WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
urine norepinephrine excretion rate |
cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine norepinephrine amount |
not specified |
0 days
| 7 |
|
4800.0 |
pmol/4h |
328.83 |
870.0 |
high-performance liquid chromatography |
0.0 |
0 |
hplc |
urine norepinephrine excretion rate |
68656 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
urine norepinephrine excretion rate |
guanethidine (50 mg/kg/d) (for 21 days) then room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine norepinephrine amount |
not specified |
0 days
| 0 |
|
4120.0 |
pmol/4h |
|
550.0 |
high-performance liquid chromatography |
0.0 |
0 |
hplc |
absolute change in urine norepinephrine excretion rate |
68669 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in systolic blood pressure |
guanethidine (50 mg/kg/d) (for 21 days) then room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
arterial blood pressure trait |
not specified |
84 days-112 days |
5 |
serial mean |
36.0 |
mmHg |
2.24 |
5.0 |
radiotelemetry |
16200.0 |
0 |
10 s every 5 min |
|
68677 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
heart weight to body weight ratio |
cold ambient air exposure (4 degrees C) (for 90 days) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
heart mass |
not specified |
112 days
| 10 |
|
3.18 |
g/kg |
0.07 |
0.22 |
post excision weight measurement |
0.0 |
0 |
|
|
68697 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
both kidneys wet weight |
cold ambient air exposure (4 degrees C) (for 90 days) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
kidney mass |
not specified |
112 days
| 10 |
|
3.32 |
g |
0.07 |
0.23 |
post excision weight measurement |
0.0 |
0 |
|
|
68700 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in mean arterial blood pressure |
air-jet exposure (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
35.0 |
mmHg |
3.0 |
7.35 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84538 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in heart rate |
air-jet exposure (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
heart pumping trait |
male |
98 days
| 6 |
|
105.0 |
beats/min |
12.0 |
29.39 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84559 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in plasma norepinephrine level |
room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
blood norepinephrine amount |
not specified |
0 days
| 5 |
|
7.14 |
pmol/l |
1.19 |
2.66 |
high-performance liquid chromatography |
0.0 |
0 |
|
difference in plasma norepinephrine between baseline and 4 degrees |
68671 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
heart rate |
control condition |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
heart pumping trait |
male |
98 days
| 6 |
|
326.0 |
beats/min |
12.0 |
29.39 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84560 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
mean arterial blood pressure |
control condition |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
107.0 |
mmHg |
2.0 |
4.9 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
69084 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in diastolic blood pressure |
room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
arterial blood pressure trait |
not specified |
84 days-112 days |
4 |
serial mean |
38.0 |
mmHg |
3.5 |
7.0 |
radiotelemetry |
16200.0 |
0 |
10 s every 5 min |
|
68678 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in heart rate |
guanethidine (50 mg/kg/d) (for 21 days) then room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
heart pumping trait |
not specified |
84 days-112 days |
5 |
serial mean |
179.0 |
beats/min |
6.26 |
14.0 |
radiotelemetry |
16200.0 |
0 |
10 s every 5 min |
|
68687 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in heart rate |
room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
heart pumping trait |
not specified |
84 days-112 days |
6 |
serial mean |
122.0 |
beats/min |
12.66 |
31.0 |
radiotelemetry |
16200.0 |
0 |
10 s every 5 min |
|
68688 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
systolic blood pressure |
control condition |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
arterial blood pressure trait |
not specified |
112 days
| 10 |
|
148.0 |
mmHg |
1.77 |
5.6 |
tail cuff plethysmography |
0.0 |
0 |
10 s every 5 min |
|
68690 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
heart weight to body weight ratio |
control condition |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
heart mass |
not specified |
112 days
| 10 |
|
3.03 |
g/kg |
0.06 |
0.18 |
post excision weight measurement |
0.0 |
0 |
|
|
68695 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio |
air-jet exposure (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
kidney sympathetic nerve activity |
male |
98 days
| 6 |
|
216.0 |
% |
51.0 |
124.92 |
implanted wire electrode recording method |
0.0 |
0 |
|
percent change rsna |
84540 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in mean arterial blood pressure |
vehicle control condition (2 ul) (for 0 hours) then air-jet exposure (for 0 hours) then angiotensin II (20 ng) then phenylephrine (3 ug) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
50.0 |
mmHg |
3.0 |
7.35 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84572 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
heart rate |
control condition |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
heart pumping trait |
male |
98 days
| 6 |
|
329.0 |
beats/min |
13.0 |
31.84 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84561 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in heart rate |
air-jet exposure (for 0 hours) then vehicle control condition (2 ul) (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
heart pumping trait |
male |
98 days
| 6 |
|
-5.0 |
beats/min |
7.0 |
17.15 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84564 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
urine vanillylmandelic acid excretion rate |
sodium chloride solution (for 21 days) then room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine vanillylmandelic acid amount |
not specified |
0 days
| 0 |
|
3120.0 |
pmol/4h |
|
200.0 |
high-performance liquid chromatography |
0.0 |
0 |
hplc |
absolute change in vanillylmandelic acid excretion rate |
68668 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in mean arterial blood pressure |
air-jet exposure (for 0 hours) then hexamethonium (40 mg/kg) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
-48.0 |
mmHg |
6.0 |
14.7 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
69090 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in heart rate |
air-jet exposure (for 0 hours) then candesartan (1 ug) (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
heart pumping trait |
male |
98 days
| 6 |
|
4.0 |
beats/min |
12.0 |
29.39 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84565 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
cell membrane potential |
control condition |
Iigaya K, et al., Hypertension. 2008 Dec 1. |
action potential trait |
not specified |
0 days-4 days |
8 |
|
-49.3 |
mV |
1.06 |
3.0 |
whole-cell patch clamp technique |
600 |
0 |
|
irregularly firing neurons |
65898 |
634 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
urine norepinephrine excretion rate |
room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine norepinephrine amount |
not specified |
0 days
| 7 |
|
3790.0 |
pmol/4h |
415.76 |
1100.0 |
high-performance liquid chromatography |
0.0 |
0 |
hplc |
absolute change in urine norepinephrine excretion rate |
68659 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
urine vanillylmandelic acid excretion rate |
room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine vanillylmandelic acid amount |
not specified |
0 days
| 7 |
|
1540.0 |
pmol/4h |
188.98 |
500.0 |
high-performance liquid chromatography |
0.0 |
0 |
hplc |
absolute change in vanillylmandelic acid excretion rate |
68665 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
urine vanillylmandelic acid excretion rate |
guanethidine (50 mg/kg/d) (for 21 days) then room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine vanillylmandelic acid amount |
not specified |
0 days
| 0 |
|
2020.0 |
pmol/4h |
|
400.0 |
high-performance liquid chromatography |
0.0 |
0 |
hplc |
absolute change in vanillylmandelic acid excretion rate |
68667 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
urine norepinephrine excretion rate |
sodium chloride solution (for 21 days) then room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine norepinephrine amount |
not specified |
0 days
| 0 |
|
4890.0 |
pmol/4h |
|
640.0 |
high-performance liquid chromatography |
0.0 |
0 |
|
absolute change in urine norepinephrine excretion rate |
68670 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in diastolic blood pressure |
guanethidine (50 mg/kg/d) (for 21 days) then room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
arterial blood pressure trait |
not specified |
84 days-112 days |
5 |
serial mean |
32.0 |
mmHg |
1.79 |
4.0 |
radiotelemetry |
16200.0 |
0 |
10 s every 5 min |
|
68680 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in systolic blood pressure |
room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
arterial blood pressure trait |
not specified |
84 days-112 days |
6 |
serial mean |
25.0 |
mmHg |
1.63 |
4.0 |
radiotelemetry |
16200.0 |
0 |
10 s every 5 min |
|
68681 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in heart rate |
room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
heart pumping trait |
not specified |
84 days-112 days |
4 |
serial mean |
213.0 |
beats/min |
12.5 |
25.0 |
radiotelemetry |
16200.0 |
0 |
10 s every 5 min |
|
68685 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
heart wet weight |
control condition |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
heart mass |
not specified |
112 days
| 10 |
|
1.19 |
g |
0.03 |
0.09 |
post excision weight measurement |
0.0 |
0 |
|
|
68694 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
both kidneys wet weight |
control condition |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
kidney mass |
not specified |
112 days
| 10 |
|
3.02 |
g |
0.06 |
0.18 |
post excision weight measurement |
0.0 |
0 |
|
|
68698 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
both kidneys wet weight to body weight ratio |
cold ambient air exposure (4 degrees C) (for 90 days) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
kidney mass |
not specified |
112 days
| 10 |
|
8.17 |
g/kg |
0.11 |
0.34 |
post excision weight measurement |
0.0 |
0 |
|
|
68701 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
both adrenal glands weight to body weight ratio |
control condition |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
adrenal gland mass |
not specified |
112 days
| 10 |
|
16.0 |
mg/100g |
0.63 |
2.0 |
post excision weight measurement |
0.0 |
0 |
|
|
68703 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
both adrenal glands wet weight |
cold ambient air exposure (4 degrees C) (for 90 days) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
adrenal gland mass |
not specified |
112 days
| 10 |
|
65.0 |
mg |
2.21 |
7.0 |
post excision weight measurement |
0.0 |
0 |
|
|
68704 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
percent change in mean arterial blood pressure |
air-jet exposure (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
33.0 |
% |
3.0 |
7.35 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84543 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in mean arterial blood pressure |
candesartan (1 ug) (for 0 hours) then air-jet exposure (for 0 hours) then angiotensin II (20 ng) then phenylephrine (3 ug) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
56.0 |
mmHg |
2.0 |
4.9 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84573 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in mean arterial blood pressure |
air-jet exposure (for 0 hours) then candesartan (1 ug) (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
-2.0 |
mmHg |
3.0 |
7.35 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84554 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in mean arterial blood pressure |
air-jet exposure (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
36.0 |
mmHg |
2.0 |
4.9 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84557 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
urine vanillylmandelic acid excretion rate |
cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine vanillylmandelic acid amount |
not specified |
0 days
| 7 |
|
2200.0 |
pmol/4h |
117.17 |
310.0 |
high-performance liquid chromatography |
0.0 |
0 |
hplc |
urine vanillylmandelic acid exretion rate |
68662 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
systolic blood pressure |
cold ambient air exposure (4 degrees C) (for 90 days) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
arterial blood pressure trait |
not specified |
112 days
| 10 |
|
157.0 |
mmHg |
1.39 |
4.4 |
tail cuff plethysmography |
0.0 |
0 |
10 s every 5 min |
|
68691 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
body weight |
cold ambient air exposure (4 degrees C) (for 90 days) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
body mass |
not specified |
112 days
| 10 |
|
406.0 |
g |
5.06 |
16.0 |
body weighing method |
0.0 |
0 |
|
|
68693 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
heart wet weight |
cold ambient air exposure (4 degrees C) (for 90 days) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
heart mass |
not specified |
112 days
| 10 |
|
1.29 |
g |
0.03 |
0.09 |
post excision weight measurement |
0.0 |
0 |
|
|
68696 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in urine norepinephrine level |
cold ambient air exposure (4 degrees C) (for 6 hours) |
Xiao B, et al., J Hypertens. 2010 Nov 8. |
urine norepinephrine amount |
male |
84 days
| 16 |
|
69.67 |
nmol/h |
|
|
high-performance liquid chromatography |
0.0 |
0 |
|
nmol/6h |
84591 |
990 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in mean arterial blood pressure |
candesartan (1 ug) (for 0 hours) then air-jet exposure (for 0 hours) then angiotensin II (20 ng) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
-1.0 |
mmHg |
4.0 |
9.8 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84569 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in mean arterial blood pressure |
air-jet exposure (for 0 hours) then vehicle control condition (2 ul) (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
-1.0 |
mmHg |
2.0 |
4.9 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84555 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
mean arterial blood pressure |
control condition |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
105.0 |
mmHg |
4.0 |
9.8 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84548 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in mean arterial blood pressure |
vehicle control condition (2 ul) (for 0 hours) then air-jet exposure (for 0 hours) then angiotensin II (20 ng) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
32.0 |
mmHg |
2.0 |
4.9 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84568 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
cell membrane potential |
control condition |
Iigaya K, et al., Hypertension. 2008 Dec 1. |
action potential trait |
not specified |
0 days-4 days |
7 |
|
-46.4 |
mV |
0.87 |
2.3 |
whole-cell patch clamp technique |
600 |
0 |
|
regularly firing neurons |
65894 |
634 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
heart rate |
control condition |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
heart pumping trait |
male |
98 days
| 6 |
|
321.0 |
beats/min |
11.0 |
26.94 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
69087 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in systolic blood pressure |
room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
arterial blood pressure trait |
not specified |
84 days-112 days |
4 |
serial mean |
44.0 |
mmHg |
3.5 |
7.0 |
radiotelemetry |
16200.0 |
0 |
10 s every 5 min |
|
68675 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in diastolic blood pressure |
room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
arterial blood pressure trait |
not specified |
84 days-112 days |
6 |
serial mean |
23.0 |
mmHg |
1.63 |
4.0 |
radiotelemetry |
16200.0 |
0 |
10 s every 5 min |
|
68683 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
body weight |
control condition |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
body mass |
not specified |
112 days
| 10 |
|
393.0 |
g |
5.66 |
17.9 |
body weighing method |
0.0 |
0 |
|
|
68692 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
both kidneys wet weight to body weight ratio |
control condition |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
kidney mass |
not specified |
112 days
| 10 |
|
7.69 |
g/kg |
0.11 |
0.35 |
post excision weight measurement |
0.0 |
0 |
|
|
68699 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
both adrenal glands wet weight |
control condition |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
adrenal gland mass |
not specified |
112 days
| 10 |
|
64.0 |
mg |
5.38 |
17.0 |
post excision weight measurement |
0.0 |
0 |
|
|
68702 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
both adrenal glands weight to body weight ratio |
cold ambient air exposure (4 degrees C) (for 90 days) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
adrenal gland mass |
not specified |
112 days
| 10 |
|
16.0 |
mg/100g |
0.63 |
2.0 |
post excision weight measurement |
0.0 |
0 |
|
|
68705 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in mean arterial blood pressure |
air-jet exposure (for 0 hours) then candesartan (1 ug) (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
-10.0 |
mmHg |
1.0 |
2.45 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
85199 |
1120 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
absolute change in plasma epinephrine level |
room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
blood epinephrine amount |
not specified |
0 days
| 5 |
|
1.63 |
pmol/l |
0.54 |
1.21 |
high-performance liquid chromatography |
0.0 |
0 |
hplc |
difference in plasma epinephrine between base and 4 degrees |
68673 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
systolic blood pressure |
control condition |
Xiao B, et al., J Hypertens. 2010 Nov 8. |
arterial blood pressure trait |
male |
84 days
| 16 |
serial mean |
125.0 |
mmHg |
|
|
tail cuff plethysmography |
0.0 |
0 |
|
avg of 5 measurements |
68741 |
990 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
mean arterial blood pressure |
control condition |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
103.0 |
mmHg |
2.0 |
4.9 |
vascular indwelling catheter method |
0.0 |
0 |
|
|
84551 |
1120 |