FHH-Nr4a1m1Mcwi |
body length, nose to rump |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
body length |
male |
70 days-84 days |
14 |
23.39 |
cm |
0.3 |
1.11 |
in vivo ruler method |
|
0 |
|
63530 |
529 |
FHH-Nr4a1m1Mcwi |
body weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Vascular data |
body mass |
male |
70 days-84 days |
6 |
250.67 |
g |
8.61 |
21.09 |
whole body digital scale |
|
0 |
|
62927 |
528 |
FHH-Nr4a1m1Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
4 |
68.75 |
% |
3.86 |
7.72 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
62624 |
528 |
FHH-Nr4a1m1Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
4 |
-6.9 |
null |
0.18 |
0.36 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
62839 |
528 |
FHH-Nr4a1m1Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
4 |
1.54 |
E-7mole |
0.42 |
0.83 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
63016 |
528 |
FHH-Nr4a1m1Mcwi |
serum globulin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood globulin amount |
female |
70 days-84 days |
11 |
1.58 |
g/dl |
0.06 |
0.21 |
standard blood chemistry panel |
|
0 |
replaced obsolete serum globulin level term, 1/19/2016 |
60947 |
527 |
FHH-Nr4a1m1Mcwi |
plasma anion gap |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
ion homeostasis trait |
female |
70 days-84 days |
10 |
24.3 |
mmol/l |
1.16 |
3.68 |
standard blood chemistry panel |
|
0 |
|
61101 |
527 |
FHH-Nr4a1m1Mcwi |
serum chloride level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood chloride amount |
male |
70 days-84 days |
11 |
105.0 |
mmol/l |
0.62 |
2.05 |
standard blood chemistry panel |
|
0 |
|
62313 |
527 |
FHH-Nr4a1m1Mcwi |
blood eosinophil count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
eosinophil quantity |
female |
70 days-84 days |
11 |
0.07 |
x 1000 cells/ul |
0.03 |
0.09 |
automated blood cell counting method |
|
0 |
|
62239 |
527 |
FHH-Nr4a1m1Mcwi |
serum calcium level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood calcium amount |
female |
70 days-84 days |
11 |
9.95 |
mg/dl |
0.14 |
0.46 |
standard blood chemistry panel |
|
0 |
|
60251 |
527 |
FHH-Nr4a1m1Mcwi |
mean corpuscular hemoglobin |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood hemoglobin amount |
male |
70 days-84 days |
11 |
17.89 |
pg |
0.1 |
0.34 |
automated blood cell counting method |
|
0 |
|
60489 |
527 |
FHH-Nr4a1m1Mcwi |
heart weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
heart mass |
male |
112 days
| 6 |
3.9 |
g/kg |
0.8 |
0.34 |
post excision weight measurement |
0.0 |
0 |
|
99466 |
2318 |
FHH-Nr4a1m1Mcwi |
creatinine clearance to total kidney weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
glomerular filtration trait |
male |
112 days
| 6 |
0.7 |
ml/min/g |
0.06 |
0.15 |
serum creatinine analysis |
0.0 |
0 |
|
99492 |
2318 |
FHH-Nr4a1m1Mcwi |
creatinine clearance to total kidney weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
glomerular filtration trait |
male |
168 days
| 6 |
0.6 |
ml/min/g |
0.2 |
0.49 |
serum creatinine analysis |
0.0 |
0 |
|
99494 |
2318 |
FHH-Nr4a1m1Mcwi |
serum total cholesterol level |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
blood cholesterol amount |
male |
56 days
| 6 |
71.0 |
mg/dl |
2.1 |
5.14 |
serum total cholesterol measurement test |
0.0 |
0 |
|
99502 |
2318 |
FHH-Nr4a1m1Mcwi |
serum albumin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood albumin amount |
male |
70 days-84 days |
11 |
3.68 |
g/dl |
0.1 |
0.34 |
standard blood chemistry panel |
|
0 |
|
61923 |
527 |
FHH-Nr4a1m1Mcwi |
mean corpuscular hemoglobin concentration |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood hemoglobin amount |
male |
70 days-84 days |
11 |
33.06 |
g/dl |
0.52 |
1.72 |
automated blood cell counting method |
|
0 |
|
61165 |
527 |
FHH-Nr4a1m1Mcwi |
maximum contractile force per wet weight of aorta |
controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70 days-84 days |
6 |
1.41 |
g/mg |
0.13 |
0.32 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
63153 |
528 |
FHH-Nr4a1m1Mcwi |
blood monocyte count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
monocyte quantity |
female |
70 days-84 days |
11 |
0.12 |
x 1000 cells/ul |
0.03 |
0.11 |
automated blood cell counting method |
|
0 |
|
61707 |
527 |
FHH-Nr4a1m1Mcwi |
both kidneys wet weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
kidney mass |
male |
168 days
| 6 |
11.0 |
g/kg |
0.53 |
1.3 |
post excision weight measurement |
0.0 |
0 |
|
99462 |
2318 |
FHH-Nr4a1m1Mcwi |
serum total cholesterol level |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
blood cholesterol amount |
male |
168 days
| 6 |
283.0 |
mg/dl |
29.4 |
72.01 |
serum total cholesterol measurement test |
0.0 |
0 |
|
99506 |
2318 |
FHH-Nr4a1m1Mcwi |
body length, nose to tail |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
body length |
female |
70 days-84 days |
13 |
38.46 |
cm |
0.27 |
0.97 |
in vivo ruler method |
|
0 |
|
63692 |
529 |
FHH-Nr4a1m1Mcwi |
heart right ventricle wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
heart right ventricle mass |
female |
70 days-84 days |
13 |
0.15 |
g |
0.0 |
0.01 |
digital scale post excision weight measurement |
|
0 |
|
63302 |
529 |
FHH-Nr4a1m1Mcwi |
body weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
body mass |
female |
70 days-84 days |
13 |
179.69 |
g |
2.93 |
10.56 |
whole body digital scale |
|
0 |
|
63620 |
529 |
FHH-Nr4a1m1Mcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70 days-84 days |
5 |
-8.22 |
null |
0.05 |
0.1 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
EC50 value is moles/liter |
63092 |
528 |
FHH-Nr4a1m1Mcwi |
serum glucose level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood glucose amount |
male |
70 days-84 days |
11 |
126.55 |
mg/dl |
5.88 |
19.51 |
standard blood chemistry panel |
|
0 |
|
62477 |
527 |
FHH-Nr4a1m1Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
4 |
55.75 |
% |
12.56 |
25.12 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
62616 |
528 |
FHH-Nr4a1m1Mcwi |
body weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Vascular data |
body mass |
female |
70 days-84 days |
6 |
182.67 |
g |
3.18 |
7.79 |
whole body digital scale |
|
0 |
|
62935 |
528 |
FHH-Nr4a1m1Mcwi |
hematocrit |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
erythrocyte quantity |
male |
70 days-84 days |
11 |
43.05 |
% |
0.59 |
1.96 |
automated blood cell counting method |
|
0 |
|
60653 |
527 |
FHH-Nr4a1m1Mcwi |
hematocrit |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
erythrocyte quantity |
female |
70 days-84 days |
11 |
40.14 |
% |
0.85 |
2.81 |
automated blood cell counting method |
|
0 |
|
60661 |
527 |
FHH-Nr4a1m1Mcwi |
serum total bilirubin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood bilirubin amount |
female |
70 days-84 days |
11 |
0.15 |
mg/dl |
0.02 |
0.05 |
standard blood chemistry panel |
|
0 |
|
62157 |
527 |
FHH-Nr4a1m1Mcwi |
serum urea nitrogen level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood urea nitrogen amount |
female |
70 days-84 days |
11 |
18.0 |
mg/dl |
0.84 |
2.79 |
standard blood chemistry panel |
|
0 |
|
60179 |
527 |
FHH-Nr4a1m1Mcwi |
serum bicarbonate level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood bicarbonate amount |
male |
70 days-84 days |
11 |
16.36 |
mmol/l |
0.65 |
2.16 |
standard blood chemistry panel |
|
0 |
|
61627 |
527 |
FHH-Nr4a1m1Mcwi |
serum alkaline phosphatase activity level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood alkaline phosphatase amount |
female |
70 days-84 days |
11 |
129.36 |
U/l |
12.25 |
40.64 |
standard blood chemistry panel |
|
0 |
|
60425 |
527 |
FHH-Nr4a1m1Mcwi |
mean corpuscular hemoglobin |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood hemoglobin amount |
female |
70 days-84 days |
11 |
17.76 |
pg |
0.12 |
0.41 |
automated blood cell counting method |
|
0 |
|
60497 |
527 |
FHH-Nr4a1m1Mcwi |
body weight |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
body mass |
male |
56 days
| 6 |
190.0 |
g |
2.6 |
6.37 |
body weighing method |
0.0 |
0 |
|
99452 |
2318 |
FHH-Nr4a1m1Mcwi |
liver weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
liver mass |
male |
168 days
| 6 |
42.7 |
g/kg |
1.56 |
3.82 |
post excision weight measurement |
0.0 |
0 |
|
99470 |
2318 |
FHH-Nr4a1m1Mcwi |
water drink intake rate |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
drinking behavior trait |
male |
56 days
| 6 |
38.0 |
ml/d |
3.4 |
8.33 |
graduated cylinder |
0.0 |
0 |
|
99472 |
2318 |
FHH-Nr4a1m1Mcwi |
water drink intake rate |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
drinking behavior trait |
male |
112 days
| 6 |
28.0 |
ml/d |
4.4 |
10.78 |
graduated cylinder |
0.0 |
0 |
|
99474 |
2318 |
FHH-Nr4a1m1Mcwi |
timed urine volume |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
urine output |
male |
56 days
| 6 |
37.0 |
ml/d |
2.1 |
5.14 |
urine volume measurement method |
0.0 |
0 |
|
99478 |
2318 |
FHH-Nr4a1m1Mcwi |
urine albumin excretion rate to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
urine albumin amount |
male |
168 days
| 6 |
52.0 |
mg/d/100 g |
5.8 |
14.21 |
urine albumin analysis |
0.0 |
0 |
|
99488 |
2318 |
FHH-Nr4a1m1Mcwi |
serum total cholesterol level |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
blood cholesterol amount |
male |
112 days
| 6 |
122.0 |
mg/dl |
8.7 |
21.31 |
serum total cholesterol measurement test |
0.0 |
0 |
|
99504 |
2318 |
FHH-Nr4a1m1Mcwi |
blood neutrophil count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
neutrophil quantity |
female |
70 days-84 days |
11 |
1.15 |
x 1000 cells/ul |
0.24 |
0.78 |
automated blood cell counting method |
|
0 |
|
60865 |
527 |
FHH-Nr4a1m1Mcwi |
serum albumin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood albumin amount |
female |
70 days-84 days |
11 |
3.78 |
g/dl |
0.07 |
0.23 |
standard blood chemistry panel |
|
0 |
|
61931 |
527 |
FHH-Nr4a1m1Mcwi |
maximum contractile force per wet weight of aorta |
controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70 days-84 days |
5 |
1.63 |
g/mg |
0.08 |
0.17 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
63161 |
528 |
FHH-Nr4a1m1Mcwi |
urine albumin excretion rate to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
urine albumin amount |
male |
56 days
| 6 |
8.0 |
mg/d/100 g |
2.35 |
5.76 |
urine albumin analysis |
0.0 |
0 |
|
99484 |
2318 |
FHH-Nr4a1m1Mcwi |
blood urea nitrogen level |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
blood urea nitrogen amount |
male |
112 days
| 6 |
17.0 |
mg/dl |
0.6 |
1.47 |
serum urea analysis |
0.0 |
0 |
|
99498 |
2318 |
FHH-Nr4a1m1Mcwi |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
kidney mass |
female |
70 days-84 days |
13 |
0.94 |
g |
0.03 |
0.09 |
digital scale post excision weight measurement |
|
0 |
|
63374 |
529 |
FHH-Nr4a1m1Mcwi |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
heart mass |
male |
70 days-84 days |
14 |
1.03 |
g |
0.03 |
0.11 |
digital scale post excision weight measurement |
|
0 |
|
63438 |
529 |
FHH-Nr4a1m1Mcwi |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
heart mass |
female |
70 days-84 days |
13 |
0.83 |
g |
0.01 |
0.04 |
digital scale post excision weight measurement |
|
0 |
|
63446 |
529 |
FHH-Nr4a1m1Mcwi |
serum glucose level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood glucose amount |
female |
70 days-84 days |
11 |
139.09 |
mg/dl |
6.42 |
21.3 |
standard blood chemistry panel |
|
0 |
|
62485 |
527 |
FHH-Nr4a1m1Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) |
PhysGen Biochemistry data |
blood creatinine amount |
male |
70 days-84 days |
11 |
0.24 |
mg/dl |
0.02 |
0.05 |
automated plasma creatinine analysis |
|
0 |
|
61021 |
527 |
FHH-Nr4a1m1Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) |
PhysGen Biochemistry data |
blood creatinine amount |
female |
70 days-84 days |
11 |
0.23 |
mg/dl |
0.04 |
0.13 |
automated plasma creatinine analysis |
|
0 |
|
61029 |
527 |
FHH-Nr4a1m1Mcwi |
plasma anion gap |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
ion homeostasis trait |
male |
70 days-84 days |
11 |
26.27 |
mmol/l |
1.06 |
3.52 |
standard blood chemistry panel |
|
0 |
|
61093 |
527 |
FHH-Nr4a1m1Mcwi |
serum potassium level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood potassium amount |
male |
70 days-84 days |
11 |
4.84 |
mmol/l |
0.2 |
0.68 |
flame atomic emission spectrometry |
|
0 |
|
61319 |
527 |
FHH-Nr4a1m1Mcwi |
total white blood cell count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
leukocyte quantity |
male |
70 days-84 days |
11 |
7.61 |
x 1000 cells/ul |
0.77 |
2.57 |
automated blood cell counting method |
|
0 |
|
61391 |
527 |
FHH-Nr4a1m1Mcwi |
total white blood cell count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
leukocyte quantity |
female |
70 days-84 days |
11 |
6.79 |
x 1000 cells/ul |
0.57 |
1.9 |
automated blood cell counting method |
|
0 |
|
61399 |
527 |
FHH-Nr4a1m1Mcwi |
serum chloride level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood chloride amount |
female |
70 days-84 days |
11 |
103.27 |
mmol/l |
0.47 |
1.56 |
standard blood chemistry panel |
|
0 |
|
62321 |
527 |
FHH-Nr4a1m1Mcwi |
serum sodium level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood sodium amount |
female |
70 days-84 days |
11 |
140.09 |
mmol/l |
0.61 |
2.02 |
flame atomic emission spectrometry |
|
0 |
|
61809 |
527 |
FHH-Nr4a1m1Mcwi |
serum alanine aminotransferase activity level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood alanine transaminase amount |
male |
70 days-84 days |
11 |
44.27 |
U/l |
3.05 |
10.12 |
standard blood chemistry panel |
|
0 |
|
61463 |
527 |
FHH-Nr4a1m1Mcwi |
serum alkaline phosphatase activity level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood alkaline phosphatase amount |
male |
70 days-84 days |
11 |
215.36 |
U/l |
7.79 |
25.84 |
standard blood chemistry panel |
|
0 |
|
60417 |
527 |
FHH-Nr4a1m1Mcwi |
serum aspartate aminotransferase activity level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood aspartate transaminase amount |
male |
70 days-84 days |
11 |
147.45 |
U/l |
10.4 |
34.49 |
standard blood chemistry panel |
|
0 |
|
61995 |
527 |
FHH-Nr4a1m1Mcwi |
red blood cell count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
erythrocyte quantity |
female |
70 days-84 days |
11 |
7.61 |
x 10E6 cells/ul |
0.14 |
0.47 |
automated blood cell counting method |
|
0 |
|
60579 |
527 |
FHH-Nr4a1m1Mcwi |
body weight |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
body mass |
male |
168 days
| 6 |
352.0 |
g |
14.0 |
34.29 |
body weighing method |
0.0 |
0 |
|
99456 |
2318 |
FHH-Nr4a1m1Mcwi |
blood urea nitrogen level |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
blood urea nitrogen amount |
male |
168 days
| 6 |
23.0 |
mg/dl |
1.6 |
3.92 |
serum urea analysis |
0.0 |
0 |
|
99500 |
2318 |
FHH-Nr4a1m1Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
4 |
-7.04 |
null |
0.18 |
0.35 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
62847 |
528 |
FHH-Nr4a1m1Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
4 |
1.19 |
E-7mole |
0.57 |
1.13 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
63024 |
528 |
FHH-Nr4a1m1Mcwi |
timed urine volume |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
urine output |
male |
168 days
| 6 |
24.0 |
ml/d |
2.1 |
5.14 |
urine volume measurement method |
0.0 |
0 |
|
99482 |
2318 |
FHH-Nr4a1m1Mcwi |
serum triglyceride level |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
blood triglyceride amount |
male |
56 days
| 6 |
192.0 |
mg/dl |
43.3 |
106.06 |
serum triglyceride analysis |
0.0 |
0 |
|
99512 |
2318 |
FHH-Nr4a1m1Mcwi |
body length, nose to tail |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
body length |
male |
70 days-84 days |
14 |
41.0 |
cm |
0.54 |
2.04 |
in vivo ruler method |
|
0 |
|
63684 |
529 |
FHH-Nr4a1m1Mcwi |
heart right ventricle wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
heart right ventricle mass |
male |
70 days-84 days |
14 |
0.18 |
g |
0.01 |
0.03 |
digital scale post excision weight measurement |
|
0 |
|
63294 |
529 |
FHH-Nr4a1m1Mcwi |
body weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
body mass |
male |
70 days-84 days |
14 |
233.36 |
g |
5.94 |
22.24 |
whole body digital scale |
|
0 |
|
63612 |
529 |
FHH-Nr4a1m1Mcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70 days-84 days |
5 |
0.01 |
umol/l |
0.0 |
0.0 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
62769 |
528 |
FHH-Nr4a1m1Mcwi |
serum total protein level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood total protein amount |
male |
70 days-84 days |
11 |
5.45 |
g/dl |
0.07 |
0.25 |
standard blood chemistry panel |
|
0 |
|
61247 |
527 |
FHH-Nr4a1m1Mcwi |
serum globulin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood globulin amount |
male |
70 days-84 days |
11 |
1.77 |
g/dl |
0.05 |
0.17 |
standard blood chemistry panel |
|
0 |
replaced obsolete serum globulin level term, 1/19/2016 |
60939 |
527 |
FHH-Nr4a1m1Mcwi |
serum potassium level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood potassium amount |
female |
70 days-84 days |
10 |
4.7 |
mmol/l |
0.36 |
1.14 |
flame atomic emission spectrometry |
|
0 |
|
61327 |
527 |
FHH-Nr4a1m1Mcwi |
serum total cholesterol level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood cholesterol amount |
male |
70 days-84 days |
11 |
80.55 |
mg/dl |
5.16 |
17.11 |
standard blood chemistry panel |
|
0 |
|
62385 |
527 |
FHH-Nr4a1m1Mcwi |
serum total cholesterol level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood cholesterol amount |
female |
70 days-84 days |
11 |
65.36 |
mg/dl |
4.47 |
14.83 |
standard blood chemistry panel |
|
0 |
|
62393 |
527 |
FHH-Nr4a1m1Mcwi |
serum total bilirubin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood bilirubin amount |
male |
70 days-84 days |
11 |
0.13 |
mg/dl |
0.01 |
0.05 |
standard blood chemistry panel |
|
0 |
|
62149 |
527 |
FHH-Nr4a1m1Mcwi |
serum urea nitrogen level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood urea nitrogen amount |
male |
70 days-84 days |
11 |
18.27 |
mg/dl |
0.7 |
2.33 |
standard blood chemistry panel |
|
0 |
|
60171 |
527 |
FHH-Nr4a1m1Mcwi |
serum alanine aminotransferase activity level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood alanine transaminase amount |
female |
70 days-84 days |
11 |
41.0 |
U/l |
2.4 |
7.98 |
standard blood chemistry panel |
|
0 |
|
61471 |
527 |
FHH-Nr4a1m1Mcwi |
serum phosphate level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood phosphate amount |
male |
70 days-84 days |
11 |
8.08 |
mg/dl |
0.28 |
0.93 |
standard blood chemistry panel |
|
0 |
|
61555 |
527 |
FHH-Nr4a1m1Mcwi |
red blood cell count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
erythrocyte quantity |
male |
70 days-84 days |
11 |
7.95 |
x 10E6 cells/ul |
0.1 |
0.34 |
automated blood cell counting method |
|
0 |
|
60571 |
527 |
FHH-Nr4a1m1Mcwi |
serum aspartate aminotransferase activity level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood aspartate transaminase amount |
female |
70 days-84 days |
11 |
157.45 |
U/l |
9.95 |
33.02 |
standard blood chemistry panel |
|
0 |
|
62003 |
527 |
FHH-Nr4a1m1Mcwi |
both kidneys wet weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
kidney mass |
male |
112 days
| 6 |
10.3 |
g/kg |
0.14 |
0.34 |
post excision weight measurement |
0.0 |
0 |
|
99460 |
2318 |
FHH-Nr4a1m1Mcwi |
urine albumin excretion rate to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
urine albumin amount |
male |
112 days
| 6 |
32.0 |
mg/d/100 g |
5.5 |
13.47 |
urine albumin analysis |
0.0 |
0 |
|
99486 |
2318 |
FHH-Nr4a1m1Mcwi |
blood urea nitrogen level |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
blood urea nitrogen amount |
male |
56 days
| 6 |
14.0 |
mg/dl |
0.6 |
1.47 |
serum urea analysis |
0.0 |
0 |
|
99496 |
2318 |
FHH-Nr4a1m1Mcwi |
serum triglyceride level |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
blood triglyceride amount |
male |
56 days
| 6 |
82.0 |
mg/dl |
12.6 |
30.86 |
serum triglyceride analysis |
0.0 |
0 |
|
99510 |
2318 |
FHH-Nr4a1m1Mcwi |
mean corpuscular hemoglobin concentration |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood hemoglobin amount |
female |
70 days-84 days |
11 |
33.47 |
g/dl |
0.22 |
0.72 |
automated blood cell counting method |
|
0 |
|
61173 |
527 |
FHH-Nr4a1m1Mcwi |
blood monocyte count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
monocyte quantity |
male |
70 days-84 days |
11 |
0.15 |
x 1000 cells/ul |
0.05 |
0.17 |
automated blood cell counting method |
|
0 |
|
61699 |
527 |
FHH-Nr4a1m1Mcwi |
heart weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
heart mass |
male |
168 days
| 6 |
3.4 |
g/kg |
0.13 |
0.32 |
post excision weight measurement |
0.0 |
0 |
|
99468 |
2318 |
FHH-Nr4a1m1Mcwi |
water drink intake rate |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
drinking behavior trait |
male |
168 days
| 6 |
22.0 |
ml/d |
2.4 |
5.88 |
graduated cylinder |
0.0 |
0 |
|
99476 |
2318 |
FHH-Nr4a1m1Mcwi |
heart left ventricle wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
heart left ventricle mass |
male |
70 days-84 days |
14 |
0.67 |
g |
0.02 |
0.07 |
digital scale post excision weight measurement |
|
0 |
|
63756 |
529 |
FHH-Nr4a1m1Mcwi |
heart left ventricle wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
heart left ventricle mass |
female |
70 days-84 days |
13 |
0.55 |
g |
0.01 |
0.03 |
digital scale post excision weight measurement |
|
0 |
|
63764 |
529 |
FHH-Nr4a1m1Mcwi |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
kidney mass |
male |
70 days-84 days |
14 |
1.18 |
g |
0.02 |
0.09 |
digital scale post excision weight measurement |
|
0 |
|
63366 |
529 |
FHH-Nr4a1m1Mcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70 days-84 days |
6 |
-8.29 |
null |
0.13 |
0.33 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
EC50 value is moles/liter |
63084 |
528 |
FHH-Nr4a1m1Mcwi |
body length, nose to rump |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
body length |
female |
70 days-84 days |
13 |
21.65 |
cm |
0.2 |
0.72 |
in vivo ruler method |
|
0 |
|
63538 |
529 |
FHH-Nr4a1m1Mcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70 days-84 days |
6 |
0.01 |
umol/l |
0.0 |
0.0 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
62761 |
528 |
FHH-Nr4a1m1Mcwi |
serum total protein level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood total protein amount |
female |
70 days-84 days |
11 |
5.36 |
g/dl |
0.09 |
0.31 |
standard blood chemistry panel |
|
0 |
|
61255 |
527 |
FHH-Nr4a1m1Mcwi |
mean corpuscular volume |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
erythrocyte size trait |
male |
70 days-84 days |
11 |
54.23 |
fl |
1.01 |
3.34 |
automated blood cell counting method |
|
0 |
|
60765 |
527 |
FHH-Nr4a1m1Mcwi |
mean corpuscular volume |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
erythrocyte size trait |
female |
70 days-84 days |
11 |
52.81 |
fl |
0.43 |
1.43 |
automated blood cell counting method |
|
0 |
|
60773 |
527 |
FHH-Nr4a1m1Mcwi |
blood eosinophil count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
eosinophil quantity |
male |
70 days-84 days |
11 |
0.07 |
x 1000 cells/ul |
0.03 |
0.08 |
automated blood cell counting method |
|
0 |
|
62231 |
527 |
FHH-Nr4a1m1Mcwi |
blood lymphocyte count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
lymphocyte quantity |
male |
70 days-84 days |
11 |
5.65 |
x 1000 cells/ul |
0.63 |
2.09 |
automated blood cell counting method |
|
0 |
|
62077 |
527 |
FHH-Nr4a1m1Mcwi |
serum sodium level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood sodium amount |
male |
70 days-84 days |
11 |
142.82 |
mmol/l |
0.46 |
1.54 |
flame atomic emission spectrometry |
|
0 |
|
61801 |
527 |
FHH-Nr4a1m1Mcwi |
serum bicarbonate level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood bicarbonate amount |
female |
70 days-84 days |
11 |
15.91 |
mmol/l |
1.66 |
5.5 |
standard blood chemistry panel |
|
0 |
|
61635 |
527 |
FHH-Nr4a1m1Mcwi |
serum calcium level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood calcium amount |
male |
70 days-84 days |
11 |
10.15 |
mg/dl |
0.15 |
0.5 |
standard blood chemistry panel |
|
0 |
|
60243 |
527 |
FHH-Nr4a1m1Mcwi |
serum phosphate level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood phosphate amount |
female |
70 days-84 days |
11 |
8.12 |
mg/dl |
0.69 |
2.29 |
standard blood chemistry panel |
|
0 |
|
61563 |
527 |
FHH-Nr4a1m1Mcwi |
both kidneys wet weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
kidney mass |
male |
56 days
| 6 |
10.3 |
g/kg |
0.14 |
0.34 |
post excision weight measurement |
0.0 |
0 |
|
99458 |
2318 |
FHH-Nr4a1m1Mcwi |
heart weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
heart mass |
male |
56 days
| 6 |
3.9 |
g/kg |
0.8 |
0.2 |
post excision weight measurement |
0.0 |
0 |
|
99464 |
2318 |
FHH-Nr4a1m1Mcwi |
timed urine volume |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
urine output |
male |
112 days
| 6 |
31.0 |
ml/d |
3.7 |
9.06 |
urine volume measurement method |
0.0 |
0 |
|
99480 |
2318 |
FHH-Nr4a1m1Mcwi |
serum triglyceride level |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
blood triglyceride amount |
male |
56 days
| 6 |
30.0 |
mg/dl |
3.0 |
7.35 |
serum triglyceride analysis |
0.0 |
0 |
|
99508 |
2318 |
FHH-Nr4a1m1Mcwi |
blood hemoglobin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood hemoglobin amount |
male |
70 days-84 days |
11 |
14.21 |
g/dl |
0.14 |
0.46 |
automated blood cell counting method |
|
0 |
|
60325 |
527 |
FHH-Nr4a1m1Mcwi |
blood hemoglobin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood hemoglobin amount |
female |
70 days-84 days |
11 |
13.42 |
g/dl |
0.25 |
0.82 |
automated blood cell counting method |
|
0 |
|
60333 |
527 |
FHH-Nr4a1m1Mcwi |
blood lymphocyte count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
lymphocyte quantity |
female |
70 days-84 days |
11 |
5.45 |
x 1000 cells/ul |
0.58 |
1.93 |
automated blood cell counting method |
|
0 |
|
62085 |
527 |
FHH-Nr4a1m1Mcwi |
blood neutrophil count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
neutrophil quantity |
male |
70 days-84 days |
11 |
1.73 |
x 1000 cells/ul |
0.29 |
0.96 |
automated blood cell counting method |
|
0 |
|
60857 |
527 |
FHH-Nr4a1m1Mcwi |
body weight |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
body mass |
male |
112 days
| 6 |
328.0 |
g |
5.2 |
12.74 |
body weighing method |
0.0 |
0 |
|
99454 |
2318 |
FHH-Nr4a1m1Mcwi |
creatinine clearance to total kidney weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
glomerular filtration trait |
male |
56 days
| 6 |
1.0 |
ml/min/g |
0.12 |
0.29 |
serum creatinine analysis |
0.0 |
0 |
|
99490 |
2318 |