Phenominer Database Results (86 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Record ID Study ID
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi heart left ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart left ventricle mass female 70 days-84 days 3 0.37 g 0.01 0.02 digital scale post excision weight measurement 0 63773 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi heart right ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart right ventricle mass female 70 days-84 days 3 0.1 g 0.01 0.01 digital scale post excision weight measurement 0 63311 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data body mass male 70 days-84 days 7 274.57 g 3.98 10.52 whole body digital scale 0 63625 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 2 -7.13 null 0.12 0.17 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62851 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi plasma creatinine level controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) PhysGen Biochemistry data blood creatinine amount female 70 days-84 days 2 0.25 mg/dl 0.05 0.07 automated plasma creatinine analysis 0 61038 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi plasma anion gap controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data ion homeostasis trait female 70 days-84 days 2 21.5 mmol/l 1.5 2.12 standard blood chemistry panel 0 61110 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum chloride level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood chloride amount female 70 days-84 days 2 99.0 mmol/l 0.0 0.0 standard blood chemistry panel 0 62330 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi blood monocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data monocyte quantity female 70 days-84 days 2 0.18 x 1000 cells/ul 0.08 0.11 automated blood cell counting method 0 61716 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70 days-84 days 2 140.0 mmol/l 1.0 1.41 flame atomic emission spectrometry 0 61818 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi total white blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data leukocyte quantity female 70 days-84 days 2 4.95 x 1000 cells/ul 0.05 0.07 automated blood cell counting method 0 61408 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum urea nitrogen level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood urea nitrogen amount male 70 days-84 days 7 21.71 mg/dl 0.52 1.38 standard blood chemistry panel 0 60184 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum calcium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood calcium amount male 70 days-84 days 7 10.4 mg/dl 0.22 0.58 standard blood chemistry panel 0 60256 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum alkaline phosphatase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alkaline phosphatase amount male 70 days-84 days 7 163.57 U/l 6.75 17.86 standard blood chemistry panel 0 60430 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum alkaline phosphatase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alkaline phosphatase amount female 70 days-84 days 2 110.5 U/l 2.5 3.54 standard blood chemistry panel 0 60434 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi mean corpuscular hemoglobin controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70 days-84 days 7 17.11 pg 0.07 0.2 automated blood cell counting method 0 60502 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi mean corpuscular hemoglobin controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70 days-84 days 2 17.9 pg 0.1 0.14 automated blood cell counting method 0 60506 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum albumin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood albumin amount female 70 days-84 days 2 3.95 g/dl 0.05 0.07 standard blood chemistry panel 0 61940 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 2 2.93 E-7mole 0.91 1.28 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63032 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi heart right ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart right ventricle mass male 70 days-84 days 7 0.15 g 0.0 0.01 digital scale post excision weight measurement 0 63307 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi blood lymphocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data lymphocyte quantity male 70 days-84 days 7 4.1 x 1000 cells/ul 0.41 1.09 automated blood cell counting method 0 62090 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi heart left ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart left ventricle mass male 70 days-84 days 7 0.56 g 0.01 0.02 digital scale post excision weight measurement 0 63769 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 2 0.65 g/mg 0.02 0.03 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63169 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum glucose level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood glucose amount female 70 days-84 days 2 154.5 mg/dl 2.5 3.54 standard blood chemistry panel 0 62494 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi hematocrit controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity male 70 days-84 days 7 47.69 % 0.65 1.73 automated blood cell counting method 0 60666 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi blood neutrophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data neutrophil quantity male 70 days-84 days 7 1.3 x 1000 cells/ul 0.15 0.39 automated blood cell counting method 0 60870 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum globulin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood globulin amount male 70 days-84 days 7 2.06 g/dl 0.06 0.17 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 60952 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi plasma creatinine level controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) PhysGen Biochemistry data blood creatinine amount male 70 days-84 days 7 0.3 mg/dl 0.02 0.06 automated plasma creatinine analysis 0 61034 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum total cholesterol level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood cholesterol amount male 70 days-84 days 7 67.0 mg/dl 2.28 6.03 standard blood chemistry panel 0 62398 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70 days-84 days 2 3.4 mmol/l 0.2 0.28 flame atomic emission spectrometry 0 61336 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi mean corpuscular hemoglobin concentration controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70 days-84 days 2 32.15 g/dl 0.15 0.21 automated blood cell counting method 0 61182 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi blood eosinophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data eosinophil quantity male 70 days-84 days 7 0.03 x 1000 cells/ul 0.02 0.05 automated blood cell counting method 0 62244 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi blood eosinophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data eosinophil quantity female 70 days-84 days 2 0.0 x 1000 cells/ul 0.0 0.0 automated blood cell counting method 0 62248 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi blood lymphocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data lymphocyte quantity female 70 days-84 days 2 3.86 x 1000 cells/ul 0.11 0.16 automated blood cell counting method 0 62094 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum urea nitrogen level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood urea nitrogen amount female 70 days-84 days 2 8.5 mg/dl 7.5 10.61 standard blood chemistry panel 0 60188 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum calcium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood calcium amount female 70 days-84 days 2 10.3 mg/dl 0.2 0.28 standard blood chemistry panel 0 60260 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum phosphate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood phosphate amount female 70 days-84 days 2 4.2 mg/dl 3.9 5.52 standard blood chemistry panel 0 61572 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum total cholesterol level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood cholesterol amount female 70 days-84 days 2 51.0 mg/dl 31.0 43.84 standard blood chemistry panel 0 62402 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data kidney mass female 70 days-84 days 3 0.6 g 0.03 0.05 digital scale post excision weight measurement 0 63383 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 3 -8.03 null 0.16 0.27 wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter 63096 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data kidney mass male 70 days-84 days 7 1.0 g 0.02 0.07 digital scale post excision weight measurement 0 63379 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart mass female 70 days-84 days 3 0.55 g 0.03 0.05 digital scale post excision weight measurement 0 63455 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi body length, nose to rump controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length female 70 days-84 days 3 20.0 cm 0.0 0.0 in vivo ruler method 0 63547 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen Vascular data body mass male 70 days-84 days 6 275.83 g 4.46 10.93 whole body digital scale 0 62939 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi mean corpuscular volume controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte size trait female 70 days-84 days 2 55.8 fl 0.0 0.0 automated blood cell counting method 0 60782 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum globulin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood globulin amount female 70 days-84 days 2 2.0 g/dl 0.0 0.0 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 60956 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum total protein level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood total protein amount male 70 days-84 days 7 5.94 g/dl 0.07 0.19 standard blood chemistry panel 0 61260 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum total protein level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood total protein amount female 70 days-84 days 2 5.95 g/dl 0.05 0.07 standard blood chemistry panel 0 61264 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70 days-84 days 7 4.4 mmol/l 0.24 0.64 flame atomic emission spectrometry 0 61332 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi total white blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data leukocyte quantity male 70 days-84 days 7 5.71 x 1000 cells/ul 0.47 1.25 automated blood cell counting method 0 61404 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum total bilirubin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bilirubin amount male 70 days-84 days 7 0.1 mg/dl 0.0 0.0 standard blood chemistry panel 0 62162 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum total bilirubin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bilirubin amount female 70 days-84 days 2 0.1 mg/dl 0.0 0.0 standard blood chemistry panel 0 62166 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi blood hemoglobin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70 days-84 days 2 14.55 g/dl 0.35 0.5 automated blood cell counting method 0 60342 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum aspartate aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood aspartate transaminase amount female 70 days-84 days 2 134.5 U/l 37.5 53.03 standard blood chemistry panel 0 62012 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi body length, nose to tail controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length male 70 days-84 days 7 40.64 cm 0.3 0.8 in vivo ruler method 0 63697 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 3 0.01 umol/l 0.0 0.01 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62773 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum bicarbonate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bicarbonate amount female 70 days-84 days 2 23.0 mmol/l 0.0 0.0 standard blood chemistry panel 0 61644 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data body mass female 70 days-84 days 3 165.33 g 6.69 11.59 whole body digital scale 0 63629 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 2 0.0 umol/l 0.0 0.0 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62777 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 2 26.5 % 13.5 19.09 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62632 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 2 0.77 E-7mole 0.21 0.3 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63028 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi plasma anion gap controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data ion homeostasis trait male 70 days-84 days 7 25.14 mmol/l 0.91 2.41 standard blood chemistry panel 0 61106 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum alanine aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alanine transaminase amount male 70 days-84 days 7 123.86 U/l 49.93 132.11 standard blood chemistry panel 0 61476 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum aspartate aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood aspartate transaminase amount male 70 days-84 days 7 319.0 U/l 62.87 166.33 standard blood chemistry panel 0 62008 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi body length, nose to rump controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length male 70 days-84 days 7 23.79 cm 0.15 0.39 in vivo ruler method 0 63543 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi body length, nose to tail controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length female 70 days-84 days 3 35.0 cm 0.58 1.0 in vivo ruler method 0 63701 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart mass male 70 days-84 days 7 0.84 g 0.01 0.02 digital scale post excision weight measurement 0 63451 529
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 2 -8.43 null 0.27 0.38 wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter 63100 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 3 0.58 g/mg 0.23 0.4 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63165 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 2 -6.56 null 0.14 0.2 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62855 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen Vascular data body mass female 70 days-84 days 3 165.33 g 6.69 11.59 whole body digital scale 0 62943 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum glucose level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood glucose amount male 70 days-84 days 7 228.71 mg/dl 22.25 58.85 standard blood chemistry panel 0 62490 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 2 95.5 % 4.5 6.36 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62628 528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi hematocrit controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity female 70 days-84 days 2 45.15 % 1.35 1.91 automated blood cell counting method 0 60670 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi mean corpuscular volume controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte size trait male 70 days-84 days 7 52.87 fl 0.21 0.55 automated blood cell counting method 0 60778 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi mean corpuscular hemoglobin concentration controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70 days-84 days 7 32.34 g/dl 0.17 0.45 automated blood cell counting method 0 61178 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum chloride level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood chloride amount male 70 days-84 days 7 97.14 mmol/l 0.8 2.12 standard blood chemistry panel 0 62326 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi blood monocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data monocyte quantity male 70 days-84 days 7 0.28 x 1000 cells/ul 0.08 0.21 automated blood cell counting method 0 61712 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70 days-84 days 7 138.86 mmol/l 0.7 1.86 flame atomic emission spectrometry 0 61814 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum alanine aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alanine transaminase amount female 70 days-84 days 2 39.5 U/l 4.5 6.36 standard blood chemistry panel 0 61480 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum phosphate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood phosphate amount male 70 days-84 days 7 8.16 mg/dl 0.32 0.85 standard blood chemistry panel 0 61568 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum bicarbonate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bicarbonate amount male 70 days-84 days 7 21.0 mmol/l 0.53 1.41 standard blood chemistry panel 0 61640 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum albumin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood albumin amount male 70 days-84 days 7 3.89 g/dl 0.05 0.12 standard blood chemistry panel 0 61936 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi blood hemoglobin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70 days-84 days 7 15.43 g/dl 0.14 0.38 automated blood cell counting method 0 60338 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi red blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity male 70 days-84 days 7 9.02 x 10E6 cells/ul 0.11 0.29 automated blood cell counting method 0 60584 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi red blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity female 70 days-84 days 2 8.1 x 10E6 cells/ul 0.24 0.34 automated blood cell counting method 0 60588 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi blood neutrophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data neutrophil quantity female 70 days-84 days 2 0.92 x 1000 cells/ul 0.23 0.33 automated blood cell counting method 0 60874 527