Phenominer Database Results (507 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
ACI/SegHsd pituitary gland wet weight sham surgical control condition Strecker TE, et al., Genetics 2005 Jan 31;. pituitary gland mass male 147 days 6 0.01 g 0.0 0.0 post excision weight measurement 0.0 0 69100 1122
WKY.WKHA-(D5Rat45-D5Rat245)/Cfd time constant of left ventricular pressure decay sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 7.5 ms 0.6 1.34 vascular indwelling catheter method 0.0 0 68918 1014
WKY.WKHA-(D5Rat45-D5Rat245)/Cfd maximum rate of positive change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 10888.0 mmHg/s 484.0 1082.26 vascular indwelling catheter method 0.0 0 68894 1014
WKHA/Cfd maximum rate of positive change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 10484.0 mmHg/s 492.0 1100.15 vascular indwelling catheter method 0.0 0 68898 1014
WKY.WKHA-(D5Rat45-D5Rat245)/Cfd maximum rate of positive change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 9210.0 mmHg/s 296.0 661.88 vascular indwelling catheter method 0.0 0 68900 1014
WKHA/Cfd maximum rate of negative change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 6612.0 mmHg/s 308.0 688.71 vascular indwelling catheter method 0.0 0 68910 1014
SD heart rate sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart pumping trait male 0 days 6 380.0 beats/min 10.0 24.49 HP Sonos 5500 echo ultrasound 1.0 sham ACF 2 days 98802 2160
SD mean arterial blood pressure sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. arterial blood pressure trait male 0 days 6 76.0 mmHg 2.0 4.9 vascular transducer tipped catheter 1.0 sham ACF 2 days 98811 2160
SD mean arterial blood pressure sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. arterial blood pressure trait male 0 days 6 82.0 mmHg 3.0 7.35 vascular transducer tipped catheter 1.0 sham ACF 2 days 98817 2160
SR/JrHsd single kidney wet weight controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 1.05 g 0.03 post excision weight measurement 0.0 0 102196 2681
SS/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female 0 days 0 129.0 mmHg 5.0 vascular fluid filled catheter 0.0 0 102210 2681
SR/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 2.2 ml/min/g 0.31 inulin analysis by liquid phase colorimetry 0.0 0 102213 2681
SS/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91 days-119 days 6 140.3 mmol/l 1.3 3.18 flame atomic emission spectrometry 0.0 0 102253 2682
SR/Hsd plasma osmolality controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 298.7 umol/g 3.2 7.84 osmometry 0.0 0 p osmolality mosm/kg 102259 2682
Crl:WI(WU) mean arterial blood pressure sham surgical control condition Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91 days 14 105.0 mmHg 5.0 18.71 vascular fluid filled catheter 0.0 sham surgery 35 days 100013 2398
SD change in body weight sham surgical control condition (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. body mass male 0 days 6 84.0 g 4.9 12.0 body weighing method 0.0 sham unx 13 days change from surgery weight 101539 2602
SD systolic blood pressure sham surgical control condition (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male 0 days 6 undefined 118.0 mmHg 4.08 10.0 tail cuff plethysmography 0.0 sham unx 28 days 101583 2602
SD plasma potassium level sham surgical control condition (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. blood potassium amount male 0 days 6 5.0 mmol/l 0.24 0.6 ex vivo blood analysis 0.0 sham unx 28 days 101595 2602
WF/Mol heart left ventricle weight vehicle control condition then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart left ventricle mass male 0 days 6 0.21 g 0.0 0.01 post excision weight measurement 0.0 sham acf 2 days 101401 2585
SD left ventricular end-systolic blood pressure sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 64.0 mmHg 3.0 7.35 vascular transducer tipped catheter 1.0 sham ACF 2 days 98839 2160
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 7.3 mm 0.3 0.73 HP Sonos 5500 echo ultrasound 1.0 sham ACF 720 min 98845 2160
SD heart left ventricle end-systolic diameter sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-systolic diameter male 0 days 6 4.2 mm 0.3 0.73 HP Sonos 5500 echo ultrasound 1.0 sham ACF 360 min 98851 2160
SD heart left ventricle end-systolic diameter sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-systolic diameter male 0 days 6 4.0 mm 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 sham ACF 2 days 98855 2160
WF/Mol body weight gain vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 5 34.0 g 2.0 4.47 body weighing method 0.0 7 days change from surgery weight 101329 2585
SD ejection fraction sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. cardiac output trait male 72 days 5 72.0 % 2.0 4.47 echocardiography 0.0 sham ACF 2 days 99373 2278
SD body weight sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. body mass male 175 days 10 471.0 g 10.0 31.62 scale 0.0 sham ACF 105 days 99193 2278
SD heart weight sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart mass male 98 days 8 0.98 g 0.05 0.14 post excision weight measurement 0.0 sham ACF 28 days 99195 2278
SD mean arterial blood pressure sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. arterial blood pressure trait male 98 days 8 114.0 mmHg 4.0 11.31 vascular transducer tipped catheter 0.0 sham ACF 28 days 99219 2278
SD maximum rate of negative change in left ventricular blood pressure sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 8 -7479.0 mmHg/s 337.0 953.18 vascular transducer tipped catheter 0.0 sham ACF 28 days 99231 2278
SD heart weight to body weight ratio sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart mass male 189 days 6 2.66 g/kg 0.04 0.1 ex vivo method 0.0 sham lad occlusion 140 days 101086 2564
SD heart right ventricle weight sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart right ventricle mass male 77 days 6 0.23 g 0.01 0.02 ex vivo method 0.0 sham lad occlusion 28 days 101100 2564
SD heart right ventricle weight sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart right ventricle mass male 189 days 6 0.27 g 0.01 0.02 ex vivo method 0.0 sham lad occlusion 140 days 101102 2564
SD heart septum weight sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart septum morphology trait male 189 days 6 0.29 g 0.02 0.05 ex vivo method 0.0 sham lad occlusion 140 days septum 101126 2564
WF/Mol body weight controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 5 186.0 g 1.0 2.24 body weighing method 0.0 sham acf 7 days 101305 2585
WF/Mol body weight controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 6 184.0 g 2.0 4.9 body weighing method 0.0 sham acf 4 days 101315 2585
WF/Mol body weight controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 6 204.0 g 2.0 4.9 body weighing method 0.0 sham acf 7 days 101319 2585
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 175 days 10 9.0 mm 0.1 0.32 echocardiography 0.0 sham ACF 105 days 99237 2278
SD heart left ventricle end-systolic diameter sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-systolic diameter male 98 days 8 4.3 mm 0.3 0.85 echocardiography 0.0 sham ACF 28 days 99239 2278
SD plasma angiotensin II level sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. blood angiotensin II amount male 98 days 8 29.0 pg/ml 3.0 8.49 radioimmunoassay 0.0 sham ACF 28 days 99275 2278
SD maximum rate of positive change in left ventricular blood pressure sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 8505.0 mmHg/s 450.0 1190.59 vascular transducer tipped catheter 0.0 sham ACF 28 days 99327 2278
SD ejection fraction sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. cardiac output trait male 98 days 7 66.0 % 2.0 5.29 echocardiography 0.0 sham ACF 28 days 99375 2278
SD ejection fraction sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. cardiac output trait male 98 days 7 67.0 % 2.0 5.29 echocardiography 0.0 sham ACF 28 days 99377 2278
SD left ventricle end-diastolic wall stress sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 4.0 g/cm2 1.0 2.65 echocardiography 0.0 sham ACF 28 days 99391 2278
WKY heart rate sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart pumping trait male 266 days-280 days 5 398.0 beats/min 37.0 82.73 echocardiography 0.0 lad occlusion sham 210 days 100312 2460
WKY ejection fraction sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. cardiac output trait male 238 days-252 days 12 75.8 % 3.9 13.51 echocardiography 0.0 lad occlusion sham 196 days 100351 2460
SHR-Chr 6MWF/Rkb urine albumin excretion rate sham surgical control condition Schulz A, etal., Physiol Genomics. 2010 Jun. urine albumin amount male 168 days 10 0.5 mg/d 0.2 0.63 enzyme linked immunosorbent assay 0.0 0 108127 3116
SHR/FubRkb body weight sham surgical control condition (for 126 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. body mass male 168 days 9 329.2 g 8.2 24.6 body weighing method 0.0 0 109549 3148
SHR/FubRkb right kidney wet weight sham surgical control condition (for 126 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. kidney mass male 168 days 9 1.07 g 0.05 0.15 post excision weight measurement kidney 0.0 0 109553 3148
SHR-Chr 8MWF/Rkb urine albumin excretion rate sham surgical control condition (for 42 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. urine albumin amount male 84 days 9 1.3 mg/d 0.2 0.6 enzyme linked immunosorbent assay 0.0 0 109564 3148
MWF/Hsd systemic vascular resistance sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. arterial blood pressure trait male 168 days 9 0.81 mmHg/ml/min 0.07 0.21 vascular indwelling catheter method 0.0 0 108892 3130
HsdCpb:WU renal vascular resistance sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. arterial blood pressure trait male 175 days 10 13.2 mmHg/ml/min 1.9 6.01 vascular indwelling catheter method 0.0 0 108894 3130
MWF/Hsd renal vascular resistance sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. arterial blood pressure trait male 175 days 9 52.8 mmHg/ml/min 13.1 39.3 vascular indwelling catheter method 0.0 0 108895 3130
MWF/Hsd left ventricular systolic blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart left ventricular blood pressure trait male 175 days 9 134.0 mmHg 3.0 9.0 vascular indwelling catheter method heart left ventricle 0.0 0 108848 3130
HsdCpb:WU hematocrit sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. erythrocyte quantity male 175 days 10 47.8 % 0.6 1.9 hematocrit analysis 0.0 0 108802 3130
HsdCpb:WU plasma chloride level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. blood chloride amount male 175 days 10 102.0 mmol/l 1.0 3.16 automated blood electrolyte analysis 0.0 0 108814 3130
MWF/Hsd plasma chloride level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. blood chloride amount male 175 days 9 105.0 mmol/l 1.0 3.0 automated blood electrolyte analysis 0.0 0 108816 3130
HsdCpb:WU urine sodium level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. urine sodium amount male 175 days 10 92.0 mmol/l 17.0 53.76 automated urine sodium analysis 0.0 0 108818 3130
HsdCpb:WU urine potassium level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. urine potassium amount male 175 days 10 115.0 mmol/l 15.0 47.43 urine potassium analysis 0.0 0 108822 3130
GK/MolTac blood hemoglobin A1c level sham surgical control condition (for 126 days) then sodium bicarbonate (8.4 %) (for 112 days) Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. blood glucose amount male 224 days 9 5.5 % 0.3 0.9 blood hemoglobin analysis 0.0 sham surgery 105 days 110760 3183
SHRSP/A3NCrl partial pressure of brain white matter oxygen sham surgical control condition then standard diet Weaver J, etal., J Cereb Blood Flow Metab. 2014 May;34(5):890-6. doi: 10.1038/jcbfm.2014.35. Epub 2014 Feb 19. brain oxygen amount male 84 days 8 41.8 mmHg 2.5 7.07 electron paramagnetic resonance oximetry white matter 40.0 0 5 scans x 40 seconds partial pressure of brain white matter oxygen (CMO:0003626) 107319 3080
SHRSP/A3NCrl partial pressure of brain white matter oxygen sham surgical control condition then standard diet Weaver J, etal., J Cereb Blood Flow Metab. 2014 May;34(5):890-6. doi: 10.1038/jcbfm.2014.35. Epub 2014 Feb 19. brain oxygen amount male 112 days 8 15.4 mmHg 3.8 10.75 electron paramagnetic resonance oximetry white matter 40.0 0 5 scans x 40 seconds partial pressure of brain white matter oxygen (CMO:0003626) 107324 3080
MWF/FubRkb urine total protein excretion rate sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. total urine protein amount not specified 84 days 15 79.1 mg/d 9.5 36.79 urine total protein analysis 0.0 0 109652 3149
HsdCpb:WU kidney interstitial fibrotic lesion area to total kidney area ratio sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. kidney integrity trait not specified 86 days 15 4.2 % 0.1 0.39 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 109676 3149
MWF/FubRkb kidney interstitial fibrotic lesion area to total kidney area ratio sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. kidney integrity trait not specified 86 days 15 5.0 % 0.4 1.55 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 109677 3149
SHR/NHsd artery lumen area sham surgical control condition Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252. iliac artery morphology trait male 119 days-133 days 12 0.34 mm2 0.23 0.78 ex vivo light microscopy with digital image analysis 0.0 0 110500 3107
WAG/RijCrl number of medium-sized metastatic liver tumors S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days) Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2. liver integrity trait male 87 days 10 4.3 null 1.1 3.48 ex vivo caliper method 0.0 S4MH injection 21 days metastatic liver tumor count by size 108153 3119
WAG/RijCrl number of large metastatic liver tumors S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days) Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2. liver integrity trait male 87 days 10 3.3 null 1.5 4.74 ex vivo caliper method 0.0 S4MH injection 21 days metastatic liver tumor count by size 108154 3119
WAG/RijCrl metastatic liver tumor number S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days) Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2. liver integrity trait male 87 days 10 9.3 null 2.5 7.91 ex vivo caliper method 0.0 S4MH injection 21 days metastatic liver tumor count by size 108155 3119
WAG/RijCrl metastatic lung tumor number S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days) Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2. lung integrity trait male 87 days 10 28.5 null 7.68 24.29 ex vivo visual assessment 0.0 S4MH injection 21 days 108162 3119
WKY/Cfd left ventricular end-diastolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 1.66 mmHg 0.62 1.39 vascular indwelling catheter method 0.0 0 68808 1014
SD heart left ventricle weight to body weight ratio sham surgical control condition (for 12 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle mass male 0 days 6 g/g*103 2.3 mg/g 0.1 0.24 post excision weight measurement 1.0 sham ACF 720 min 98788 2160
SD heart rate sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart pumping trait male 0 days 6 385.0 beats/min 11.0 26.94 HP Sonos 5500 echo ultrasound 1.0 sham ACF 360 min 98794 2160
SD heart rate sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart pumping trait male 0 days 6 395.0 beats/min 11.0 26.94 HP Sonos 5500 echo ultrasound 1.0 sham ACF 720 min 98796 2160
SD left ventricular end-diastolic blood pressure sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 2.0 mmHg 1.0 2.45 vascular transducer tipped catheter 1.0 sham ACF 5 days 98825 2160
SD body weight sham surgical control condition (for 12 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. body mass male 0 days 6 271.0 g 6.0 14.7 body weighing method 1.0 sham ACF 720 min 98772 2160
SD heart weight to body weight ratio sham surgical control condition (for 12 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart mass male 0 days 6 g/g*103 3.4 g/kg 0.1 0.24 post excision weight measurement 1.0 sham ACF 720 min 98780 2160
GK body weight sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. body mass female 87 days 6 229.0 g 5.0 12.25 body weighing method 0.0 0 103755 2782
Crl:WI(Han) plasma low density lipoprotein cholesterol level sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. blood LDL cholesterol amount female 87 days 6 0.21 mg/dl 0.01 0.02 plasma low-density lipoprotein-cholesterol measurement test 0.0 0 automated plasma low-density lipoprotein-cholesterol analysis 103769 2782
SD urine total protein excretion rate sham surgical control condition (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. total urine protein amount male 0 days 6 19.0 mg/d 2.45 6.0 urine protein analysis 0.0 sham unx 28 days 101591 2602
WF/Mol heart rate controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male 0 days 5 402.0 beats/min 31.0 69.32 tail cuff plethysmography 0.0 sham acf 7 days 101371 2585
WF/Mol heart left ventricle weight controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart left ventricle mass male 0 days 6 0.21 g 0.01 0.01 post excision weight measurement 0.0 sham acf 4 days 101403 2585
WF/Mol heart right ventricle weight vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart right ventricle mass male 0 days 6 0.05 g 0.0 0.0 post excision weight measurement 0.0 sham acf 7 days 101431 2585
WF/Mol body weight vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 5 180.0 g 2.0 4.47 body weighing method 0.0 7 days 101307 2585
WKY left ventricular end-systolic blood pressure sham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricular blood pressure trait male 266 days-280 days 5 10 min mean continuous mean 93.0 mmHg 5.8 12.97 vascular transducer tipped catheter 0.0 lad occlusion sham 210 days 100321 2460
WKY heart posterior wall thickness sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle posterior wall thickness male 238 days-252 days 12 0.17 cm 0.01 0.03 echocardiography 0.0 lad occlusion sham 196 days 100345 2460
SD maximum rate of negative change in left ventricular blood pressure sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 -7197.0 mmHg/s 303.0 742.2 vascular transducer tipped catheter 1.0 sham ACF 2 days 98891 2160
SD mean arterial blood pressure sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. arterial blood pressure trait male 72 days 5 106.0 mmHg 1.0 2.24 vascular transducer tipped catheter 0.0 sham ACF 2 days 99301 2278
SD left ventricular end-systolic blood pressure sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 72 days 5 55.0 mmHg 3.0 6.71 vascular transducer tipped catheter 0.0 sham ACF 2 days 99315 2278
SD maximum rate of positive change in left ventricular blood pressure sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 72 days 5 8767.0 mmHg/s 391.0 874.3 vascular transducer tipped catheter 0.0 sham ACF 2 days 99323 2278
SD maximum rate of negative change in left ventricular blood pressure sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 -7422.0 mmHg/s 236.0 624.4 vascular transducer tipped catheter 0.0 sham ACF 28 days 99336 2278
ACI/SegHsd binary logarithm of pituitary gland wet weight sham surgical control condition (between 193 and 199 days) Shull JD, et al., Mamm Genome. 2007 Sep 18;. pituitary gland mass female 252 days-266 days 10 3.13 null 0.06 0.19 post excision weight measurement pituitary gland 0 0 logarithm of pituitary wet weight 65771 331
WKY.WKHA-(D5Rat45-D5Rat245)/Cfd left ventricular end-diastolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 0.52 mmHg 0.27 0.6 vascular indwelling catheter method 0.0 0 68806 1014
WKHA/Cfd time constant of left ventricular pressure decay sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 13.5 ms 1.8 4.02 vascular indwelling catheter method 0.0 0 68922 1014
WKHA/Cfd left ventricular end-diastolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 1.99 mmHg 0.42 0.94 vascular indwelling catheter method 0.0 0 68857 1014
WKHA/Cfd left ventricular end-systolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 126.0 mmHg 5.17 11.56 vascular indwelling catheter method 0.0 0 68863 1014
WKY.WKHA-(D5Rat45-D5Rat245)/Cfd left ventricular end-systolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 139.9 mmHg 4.8 10.73 vascular indwelling catheter method 0.0 0 68865 1014
WKHA/Cfd maximum rate of positive change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 9127.0 mmHg/s 286.0 639.52 vascular indwelling catheter method 0.0 0 68892 1014
WKY/Cfd maximum rate of negative change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 6808.0 mmHg/s 588.0 1314.81 vascular indwelling catheter method 0.0 0 "rate of maximum negative change in left ventricular blood pressure" mmHg/s 68902 1014
WKHA/Cfd maximum rate of negative change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 5901.0 mmHg/s 507.0 1133.69 vascular indwelling catheter method 0.0 0 68904 1014
WKY body weight sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. body mass male 266 days-280 days 5 562.0 g 22.0 49.19 body weighing method 0.0 lad occlusion sham 210 days 100273 2460
WKY heart weight sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart mass male 238 days-252 days 12 1.19 g 0.04 0.13 post excision weight measurement 0.0 lad occlusion sham 196 days 100276 2460
WKY heart left ventricle weight sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle mass male 266 days-280 days 5 0.84 g 0.02 0.05 post excision weight measurement 0.0 lad occlusion sham 210 days 100291 2460
SR/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female 0 days 0 122.0 mmHg 4.0 vascular fluid filled catheter 0.0 0 102207 2681
SS/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 2.46 ml/min/g 0.06 inulin analysis by liquid phase colorimetry 0.0 0 102216 2681
WF/Mol systolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male 0 days 6 undefined 143.0 mmHg 5.0 12.25 tail cuff plethysmography 0.0 sham acf 4 days 101359 2585
WF/Mol systolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male 0 days 6 undefined 130.0 mmHg 3.0 7.35 tail cuff plethysmography 0.0 sham acf 7 days 101363 2585
WF/Mol systolic blood pressure vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male 0 days 5 undefined 165.0 mmHg 7.0 15.65 tail cuff plethysmography 0.0 sham acf 7 days 101365 2585
WF/Mol heart left ventricle weight vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart left ventricle mass male 0 days 6 0.2 g 0.0 0.01 post excision weight measurement 0.0 sham acf 7 days 101409 2585
SD adrenal gland weight sham surgical control condition (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. adrenal gland mass male 0 days 6 46.0 mg 0.82 2.0 post excision weight measurement 0.0 sham unx 28 days 101599 2602
SD kidney sclerotic glomeruli count to total glomeruli count ratio sham surgical control condition (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. kidney glomerulus integrity trait male 0 days 6 1.9 % 0.49 1.2 ex vivo light microscopy with histochemistry 0.0 sham unx 28 days 101603 2602
WF/Mol body weight gain controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 6 8.0 g 2.0 4.9 body weighing method 0.0 sham acf 7 days change from surgery weight 101341 2585
WF/Mol heart rate vehicle control condition then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male 0 days 6 377.0 beats/min 11.0 26.94 tail cuff plethysmography 0.0 sham acf 2 days 101379 2585
WF/Mol heart rate controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male 0 days 6 410.0 beats/min 8.0 19.6 tail cuff plethysmography 0.0 sham acf 4 days 101381 2585
SD systolic blood pressure sham surgical control condition (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male 0 days 6 undefined 118.0 mmHg 3.67 9.0 tail cuff plethysmography 0.0 sham unx 13 days 101547 2602
SD left kidney wet weight sham surgical control condition (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. kidney mass male 0 days 6 1.19 g 0.03 0.08 post excision weight measurement 0.0 sham unx 28 days remnant kidney 101579 2602
SS/JrHsd both kidneys wet weight controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days) Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13. kidney mass female 112 days 6 1.77 g 0.04 0.1 post excision weight measurement 0.0 sham ovx 63 days 102346 2686
WF/Mol heart rate vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male 0 days 5 382.0 beats/min 8.0 17.89 tail cuff plethysmography 0.0 sham acf 7 days 101388 2585
WF/Mol heart left ventricle weight controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart left ventricle mass male 0 days 5 0.19 g 0.01 0.01 post excision weight measurement 0.0 sham acf 4 days 101389 2585
SD heart left ventricle end-systolic diameter sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-systolic diameter male 0 days 6 3.9 mm 0.3 0.73 HP Sonos 5500 echo ultrasound 1.0 sham ACF 5 days 98857 2160
SD heart left ventricle end-diastolic posterior wall thickness sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle posterior wall thickness male 0 days 6 1.6 mm 0.1 0.24 HP Sonos 5500 echo ultrasound 1.0 sham ACF 5 days 98865 2160
SD maximum rate of positive change in left ventricular blood pressure sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 8231.0 mmHg/s 423.0 1036.13 vascular transducer tipped catheter 1.0 sham ACF 2 days 98887 2160
Crl:WI(WU) mean arterial blood pressure sham surgical control condition Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91 days 14 103.0 mmHg 5.0 18.71 vascular fluid filled catheter 0.0 sham surgery 35 days 100021 2398
WKY plasma creatinine level sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. blood creatinine amount male 238 days-252 days 6 0.41 mg/dl 0.03 0.07 plasma creatinine analysis 0.0 lad occlusion sham 196 days 100377 2460
SD heart left ventricle fractional shortening sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 7 38.0 % 2.0 5.29 echocardiography 0.0 sham ACF 28 days 99367 2278
SD heart weight to body weight ratio sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart mass male 98 days 8 2.7 g/kg 0.1 0.28 post excision weight measurement 0.0 sham ACF 28 days 99199 2278
SD heart left ventricle weight to body weight ratio sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle mass male 175 days 10 1.9 mg/g 0.1 0.32 post excision weight measurement 0.0 sham ACF 105 days 99205 2278
SD maximum rate of positive change in left ventricular blood pressure sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 175 days 10 7529.0 mmHg/s 445.0 1407.21 vascular transducer tipped catheter 0.0 sham ACF 105 days 99229 2278
SD left ventricle end-diastolic wall stress sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 8 3.0 g/cm2 1.0 2.83 echocardiography 0.0 sham ACF 28 days 99247 2278
SD left ventricle end-systolic wall stress sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 175 days 10 72.0 g/cm2 7.0 22.14 echocardiography 0.0 sham ACF 105 days 99253 2278
SD heart left ventricle fractional shortening sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 8 38.0 % 4.0 11.31 echocardiography 0.0 sham ACF 28 days 99255 2278
SD heart left ventricle interstitial angiotensin II level during a period of time sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle interstitial angiotensin II amount male 98 days 8 1.5 pg/hr 0.2 0.57 radioimmunoassay 0.0 sham ACF 28 days heart left ventricle interstitial angiotensin II level during a period of time 99259 2278
SD heart left ventricle interstitial angiotensin II level during a period of time sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle interstitial angiotensin II amount male 175 days 8 1.6 pg/hr 0.2 0.57 radioimmunoassay 0.0 sham ACF 105 days heart left ventricle interstitial angiotensin II level during a period of time 99261 2278
SD heart left ventricle interstitial norepinephrine level during a period of time sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle interstitial norepinephrine amount male 98 days 8 6.2 pg/hr 1.0 2.83 enzyme linked immunosorbent assay 0.0 sham ACF 28 days heart left ventricle interstitial bradykinin level during a period of time 99267 2278
SD heart left ventricle interstitial epinephrine level during a period of time sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle interstitial epinephrine amount male 175 days 8 3.5 pg/hr 0.4 1.13 enzyme linked immunosorbent assay 0.0 sham ACF 105 days heart left ventricle interstitial epinephrine level during a period of time 99273 2278
SD plasma bradykinin level sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. blood bradykinin amount male 98 days 8 10.0 pg/ml 1.0 2.83 radioimmunoassay 0.0 sham ACF 28 days pl bk 99279 2278
SD plasma norepinephrine level sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. blood norepinephrine amount male 98 days 8 93.0 pg/ml 12.0 33.94 enzyme linked immunosorbent assay 0.0 sham ACF 28 days pl bk 99283 2278
SD plasma epinephrine level sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. blood epinephrine amount male 98 days 8 83.0 pg/ml 12.0 33.94 enzyme linked immunosorbent assay 0.0 sham ACF 28 days 99287 2278
SD heart rate sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart pumping trait male 72 days 5 359.0 beats/min 6.0 13.42 vascular transducer tipped catheter 0.0 sham ACF 2 days 99291 2278
SD left ventricular end-systolic blood pressure sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 86.0 mmHg 5.0 13.23 vascular transducer tipped catheter 0.0 sham ACF 28 days 99321 2278
SD maximum rate of positive change in left ventricular blood pressure sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 7931.0 mmHg/s 415.0 1097.99 vascular transducer tipped catheter 0.0 sham ACF 28 days 99329 2278
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 7 7.7 mm 0.2 0.53 echocardiography 0.0 sham ACF 28 days 99343 2278
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 7 7.6 mm 0.1 0.26 echocardiography 0.0 sham ACF 28 days 99345 2278
SD heart left ventricle end-systolic diameter sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-systolic diameter male 98 days 7 4.7 mm 0.2 0.53 echocardiography 0.0 sham ACF 28 days 99353 2278
SD heart left ventricle weight to body weight ratio sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart left ventricle mass male 77 days 6 1.56 mg/g 0.03 0.07 ex vivo method 0.0 sham lad occlusion 28 days 101096 2564
SD heart left atrium weight to body weight ratio sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart left atrium mass male 189 days 6 0.08 mg/g 0.01 0.01 ex vivo method 0.0 sham lad occlusion 140 days law/bw 101114 2564
WF/Mol body weight controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 5 193.0 g 3.0 6.71 body weighing method 0.0 sham acf 4 days 101301 2585
WF/Mol body weight gain controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 5 20.0 g 2.0 4.47 body weighing method 0.0 sham acf 4 days change from surgery weight 101323 2585
WF/Mol body weight gain controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 5 30.0 g 2.0 4.47 body weighing method 0.0 sham acf 7 days change from surgery weight 101327 2585
WKY serum potassium level sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. blood potassium amount male 266 days-280 days 5 5.3 mmol/l 0.37 0.83 automated serum potassium test 0.0 lad occlusion sham 210 days 100333 2460
WKY heart ventricle septal wall thickness sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle wall thickness male 238 days-252 days 12 0.14 cm 0.01 0.03 echocardiography 0.0 lad occlusion sham 196 days 100336 2460
WKY heart left ventricle end-systolic diameter sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-systolic diameter male 238 days-252 days 12 4.9 mm 0.3 1.04 echocardiography 0.0 lad occlusion sham 196 days 100342 2460
SD left ventricle end-diastolic wall stress sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 72 days 5 4.0 g/cm2 1.0 2.24 echocardiography 0.0 sham ACF 2 days lved-ws 99387 2278
MWF/FubRkb urine albumin excretion rate sham surgical control condition Schulz A, etal., Physiol Genomics. 2010 Jun. urine albumin amount male 84 days 10 22.8 mg/d 2.1 6.64 enzyme linked immunosorbent assay 0.0 0 108123 3116
HsdCpb:WU mean arterial blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. arterial blood pressure trait male 84 days 5 89.0 mmHg 4.0 8.94 vascular indwelling catheter method aorta 0.0 0 108772 3130
MWF/Hsd mean arterial blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. arterial blood pressure trait male 84 days 5 102.0 mmHg 3.0 6.71 vascular indwelling catheter method aorta 0.0 0 108773 3130
MWF/Hsd left ventricular end-diastolic blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart left ventricular blood pressure trait male 84 days 5 6.2 mmHg 1.9 4.25 vascular indwelling catheter method heart left ventricle 0.0 0 108777 3130
MWF/Hsd renal blood flow rate to kidney weight ratio sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. arterial blood pressure trait male 175 days 9 2.8 ml/min/g 0.7 2.1 flowmetry renal artery 0.0 0 108860 3130
MWF/Hsd cardiac myocyte cross-sectional area sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. cardiomyocyte morphology trait male 84 days 5 535.0 um2 71.0 158.76 ex vivo light microscopy with histochemistry and digital image analysis heart left ventricle 0.0 0 cardiac myocyte cross-sectional area (CMO:0003840) 108900 3130
SHR-Chr 8MWF/Rkb body weight sham surgical control condition (for 126 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. body mass male 168 days 9 345.0 g 7.8 23.4 body weighing method 0.0 0 109551 3148
SHR/FubRkb right kidney wet weight to body weight ratio sham surgical control condition (for 126 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. kidney mass male 168 days 9 3.25 mg/g 0.09 0.27 post excision weight measurement kidney 0.0 0 109557 3148
SHR/FubRkb urine albumin excretion rate sham surgical control condition Schulz A, etal., Physiol Genomics. 2010 Jun. urine albumin amount male 84 days 10 0.4 mg/d 0.1 0.32 enzyme linked immunosorbent assay 0.0 0 108125 3116
MWF/Hsd food intake rate sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. eating behavior trait male 175 days 9 13.0 g/d 1.0 3.0 food intake measuring method 0.0 0 108792 3130
MWF/Hsd timed urine volume sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. urine output male 175 days 9 13.0 ml/d 1.0 3.0 metabolic cage urine volume measurement method 0.0 0 108800 3130
HsdCpb:WU plasma sodium level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. blood sodium amount male 175 days 10 137.0 mmol/l 1.0 3.16 automated blood electrolyte analysis 0.0 0 108806 3130
MWF/Hsd urine sodium level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. urine sodium amount male 175 days 9 147.0 mmol/l 11.0 33.0 automated urine sodium analysis 0.0 0 108820 3130
MWF/Hsd blood B-type natriuretic peptide level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. blood protein amount male 133 days 5 0.3 ng/ml 0.4 0.89 enzyme immunoassay 0.0 0 blood B-type natriuretic peptide level (CMO:0003868) 108883 3130
HsdCpb:WU creatinine clearance sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. glomerular filtration trait not specified 84 days 15 2.76 ml/min 0.17 0.66 urine creatinine analysis 0.0 0 109645 3149
HsdCpb:WU heart left ventricle perivascular fibrotic lesion area to total heart left ventricule area ratio sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. heart left ventricle integrity trait not specified 86 days 15 10.0 % 1.2 4.65 ex vivo light microscopy with histochemistry and digital image analysis heart left ventricle 0.0 0 109670 3149
BDIX/OrlCrl ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (for 30 days) Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7. liver integrity trait male 0 days 12 56.5 % 7.2 24.94 ex vivo light microscopy with immunohistochemistry liver 0.0 37 days sham surgical group POD30 sham surgical group POD30 110819 3191
WAG/RijCrl number of small metastatic liver tumors S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days) Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2. liver integrity trait male 87 days 10 1.7 null 0.9 2.85 ex vivo caliper method 0.0 S4MH injection 21 days metastatic liver tumor count by size 108152 3119
WKHA/Cfd time constant of left ventricular pressure decay sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 13.3 ms 0.27 0.6 vascular indwelling catheter method 0.0 0 68916 1014
WKY/Cfd left ventricular end-diastolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 1.32 mmHg 0.3 0.67 vascular indwelling catheter method 0.0 0 68802 1014
SS/JrHsd plasma estradiol level controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days) Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13. blood estradiol amount female 112 days 6 15.7 pg/ml 1.7 4.16 radioimmunoassay 0.0 sham ovx 63 days 102358 2686
SR/JrHsd plasma estradiol level controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days) Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13. blood estradiol amount female 112 days 6 17.1 pg/ml 4.6 11.27 radioimmunoassay 0.0 sham ovx 63 days 102361 2686
SD heart left ventricle weight to body weight ratio sham surgical control condition (between 120 and 12 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle mass male 0 days 6 g/g*103 2.3 mg/g 0.1 0.24 post excision weight measurement 1.0 sham ACF 5 days 98792 2160
SD mean arterial blood pressure sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. arterial blood pressure trait male 0 days 6 103.0 mmHg 6.0 14.7 vascular transducer tipped catheter 1.0 sham ACF 360 min 98807 2160
SD left ventricle end-diastolic wall stress sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 175 days 10 7.0 g/cm2 1.0 3.16 echocardiography 0.0 sham ACF 105 days 99249 2278
MWF/FubRkb creatinine clearance sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. glomerular filtration trait not specified 84 days 15 2.36 ml/min 0.14 0.54 urine creatinine analysis 0.0 0 109646 3149
SD left ventricular end-diastolic blood pressure sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 3.0 mmHg 1.0 2.45 vascular transducer tipped catheter 1.0 sham ACF 2 days 98827 2160
SD heart left ventricle end-diastolic diameter to posterior wall thickness ratio sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 4.6 null 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 sham ACF 2 days heart left ventricle end-diastolic diameter to posterior wall thickness ratio 98871 2160
SD ejection fraction sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. cardiac output trait male 0 days 6 63.0 % 3.0 7.35 HP Sonos 5500 echo ultrasound 1.0 sham ACF 720 min 98881 2160
GK plasma insulin level sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. blood insulin amount female 87 days 6 26.0 mU/l 2.6 6.37 enzyme linked immunosorbent assay 0.0 0 103763 2782
GK plasma low density lipoprotein cholesterol level sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. blood LDL cholesterol amount female 87 days 6 0.23 mg/dl 0.02 0.05 plasma low-density lipoprotein-cholesterol measurement test 0.0 0 automated plasma low-density lipoprotein-cholesterol analysis 103771 2782
SD heart rate sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart pumping trait male 72 days 5 371.0 beats/min 4.0 8.94 vascular transducer tipped catheter 0.0 sham ACF 2 days 99293 2278
SD left ventricular end-systolic blood pressure sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 72 days 5 58.0 mmHg 2.0 4.47 vascular transducer tipped catheter 0.0 sham ACF 2 days 99317 2278
SD heart left ventricle end-systolic diameter sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-systolic diameter male 72 days 5 4.0 mm 0.2 0.45 echocardiography 0.0 sham ACF 2 days 99347 2278
SD heart left ventricle end-diastolic diameter to posterior wall thickness ratio sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 7 lvedd/pw 4.5 null 0.4 1.06 echocardiography 0.0 sham ACF 28 days heart left ventricle end-diastolic diameter to posterior wall thickness ratio 99361 2278
SD heart left ventricle fractional shortening sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 72 days 5 43.0 % 2.0 4.47 echocardiography 0.0 sham ACF 2 days 99365 2278
SD left ventricle end-systolic wall stress sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 68.0 g/cm2 8.0 21.17 echocardiography 0.0 sham ACF 28 days 99401 2278
WKY heart left ventricle fractional shortening sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-diastolic diameter male 266 days-280 days 5 51.5 % 1.7 3.8 echocardiography 0.0 lad occlusion sham 210 days 100303 2460
WKY heart left ventricle end-diastolic diameter sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-diastolic diameter male 266 days-280 days 5 7.9 mm 0.2 0.45 echocardiography 0.0 lad occlusion sham 210 days 100306 2460
WKY systolic blood pressure sham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. arterial blood pressure trait male 266 days-280 days 5 10 min mean continuous mean 97.8 mmHg 6.3 14.09 vascular transducer tipped catheter 0.0 lad occlusion sham 210 days 100315 2460
SD right atrium weight sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart right atrium mass male 77 days 6 0.04 g 0.0 0.0 ex vivo method 0.0 sham lad occlusion 28 days 101116 2564
WKHA/Cfd left ventricular end-diastolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 0.23 mmHg 0.46 1.03 vascular indwelling catheter method 0.0 0 68804 1014
COP/CrCrl pituitary gland wet weight sham surgical control condition Strecker TE, et al., Genetics 2005 Jan 31;. pituitary gland mass male 147 days 8 0.01 g 0.0 0.0 post excision weight measurement 0.0 0 69106 1122
WKY.WKHA-(D5Rat45-D5Rat245)/Cfd time constant of left ventricular pressure decay sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 7.5 ms 0.9 2.01 vascular indwelling catheter method 0.0 0 68924 1014
WKY/Cfd left ventricular end-systolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 125.3 mmHg 4.1 9.17 vascular indwelling catheter method 0.0 0 68861 1014
WKHA/Cfd left ventricular end-systolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 131.0 mmHg 5.0 11.18 vascular indwelling catheter method 0.0 0 68869 1014
SD mean arterial blood pressure sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. arterial blood pressure trait male 0 days 6 90.0 mmHg 5.0 12.25 vascular transducer tipped catheter 1.0 sham ACF 720 min 98809 2160
SD mean arterial blood pressure sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. arterial blood pressure trait male 0 days 6 85.0 mmHg 3.0 7.35 vascular transducer tipped catheter 1.0 sham ACF 5 days 98813 2160
Crl:WI(WU) body weight sham surgical control condition Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. body mass male 91 days 14 334.0 g 8.0 29.93 body weighing method 0.0 sham surgery 35 days 100005 2398
SR/JrHsd body weight controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 226.0 g 4.7 body weighing method 0.0 0 102183 2681
WF/Mol systolic blood pressure controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male 0 days 5 undefined 106.0 mmHg 4.0 8.94 tail cuff plethysmography 0.0 sham acf 4 days 101345 2585
Crl:WI(Han) plasma total cholesterol level sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. blood cholesterol amount female 87 days 6 2.49 mg/dl 0.17 0.42 plasma total cholesterol measurement test 0.0 0 automated plasma total cholesterol analysis 103765 2782
GK plasma total cholesterol level sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. blood cholesterol amount female 87 days 6 2.53 mg/dl 0.14 0.34 plasma total cholesterol measurement test 0.0 0 automated plasma total cholesterol analysis 103767 2782
GK plasma estradiol level sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. blood estradiol amount female 87 days 6 49.6 pg/ml 3.7 9.06 enzyme linked immunosorbent assay 0.0 0 103775 2782
WF/Mol systolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male 0 days 5 undefined 151.0 mmHg 5.0 11.18 tail cuff plethysmography 0.0 sham acf 2 days 101355 2585
WF/Mol heart rate vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male 0 days 5 406.0 beats/min 22.0 49.19 tail cuff plethysmography 0.0 sham acf 4 days 101369 2585
WF/Mol heart rate vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male 0 days 5 358.0 beats/min 12.0 26.83 tail cuff plethysmography 0.0 sham acf 7 days 101373 2585
SS/Hsd plasma osmolality controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 299.4 umol/g 3.8 9.31 osmometry 0.0 0 p osmolality mosm/kg 102263 2682
SD left ventricular end-systolic blood pressure sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 58.0 mmHg 3.0 7.35 vascular transducer tipped catheter 1.0 sham ACF 360 min 98831 2160
SD left ventricular end-systolic blood pressure sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 62.0 mmHg 2.0 4.9 vascular transducer tipped catheter 1.0 sham ACF 720 min 98833 2160
SD left ventricular end-systolic blood pressure sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 66.0 mmHg 3.0 7.35 vascular transducer tipped catheter 1.0 sham ACF 2 days 98835 2160
SD left ventricular end-systolic blood pressure sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 58.0 mmHg 2.0 4.9 vascular transducer tipped catheter 1.0 sham ACF 5 days 98837 2160
SD left ventricular end-systolic blood pressure sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 64.0 mmHg 3.0 7.35 vascular transducer tipped catheter 1.0 sham ACF 2 days 98841 2160
SD ejection fraction sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. cardiac output trait male 0 days 6 65.0 % 3.0 7.35 HP Sonos 5500 echo ultrasound 1.0 sham ACF 2 days 98883 2160
SS/JrHsd uterus weight controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days) Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13. uterus mass female 112 days 6 0.44 g 0.02 0.05 post excision weight measurement 0.0 sham ovx 63 days 102352 2686
SD heart weight to body weight ratio sham surgical control condition (between 120 and 12 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart mass male 0 days 6 g/g*103 3.4 g/kg 0.1 0.24 post excision weight measurement 1.0 sham ACF 5 days 98784 2160
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 7.2 mm 0.3 0.73 HP Sonos 5500 echo ultrasound 1.0 sham ACF 360 min 98843 2160
SD heart left ventricle end-diastolic posterior wall thickness sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle posterior wall thickness male 0 days 6 1.6 mm 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 sham ACF 720 min 98861 2160
WF/Mol heart right ventricle weight controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart right ventricle mass male 0 days 5 0.06 g 0.0 0.01 post excision weight measurement 0.0 sham acf 4 days 101411 2585
WF/Mol heart right ventricle weight vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart right ventricle mass male 0 days 5 0.06 g 0.0 0.0 post excision weight measurement 0.0 sham acf 7 days 101417 2585
SD body weight sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. body mass male 98 days 8 359.0 g 20.0 56.57 scale 0.0 sham ACF 28 days 99191 2278
SD heart weight sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart mass male 175 days 10 1.26 g 0.03 0.09 post excision weight measurement 0.0 sham ACF 105 days 99197 2278
SD heart weight to body weight ratio sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart mass male 175 days 10 2.7 g/kg 0.1 0.32 post excision weight measurement 0.0 sham ACF 105 days 99201 2278
SD heart left ventricle weight to body weight ratio sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle mass male 98 days 8 2.1 mg/g 0.1 0.28 post excision weight measurement 0.0 sham ACF 28 days 99203 2278
SD heart right ventricle weight to body weight ratio sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart right ventricle mass male 98 days 8 0.5 mg/g 0.1 0.28 post excision weight measurement 0.0 sham ACF 28 days 99207 2278
SD lung weight sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. lung mass male 98 days 8 1.46 g 0.09 0.25 post excision weight measurement 0.0 sham ACF 28 days 99211 2278
SD heart rate sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart pumping trait male 175 days 10 217.0 beats/min 12.0 37.95 vascular transducer tipped catheter 0.0 sham ACF 105 days 99217 2278
SD left ventricular end-diastolic blood pressure sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 8 2.0 mmHg 1.0 2.83 vascular transducer tipped catheter 0.0 sham ACF 28 days 99223 2278
WF/Mol body weight gain controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 6 -1.0 g 1.0 2.45 body weighing method 0.0 sham acf 4 days change from surgery weight 101337 2585
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 8 7.0 mm 0.2 0.57 echocardiography 0.0 sham ACF 28 days 99235 2278
SD heart left ventricle end-systolic diameter sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-systolic diameter male 175 days 10 5.6 mm 0.1 0.32 echocardiography 0.0 sham ACF 105 days 99241 2278
SD heart left ventricle end-diastolic diameter to posterior wall thickness ratio sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 8 lvedd/pw 4.8 null 0.3 0.85 echocardiography 0.0 sham ACF 28 days heart left ventricle end-diastolic dimeter to posterior wall thickness ratio 99243 2278
SD heart left ventricle interstitial bradykinin level during a period of time sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle interstitial bradykinin amount male 98 days 8 6.4 pg/hr 0.4 1.13 radioimmunoassay 0.0 sham ACF 28 days heart left ventricle interstitial bradykinin level during a period of time 99263 2278
SD heart left ventricle interstitial epinephrine level during a period of time sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle interstitial epinephrine amount male 98 days 8 3.5 pg/hr 0.3 0.85 enzyme linked immunosorbent assay 0.0 sham ACF 28 days heart left ventricle interstitial epinephrine level during a period of time 99271 2278
SD plasma angiotensin II level sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. blood angiotensin II amount male 175 days 8 34.0 pg/ml 4.0 11.31 radioimmunoassay 0.0 sham ACF 105 days 99277 2278
SD heart rate sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart pumping trait male 98 days 7 312.0 beats/min 5.0 13.23 vascular transducer tipped catheter 0.0 sham ACF 28 days 99297 2278
SD left ventricular end-diastolic blood pressure sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 4.0 mmHg 1.0 2.65 vascular transducer tipped catheter 0.0 sham ACF 28 days 99313 2278
SD left ventricular end-systolic blood pressure sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 85.0 mmHg 3.0 7.94 vascular transducer tipped catheter 0.0 sham ACF 28 days 99319 2278
SD maximum rate of negative change in left ventricular blood pressure sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 -7379.0 mmHg/s 445.0 1177.36 vascular transducer tipped catheter 0.0 sham ACF 28 days 99335 2278
SD heart left ventricle fractional shortening sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 72 days 5 41.0 % 2.0 4.47 echocardiography 0.0 sham ACF 2 days ledd/pw 99363 2278
SD body weight sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. body mass male 77 days 6 378.1 g 12.1 29.64 body weighing method 0.0 sham lad occlusion 28 days 101076 2564
SD body weight sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. body mass male 189 days 6 532.2 g 20.4 49.97 body weighing method 0.0 sham lad occlusion 140 days 101078 2564
WF/Mol body weight controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 6 190.0 g 5.0 12.25 body weighing method 0.0 sham acf 2 days 101311 2585
SD left ventricle end-systolic wall stress sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 72 days 5 50.0 g/cm2 3.0 6.71 echocardiography 0.0 sham ACF 2 days lves-ws 99395 2278
SD ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle interstitial collagen amount male 98 days 7 3.5 % 0.1 0.26 ex vivo light microscopy with histochemistry and digital image analysis 0.0 sham ACF 28 days 99407 2278
SBN/Ygl body weight sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days) Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. body mass male 16 days 8 328.0 g 5.4 15.27 body weighing method 0.0 0 n=8-15 106640 3035
HsdCpb:WU central venous pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. venous blood pressure trait male 84 days 5 1.2 mmHg 1.9 4.25 vascular indwelling catheter method vena cava 0.0 0 108780 3130
MWF/Hsd central venous pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. venous blood pressure trait male 84 days 5 2.1 mmHg 1.7 3.8 vascular indwelling catheter method vena cava 0.0 0 108781 3130
HsdCpb:WU maximum rate of positive change in left ventricular blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart left ventricular blood pressure trait male 175 days 10 9091.0 mmHg/s 299.0 945.52 vascular indwelling catheter method heart left ventricle 0.0 0 108850 3130
HsdCpb:WU maximum rate of negative change in left ventricular blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart left ventricular blood pressure trait male 175 days 10 7463.0 mmHg/s 375.0 1185.85 vascular indwelling catheter method heart left ventricle 0.0 0 108854 3130
HsdCpb:WU cardiac myocyte cross-sectional area sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. cardiomyocyte morphology trait male 84 days 5 414.0 um2 48.0 107.33 ex vivo light microscopy with histochemistry and digital image analysis heart left ventricle 0.0 0 cardiac myocyte cross-sectional area (CMO:0003840) 108901 3130
SHR-Chr 8MWF/Rkb urine albumin excretion rate sham surgical control condition (for 126 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. urine albumin amount male 168 days 9 10.8 mg/d 2.1 6.3 enzyme linked immunosorbent assay 0.0 0 109563 3148
BDIX/OrlCrl calculated liver tumorous lesion volume measurement DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (between 17 and 31 days) Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7. liver integrity trait male 0 days 12 2.41 cm3 0.74 2.56 magnetic resonance imaging liver 0.0 31 days sham surgical group POD24 sham surgical group POD24 110988 3191
BDIX/OrlCrl calculated liver tumorous lesion volume measurement DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (for 17 days) Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7. liver integrity trait male 0 days 12 0.67 cm3 0.13 0.45 magnetic resonance imaging liver 0.0 24 days sham surgical group POD17 sham surgical group POD17 110823 3191
HsdCpb:WU blood B-type natriuretic peptide level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. blood protein amount male 133 days 5 0.6 ng/ml 0.4 0.89 enzyme immunoassay 0.0 0 blood B-type natriuretic peptide level (CMO:0003868) 108885 3130
HsdCpb:WU heart rate sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart pumping trait male 175 days 10 331.0 beats/min 14.0 44.27 vascular indwelling catheter method heart 0.0 0 108838 3130
MWF/Hsd heart rate sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart pumping trait male 175 days 9 364.0 beats/min 28.0 84.0 vascular indwelling catheter method heart 0.0 0 108840 3130
MWF/Hsd mean arterial blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. arterial blood pressure trait male 175 days 9 107.0 mmHg 4.0 12.0 vascular indwelling catheter method aorta 0.0 0 108844 3130
MWF/Hsd body weight sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. body mass male 175 days 9 340.0 g 9.0 27.0 body weighing method 0.0 0 108788 3130
HsdCpb:WU water drink intake rate sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. drinking behavior trait male 175 days 10 21.0 ml/d 1.0 3.16 metabolic cage water drinking measurement method 0.0 0 108794 3130
MWF/Hsd water drink intake rate sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. drinking behavior trait male 175 days 9 22.0 ml/d 1.0 3.0 metabolic cage water drinking measurement method 0.0 0 108795 3130
HsdCpb:WU plasma potassium level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. blood potassium amount male 175 days 10 4.4 mmol/l 0.2 0.63 automated blood electrolyte analysis 0.0 0 108810 3130
BN/SsNHsd circular vessel area sham surgical control condition Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252. iliac artery morphology trait male 119 days-133 days 11 0.28 mm2 0.03 0.1 ex vivo light microscopy with digital image analysis 0.0 0 110497 3107
HsdCpb:WU kidney glomerular density sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. kidney glomerulus quantity not specified 84 days 8 12.1 /mm3 3.1 8.77 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 109644 3149
HsdCpb:WU urine total protein excretion rate sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. total urine protein amount not specified 84 days 15 8.0 mg/d 7.0 27.11 urine total protein analysis 0.0 0 109651 3149
HsdCpb:WU urine albumin excretion rate sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. urine albumin amount not specified 84 days 15 0.2 mg/d 0.0 0.0 enzyme linked immunosorbent assay 0.0 0 109658 3149
MWF/FubRkb urine albumin excretion rate sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. urine albumin amount not specified 84 days 15 58.1 mg/d 5.8 22.46 enzyme linked immunosorbent assay 0.0 0 109659 3149
MWF/FubRkb heart left ventricle interstitial fibrotic lesion area to total heart left ventricule area ratio sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. heart left ventricle integrity trait not specified 86 days 15 1.6 % 0.2 0.77 ex vivo light microscopy with histochemistry and digital image analysis heart left ventricle 0.0 0 109665 3149
BN/SsNHsd pituitary gland wet weight sham surgical control condition (between 193 and 199 days) Shull JD, et al., Mamm Genome. 2007 Sep 18;. pituitary gland mass female 252 days-266 days 10 0.01 g 0.0 0.0 post excision weight measurement pituitary gland 0 0 13099 331
COP/CrCrl pituitary gland wet weight sham surgical control condition Strecker TE, et al., Genetics 2005 Jan 31;. pituitary gland mass male 147 days 6 0.01 g 0.0 0.0 post excision weight measurement 0.0 0 69102 1122
SD mean arterial blood pressure sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. arterial blood pressure trait male 72 days 5 100.0 mmHg 2.0 4.47 vascular transducer tipped catheter 0.0 sham ACF 2 days 99299 2278
SD left ventricular end-diastolic blood pressure sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 72 days 5 5.0 mmHg 1.0 2.24 vascular transducer tipped catheter 0.0 sham ACF 2 days 99309 2278
SD maximum rate of positive change in left ventricular blood pressure sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 72 days 5 8301.0 mmHg/s 442.0 988.34 vascular transducer tipped catheter 0.0 sham ACF 2 days 99325 2278
SD maximum rate of negative change in left ventricular blood pressure sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 72 days 5 -7474.0 mmHg/s 152.0 339.88 vascular transducer tipped catheter 0.0 sham ACF 2 days 99331 2278
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 72 days 5 6.9 mm 0.2 0.45 echocardiography 0.0 sham ACF 2 days 99339 2278
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 72 days 5 7.0 mm 0.1 0.22 echocardiography 0.0 sham ACF 2 days 99341 2278
SD heart left ventricle end-systolic diameter sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-systolic diameter male 72 days 5 4.1 mm 0.2 0.45 echocardiography 0.0 sham ACF 2 days 99349 2278
SD right atrium weight sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart right atrium mass male 189 days 6 0.04 g 0.0 0.01 ex vivo method 0.0 sham lad occlusion 140 days 101118 2564
WF/Mol body weight vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 5 188.0 g 1.0 2.24 body weighing method 0.0 4 days 101303 2585
WF/Mol body weight vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 5 192.0 g 3.0 6.71 body weighing method 0.0 4 days 101317 2585
WF/Mol body weight gain vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 5 6.0 g 1.0 2.24 body weighing method 0.0 sham acf 4 days change from surgery weight 101339 2585
WKY timed urine volume sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. urine output male 238 days-252 days 7 13.9 ml/d 1.6 4.23 urine volume measurement method 0.0 lad occlusion sham 196 days 100360 2460
SD heart left ventricle weight to body weight ratio sham surgical control condition (for 2 days) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle mass male 0 days 6 g/g*103 2.2 mg/g 0.1 0.24 post excision weight measurement 1.0 sham ACF 2 days 98790 2160
SD left ventricular end-diastolic blood pressure sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 5.0 mmHg 2.0 4.9 vascular transducer tipped catheter 1.0 sham ACF 360 min 98819 2160
SD left ventricular end-diastolic blood pressure sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 2.0 mmHg 1.0 2.45 vascular transducer tipped catheter 1.0 sham ACF 720 min 98821 2160
SD left ventricular end-diastolic blood pressure sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 2.0 mmHg 1.0 2.45 vascular transducer tipped catheter 1.0 sham ACF 2 days 98823 2160
SD heart left ventricle end-diastolic diameter to posterior wall thickness ratio sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 4.4 null 0.4 0.98 HP Sonos 5500 echo ultrasound 1.0 sham ACF 360 min heart left ventricle end-diastolic diameter to posterior wall thickness ratio 98867 2160
SD heart left ventricle end-diastolic diameter to posterior wall thickness ratio sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 4.5 null 0.5 1.22 HP Sonos 5500 echo ultrasound 1.0 sham ACF 720 min heart left ventricle end-diastolic diameter to posterior wall thickness ratio 98869 2160
SD heart left ventricle end-diastolic diameter to posterior wall thickness ratio sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 4.4 null 0.4 0.98 HP Sonos 5500 echo ultrasound 1.0 sham ACF 5 days heart left ventricle end-diastolic diameter to posterior wall thickness ratio 98873 2160
SD heart left ventricle weight to body weight ratio sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle mass male 0 days 6 g/g*103 2.3 mg/g 0.1 0.24 post excision weight measurement 1.0 sham ACF 2 days 98875 2160
Crl:WI(Han) body weight sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. body mass female 87 days 6 292.0 g 13.0 31.84 body weighing method 0.0 0 102930 2782
SD adrenal gland weight sham surgical control condition (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. adrenal gland mass male 0 days 6 51.0 mg 1.63 4.0 post excision weight measurement 0.0 sham unx 13 days 101559 2602
WF/Mol systolic blood pressure vehicle control condition then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male 0 days 6 undefined 150.0 mmHg 4.0 9.8 tail cuff plethysmography 0.0 sham acf 2 days 101357 2585
WF/Mol heart left ventricle weight controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart left ventricle mass male 0 days 6 0.2 g 0.01 0.01 post excision weight measurement 0.0 sham acf 7 days 101407 2585
WKY body weight sham surgical control condition Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. body mass male 42 days-56 days 12 223.0 g 1.4 4.85 body weighing method 0.0 lad occlusion 0 days 100267 2460
WKY body weight sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. body mass male 238 days-252 days 12 566.0 g 17.0 58.89 body weighing method 0.0 lad occlusion sham 196 days 100270 2460
WKY/Cfd left ventricular end-systolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 129.7 mmHg 0.8 1.79 vascular indwelling catheter method 0.0 0 68867 1014
WKY.WKHA-(D5Rat45-D5Rat245)/Cfd left ventricular end-systolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 120.3 mmHg 2.4 5.37 vascular indwelling catheter method 0.0 0 68872 1014
WKY/Cfd maximum rate of positive change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 10672.0 mmHg/s 343.0 766.97 vascular indwelling catheter method 0.0 0 68896 1014
WKY/Cfd maximum rate of negative change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 7503.0 mmHg/s 375.0 838.53 vascular indwelling catheter method 0.0 0 68908 1014
WKY/Cfd time constant of left ventricular pressure decay sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 18.6 ms 0.74 1.65 vascular indwelling catheter method 0.0 0 "time constant of left ventricular pressure decay" 68914 1014
WKY/Cfd maximum rate of positive change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 9876.0 mmHg/s 495.0 1106.85 vascular indwelling catheter method 0.0 0 "rate of maximum positive change in left ventricular blood pressure" mmHg/s 68890 1014
SD heart left ventricle weight to body weight ratio sham surgical control condition (for 6 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle mass male 0 days 6 g/g*103 2.2 mg/g 0.1 0.24 post excision weight measurement 1.0 sham ACF 360 min 98786 2160
SD mean arterial blood pressure sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. arterial blood pressure trait male 0 days 6 86.0 mmHg 4.0 9.8 vascular transducer tipped catheter 1.0 sham ACF 2 days 98815 2160
SD heart rate sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart pumping trait male 98 days 8 260.0 beats/min 12.0 33.94 vascular transducer tipped catheter 0.0 sham ACF 28 days 99215 2278
SS/JrHsd body weight controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 235.0 g 13.0 body weighing method 0.0 0 102190 2681
SR/JrHsd single kidney wet weight controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 0.86 g 0.02 post excision weight measurement 0.0 0 102195 2681
SS/JrHsd single kidney wet weight controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 0.87 g 0.02 post excision weight measurement 0.0 0 102201 2681
SS/JrHsd single kidney wet weight controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 1.26 g 0.09 post excision weight measurement 0.0 0 102202 2681
WKY heart weight sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart mass male 266 days-280 days 5 1.27 g 0.07 0.16 post excision weight measurement 0.0 lad occlusion sham 210 days 100279 2460
WKY heart left ventricle weight sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle mass male 238 days-252 days 12 0.85 g 0.03 0.09 post excision weight measurement 0.0 lad occlusion sham 196 days 100288 2460
WKY heart left ventricle weight to tibia length ratio sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle mass male 266 days-280 days 5 0.19 g/cm 0.01 0.01 post excision weight measurement 0.0 lad occlusion sham 210 days lv/tl 100294 2460
Crl:WI(Han) plasma insulin level sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. blood insulin amount female 87 days 6 221.0 mU/l 44.2 108.27 enzyme linked immunosorbent assay 0.0 0 103761 2782
WF/Mol systolic blood pressure vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male 0 days 5 undefined 123.0 mmHg 5.0 11.18 tail cuff plethysmography 0.0 sham acf 4 days 101347 2585
WF/Mol systolic blood pressure vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male 0 days 5 undefined 160.0 mmHg 4.0 8.94 tail cuff plethysmography 0.0 sham acf 4 days 101361 2585
WF/Mol heart rate controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male 0 days 5 366.0 beats/min 14.0 31.3 tail cuff plethysmography 0.0 sham acf 4 days 101367 2585
WF/Mol heart left ventricle weight controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart left ventricle mass male 0 days 6 0.21 g 0.01 0.01 post excision weight measurement 0.0 sham acf 2 days 101399 2585
WF/Mol heart left ventricle weight vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart left ventricle mass male 0 days 5 0.21 g 0.0 0.01 post excision weight measurement 0.0 sham acf 4 days 101405 2585
SR/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91 days-119 days 6 140.8 mmol/l 1.6 3.92 flame atomic emission spectrometry 0.0 0 102249 2682
SR/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91 days-119 days 6 139.8 mmol/l 0.7 1.71 flame atomic emission spectrometry 0.0 0 102251 2682
GK heart weight to body weight ratio sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. heart mass female 87 days 6 4.0 g/kg 0.3 0.73 post excision weight measurement 0.0 0 103779 2782
SD body weight sham surgical control condition (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. body mass male 0 days 6 336.0 g 6.53 16.0 body weighing method 0.0 sham unx 13 days 101535 2602
SD left kidney wet weight sham surgical control condition (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. kidney mass male 0 days 6 1.11 g 0.02 0.06 post excision weight measurement 0.0 sham unx 13 days remnant kidney 101543 2602
WF/Mol body weight gain vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 5 23.0 g 3.0 6.71 body weighing method 0.0 sham acf 7 days change from surgery weight 101343 2585
SD heart weight to body weight ratio sham surgical control condition (for 2 days) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart mass male 0 days 6 g/g*103 3.3 g/kg 0.1 0.24 post excision weight measurement 1.0 sham ACF 2 days 98782 2160
SS/JrHsd body weight controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days) Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13. body mass female 112 days 6 281.5 g 4.1 10.04 body weighing method 0.0 sham ovx 63 days 102340 2686
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 7.1 mm 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 sham ACF 2 days 98847 2160
SD heart left ventricle end-diastolic diameter sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 7.1 mm 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 sham ACF 5 days 98849 2160
SD heart left ventricle end-diastolic posterior wall thickness sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle posterior wall thickness male 0 days 6 1.6 mm 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 sham ACF 360 min 98859 2160
SD heart left ventricle end-diastolic posterior wall thickness sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle posterior wall thickness male 0 days 6 1.6 mm 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 sham ACF 2 days 98863 2160
SD maximum rate of positive change in left ventricular blood pressure sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 7985.0 mmHg/s 200.0 489.9 vascular transducer tipped catheter 1.0 sham ACF 2 days 98889 2160
WF/Mol heart left ventricle weight vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart left ventricle mass male 0 days 5 0.22 g 0.01 0.02 post excision weight measurement 0.0 sham acf 4 days 101391 2585
WF/Mol heart left ventricle weight vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart left ventricle mass male 0 days 5 0.21 g 0.01 0.01 post excision weight measurement 0.0 sham acf 7 days 101395 2585
SD ejection fraction sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. cardiac output trait male 0 days 6 65.0 % 2.0 4.9 HP Sonos 5500 echo ultrasound 1.0 sham ACF 360 min 98879 2160
WF/Mol heart rate controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male 0 days 6 407.0 beats/min 16.0 39.19 tail cuff plethysmography 0.0 sham acf 7 days 101385 2585
SR/JrHsd both kidneys wet weight controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days) Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13. kidney mass female 112 days 6 1.57 g 0.04 0.1 post excision weight measurement 0.0 sham ovx 63 days 102349 2686
SR/JrHsd uterus weight controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days) Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13. uterus mass female 112 days 6 0.41 g 0.02 0.05 post excision weight measurement 0.0 sham ovx 63 days 102355 2686
Crl:WI(WU) plasma angiotensin I converting enzyme activity level sham surgical control condition Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. angiotensin I-converting enzyme activity male 91 days 14 62.2 nmol/min/mL 4.2 15.71 radioactivity measurement method 0.0 sham surgery 35 days 100029 2398
SR/JrHsd body weight controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days) Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13. body mass female 112 days 6 253.5 g 4.9 12.0 body weighing method 0.0 sham ovx 63 days 102343 2686
SD systolic blood pressure sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. arterial blood pressure trait male 77 days 6 undefined 134.0 mmHg 2.0 4.9 tail cuff plethysmography 0.0 sham lad occlusion 28 days 101088 2564
SD heart left ventricle weight sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart left ventricle mass male 77 days 6 0.6 g 0.02 0.05 ex vivo method 0.0 sham lad occlusion 28 days 101092 2564
SD heart left ventricle weight sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart left ventricle mass male 189 days 6 0.76 g 0.03 0.07 ex vivo method 0.0 sham lad occlusion 140 days 101094 2564
SD heart right ventricle weight to body weight ratio sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart right ventricle mass male 77 days 6 0.59 mg/g 0.01 0.02 ex vivo method 0.0 sham lad occlusion 28 days 101104 2564
SD left atrium weight sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart left atrium mass male 77 days 6 0.03 g 0.0 0.0 ex vivo method 0.0 sham lad occlusion 28 days 101108 2564
SD heart left atrium weight to body weight ratio sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart left atrium mass male 77 days 6 0.07 mg/g 0.0 0.01 ex vivo method 0.0 sham lad occlusion 28 days law/bw 101112 2564
SD heart right atrium weight to body weight ratio sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart right atrium mass male 77 days 6 0.1 mg/g 0.0 0.01 ex vivo method 0.0 sham lad occlusion 28 days raw/bw 101120 2564
SD heart right atrium weight to body weight ratio sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart right atrium mass male 189 days 6 0.08 mg/g 0.01 0.01 ex vivo method 0.0 sham lad occlusion 140 days raw/bw 101122 2564
SD heart septum weight sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart septum morphology trait male 77 days 6 0.23 g 0.01 0.02 ex vivo method 0.0 sham lad occlusion 28 days septum 101124 2564
WF/Mol body weight vehicle control condition then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 6 200.0 g 2.0 4.9 body weighing method 0.0 2 days 101313 2585
WF/Mol body weight gain vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 5 18.0 g 1.0 2.24 body weighing method 0.0 4 days change from surgery weight 101325 2585
SD maximum rate of positive change in left ventricular blood pressure sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 8 8031.0 mmHg/s 440.0 1244.51 vascular transducer tipped catheter 0.0 sham ACF 28 days 99227 2278
SD maximum rate of negative change in left ventricular blood pressure sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 175 days 10 -5401.0 mmHg/s 358.0 1132.1 vascular transducer tipped catheter 0.0 sham ACF 105 days 99233 2278
SD heart left ventricle end-diastolic diameter to posterior wall thickness ratio sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 175 days 10 lvedd/pw 5.9 null 0.3 0.95 echocardiography 0.0 sham ACF 105 days heart left ventricle end-diastolic dimeter to posterior wall thickness ratio 99245 2278
SD left ventricle end-systolic wall stress sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 8 67.0 g/cm2 13.0 36.77 echocardiography 0.0 sham ACF 28 days 99251 2278
SD heart left ventricle fractional shortening sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 175 days 10 40.0 % 1.0 3.16 echocardiography 0.0 sham ACF 105 days 99257 2278
SD heart rate sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart pumping trait male 98 days 7 321.0 beats/min 7.0 18.52 vascular transducer tipped catheter 0.0 sham ACF 28 days 99295 2278
SD mean arterial blood pressure sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. arterial blood pressure trait male 98 days 7 107.0 mmHg 3.0 7.94 vascular transducer tipped catheter 0.0 sham ACF 28 days 99303 2278
SD heart left ventricle end-systolic diameter sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-systolic diameter male 98 days 7 4.7 mm 0.2 0.53 echocardiography 0.0 sham ACF 28 days 99351 2278
SD heart left ventricle end-diastolic diameter to posterior wall thickness ratio sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 7 lvedd/pw 4.2 null 0.2 0.53 echocardiography 0.0 sham ACF 28 days heart left ventricle end-diastolic diameter to posterior wall thickness ratio 99359 2278
WF/Mol heart right ventricle weight controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart right ventricle mass male 0 days 6 0.05 g 0.0 0.0 post excision weight measurement 0.0 sham acf 2 days 101421 2585
WF/Mol heart right ventricle weight controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart right ventricle mass male 0 days 6 0.05 g 0.0 0.0 post excision weight measurement 0.0 sham acf 4 days 101425 2585
WF/Mol heart right ventricle weight vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart right ventricle mass male 0 days 5 0.05 g 0.0 0.0 post excision weight measurement 0.0 sham acf 4 days 101427 2585
MW plasma renin activity level sham surgical control condition (for 28 days) Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. renin activity male 0 days 7 9.1 ng/ml/h 0.5 1.32 radioimmunoassay 0.0 sham surgery 28 days 101043 2561
WKY plasma creatinine level sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. blood creatinine amount male 238 days-252 days 6 0.41 mg/dl 0.03 0.07 plasma creatinine analysis 0.0 lad occlusion sham 196 days 100363 2460
SD left ventricle end-systolic wall stress sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 65.0 g/cm2 5.0 13.23 echocardiography 0.0 sham ACF 28 days 99399 2278
SD ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle interstitial collagen amount male 72 days 5 4.0 % 0.3 0.67 ex vivo light microscopy with histochemistry and digital image analysis 0.0 sham ACF 2 days 99405 2278
SBH/Ygl body weight sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days) Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. body mass male 16 days 8 359.0 g 3.1 8.77 body weighing method 0.0 0 n=8-15 106643 3035
SHR-Chr 8MWF/Rkb right kidney wet weight sham surgical control condition (for 126 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. kidney mass male 168 days 9 1.16 g 0.04 0.12 post excision weight measurement kidney 0.0 0 109554 3148
SHR/FubRkb urine albumin excretion rate sham surgical control condition (for 42 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. urine albumin amount male 168 days 9 1.3 mg/d 0.3 0.9 enzyme linked immunosorbent assay 0.0 0 109561 3148
HsdCpb:WU left ventricular end-diastolic blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart left ventricular blood pressure trait male 84 days 5 5.3 mmHg 2.4 5.37 vascular indwelling catheter method heart left ventricle 0.0 0 108776 3130
MWF/Hsd maximum rate of positive change in left ventricular blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart left ventricular blood pressure trait male 175 days 9 8993.0 mmHg/s 318.0 954.0 vascular indwelling catheter method heart left ventricle 0.0 0 108852 3130
HsdCpb:WU systemic vascular resistance sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. arterial blood pressure trait male 168 days 10 0.71 mmHg/ml/min 0.07 0.22 vascular indwelling catheter method 0.0 0 108890 3130
SHR/FubRkb plasma cystatin C level sham surgical control condition (for 126 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. blood cystatin C amount male 168 days 9 0.05 mg/l 0.0 0.01 automated plasma protein analysis 0.0 0 109566 3148
SHR-Chr 8MWF/Rkb plasma cystatin C level sham surgical control condition (for 126 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. blood cystatin C amount male 168 days 9 0.05 mg/l 0.0 0.01 automated plasma protein analysis 0.0 0 109568 3148
HsdCpb:WU artery tunica media width to artery inner diameter ratio sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. aorta morphology trait male 168 days 10 0.23 null 0.03 0.09 ex vivo light microscopy with histochemistry and digital image analysis aorta wall 0.0 0 108886 3130
MWF/Hsd artery tunica media width to artery inner diameter ratio sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. aorta morphology trait male 168 days 9 0.25 null 0.2 0.6 ex vivo light microscopy with histochemistry and digital image analysis aorta wall 0.0 0 108888 3130
BDIX/OrlCrl subsequent liver tumorous lesion volume to precedent liver tumorous lesion volume ratio DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (for 17 days) Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7. liver integrity trait male 0 days 12 518.0 % 117.0 405.3 magnetic resonance imaging liver 0.0 0 17-24 days after tumor cell injection sham surgical group POD17 111000 3191
BDIX/OrlCrl subsequent liver tumorous lesion volume to precedent liver tumorous lesion volume ratio DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (for 31 days) Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7. liver integrity trait male 0 days 12 2112.0 % 618.0 2140.81 magnetic resonance imaging liver 0.0 0 17-31 days after tumor cell injection sham surgical group POD24 111001 3191
SHR-Chr 6MWF/Rkb urine albumin excretion rate sham surgical control condition Schulz A, etal., Physiol Genomics. 2010 Jun. urine albumin amount male 84 days 10 1.3 mg/d 0.3 0.95 enzyme linked immunosorbent assay 0.0 0 108126 3116
HsdCpb:WU food intake rate sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. eating behavior trait male 175 days 10 11.0 g/d 2.0 6.32 food intake measuring method 0.0 0 108790 3130
MWF/Hsd hematocrit sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. erythrocyte quantity male 175 days 9 45.0 % 0.8 2.4 hematocrit analysis 0.0 0 108804 3130
MWF/Hsd plasma potassium level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. blood potassium amount male 175 days 9 4.5 mmol/l 0.1 0.3 automated blood electrolyte analysis 0.0 0 108812 3130
HsdCpb:WU right kidney wet weight to body weight ratio sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. kidney mass male 175 days 10 3.7 mg/g 0.1 0.32 post excision weight measurement 0.0 0 108830 3130
HsdCpb:WU left ventricular systolic blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart left ventricular blood pressure trait male 175 days 10 128.0 mmHg 4.0 12.65 vascular indwelling catheter method heart left ventricle 0.0 0 108846 3130
SHRSP/A3NCrl partial pressure of brain white matter oxygen sham surgical control condition then standard diet Weaver J, etal., J Cereb Blood Flow Metab. 2014 May;34(5):890-6. doi: 10.1038/jcbfm.2014.35. Epub 2014 Feb 19. brain oxygen amount male 98 days 8 18.0 mmHg 3.4 9.62 electron paramagnetic resonance oximetry white matter 40.0 0 5 scans x 40 seconds partial pressure of brain white matter oxygen (CMO:0003626) 107322 3080
SHRSP/A3NCrl partial pressure of brain white matter oxygen sham surgical control condition then standard diet Weaver J, etal., J Cereb Blood Flow Metab. 2014 May;34(5):890-6. doi: 10.1038/jcbfm.2014.35. Epub 2014 Feb 19. brain oxygen amount male 105 days 8 16.8 mmHg 3.7 10.47 electron paramagnetic resonance oximetry white matter 40.0 0 5 scans x 40 seconds partial pressure of brain white matter oxygen (CMO:0003626) 107323 3080
ACI/SegHsd pituitary gland wet weight sham surgical control condition (between 193 and 199 days) Shull JD, et al., Mamm Genome. 2007 Sep 18;. pituitary gland mass female 252 days-266 days 10 0.01 g 0.0 0.0 post excision weight measurement pituitary gland 0 0 13090 331
WKY heart left ventricle fractional shortening sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-diastolic diameter male 238 days-252 days 12 41.1 % 3.0 10.39 echocardiography 0.0 lad occlusion sham 196 days 100348 2460
SR/JrHsd body weight controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 232.0 g 4.1 body weighing method 0.0 0 102184 2681
SD heart left ventricle weight to body weight ratio sham surgical control condition (for 2 days) then metoprolol succinate (100 mg/kg/d) (for 2 days) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle mass male 0 days 6 g/g*103 2.5 mg/g 0.1 0.24 post excision weight measurement 1.0 sham ACF 2 days 98877 2160
WKY artery tunica media width to artery inner diameter ratio sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. kidney blood vessel morphology trait male 238 days-252 days 11 1.89 null 0.12 0.4 ex vivo light microscopy with histochemistry and digital image analysis 0.0 lad occlusion sham 196 days 100386 2460
Crl:WI(Han) blood glucose level sham surgical control condition (for 24 days) then fasting (for 12 hours) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. blood glucose amount female 87 days 6 105.0 mg/dl 3.0 7.35 machine read blood glucose test strip 0.0 0 103757 2782
Crl:WI(Han) heart weight to body weight ratio sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. heart mass female 87 days 6 3.2 g/kg 0.1 0.24 post excision weight measurement 0.0 0 103777 2782
SD plasma renin activity level sham surgical control condition (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. renin activity male 0 days 6 3.1 ng/ml/h 0.29 0.7 radioimmunoassay 0.0 sham unx 13 days 101563 2602
WF/Mol body weight vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 6 201.0 g 3.0 7.35 body weighing method 0.0 7 days 101321 2585
WF/Mol body weight gain vehicle control condition then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 6 -6.0 g 1.0 2.45 body weighing method 0.0 sham acf 2 days change from surgery weight 101335 2585
SD left ventricular end-diastolic blood pressure sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 72 days 5 6.0 mmHg 1.0 2.24 vascular transducer tipped catheter 0.0 sham ACF 2 days 99307 2278
SD maximum rate of negative change in left ventricular blood pressure sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 72 days 5 -8474.0 mmHg/s 123.0 275.04 vascular transducer tipped catheter 0.0 sham ACF 2 days 99333 2278
SD heart left ventricle end-diastolic diameter to posterior wall thickness ratio sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 72 days 5 lvedd/pw 4.6 null 0.2 0.45 echocardiography 0.0 sham ACF 2 days heart left ventricle end-diastolic diameter to posterior wall thickness ratio 99355 2278
WKY diastolic blood pressure sham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. arterial blood pressure trait male 266 days-280 days 5 10 min mean continuous mean 63.3 mmHg 6.9 15.43 vascular transducer tipped catheter 0.0 lad occlusion sham 210 days 100318 2460
WKY left ventricular end-diastolic blood pressure sham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricular blood pressure trait male 266 days-280 days 5 10 min mean continuous mean 5.5 mmHg 2.4 5.37 vascular transducer tipped catheter 0.0 lad occlusion sham 210 days 100324 2460
BN/SsNHsd binary logarithm of pituitary gland wet weight sham surgical control condition (between 193 and 199 days) Shull JD, et al., Mamm Genome. 2007 Sep 18;. pituitary gland mass female 252 days-266 days 10 2.89 null 0.08 0.24 post excision weight measurement pituitary gland 0 0 logarithm of pituitary wet weight 65769 331
WKY.WKHA-(D5Rat45-D5Rat245)/Cfd left ventricular end-diastolic blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 0.22 mmHg 0.25 0.56 vascular indwelling catheter method 0.0 0 68859 1014
WKY.WKHA-(D5Rat45-D5Rat245)/Cfd maximum rate of negative change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait male 84 days-154 days 5 7570.0 mmHg/s 476.0 1064.37 vascular indwelling catheter method 0.0 0 68906 1014
WKY.WKHA-(D5Rat45-D5Rat245)/Cfd maximum rate of negative change in left ventricular blood pressure sham surgical control condition Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12. heart left ventricular blood pressure trait female 84 days-154 days 5 6589.0 mmHg/s 296.0 661.88 vascular indwelling catheter method 0.0 0 68912 1014
SD heart rate sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart pumping trait male 0 days 6 365.0 beats/min 15.0 36.74 HP Sonos 5500 echo ultrasound 1.0 sham ACF 5 days 98800 2160
WKY heart weight to tibia length ratio sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart mass male 266 days-280 days 5 0.28 g/cm 0.01 0.02 post excision weight measurement 0.0 lad occlusion sham 210 days 100282 2460
WKY tibia length sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. tibia length male 266 days-280 days 5 4.3 cm 0.12 0.27 post excision length measurement 0.0 lad occlusion sham 210 days 100285 2460
WKY lung wet weight sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. lung mass male 238 days-252 days 12 1.78 g 0.05 0.16 post excision weight measurement 0.0 lad occlusion sham 196 days 100297 2460
WKY ejection fraction sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. cardiac output trait male 266 days-280 days 5 86.8 % 1.5 3.35 echocardiography 0.0 lad occlusion sham 210 days 100300 2460
WF/Mol heart rate controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male 0 days 5 424.0 beats/min 10.0 22.36 tail cuff plethysmography 0.0 sham acf 2 days 101377 2585
WKY timed urine volume sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. urine output male 238 days-252 days 7 13.9 ml/d 1.6 4.23 urine volume measurement method 0.0 lad occlusion sham 196 days 100374 2460
WKY kidney fibrotic lesion area to total kidney area ratio sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. kidney integrity trait male 238 days-252 days 11 0.91 % 0.03 0.1 ex vivo light microscopy with histochemistry and digital image analysis 0.0 lad occlusion sham 196 days 100383 2460
WF/Mol heart left ventricle weight controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart left ventricle mass male 0 days 5 0.2 g 0.0 0.0 post excision weight measurement 0.0 sham acf 7 days 101393 2585
SD left ventricular end-diastolic blood pressure sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricular blood pressure trait male 0 days 6 3.0 mmHg 1.0 2.45 vascular transducer tipped catheter 1.0 sham ACF 2 days 98829 2160
SD ejection fraction sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. cardiac output trait male 0 days 6 64.0 % 3.0 7.35 HP Sonos 5500 echo ultrasound 1.0 sham ACF 5 days 98885 2160
GK blood glucose level sham surgical control condition (for 24 days) then fasting (for 12 hours) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. blood glucose amount female 87 days 6 172.0 mg/dl 9.0 22.05 machine read blood glucose test strip 0.0 0 103759 2782
Crl:WI(Han) plasma estradiol level sham surgical control condition (for 24 days) Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31. blood estradiol amount female 87 days 6 48.6 pg/ml 9.2 22.54 enzyme linked immunosorbent assay 0.0 0 103773 2782
SD urine total protein excretion rate sham surgical control condition (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. total urine protein amount male 0 days 6 10.0 mg/d 0.82 2.0 urine protein analysis 0.0 sham unx 13 days 101551 2602
SD plasma aldosterone level sham surgical control condition (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. blood aldosterone amount male 0 days 6 50.0 pg/ml 4.9 12.0 plasma aldosterone analysis 0.0 sham unx 13 days 101555 2602
SD body weight sham surgical control condition (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. body mass male 0 days 6 347.0 g 7.35 18.0 body weighing method 0.0 sham unx 28 days 101571 2602
SD change in body weight sham surgical control condition (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. body mass male 0 days 6 99.0 g 6.53 16.0 body weighing method 0.0 sham unx 28 days change from surgery weight 101575 2602
SD heart wet weight sham surgical control condition (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. heart mass male 0 days 6 1.03 g 0.02 0.05 post excision weight measurement 0.0 sham unx 28 days 101587 2602
SR/Hsd plasma osmolality controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 298.6 umol/g 3.8 9.31 osmometry 0.0 0 p osmolality mosm/kg 102257 2682
SS/Hsd plasma osmolality controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 301.4 umol/g 4.2 10.29 osmometry 0.0 0 p osmolality mosm/kg 102261 2682
WF/Mol systolic blood pressure controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male 0 days 5 undefined 129.0 mmHg 6.0 13.42 tail cuff plethysmography 0.0 sham acf 7 days 101349 2585
WF/Mol systolic blood pressure vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male 0 days 5 undefined 130.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 sham acf 7 days 101351 2585
SD heart left ventricle end-diastolic diameter to posterior wall thickness ratio sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 72 days 5 lvedd/pw 4.6 null 0.3 0.67 echocardiography 0.0 sham ACF 2 days heart left ventricle end-diastolic diameter to posterior wall thickness ratio 99357 2278
WF/Mol heart left ventricle weight vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart right ventricle mass male 0 days 5 0.06 g 0.0 0.0 post excision weight measurement 0.0 sham acf 4 days 101413 2585
WF/Mol heart right ventricle weight controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart right ventricle mass male 0 days 5 0.06 g 0.0 0.0 post excision weight measurement 0.0 sham acf 7 days 101415 2585
WF/Mol heart right ventricle weight vehicle control condition then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart right ventricle mass male 0 days 6 0.05 g 0.0 0.0 post excision weight measurement 0.0 sham acf 2 days 101423 2585
WF/Mol heart right ventricle weight controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart right ventricle mass male 0 days 6 0.05 g 0.0 0.0 post excision weight measurement 0.0 sham acf 7 days 101429 2585
SD heart left ventricle end-systolic diameter sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-systolic diameter male 0 days 6 3.8 mm 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 sham ACF 720 min 98853 2160
SD heart right ventricle weight to body weight ratio sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart right ventricle mass male 175 days 10 0.5 mg/g 0.1 0.32 post excision weight measurement 0.0 sham ACF 105 days 99209 2278
SD lung weight sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. lung mass male 175 days 10 1.97 g 0.06 0.19 post excision weight measurement 0.0 sham ACF 105 days 99213 2278
SD mean arterial blood pressure sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. arterial blood pressure trait male 175 days 10 95.0 mmHg 4.0 12.65 vascular transducer tipped catheter 0.0 sham ACF 105 days 99221 2278
SD left ventricular end-diastolic blood pressure sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 175 days 10 5.0 mmHg 1.0 3.16 vascular transducer tipped catheter 0.0 sham ACF 105 days 99225 2278
WF/Mol body weight gain controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. body mass male 0 days 6 -5.0 g 2.0 4.9 body weighing method 0.0 sham acf 2 days change from surgery weight 101333 2585
SD left ventricle end-diastolic wall stress sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 4.0 g/cm2 1.0 2.65 echocardiography 0.0 sham ACF 28 days 99393 2278
SD heart left ventricle interstitial bradykinin level during a period of time sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle interstitial bradykinin amount male 175 days 8 7.4 pg/hr 1.4 3.96 radioimmunoassay 0.0 sham ACF 105 days heart left ventricle interstitial bradykinin level during a period of time 99265 2278
SD heart left ventricle interstitial norepinephrine level during a period of time sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle interstitial norepinephrine amount male 175 days 8 5.9 pg/hr 0.4 1.13 enzyme linked immunosorbent assay 0.0 sham ACF 105 days heart left ventricle interstitial bradykinin level during a period of time 99269 2278
SD plasma bradykinin level sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. blood bradykinin amount male 175 days 8 17.0 pg/ml 2.0 5.66 radioimmunoassay 0.0 sham ACF 105 days 99281 2278
SD plasma epinephrine level sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. blood epinephrine amount male 175 days 8 75.0 pg/ml 6.0 16.97 enzyme linked immunosorbent assay 0.0 sham ACF 105 days 99289 2278
SD mean arterial blood pressure sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. arterial blood pressure trait male 98 days 7 106.0 mmHg 5.0 13.23 vascular transducer tipped catheter 0.0 sham ACF 28 days 99305 2278
SD left ventricular end-diastolic blood pressure sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricular blood pressure trait male 98 days 7 4.2 mmHg 0.0 0.0 vascular transducer tipped catheter 0.0 sham ACF 28 days 99311 2278
SD heart weight sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart mass male 77 days 6 1.13 g 0.03 0.07 ex vivo method 0.0 sham lad occlusion 28 days 101080 2564
SD heart weight sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart mass male 189 days 6 1.41 g 0.06 0.15 ex vivo method 0.0 sham lad occlusion 140 days 101082 2564
SD heart weight to body weight ratio sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart mass male 77 days 6 2.92 g/kg 0.04 0.1 ex vivo method 0.0 sham lad occlusion 28 days 101084 2564
SD systolic blood pressure sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. arterial blood pressure trait male 189 days 6 undefined 144.0 mmHg 2.0 4.9 tail cuff plethysmography 0.0 sham lad occlusion 140 days 101090 2564
SD heart left ventricle weight to body weight ratio sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart left ventricle mass male 189 days 6 1.44 mg/g 0.02 0.05 ex vivo method 0.0 sham lad occlusion 140 days 101098 2564
SD heart right ventricle weight to body weight ratio sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. heart right ventricle mass male 189 days 6 0.51 mg/g 0.01 0.02 ex vivo method 0.0 sham lad occlusion 140 days 101106 2564
WKY heart left ventricle end-systolic diameter sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-systolic diameter male 266 days-280 days 5 3.8 mm 0.3 0.67 echocardiography 0.0 lad occlusion sham 210 days 100309 2460
WKY serum sodium level sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. blood sodium amount male 266 days-280 days 5 157.7 mmol/l 6.4 14.31 automated serum sodium test 0.0 lad occlusion sham 210 days 100330 2460
WKY heart left ventricle end-diastolic diameter sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-diastolic diameter male 238 days-252 days 12 8.3 mm 0.2 0.69 echocardiography 0.0 lad occlusion sham 196 days 100339 2460
WKY E/A wave ratio sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. blood flow trait male 238 days-252 days 12 1.39 null 0.15 0.52 echocardiography 0.0 lad occlusion sham 196 days e/a wave 100354 2460
WKY right kidney wet weight sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. kidney mass male 238 days-252 days 12 1.38 g 0.07 0.24 post excision weight measurement 0.0 lad occlusion sham 196 days 100357 2460
MW urine sodium excretion rate sham surgical control condition (for 28 days) Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. urine sodium amount male 0 days 7 1.28 mEq/d 0.07 0.19 flame photometry 0.0 sham surgery 28 days 101047 2561
SD body weight sham surgical control condition (for 6 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. body mass male 0 days 6 291.0 g 10.0 24.49 body weighing method 1.0 sham ACF 360 min 98756 2160
SBN/Ygl both kidneys wet weight to body weight ratio sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days) Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. kidney mass male 16 days 8 2.4 g/kg 0.03 0.08 post excision weight measurement 0.0 0 n=8-15 106646 3035
SBH/Ygl both kidneys wet weight to body weight ratio sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days) Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. kidney mass male 16 days 8 2.6 g/kg 0.07 0.2 post excision weight measurement 0.0 0 n=8-15 106649 3035
HsdCpb:WU left ventricular systolic blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart left ventricular blood pressure trait male 84 days 5 117.0 mmHg 5.0 11.18 vascular indwelling catheter method heart left ventricle 0.0 0 108774 3130
HsdCpb:WU heart rate sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart pumping trait male 84 days 5 359.0 beats/min 18.0 40.25 vascular indwelling catheter method heart 0.0 0 108778 3130
MWF/Hsd maximum rate of negative change in left ventricular blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart left ventricular blood pressure trait male 175 days 9 6199.0 mmHg/s 513.0 1539.0 vascular indwelling catheter method heart left ventricle 0.0 0 108856 3130
HsdCpb:WU renal blood flow rate to kidney weight ratio sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. arterial blood pressure trait male 175 days 10 7.1 ml/min/g 0.8 2.53 flowmetry renal artery 0.0 0 108858 3130
SHR-Chr 8MWF/Rkb right kidney wet weight to body weight ratio sham surgical control condition (for 126 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. kidney mass male 168 days 9 3.36 mg/g 0.08 0.24 post excision weight measurement kidney 0.0 0 109558 3148
SHR/FubRkb urine albumin excretion rate sham surgical control condition (for 42 days) Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22. urine albumin amount male 84 days 9 0.4 mg/d 0.1 0.3 enzyme linked immunosorbent assay 0.0 0 109562 3148
MWF/Hsd heart rate sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart pumping trait male 84 days 5 364.0 beats/min 14.0 31.3 vascular indwelling catheter method heart 0.0 0 108779 3130
BDIX/OrlCrl increase in liver tumorous lesion volume between two points in time DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (for 17 days) Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7. liver integrity trait male 0 days 12 0.56 cm3 0.13 0.45 magnetic resonance imaging liver 0.0 0 17-24 days after tumor cell injection sham surgical group POD17 110992 3191
MWF/Hsd left ventricular systolic blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. heart left ventricular blood pressure trait male 84 days 5 131.0 mmHg 3.0 6.71 vascular indwelling catheter method heart left ventricle 0.0 0 108775 3130
BDIX/OrlCrl increase in liver tumorous lesion volume between two points in time DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (between 17 and 31 days) Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7. liver integrity trait male 0 days 12 2.3 cm3 0.74 2.56 magnetic resonance imaging liver 0.0 0 17-31 days after tumor cell injection sham surgical group POD24 110996 3191
GK/MolTac serum amylase activity level sham surgical control condition (for 126 days) then pantoprazole (100 umol/kg) (for 112 days) and sodium bicarbonate (8.5 %) (for 112 days) Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. blood glucose amount male 252 days 9 2164.0 U/l 29.0 87.0 automated serum analysis 0.0 91 days 110761 3183
GK/MolTac serum amylase activity level sham surgical control condition (for 126 days) then sodium bicarbonate (8.4 %) (for 112 days) Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. blood glucose amount male 252 days 9 2265.0 U/l 40.0 120.0 automated serum analysis 0.0 105 days 110763 3183
HsdCpb:WU mean arterial blood pressure sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. arterial blood pressure trait male 175 days 10 94.0 mmHg 3.0 9.49 vascular indwelling catheter method aorta 0.0 0 108842 3130
MWF/FubRkb urine albumin excretion rate sham surgical control condition Schulz A, etal., Physiol Genomics. 2010 Jun. urine albumin amount male 168 days 10 108.7 mg/d 12.3 38.9 enzyme linked immunosorbent assay 0.0 0 108124 3116
HsdCpb:WU timed urine volume sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. urine output male 175 days 10 15.0 ml/d 2.0 6.32 metabolic cage urine volume measurement method 0.0 0 108798 3130
MWF/Hsd plasma sodium level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. blood sodium amount male 175 days 9 137.0 mmol/l 0.0 0.0 automated blood electrolyte analysis 0.0 0 108808 3130
MWF/Hsd urine potassium level sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. urine potassium amount male 175 days 9 153.0 mmol/l 9.0 27.0 urine potassium analysis 0.0 0 108824 3130
MWF/Hsd right kidney wet weight to body weight ratio sham surgical control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. kidney mass male 175 days 9 3.3 mg/g 0.1 0.3 post excision weight measurement 0.0 0 108832 3130
SHRSP/A3NCrl partial pressure of brain white matter oxygen sham surgical control condition then standard diet Weaver J, etal., J Cereb Blood Flow Metab. 2014 May;34(5):890-6. doi: 10.1038/jcbfm.2014.35. Epub 2014 Feb 19. brain oxygen amount male 91 days 8 19.7 mmHg 3.4 9.62 electron paramagnetic resonance oximetry white matter 40.0 0 5 scans x 40 seconds