FHH-Chr YBN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
82.53 |
mmHg |
5.21 |
16.49 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45517 |
461 |
FHH-Chr YBN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
43.02 |
mmHg |
4.38 |
13.15 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47924 |
461 |
FHH-Chr YBN/Mcwi |
left ventricular diastolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
11 |
|
5.89 |
mmHg |
0.11 |
0.35 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47210 |
461 |
FHH-Chr YBN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
10 |
|
17.9 |
IU/g |
2.2 |
6.96 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
45992 |
461 |
FHH-Chr YBN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
10 |
|
11.25 |
% |
2.37 |
7.49 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49409 |
461 |
FHH-Chr YBN/Mcwi |
left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
80.04 |
mmHg |
7.8 |
24.65 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49901 |
461 |
FHH-Chr YBN/Mcwi |
percent change in left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
42.52 |
% |
6.57 |
20.76 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48540 |
461 |
FHH-Chr YBN/Mcwi |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
56.54 |
% |
7.37 |
22.12 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46332 |
461 |
FHH-Chr YBN/Mcwi |
heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
|
202.79 |
beats/min |
16.98 |
53.71 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45161 |
461 |
FHH-Chr YBN/Mcwi |
arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
11 |
|
10.86 |
ml/min/g |
1.0 |
3.33 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46666 |
461 |
FHH-Chr YBN/Mcwi |
percent change in left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
84.57 |
% |
7.99 |
25.28 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48769 |
461 |
FHH-Chr YBN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
11 |
|
9.53 |
% |
2.47 |
8.18 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49711 |
461 |
FHH-Chr YBN/Mcwi |
time to peak heart contraction |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
11 |
|
1262.09 |
s |
28.21 |
93.58 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50240 |
461 |
FHH-Chr YBN/Mcwi |
heart contraction pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
11 |
|
21.91 |
mmHg |
2.06 |
6.85 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50010 |
461 |
FHH-Chr YBN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
77.05 |
mmHg |
5.18 |
16.39 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
|
46763 |
461 |
FHH-Chr YBN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
52.41 |
mmHg |
4.57 |
14.47 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47714 |
461 |
FHH-Chr YBN/Mcwi |
left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
11 |
|
94.77 |
mmHg |
5.77 |
19.15 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45742 |
461 |
FHH-Chr YBN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
5.48 |
mmHg |
0.07 |
0.23 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49190 |
461 |
FHH-Chr YBN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
|
5.45 |
ml/min/g |
0.42 |
1.34 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46214 |
461 |
FHH-Chr YBN/Mcwi |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
10 |
|
33.5 |
mmHg |
2.43 |
7.68 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48046 |
461 |
FHH-Chr YBN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
118.99 |
% |
6.77 |
20.32 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44931 |
461 |
FHH-Chr YBN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
10 |
|
19.68 |
IU/g |
2.85 |
9.02 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
48890 |
461 |
FHH-Chr YBN/Mcwi |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
10 |
|
950.9 |
s |
36.15 |
114.31 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50132 |
461 |
FHH-Chr YBN/Mcwi |
left ventricular diastolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
42.62 |
mmHg |
4.48 |
14.16 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46430 |
461 |
FHH-Chr YBN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
|
8.45 |
ml/min/g |
0.72 |
2.29 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46883 |
461 |
FHH-Chr YBN/Mcwi |
percent change in heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
80.78 |
% |
6.67 |
21.09 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48308 |
461 |
FHH-Chr YBN/Mcwi |
percent change in arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
51.19 |
% |
3.43 |
10.84 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47090 |
461 |
FHH-Chr YBN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
11 |
|
0.48 |
IU/g |
0.13 |
0.44 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47479 |
461 |
FHH-Chr YBN/Mcwi |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
|
1211.3 |
s |
34.15 |
107.98 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46561 |
461 |
FHH-Chr YBN/Mcwi |
left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
11 |
|
88.88 |
mmHg |
5.76 |
19.11 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48637 |
461 |
FHH-Chr YBN/Mcwi |
heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
11 |
|
245.52 |
beats/min |
5.91 |
19.62 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47595 |
461 |
FHH-Chr YBN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
|
198.21 |
beats/min |
8.72 |
26.16 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48958 |
461 |
FHH-Chr YBN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
98.64 |
mmHg |
3.88 |
11.63 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44828 |
461 |
FHH-Chr YBN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
66.53 |
% |
5.32 |
16.82 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46079 |
461 |
FHH-Chr YBN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
9 |
|
0.61 |
IU/g |
0.11 |
0.34 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47343 |
461 |
FHH-Chr YBN/Mcwi |
left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
37.42 |
mmHg |
5.25 |
16.61 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45283 |
461 |
FHH-Chr YBN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
|
234.2 |
beats/min |
10.62 |
31.87 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48210 |
461 |
FHH-Chr YBN/Mcwi |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
85.67 |
% |
4.73 |
14.18 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48419 |
461 |
FHH-Chr YBN/Mcwi |
arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
|
5.66 |
ml/min/g |
0.47 |
1.48 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
44731 |
461 |
FHH-Chr YBN/Mcwi |
time to onset of heart contraction |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
11 |
|
989.55 |
s |
38.56 |
127.89 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49312 |
461 |