
unx |
28 |
days |
|
99954 |
2378 |
WKY |
renal vascular resistance |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
arterial blood pressure trait |
male |
0 days
| 16 |
7.1 |
mmHg/ml/min |
0.3 |
1.2 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
unx |
168 |
days |
|
99998 |
2378 |
WKY |
renal plasma flow to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
kidney plasma flow trait |
male |
0 days
| 16 |
3.19 |
ml/min/100g |
0.13 |
0.52 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
unx |
168 |
days |
|
99994 |
2378 |
MWF/ZtmRrrc |
renal plasma flow to body weight ratio |
enalapril (50 mg/l) (for 182 days) |
Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. |
kidney plasma flow trait |
male |
246 days
| 6 |
1.71 |
ml/min/100g |
0.09 |
0.23 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
100942 |
2541 |
WKY |
efferent arteriolar hydraulic pressure |
enalapril (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
blood molecular composition trait |
male |
0 days
| 8 |
24.0 |
mmHg |
0.4 |
1.13 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
PA IV 50mg/kg |
0 |
|
pt |
109969 |
2479 |
WKY |
renal plasma flow to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
kidney plasma flow trait |
male |
0 days
| 16 |
3.15 |
ml/min/100g |
0.13 |
0.52 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
unx |
168 |
days |
|
99993 |
2378 |
WKY |
renal vascular resistance |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
arterial blood pressure trait |
male |
0 days
| 16 |
6.8 |
mmHg/ml/min |
0.3 |
1.2 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
unx |
168 |
days |
|
99999 |
2378 |