Phenominer Database Results (12 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Record ID Study ID
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 2 0.0 umol/l 0.0 0.0 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62777 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 3 0.01 umol/l 0.0 0.01 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62773 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 3 -8.03 null 0.16 0.27 wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter 63096 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 2 0.65 g/mg 0.02 0.03 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63169 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 2 -6.56 null 0.14 0.2 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62855 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 2 2.93 E-7mole 0.91 1.28 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63032 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 2 -7.13 null 0.12 0.17 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62851 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 2 26.5 % 13.5 19.09 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62632 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 3 0.58 g/mg 0.23 0.4 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63165 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 2 95.5 % 4.5 6.36 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62628 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 2 -8.43 null 0.27 0.38 wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter 63100 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 2 0.77 E-7mole 0.21 0.3 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63028 528