DA/Bkl |
post-insult time to onset of experimental arthritis |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
joint integrity trait |
both |
66 days-126 days |
105 |
15.0 |
d |
0.2 |
2.0 |
in vivo visual assessment |
0.0 |
immunized |
10 |
days |
variable |
|
|
68143 |
850 |
BN/SsN |
percentage of study population developing chronic experimental arthritis during a period of time |
Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
joint integrity trait |
male |
66 days-126 days |
13 |
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69923 |
1241 |
BBDR/Rhw |
calculated serum anti-rat type 2 collagen autoantibody titer |
Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
blood autoantibody amount |
female |
66 days-126 days |
13 |
31.7 |
null |
1.75 |
6.3 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
titer |
|
69926 |
1241 |
DA/Bkl |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
joint integrity trait |
both |
66 days-126 days |
105 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
immunized |
10 |
days |
variable |
|
|
69959 |
850 |
DA.PVG.1AV1-(D4Rat155-Spr) |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
14 |
14.3 |
d |
0.3 |
1.12 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69780 |
1162 |
DA/Ztm |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
12 |
13.4 |
% |
1.4 |
4.85 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69798 |
1162 |
DA.PVG.1AV1-(D4Rat155-D4Rat84) |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
14 |
71.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69711 |
1162 |
DA.PVG.1AV1-(D4Rat155-Spr) |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
14 |
660.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69759 |
1162 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
male |
120 days-200 days |
13 |
15.5 |
d |
0.2 |
0.72 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69783 |
1162 |
DA.PVG.1AV1-(D4Rat63-D4Rat203) |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
10 |
16.4 |
d |
0.8 |
2.53 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69791 |
1162 |
DA.PVG.1AV1-(D4Rat63-D4Rat203) |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
10 |
14.6 |
% |
1.8 |
5.69 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69810 |
1162 |
DA.F344-(D10Rat204-D10Arb22)/Arb |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
female |
63 days-126 days |
10 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70155 |
1299 |
F344/NHsd |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
female |
63 days-126 days |
10 |
30.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70149 |
1299 |
BN/SsN |
percentage of study population developing chronic experimental arthritis during a period of time |
Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
joint integrity trait |
female |
66 days-126 days |
7 |
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69924 |
1241 |
BN/SsN |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
joint integrity trait |
both |
66 days-126 days |
13 |
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
immunized |
10 |
days |
variable |
|
|
69961 |
850 |
DA/Ztm |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
10 |
14.2 |
d |
0.4 |
1.26 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69790 |
1162 |
PVG.1AV1 |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
15 |
33.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69710 |
1162 |
DA/Ztm |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
12 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69709 |
1162 |
DA/Bkl |
body weight loss |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
body mass |
both |
66 days-126 days |
105 |
19.0 |
% |
0.49 |
5.0 |
body weighing method |
0.0 |
immunized |
10 |
days |
variable |
(weight loss) |
|
69960 |
850 |
PVG.1AV1 |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
15 |
250.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69757 |
1162 |
DA/Bkl |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
female |
63 days-126 days |
14 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70147 |
1299 |
BN/SsN |
calculated serum anti-rat type 2 collagen autoantibody titer |
Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
blood autoantibody amount |
male |
66 days-126 days |
13 |
1.3 |
null |
0.28 |
1.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
titer |
|
69927 |
1241 |
DA.PVG.1AV1-(D4Rat63-D4Rat203) |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
10 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69723 |
1162 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
11 |
540.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69760 |
1162 |
DA/Ztm |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
12 |
790.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69756 |
1162 |
DA/Ztm |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
male |
120 days-180 days |
9 |
590.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69761 |
1162 |
DA/Ztm |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
10 |
600.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69769 |
1162 |
DA.PVG.1AV1-(D4Rat63-D4Rat203) |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
10 |
660.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69770 |
1162 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
11 |
15.4 |
d |
0.5 |
1.66 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69781 |
1162 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
11 |
0.7 |
% |
1.6 |
5.31 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69801 |
1162 |
DA/Ztm |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
10 |
22.8 |
% |
1.1 |
3.48 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69809 |
1162 |
DA/Ztm |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
male |
120 days-200 days |
9 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69714 |
1162 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
male |
120 days-200 days |
13 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69715 |
1162 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
11 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69713 |
1162 |
BN/SsN |
calculated serum anti-rat type 2 collagen autoantibody titer |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
blood autoantibody amount |
both |
66 days-126 days |
13 |
2.0 |
null |
0.55 |
2.0 |
enzyme linked immunosorbent assay |
0.0 |
immunized |
10 |
days |
variable |
titer |
|
69965 |
850 |
DA.PVG.1AV1-(D4Rat155-D4Rat84) |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
14 |
17.6 |
d |
0.8 |
2.99 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69779 |
1162 |
BBDR/Rhw |
percentage of study population developing chronic experimental arthritis during a period of time |
Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
joint integrity trait |
female |
66 days-126 days |
13 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69922 |
1241 |
DA.F344-(D10Arb20-D10Arb22)/Arb |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
female |
63 days-126 days |
10 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70153 |
1299 |
DA.F344-(D10Rat204-D10Arb22)/Arb |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
male |
63 days-126 days |
9 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70154 |
1299 |
BN/SsN |
body weight loss |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
body mass |
both |
66 days-126 days |
13 |
0.0 |
% |
0.0 |
0.0 |
body weighing method |
0.0 |
immunized |
10 |
days |
variable |
(weight loss) |
|
69958 |
850 |
BN/SsN |
calculated serum anti-porcine type 2 collagen antibody titer |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
blood immunoglobulin amount |
both |
66 days-126 days |
13 |
3.0 |
null |
0.55 |
2.0 |
enzyme linked immunosorbent assay |
0.0 |
immunized |
10 |
days |
variable |
titer |
|
69964 |
850 |
DA/Bkl |
calculated serum anti-porcine type 2 collagen antibody titer |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
blood immunoglobulin amount |
both |
66 days-126 days |
105 |
19.0 |
null |
0.59 |
6.0 |
enzyme linked immunosorbent assay |
0.0 |
immunized |
10 |
days |
variable |
titer |
|
69962 |
850 |
DA/Ztm |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
10 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69722 |
1162 |
DA.PVG.1AV1-(D4Rat155-D4Rat84) |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
14 |
500.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69758 |
1162 |
DA/Bkl |
calculated serum anti-rat type 2 collagen autoantibody titer |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
blood autoantibody amount |
both |
66 days-126 days |
105 |
15.0 |
null |
0.59 |
6.0 |
enzyme linked immunosorbent assay |
0.0 |
immunized |
10 |
days |
variable |
titer |
|
69963 |
850 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
male |
120 days-180 days |
13 |
540.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69762 |
1162 |
DA/Ztm |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
male |
120 days-200 days |
9 |
7.5 |
% |
2.1 |
6.3 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69802 |
1162 |
DA/Ztm |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
male |
120 days-200 days |
9 |
15.2 |
d |
0.2 |
0.6 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69782 |
1162 |
BBDR/Rhw |
calculated serum anti-rat type 2 collagen autoantibody titer |
Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
blood autoantibody amount |
male |
66 days-126 days |
11 |
30.6 |
null |
1.51 |
5.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
titer |
|
69925 |
1241 |
DA/Bkl |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
male |
63 days-126 days |
15 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70146 |
1299 |
F344/NHsd |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
male |
63 days-126 days |
10 |
20.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70148 |
1299 |
BBDR/Rhw |
percentage of study population developing chronic experimental arthritis during a period of time |
Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
joint integrity trait |
male |
66 days-126 days |
11 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69921 |
1241 |
BN/SsN |
calculated serum anti-rat type 2 collagen autoantibody titer |
Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
blood autoantibody amount |
female |
66 days-126 days |
7 |
1.9 |
null |
0.68 |
1.8 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
titer |
|
69928 |
1241 |
DA/Ztm |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
12 |
14.5 |
d |
0.5 |
1.73 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69777 |
1162 |
PVG.1AV1 |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
15 |
14.6 |
d |
0.4 |
1.55 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69778 |
1162 |
DA.PVG.1AV1-(D4Rat155-Spr) |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
14 |
12.5 |
% |
0.9 |
3.37 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69800 |
1162 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
male |
120 days-200 days |
13 |
6.6 |
% |
1.3 |
4.69 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69803 |
1162 |
DA.PVG.1AV1-(D4Rat155-Spr) |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
14 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69712 |
1162 |
DA.PVG.1AV1-(D4Rat155-D4Rat84) |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
14 |
2.8 |
% |
1.0 |
3.74 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69799 |
1162 |
DA.F344-(D10Arb20-D10Arb22)/Arb |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
male |
63 days-126 days |
10 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70152 |
1299 |