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Strain |
Phenotype |
Conditions |
Study |
Experiment Name |
Sex |
Age |
# of Animals |
Value |
Units |
SEM |
SD |
Method |
Method Duration |
Post Insult Type |
Post Insult Time Value |
Post Insult Time Unit |
Method Notes |
Clinical Measurement Notes |
Record ID |
Study ID |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) and testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
female |
0 days
| 5 |
5.0 |
pg/ml |
0.36 |
0.81 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67456 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
liver tumorous lesion number to liver volume ratio |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
7380.0 |
/cm3 |
|
920.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
Add |
67457 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
3.9 |
cm3 x 10000 |
|
0.74 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67796 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
female |
0 days
| 5 |
0.42 |
ng/ml |
0.01 |
0.02 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67455 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
69.0 |
% |
|
9.8 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67458 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
15.33 |
% |
|
0.74 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
pcna index |
68110 |
655 |
|