Phenominer Database Results (138 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
WKY/Izm cell membrane potential control condition Iigaya K, et al., Hypertension. 2008 Dec 1. action potential trait not specified 0 days-4 days 8 -57.0 mV 0.35 1.0 whole-cell patch clamp technique 600 0 irregularly firing neurons 65897 634
WKY/Izm body weight controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) then controlled fat content diet (26 %) (for 14 days) and controlled potassium content diet (0.44 %) (for 14 days) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. body mass male 119 days 10 325.0 g 5.34 16.9 body weighing method 0 12491 263
WKY/Izm serum total cholesterol level fasting (0 null) (for 16 hours) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. blood cholesterol amount male 91 days 5 75.68 mg/dl 3.09 6.91 serum total cholesterol measurement test 0 0 64852 115
WKY/Izm serum triglyceride level fasting (0 null) (for 16 hours) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. blood triglyceride amount male 91 days 5 24.78 mg/dl 2.65 5.94 serum triglyceride analysis 0 0 64858 115
WKY/Izm urine vanillylmandelic acid excretion rate cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. urine vanillylmandelic acid amount not specified 0 days 14 1650.0 pmol/4h 125.61 470.0 high-performance liquid chromatography 0.0 0 hplc urine vanillylmandelic acid exretion rate 68663 971
WKY/Izm body weight specific pathogen-free condition NBRP Body Weight data body mass male 35 days 6 101.2 g 1.55 3.8 whole body digital scale 0 70931 21
WKY/Izm body weight specific pathogen-free condition NBRP Body Weight data body mass male 70 days 6 285.9 g 3.63 8.9 whole body digital scale 0 70932 21
WKY/Izm adipocyte maximal glucose uptake controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) then insulin (50000 pmol/l) (for 1 hours) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. adipocyte glucose uptake trait male 105 days 10 144.5 x 1000 cpm/cell 3.48 11.0 radioactive glucose uptake assay with liquid scintillation counting 0.0 0 67928 263
WKY/Izm absolute change in mean arterial blood pressure air-jet exposure (for 0 hours) then hexamethonium (40 mg/kg) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 -49.0 mmHg 5.0 12.25 vascular indwelling catheter method 0.0 0 69089 1120
WKY/Izm serum free fatty acids level controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) then fasting (for 16 hours) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. blood free fatty acid amount male 98 days 10 0.02 mmol/l 0.0 0.0 serum free fatty acid analysis 0.0 0 67923 263
WKY/Izm absolute change in systolic blood pressure room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. arterial blood pressure trait not specified 84 days-112 days 6 serial mean 19.0 mmHg 0.82 2.0 radiotelemetry 16200.0 0 10 s every 5 min 68682 971
WKY/Izm absolute change in diastolic blood pressure room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. arterial blood pressure trait not specified 84 days-112 days 6 serial mean 17.0 mmHg 0.82 2.0 radiotelemetry 16200.0 0 10 s every 5 min 68684 971
WKY/Izm absolute change in systolic blood pressure physical restraint in mechanical restrainer (for 3 hours) Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 94 days 6 serial mean 3.0 mmHg radiotelemetry 0.0 0 avg of 5 measurements for 84610 990
WKY/Izm mean corpuscular hemoglobin fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood hemoglobin amount male 70 days 6 19.2 pg 0.08 0.2 automated cell/particle size/count analysis method 0 Sysmex, F-800 type 79840 1498
WKY/Izm white blood cell count fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data leukocyte quantity male 70 days 6 6.0 x 1000 cells/ul 0.2 0.5 automated cell/particle size/count analysis method 0 Sysmex, F-800 type 79842 1498
WKY/Izm plasma chloride level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood chloride amount male 70 days 6 106.0 mmol/l 0.41 1.0 automated blood electrolyte analysis 0 Analytical intruments, PVA alpha II 79862 1498
WKY/Izm absolute change in mean arterial blood pressure air-jet exposure (for 0 hours) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 22.0 mmHg 2.0 4.9 vascular indwelling catheter method 0.0 0 84537 1120
WKY/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84 days 16 serial mean 118.0 mmHg tail cuff plethysmography 0.0 0 avg of 5 measurements for 84607 990
WKY/Izm absolute change in mean arterial blood pressure air-jet exposure (for 0 hours) then vehicle control condition (2 ul) (for 0 hours) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 -3.0 mmHg 2.0 4.9 vascular indwelling catheter method 0.0 0 84553 1120
WKY/Izm heart wet weight specific pathogen-free condition NBRP Organ Weight data heart mass male 70 days 6 0.95 g 0.01 0.03 Shimadzu electronic balance post excision weight measurement 0 72875 41
WKY/Izm both kidneys wet weight as percentage of body weight specific pathogen-free condition NBRP Organ Weight data kidney mass male 70 days 6 0.67 % 0.01 0.02 Shimadzu electronic balance post excision weight measurement 0 72882 41
WKY/Izm both adrenal glands wet weight specific pathogen-free condition NBRP Organ Weight data adrenal gland mass male 70 days 6 57.2 mg 1.71 4.2 Shimadzu electronic balance post excision weight measurement 0 72883 41
WKY/Izm systolic blood pressure control condition Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. arterial blood pressure trait female 91 days 5 127.0 mmHg 5.0 11.18 tail cuff plethysmography 0 0 11683 115
WKY/Izm absolute change in adipocyte glucose uptake controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) then insulin (50000 pmol/l) (for 1 hours) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. adipocyte glucose uptake trait male 105 days 10 106.6 cpm x 1000/cell 4.33 13.7 radioactive glucose uptake assay with liquid scintillation counting 0.0 0 67932 263
WKY/Izm mean corpuscular volume fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data erythrocyte size trait male 70 days 6 56.3 fl 0.41 1.0 automated cell/particle size/count analysis method 0 Sysmex, F-800 type 79839 1498
WKY/Izm mean corpuscular hemoglobin concentration fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood hemoglobin amount male 70 days 6 34.1 g/dl 0.29 0.7 automated cell/particle size/count analysis method 0 Sysmex, F-800 type 79841 1498
WKY/Izm blood basophil count to total leukocyte count ratio fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data basophil quantity male 70 days 6 0.0 % 0.0 0.0 automated differential white blood cell count test 0 May-Giemsa staining 79863 1498
WKY/Izm blood monocyte count to total leukocyte count ratio fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data monocyte quantity male 70 days 6 0.0 % 0.41 1.0 automated differential white blood cell count test 0 May-Giemsa staining 79868 1498
WKY/Izm brain wet weight specific pathogen-free condition NBRP Organ Weight data brain mass male 70 days 6 2.14 g 0.02 0.04 Shimadzu electronic balance post excision weight measurement 0 72873 41
WKY/Izm absolute change in mean arterial blood pressure vehicle control condition (2 ul) (for 0 hours) then air-jet exposure (for 0 hours) then angiotensin II (20 ng) then phenylephrine (3 ug) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 50.0 mmHg 2.0 4.9 vascular indwelling catheter method 0.0 0 84570 1120
WKY/Izm absolute change in heart rate air-jet exposure (for 0 hours) then vehicle control condition (2 ul) (for 0 hours) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. heart pumping trait male 98 days 6 0.0 beats/min 6.0 14.7 vascular indwelling catheter method 0.0 0 84562 1120
WKY/Izm cell membrane potential control condition Iigaya K, et al., Hypertension. 2008 Dec 1. action potential trait not specified 0 days-4 days 7 -55.4 mV 2.12 5.6 whole-cell patch clamp technique 600 0 regularly firing neurons 65893 634
WKY/Izm systolic blood pressure control condition Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. arterial blood pressure trait male 91 days 5 131.8 mmHg 2.0 4.47 tail cuff plethysmography 0 11679 115
WKY/Izm serum triglyceride level controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) then fasting (for 16 hours) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. blood triglyceride amount male 98 days 10 11.0 mg/dl 1.08 3.4 serum triglyceride analysis 0 12499 263
WKY/Izm retroperitoneal fat pad weight to body weight ratio control condition (0 null) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. retroperitoneal fat pad mass male 91 days 5 1.17 % 0.1 0.22 post excision weight measurement 0 0 64844 115
WKY/Izm body weight control condition (0 null) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. body mass male 91 days 5 318.0 g 5.9 13.19 body weighing method 0 0 64830 115
WKY/Izm heart weight to body weight ratio control condition (0 null) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. heart mass female 91 days 5 2.76 g/kg 0.09 0.2 post excision weight measurement 0 0 64840 115
WKY/Izm urine vanillylmandelic acid excretion rate room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. urine vanillylmandelic acid amount not specified 0 days 14 1080.0 pmol/4h 160.36 600.0 high-performance liquid chromatography 0.0 0 hplc absolute change in vanillylmandelic acid excretion rate 68666 971
WKY/Izm adipocyte maximal glucose uptake to basal glucose uptake ratio controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) then insulin (50000 pmol/l) (for 1 hours) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. adipocyte glucose uptake trait male 105 days 10 3.88 null 0.21 0.65 radioactive glucose uptake assay with liquid scintillation counting 0.0 0 67930 263
WKY/Izm absolute change in adipocyte free fatty acid secretion controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) then isoproterenol (200 nmol/l) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. adipocyte free fatty acid secretion trait male 105 days 10 8.39 pmol/cell 0.57 1.79 lipolysis assay measuring free fatty acid release 0.0 0 67934 263
WKY/Izm blood hemoglobin level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood hemoglobin amount male 70 days 6 16.1 g/dl 0.2 0.5 automated cell/particle size/count analysis method 0 Sysmex, F-800 type 79837 1498
WKY/Izm non-specified leukocyte count to total leukocyte count ratio fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data leukocyte quantity male 70 days 6 0.0 % 0.0 0.0 automated differential white blood cell count test 0 May-Giemsa staining unidentified differential wbc 79869 1498
WKY/Izm absolute change in heart rate air-jet exposure (for 0 hours) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. heart pumping trait male 98 days 6 85.0 beats/min 8.0 19.6 vascular indwelling catheter method 0.0 0 84558 1120
WKY/Izm absolute change in mean arterial blood pressure vehicle control condition (2 ul) (for 0 hours) then air-jet exposure (for 0 hours) then angiotensin II (20 ng) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 27.0 mmHg 3.0 7.35 vascular indwelling catheter method 0.0 0 84566 1120
WKY/Izm absolute change in mean arterial blood pressure candesartan (1 ug) (for 0 hours) then air-jet exposure (for 0 hours) then angiotensin II (20 ng) then phenylephrine (3 ug) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 53.0 mmHg 3.0 7.35 vascular indwelling catheter method 0.0 0 84571 1120
WKY/Izm lung wet weight specific pathogen-free condition NBRP Organ Weight data lung mass male 70 days 6 1.09 g 0.02 0.05 Shimadzu electronic balance post excision weight measurement 0 72877 41
WKY/Izm both testes wet weight specific pathogen-free condition NBRP Organ Weight data testis mass male 70 days 6 2.89 g 0.02 0.06 Shimadzu electronic balance post excision weight measurement 0 72887 41
WKY/Izm serum triglyceride level controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) then controlled fat content diet (26 %) (for 14 days) and controlled potassium content diet (0.44 %) (for 14 days) then fasting (for 16 hours) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. blood triglyceride amount male 113 days 10 15.0 mg/dl 1.8 5.7 serum triglyceride analysis 0 12508 263
WKY/Izm mean arterial blood pressure control condition Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 108.0 mmHg 3.0 7.35 vascular indwelling catheter method 0.0 0 69083 1120
WKY/Izm heart rate control condition Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. heart pumping trait male 98 days 6 317.0 beats/min 14.0 34.29 vascular indwelling catheter method 0.0 0 69086 1120
WKY/Izm plasma creatinine level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood creatinine amount male 70 days 6 0.22 mg/dl 0.0 0.01 automated plasma creatinine analysis 0 Hitachi, model 7170 79857 1498
WKY/Izm serum free fatty acids level fasting (0 null) (for 16 hours) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. blood free fatty acid amount female 91 days 5 0.68 mmol/l 0.12 0.27 serum free fatty acid analysis 0 0 64867 115
WKY/Izm mean arterial blood pressure control condition Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 106.0 mmHg 3.0 7.35 vascular indwelling catheter method 0.0 0 84546 1120
WKY/Izm body weight controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. body mass male 91 days-98 days 10 318.0 g 3.76 11.9 body weighing method 0 12430 263
WKY/Izm serum total cholesterol level controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) then controlled fat content diet (26 %) (for 14 days) and controlled potassium content diet (0.44 %) (for 14 days) then fasting (for 16 hours) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. blood cholesterol amount male 119 days 10 60.4 mg/dl 1.04 3.3 serum total cholesterol measurement test 0 12504 263
WKY/Izm retroperitoneal fat pad weight to body weight ratio control condition (0 null) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. retroperitoneal fat pad mass female 91 days 5 1.07 % 0.04 0.08 post excision weight measurement 0 0 64847 115
WKY/Izm serum total cholesterol level fasting (0 null) (for 16 hours) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. blood cholesterol amount female 91 days 5 77.99 mg/dl 1.16 2.59 serum total cholesterol measurement test 0 0 64855 115
WKY/Izm absolute change in systolic blood pressure room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. arterial blood pressure trait not specified 84 days-112 days 5 serial mean 35.0 mmHg 3.58 8.0 radiotelemetry 16200.0 0 10 s every 5 min 68676 971
WKY/Izm absolute change in diastolic blood pressure room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. arterial blood pressure trait not specified 84 days-112 days 5 serial mean 33.0 mmHg 3.13 7.0 radiotelemetry 16200.0 0 10 s every 5 min 68679 971
WKY/Izm absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio physical restraint in mechanical restrainer (for 3 hours) Xiao B, et al., J Hypertens. 2010 Nov 8. heart pumping trait male 91 days 5 serial mean 0.3 null wire electrode telemetric electrocardiography with power spectral analysis 0.0 0 avg of 5 measurements for 84609 990
WKY/Izm activated partial thromboplastin time fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood coagulation trait male 70 days 6 15.1 s 0.2 0.5 automated coagulometer method 0 Sysmex, CA-3000 type 79845 1498
WKY/Izm plasma urea nitrogen level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood urea nitrogen amount male 70 days 6 5.5 mmol/l 0.25 0.61 automated plasma analysis 0 PMID:15591307 79856 1498
WKY/Izm total plasma calcium level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood calcium amount male 70 days 6 9.9 mg/dl 0.04 0.1 automated blood electrolyte analysis 0 Hitachi, model 7170 79859 1498
WKY/Izm heart rate control condition Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. heart pumping trait male 98 days 6 306.0 beats/min 12.0 29.39 vascular indwelling catheter method 0.0 0 84549 1120
WKY/Izm urine chloride level 0.9% sodium chloride solution (25 ml/kg) NBRP Urine Volume and Urine Electrolyte data urine chloride amount male 63 days 6 152.0 mEq/L 9.8 24.0 automated urine analysis 0 95538 1662
WKY/Izm urine chloride excretion rate to body weight ratio 0.9% sodium chloride solution (25 ml/kg) NBRP Urine Volume and Urine Electrolyte data urine chloride amount male 63 days 6 322.0 uEq/100g/6 hrs 28.58 70.0 automated urine analysis 0 95539 1662
WKY/Izm mean arterial blood pressure control condition Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 107.0 mmHg 4.0 9.8 vascular indwelling catheter method 0.0 0 84547 1120
WKY/Izm systolic blood pressure specific pathogen-free condition NBRP Blood Pressure and Heart Rate data arterial blood pressure trait male 56 days-70 days 6 serial mean 113.0 mmHg 4.49 11.0 tail cuff photoplethysmography 0 NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan 75186 14
WKY/Izm heart rate specific pathogen-free condition NBRP Blood Pressure and Heart Rate data heart pumping trait male 56 days-70 days 6 serial mean 433.0 beats/min 9.8 24.0 tail cuff photoplethysmography 0 NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan 75187 14
WKY/Izm serum total cholesterol level control condition Kato N, et al., Arterioscler Thromb Vasc Biol 2000 Jan;20(1):223-9 blood cholesterol amount male 112 days 5 72.54 mg/dl 1.54 3.45 serum total cholesterol measurement test 0.0 0 some flavor of WKY 68957 1033
WKY/Izm prothrombin time fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood coagulation trait male 70 days 6 16.1 s 0.16 0.4 automated coagulometer method 0 Sysmex, CA-3000 type 79844 1498
WKY/Izm plasma glucose level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood glucose amount male 70 days 6 129.0 mg/dl 2.86 7.0 automated plasma analysis 0 PMID:15591307 79852 1498
WKY/Izm blood band neutrophil count to total leukocyte count ratio fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data neutrophil quantity male 70 days 6 0.0 % 0.0 0.0 automated differential white blood cell count test 0 May-Giemsa staining band neutrophil % 79865 1498
WKY/Izm plasma glucose level fasting (0 null) (for 16 hours) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. blood glucose amount male 91 days 5 147.06 mg/dl 5.76 12.88 blood glucose analysis 0 0 64870 115
WKY/Izm lung weight to body weight ratio specific pathogen-free condition NBRP Organ Weight data lung mass male 70 days 6 0.41 % 0.01 0.02 Shimadzu electronic balance post excision weight measurement 0 72878 41
WKY/Izm both adrenal glands weight to body weight ratio specific pathogen-free condition NBRP Organ Weight data adrenal gland mass male 70 days 6 21.4 mg/100g 0.57 1.4 Shimadzu electronic balance post excision weight measurement 0 72884 41
WKY/Izm spleen weight to body weight ratio specific pathogen-free condition NBRP Organ Weight data spleen mass male 70 days 6 0.17 % 0.0 0.01 Shimadzu electronic balance post excision weight measurement 0 72886 41
WKY/Izm systolic blood pressure controlled fat content diet (5 %) (for 63 days) and controlled potassium content diet (0.75 %) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. arterial blood pressure trait male 91 days 10 132.2 mmHg 2.18 6.9 tail cuff plethysmography 0 13277 263
WKY/Izm epididymal fat pad weight to body weight ratio control condition Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. epididymal fat pad mass male 91 days 5 1.34 % 0.03 0.07 post excision weight measurement testis 0 0 65000 115
WKY/Izm body weight control condition (0 null) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. body mass female 91 days 5 200.8 g 3.1 6.93 body weighing method 0 0 64833 115
WKY/Izm urine norepinephrine excretion rate room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. urine norepinephrine amount not specified 0 days 14 1890.0 pmol/4h 227.17 850.0 high-performance liquid chromatography 0.0 0 hplc absolute change in urine norepinephrine excretion rate 68660 971
WKY/Izm serum total cholesterol level control condition Kato N, et al., Arterioscler Thromb Vasc Biol 2000 Jan;20(1):223-9 blood cholesterol amount female 112 days 5 80.6 mg/dl 2.45 5.48 serum total cholesterol measurement test 0.0 0 some flavor of WKY 68958 1033
WKY/Izm absolute change in plasma epinephrine level room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. blood epinephrine amount not specified 0 days 5 0.68 pmol/l 0.62 1.38 high-performance liquid chromatography 0.0 0 hplc difference in plasma epinephrine between base and 4 degrees 68674 971
WKY/Izm adipocyte basal glucose uptake controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. adipocyte glucose uptake trait male 105 days 10 37.9 x 1000 cpm/cell 1.52 4.8 radioactive glucose uptake assay with liquid scintillation counting 0.0 0 67926 263
WKY/Izm absolute change in heart rate room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. heart pumping trait not specified 84 days-112 days 5 serial mean 221.0 beats/min 6.71 15.0 radiotelemetry 16200.0 0 10 s every 5 min 68686 971
WKY/Izm absolute change in heart rate room temperature (for 0.5 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. heart pumping trait not specified 84 days-112 days 6 serial mean 107.0 beats/min 6.12 15.0 radiotelemetry 16200.0 0 10 s every 5 min 68689 971
WKY/Izm absolute change in urine norepinephrine level cold ambient air exposure (4 degrees C) (for 6 hours) Xiao B, et al., J Hypertens. 2010 Nov 8. urine norepinephrine amount male 84 days 16 28.83 nmol/h high-performance liquid chromatography 0.0 0 nmol/6h 84608 990
WKY/Izm hematocrit fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data erythrocyte quantity male 70 days 6 47.2 % 0.73 1.8 automated cell/particle size/count analysis method 0 Sysmex, F-800 type 79838 1498
WKY/Izm platelet count fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data platelet quantity male 70 days 6 863.0 x 1000 /ul 9.8 24.0 automated cell/particle size/count analysis method 0 Sysmex, F-800 type 79843 1498
WKY/Izm plasma albumin level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood albumin amount male 70 days 6 0.38 g/l 0.0 0.01 automated plasma albumin analysis 0 Hitachi, model 7170 79850 1498
WKY/Izm plasma albumin to plasma total protein ratio fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood albumin amount male 70 days 6 1.66 null 0.02 0.04 automated plasma protein analysis 0 Hitachi, model 7170 plasma albumin to plasma total protein ratio 79851 1498
WKY/Izm plasma triglyceride level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood triglyceride amount male 70 days 6 0.35 mmol/l 0.04 0.09 automated plasma analysis 0 PMID:15591307 79854 1498
WKY/Izm blood eosinophil count to total leukocyte count ratio fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data eosinophil quantity male 70 days 6 1.0 % 0.41 1.0 automated differential white blood cell count test 0 May-Giemsa staining 79864 1498
WKY/Izm blood segmented neutrophil count to total leukocyte count ratio fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data neutrophil quantity male 70 days 6 19.0 % 1.63 4.0 automated differential white blood cell count test 0 May-Giemsa staining segmented neutrophil % 79866 1498
WKY/Izm blood lymphocyte count to total leukocyte count ratio fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data lymphocyte quantity male 70 days 6 80.0 % 1.63 4.0 automated differential white blood cell count test 0 May-Giemsa staining 79867 1498
WKY/Izm timed urine volume 0.9% sodium chloride solution (25 ml/kg) NBRP Urine Volume and Urine Electrolyte data urine output male 63 days 6 24.36 ml/d 1.85 4.52 metabolic cage urine volume measurement method 0 95532 1662
WKY/Izm timed urine volume to body weight ratio 0.9% sodium chloride solution (25 ml/kg) NBRP Urine Volume and Urine Electrolyte data urine output male 63 days 6 0.06 ul/min/g 0.0 0.01 metabolic cage urine volume measurement method 0 95533 1662
WKY/Izm urine sodium level 0.9% sodium chloride solution (25 ml/kg) NBRP Urine Volume and Urine Electrolyte data urine sodium amount male 63 days 6 109.5 mmol/l 8.65 21.2 automated urine analysis 0 Analytical intruments, PVA alpha II 95534 1662
WKY/Izm urine potassium level 0.9% sodium chloride solution (25 ml/kg) NBRP Urine Volume and Urine Electrolyte data urine potassium amount male 63 days 6 84.6 mmol/l 3.67 9.0 automated urine analysis 0 Analytical intruments, PVA alpha II 95536 1662
WKY/Izm absolute change in heart rate air-jet exposure (for 0 hours) then candesartan (1 ug) (for 0 hours) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. heart pumping trait male 98 days 6 -5.0 beats/min 11.0 26.94 vascular indwelling catheter method 0.0 0 84563 1120
WKY/Izm systolic blood pressure controlled visible light exposure Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 94 days 0 serial mean 112.0 mmHg 10.0 radiotelemetry 0.0 0 avg of 5 measurements for 84612 990
WKY/Izm spleen wet weight specific pathogen-free condition NBRP Organ Weight data spleen mass male 70 days 6 0.45 g 0.01 0.01 Shimadzu electronic balance post excision weight measurement 0 72885 41
WKY/Izm serum total cholesterol level controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (for 70 days) then fasting Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. blood cholesterol amount male 98 days 10 73.3 mg/dl 2.34 7.4 serum total cholesterol measurement test 0 12495 263
WKY/Izm body weight specific pathogen-free condition NBRP Body Weight data body mass male 42 days 6 151.4 g 2.16 5.3 whole body digital scale 0 70933 21
WKY/Izm plasma alanine aminotransferase activity level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood alanine transaminase amount male 70 days 6 26.0 U/l 0.41 1.0 automated plasma analysis 0 PMID:15591307 79847 1498
WKY/Izm plasma total protein level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood total protein amount male 70 days 6 60.0 mg/ml 0.82 2.0 automated plasma total protein analysis 0 Hitachi, model 7170 79849 1498
WKY/Izm plasma total bilirubin level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood bilirubin amount male 70 days 6 0.05 mg/dl 0.0 0.01 automated plasma analysis 0 PMID:15591307 total plasma bilirubin level 79855 1498
WKY/Izm plasma sodium level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood sodium amount male 70 days 6 145.6 mmol/l 0.33 0.8 automated blood electrolyte analysis 0 Analytical intruments, PVA alpha II 79860 1498
WKY/Izm plasma glucose level fasting (0 null) (for 16 hours) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. blood glucose amount female 91 days 5 207.18 mg/dl 10.44 23.34 blood glucose analysis 0 0 64875 115
WKY/Izm serum free fatty acids level fasting (0 null) (for 16 hours) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. blood free fatty acid amount male 91 days 5 0.39 mmol/l 0.02 0.04 serum free fatty acid analysis 0 0 64864 115
WKY/Izm heart weight to body weight ratio specific pathogen-free condition NBRP Organ Weight data heart mass male 70 days 6 3.54 g/kg 0.04 0.09 Shimadzu electronic balance post excision weight measurement 0 72876 41
WKY/Izm both kidneys wet weight specific pathogen-free condition NBRP Organ Weight data kidney mass male 70 days 6 1.8 g 0.03 0.07 Shimadzu electronic balance post excision weight measurement 0 72881 41
WKY/Izm heart rate control condition Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. heart pumping trait male 98 days 6 320.0 beats/min 11.0 26.94 vascular indwelling catheter method 0.0 0 84550 1120
WKY/Izm serum triglyceride level fasting (0 null) (for 16 hours) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. blood triglyceride amount female 91 days 5 40.71 mg/dl 7.96 17.81 serum triglyceride analysis 0 0 64861 115
WKY/Izm heart weight to body weight ratio control condition (0 null) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. heart mass male 91 days 5 2.47 g/kg 0.09 0.2 post excision weight measurement 0 0 64837 115
WKY/Izm urine norepinephrine excretion rate cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. urine norepinephrine amount not specified 0 days 14 2670.0 pmol/4h 171.05 640.0 high-performance liquid chromatography 0.0 0 hplc urine norepinephrine excretion rate 68657 971
WKY/Izm absolute change in plasma norepinephrine level room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. blood norepinephrine amount not specified 0 days 5 3.92 pmol/l 1.01 2.26 high-performance liquid chromatography 0.0 0 hplc difference in plasma norepinephrine between base and 4 degrees 68672 971
WKY/Izm serum free fatty acids level controlled fat content diet (5 %) (for 70 days) and controlled potassium content diet (0.75 %) (for 70 days) then controlled fat content diet (26 %) (for 14 days) and controlled potassium content diet (0.44 %) (for 14 days) then fasting (for 16 hours) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. blood free fatty acid amount male 113 days 10 0.03 mmol/l 0.0 0.01 serum free fatty acid analysis 0.0 0 67924 263
WKY/Izm absolute change in systolic blood pressure cold ambient air exposure (4 degrees C) (for 3 hours) Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 94 days 6 serial mean 17.0 mmHg radiotelemetry 0.0 0 avg of 5 measurements for 84611 990
WKY/Izm plasma aspartate aminotransferase activity level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood aspartate transaminase amount male 70 days 6 81.0 U/l 1.63 4.0 automated plasma analysis 0 PMID:15591307 79846 1498
WKY/Izm plasma alkaline phosphatase activity level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood alkaline phosphatase amount male 70 days 6 377.0 IU/l 8.98 22.0 automated plasma analysis 0 PMID:15591307 79848 1498
WKY/Izm plasma total cholesterol level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood cholesterol amount male 70 days 6 95.0 mg/dl 2.45 6.0 automated plasma analysis 0 PMID:15591307 79853 1498
WKY/Izm plasma phosphate level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood phosphate amount male 70 days 6 7.4 mg/dl 0.08 0.2 automated blood electrolyte analysis 0 Hitachi, model 7170 79858 1498
WKY/Izm plasma potassium level fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data blood potassium amount male 70 days 6 4.33 mmol/l 0.1 0.25 automated blood electrolyte analysis 0 Analytical intruments, PVA alpha II 79861 1498
WKY/Izm stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio air-jet exposure (for 0 hours) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. kidney sympathetic nerve activity male 98 days 6 78.0 % 20.0 48.99 implanted wire electrode recording method 0.0 0 percent change rsna 84539 1120
WKY/Izm urine sodium excretion rate to body weight ratio 0.9% sodium chloride solution (25 ml/kg) NBRP Urine Volume and Urine Electrolyte data urine sodium amount male 63 days 6 0.01 uEq/min/g 0.0 0.0 automated urine analysis 0 Analytical intruments, PVA alpha II 95535 1662
WKY/Izm urine potassium excretion rate to body weight ratio 0.9% sodium chloride solution (25 ml/kg) NBRP Urine Volume and Urine Electrolyte data urine potassium amount male 63 days 6 179.0 uEq/100g/6 hrs 11.43 28.0 automated urine analysis 0 Analytical intruments, PVA alpha II 95537 1662
WKY/Izm absolute change in mean arterial blood pressure candesartan (1 ug) (for 0 hours) then air-jet exposure (for 0 hours) then angiotensin II (20 ng) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 0.0 mmHg 1.0 2.45 vascular indwelling catheter method 0.0 0 84567 1120
WKY/Izm absolute change in mean arterial blood pressure air-jet exposure (for 0 hours) then candesartan (1 ug) (for 0 hours) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 -3.0 mmHg 1.0 2.45 vascular indwelling catheter method 0.0 0 84545 1120
WKY/Izm absolute change in mean arterial blood pressure air-jet exposure (for 0 hours) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 23.0 mmHg 2.0 4.9 vascular indwelling catheter method 0.0 0 84556 1120
WKY/Izm systolic blood pressure controlled exposure to darkness Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 94 days 0 serial mean 120.0 mmHg 17.0 radiotelemetry 0.0 0 avg of 5 measurements for 84614 990
WKY/Izm body temperature specific pathogen-free condition NBRP Body Temperature data body temperature trait male 56 days-70 days 6 serial mean 38.0 degrees C 0.2 0.5 digital rectal thermometry 0 75188 22
WKY/Izm brain weight to body weight ratio specific pathogen-free condition NBRP Organ Weight data brain mass male 70 days 6 0.8 % 0.01 0.03 Shimadzu electronic balance post excision weight measurement 0 72874 41
WKY/Izm liver wet weight specific pathogen-free condition NBRP Organ Weight data liver mass male 70 days 6 7.16 g 0.17 0.42 Shimadzu electronic balance post excision weight measurement 0 72879 41
WKY/Izm liver weight as percentage of body weight specific pathogen-free condition NBRP Organ Weight data liver mass male 70 days 6 2.67 % 0.04 0.09 Shimadzu electronic balance post excision weight measurement 0 72880 41
WKY/Izm both testes wet weight to body weight ratio specific pathogen-free condition NBRP Organ Weight data testis mass male 70 days 6 1.08 % 0.01 0.03 Shimadzu electronic balance post excision weight measurement 0 72888 41
WKY/Izm red blood cell count fasting (for 16 hours) NBRP Hematology & Blood Biochemistry data erythrocyte quantity male 70 days 6 8.37 x 10E6 cells/ul 0.11 0.28 automated cell/particle size/count analysis method 0 Sysmex, F-800 type 79836 1498
WKY/Izm absolute change in mean arterial blood pressure air-jet exposure (for 0 hours) then candesartan (1 ug) (for 0 hours) Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. arterial blood pressure trait male 98 days 6 0.0 mmHg 2.0 4.9 vascular indwelling catheter method 0.0 0 84552 1120