F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) and 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
male |
0 days
| 5 |
25.7 |
pg/ml |
2.33 |
5.2 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67444 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
male |
0 days
| 5 |
12.4 |
pg/ml |
1.12 |
2.51 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
|
67436 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
4.76 |
cm3 x 10000 |
|
0.4 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
|
67791 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
male |
0 days
| 5 |
0.85 |
ng/ml |
0.03 |
0.07 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67443 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
ovariectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
19.0 |
% |
|
4.2 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67454 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
liver tumorous lesion number to liver volume ratio |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
11630.0 |
/cm3 |
|
890.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
Add "liver tumorous lesion number to liver volume ratio" (new term) as child of "calculated liver tumorous lesion number" (new term). |
67449 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
ovariectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
female |
0 days
| 5 |
0.4 |
ng/ml |
0.01 |
0.02 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67451 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) and testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
female |
0 days
| 5 |
5.0 |
pg/ml |
0.36 |
0.81 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67456 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
69.0 |
% |
|
9.8 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67458 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
liver tumorous lesion diameter measurement |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
4.19 |
mm |
|
1.3 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
224 |
days |
intraperitoneal |
|
67460 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
liver tumorous lesion number to liver volume ratio |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
3840.0 |
/cm3 |
|
1450.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
Add "liver tumorous lesion number to liver volume ratio" (new term) as child of "calculated liver tumorous lesion number" (new term). |
67437 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
male |
0 days
| 5 |
8.4 |
pg/ml |
0.9 |
2.01 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67440 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
male |
0 days
| 5 |
2.0 |
ng/ml |
0.22 |
0.5 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
|
67435 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions |
ovariectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
0.39 |
cm3 x 10000 |
|
0.15 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67795 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
liver tumorous lesion number |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
38.6 |
null |
|
12.06 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
224 |
days |
intraperitoneal |
per liver |
67459 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
0.47 |
cm3 x 10000 |
|
0.13 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67792 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
male |
0 days
| 5 |
0.95 |
ng/ml |
0.09 |
0.21 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67439 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
liver tumorous lesion number to liver volume ratio |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
9420.0 |
/cm3 |
|
990.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
Add "liver tumorous lesion number to liver volume ratio" (new term) as child of "calculated liver tumorous lesion number" (new term). |
67441 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
liver tumorous lesion number to liver volume ratio |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
16820.0 |
/cm3 |
|
5100.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
Add |
67445 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
59.0 |
% |
|
9.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
|
67438 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
liver tumorous lesion number to liver volume ratio |
ovariectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
12820.0 |
/cm3 |
|
2800.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
Add "liver tumorous lesion number to liver volume ratio" (new term) as child of "calculated liver tumorous lesion number" (new term). |
67453 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
female |
0 days
| 5 |
0.42 |
ng/ml |
0.01 |
0.02 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67455 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
12.14 |
% |
|
1.45 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
pcna index |
68105 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
0.18 |
cm3 x 10000 |
|
0.11 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67793 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
10.0 |
% |
|
4.1 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
|
67450 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
ovariectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
female |
0 days
| 5 |
13.5 |
pg/ml |
1.65 |
3.7 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67452 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
3.9 |
cm3 x 10000 |
|
0.74 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67796 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
6.42 |
% |
|
0.99 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
pcna index |
68106 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
33.0 |
% |
|
8.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67442 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
female |
0 days
| 5 |
0.44 |
ng/ml |
0.03 |
0.07 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
|
67447 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
3.55 |
% |
|
0.98 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
pcna index |
68107 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
ovariectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
10.67 |
% |
|
1.4 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
pcna index |
68109 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
19.0 |
% |
|
5.4 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67446 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
female |
0 days
| 5 |
25.2 |
pg/ml |
1.88 |
4.21 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
|
67448 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
liver tumorous lesion number to liver volume ratio |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
7380.0 |
/cm3 |
|
920.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
Add |
67457 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
0.16 |
cm3 x 10000 |
|
0.09 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
|
67794 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
2.76 |
% |
|
1.1 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
pcna index |
68108 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
15.33 |
% |
|
0.74 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
pcna index |
68110 |
655 |