SHRSP/Izm |
partial pressure of blood oxygen |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
blood oxygen amount |
male |
70 days-84 days |
8 |
|
111.0 |
mmHg |
3.18 |
9.0 |
automated blood gas analysis |
|
0 |
|
0 |
|
|
|
65511 |
567 |
SHRSP/Izm |
partial pressure of blood carbon dioxide (Pco2) |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
blood carbon dioxide amount |
male |
150 days
| 5 |
|
42.2 |
mmHg |
0.98 |
2.2 |
automated blood gas analysis |
|
0 |
|
0 |
|
|
|
65515 |
567 |
SHRSP/Izm |
partial pressure of blood carbon dioxide (Pco2) |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
blood carbon dioxide amount |
male |
150 days
| 7 |
|
39.7 |
mmHg |
0.91 |
2.4 |
automated blood gas analysis |
|
0 |
|
0 |
|
|
|
65516 |
567 |
SHRSP/Izm |
head temperature |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
head temperature trait |
male |
150 days
| 7 |
|
36.3 |
degrees C |
0.08 |
0.2 |
in vivo thermometry |
|
0 |
|
0 |
|
|
|
65957 |
567 |
SHRSP/Izm |
percentage of study population developing cerebrovascular lesions during a period of time |
controlled sodium content drinking water (1 %) (for 28 days) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
cerebrovascular system integrity trait |
female |
112 days
| 10 |
|
60.0 |
% |
|
|
ex vivo light microscopy |
MA:0000168 |
0 |
|
0 |
|
|
|
65295 |
115 |
SHRSP/Izm |
retroperitoneal fat pad weight to body weight ratio |
control condition (0 null) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
retroperitoneal fat pad mass |
male |
91 days
| 5 |
|
0.76 |
% |
0.06 |
0.12 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
64841 |
115 |
SHRSP/Izm |
mean corpuscular volume |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte size trait |
male |
70 days
| 6 |
|
57.4 |
fl |
1.14 |
2.8 |
automated cell/particle size/count analysis method |
|
|
|
0 |
|
Sysmex, F-800 type |
|
79803 |
1498 |
SHRSP/Izm |
plasma aspartate aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood aspartate transaminase amount |
male |
70 days
| 6 |
|
86.0 |
U/l |
1.63 |
4.0 |
automated plasma analysis |
|
|
|
0 |
|
PMID:15591307 |
|
79810 |
1498 |
SHRSP/Izm |
plasma alanine aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alanine transaminase amount |
male |
70 days
| 6 |
|
45.0 |
U/l |
0.82 |
2.0 |
automated plasma analysis |
|
|
|
0 |
|
PMID:15591307 |
|
79811 |
1498 |
SHRSP/Izm |
plasma total protein level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood total protein amount |
male |
70 days
| 6 |
|
67.0 |
mg/ml |
1.22 |
3.0 |
automated plasma total protein analysis |
|
|
|
0 |
|
Hitachi, model 7170 |
|
79813 |
1498 |
SHRSP/Izm |
plasma phosphate level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood phosphate amount |
male |
70 days
| 6 |
|
5.5 |
mg/dl |
0.45 |
1.1 |
automated blood electrolyte analysis |
|
|
|
0 |
|
Hitachi, model 7170 |
|
79824 |
1498 |
SHRSP/Izm |
timed urine volume |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63 days
| 6 |
|
14.4 |
ml/d |
0.73 |
1.8 |
metabolic cage urine volume measurement method |
|
|
|
0 |
|
|
|
95524 |
1662 |
SHRSP/Izm |
timed urine volume to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63 days
| 6 |
|
0.04 |
ul/min/g |
0.0 |
0.01 |
metabolic cage urine volume measurement method |
|
|
|
0 |
|
|
|
95525 |
1662 |
SHRSP/Izm |
urine potassium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63 days
| 6 |
|
124.0 |
uEq/100g/6 hrs |
8.57 |
21.0 |
automated urine analysis |
|
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
95529 |
1662 |
SHRSP/Izm |
heart rate |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
heart pumping trait |
male |
56 days-70 days |
6 |
serial mean |
445.0 |
beats/min |
24.9 |
61.0 |
tail cuff photoplethysmography |
|
|
|
0 |
|
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
75184 |
14 |
SHRSP/Izm |
body temperature |
specific pathogen-free condition |
NBRP Body Temperature data |
body temperature trait |
male |
56 days-70 days |
6 |
serial mean |
38.1 |
degrees C |
0.12 |
0.3 |
digital rectal thermometry |
|
|
|
0 |
|
|
|
75185 |
22 |
SHRSP/Izm |
heart wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70 days
| 6 |
|
1.0 |
g |
0.02 |
0.05 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72859 |
41 |
SHRSP/Izm |
heart weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70 days
| 6 |
|
4.45 |
g/kg |
0.09 |
0.22 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72860 |
41 |
SHRSP/Izm |
body weight |
control condition (0 null) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
body mass |
male |
91 days
| 5 |
|
245.4 |
g |
5.9 |
13.19 |
body weighing method |
|
0 |
|
0 |
|
|
|
64828 |
115 |
SHRSP/Izm |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
35 days
| 6 |
|
105.4 |
g |
1.84 |
4.5 |
whole body digital scale |
|
|
|
0 |
|
|
|
70929 |
21 |
SHRSP/Izm |
activated partial thromboplastin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70 days
| 6 |
|
14.5 |
s |
0.78 |
1.9 |
automated coagulometer method |
|
|
|
0 |
|
Sysmex, CA-3000 type |
|
79809 |
1498 |
SHRSP/Izm |
plasma albumin to plasma total protein ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70 days
| 6 |
|
1.53 |
null |
0.02 |
0.06 |
automated plasma protein analysis |
|
|
|
0 |
|
Hitachi, model 7170 |
plasma albumin to plasma total protein ratio |
79815 |
1498 |
SHRSP/Izm |
serum total cholesterol level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood cholesterol amount |
female |
91 days
| 5 |
|
67.57 |
mg/dl |
2.32 |
5.18 |
serum total cholesterol measurement test |
|
0 |
|
0 |
|
|
|
64853 |
115 |
SHRSP/Izm |
serum free fatty acids level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood free fatty acid amount |
male |
91 days
| 5 |
|
0.61 |
mmol/l |
0.08 |
0.18 |
serum free fatty acid analysis |
|
0 |
|
0 |
|
|
|
64862 |
115 |
SHRSP/Izm |
cell membrane potential |
control condition |
Iigaya K, et al., Hypertension. 2008 Dec 1. |
action potential trait |
not specified |
0 days-4 days |
7 |
|
-45.4 |
mV |
1.36 |
3.6 |
whole-cell patch clamp technique |
|
600 |
|
0 |
|
|
regularly firing neurons |
65896 |
634 |
SHRSP/Izm |
core body temperature |
control condition (for 150 days) |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
body temperature trait |
male |
150 days
| 7 |
|
37.4 |
degrees C |
0.19 |
0.5 |
in vivo thermometry |
|
0 |
|
0 |
|
|
|
65958 |
567 |
SHRSP/Izm |
hematocrit |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
erythrocyte quantity |
male |
150 days
| 7 |
|
44.0 |
% |
1.13 |
3.0 |
hematocrit analysis |
|
0 |
|
0 |
|
|
|
65524 |
567 |
SHRSP/Izm |
blood pH |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
blood acidity-alkalinity balance trait |
male |
150 days
| 5 |
|
7.46 |
null |
0.01 |
0.02 |
blood pH analysis |
|
0 |
|
0 |
|
|
|
65527 |
567 |
SHRSP/Izm |
percentage of study population developing cerebrovascular lesions during a period of time |
controlled sodium content drinking water (1 %) (for 14 days) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
cerebrovascular system integrity trait |
male |
98 days
| 12 |
|
50.0 |
% |
|
|
ex vivo light microscopy |
MA:0000168 |
0 |
|
0 |
|
|
|
65291 |
115 |
SHRSP/Izm |
serum total cholesterol level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood cholesterol amount |
male |
91 days
| 5 |
|
54.83 |
mg/dl |
1.93 |
4.32 |
serum total cholesterol measurement test |
|
0 |
|
0 |
|
|
|
64850 |
115 |
SHRSP/Izm |
serum free fatty acids level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood free fatty acid amount |
female |
91 days
| 5 |
|
0.6 |
mmol/l |
0.05 |
0.11 |
serum free fatty acid analysis |
|
0 |
|
0 |
|
|
|
64865 |
115 |
SHRSP/Izm |
brain infarction volume |
control condition (for 153 days) |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
brain integrity trait |
male |
153 days
| 17 |
|
103.4 |
mm3 |
6.01 |
24.8 |
ex vivo light microscopy |
|
0 |
MCA occlusion |
3 |
days |
|
|
65951 |
567 |
SHRSP/Izm |
heart weight to body weight ratio |
control condition (0 null) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
heart mass |
male |
91 days
| 5 |
|
4.07 |
g/kg |
0.12 |
0.27 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
64835 |
115 |
SHRSP/Izm |
heart weight to body weight ratio |
control condition (0 null) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
heart mass |
female |
91 days
| 5 |
|
4.84 |
g/kg |
0.24 |
0.54 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
64838 |
115 |
SHRSP/Izm |
urine norepinephrine excretion rate |
cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine norepinephrine amount |
not specified |
0 days
| 6 |
|
6330.0 |
pmol/4h |
326.6 |
800.0 |
high-performance liquid chromatography |
|
0.0 |
|
0 |
|
hplc |
urine norepinephrine excretion rate |
68655 |
971 |
SHRSP/Izm |
absolute change in mean arterial blood pressure |
air-jet exposure (for 0 hours) then hexamethonium (40 mg/kg) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
-102.0 |
mmHg |
5.0 |
12.25 |
vascular indwelling catheter method |
|
0.0 |
|
0 |
|
|
|
69091 |
1120 |
SHRSP/Izm |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
42 days
| 6 |
|
140.7 |
g |
2.16 |
5.3 |
whole body digital scale |
|
|
|
0 |
|
|
|
70930 |
21 |
SHRSP/Izm |
plasma high density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood HDL cholesterol amount |
male |
70 days
| 6 |
|
38.6 |
mg/dl |
1.71 |
4.2 |
automated plasma analysis |
|
|
|
0 |
|
PMID:15591307 |
|
79818 |
1498 |
SHRSP/Izm |
plasma low density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood LDL cholesterol amount |
male |
70 days
| 6 |
|
6.0 |
mg/dl |
0.41 |
1.0 |
automated plasma analysis |
|
|
|
0 |
|
PMID:15591307 |
|
79819 |
1498 |
SHRSP/Izm |
plasma sodium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood sodium amount |
male |
70 days
| 6 |
|
146.5 |
mmol/l |
0.24 |
0.6 |
automated blood electrolyte analysis |
|
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
79826 |
1498 |
SHRSP/Izm |
plasma potassium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood potassium amount |
male |
70 days
| 6 |
|
4.6 |
mmol/l |
0.78 |
1.91 |
automated blood electrolyte analysis |
|
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
79827 |
1498 |
SHRSP/Izm |
non-specified leukocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
|
0 |
|
May-Giemsa staining |
unidentified differential wbc |
79835 |
1498 |
SHRSP/Izm |
stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio |
air-jet exposure (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
kidney sympathetic nerve activity |
male |
98 days
| 6 |
|
261.0 |
% |
36.0 |
88.18 |
implanted wire electrode recording method |
|
0.0 |
|
0 |
|
|
percent change rsna |
84541 |
1120 |
SHRSP/Izm |
absolute change in mean arterial blood pressure |
air-jet exposure (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
47.0 |
mmHg |
1.0 |
2.45 |
vascular indwelling catheter method |
|
0.0 |
|
0 |
|
|
|
84542 |
1120 |
SHRSP/Izm |
percent change in mean arterial blood pressure |
air-jet exposure (for 0 hours) |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
28.0 |
% |
2.0 |
4.9 |
vascular indwelling catheter method |
|
0.0 |
|
0 |
|
|
|
84544 |
1120 |
SHRSP/Izm |
systolic blood pressure |
control condition |
Xiao B, et al., J Hypertens. 2010 Nov 8. |
arterial blood pressure trait |
male |
84 days
| 18 |
serial mean |
213.0 |
mmHg |
|
|
tail cuff plethysmography |
|
0.0 |
|
0 |
|
|
avg of 5 measurements for |
84602 |
990 |
SHRSP/Izm |
absolute change in systolic blood pressure |
physical restraint in mechanical restrainer (for 3 hours) |
Xiao B, et al., J Hypertens. 2010 Nov 8. |
arterial blood pressure trait |
male |
94 days
| 4 |
serial mean |
23.0 |
mmHg |
|
|
radiotelemetry |
|
0.0 |
|
0 |
|
|
avg of 5 measurements for |
84605 |
990 |
SHRSP/Izm |
absolute change in systolic blood pressure |
cold ambient air exposure (4 degrees C) (for 3 hours) |
Xiao B, et al., J Hypertens. 2010 Nov 8. |
arterial blood pressure trait |
male |
94 days
| 4 |
serial mean |
35.0 |
mmHg |
|
|
radiotelemetry |
|
0.0 |
|
0 |
|
|
avg of 5 measurements for |
84606 |
990 |
SHRSP/Izm |
urine sodium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63 days
| 6 |
|
126.1 |
mmol/l |
9.92 |
24.3 |
automated urine analysis |
|
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
95526 |
1662 |
SHRSP/Izm |
urine potassium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63 days
| 6 |
|
80.7 |
mmol/l |
4.98 |
12.2 |
automated urine analysis |
|
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
95528 |
1662 |
SHRSP/Izm |
urine chloride excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63 days
| 6 |
|
234.0 |
uEq/100g/6 hrs |
8.57 |
21.0 |
automated urine analysis |
|
|
|
0 |
|
|
|
95531 |
1662 |
SHRSP/Izm |
systolic blood pressure |
control condition |
Xiao B, et al., J Hypertens. 2010 Nov 8. |
arterial blood pressure trait |
male |
84 days
| 18 |
serial mean |
213.0 |
mmHg |
3.77 |
16.0 |
tail cuff plethysmography |
|
0.0 |
|
0 |
|
|
avg of 5 measurements for |
84620 |
990 |
SHRSP/Izm |
brain wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70 days
| 6 |
|
1.85 |
g |
0.02 |
0.04 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72857 |
41 |
SHRSP/Izm |
spleen wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70 days
| 6 |
|
0.41 |
g |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72869 |
41 |
SHRSP/Izm |
systolic blood pressure |
control condition |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
arterial blood pressure trait |
female |
91 days
| 5 |
|
200.2 |
mmHg |
8.7 |
19.45 |
tail cuff plethysmography |
|
|
|
0 |
|
|
|
11681 |
115 |
SHRSP/Izm |
platelet count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
platelet quantity |
male |
70 days
| 6 |
|
647.0 |
x 1000 /ul |
39.19 |
96.0 |
automated cell/particle size/count analysis method |
|
|
|
0 |
|
Sysmex, F-800 type |
|
79807 |
1498 |
SHRSP/Izm |
plasma alkaline phosphatase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alkaline phosphatase amount |
male |
70 days
| 6 |
|
393.0 |
IU/l |
7.35 |
18.0 |
automated plasma analysis |
|
|
|
0 |
|
PMID:15591307 |
|
79812 |
1498 |
SHRSP/Izm |
plasma triglyceride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood triglyceride amount |
male |
70 days
| 6 |
|
0.29 |
mmol/l |
0.03 |
0.08 |
automated plasma analysis |
|
|
|
0 |
|
PMID:15591307 |
|
79820 |
1498 |
SHRSP/Izm |
plasma creatinine level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood creatinine amount |
male |
70 days
| 6 |
|
0.28 |
mg/dl |
0.01 |
0.03 |
automated plasma creatinine analysis |
|
|
|
0 |
|
Hitachi, model 7170 |
|
79823 |
1498 |
SHRSP/Izm |
total plasma calcium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood calcium amount |
male |
70 days
| 6 |
|
10.1 |
mg/dl |
0.12 |
0.3 |
automated blood electrolyte analysis |
|
|
|
0 |
|
Hitachi, model 7170 |
|
79825 |
1498 |
SHRSP/Izm |
head temperature |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
head temperature trait |
male |
70 days-84 days |
8 |
|
36.4 |
degrees C |
0.11 |
0.3 |
in vivo thermometry |
|
0 |
|
0 |
|
|
|
65953 |
567 |
SHRSP/Izm |
both kidneys wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70 days
| 6 |
|
1.7 |
g |
0.04 |
0.1 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72865 |
41 |
SHRSP/Izm |
spleen weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70 days
| 6 |
|
0.18 |
% |
0.0 |
0.01 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72870 |
41 |
SHRSP/Izm |
cell membrane potential |
control condition |
Iigaya K, et al., Hypertension. 2008 Dec 1. |
action potential trait |
not specified |
0 days-4 days |
8 |
|
-50.0 |
mV |
0.0 |
0.0 |
whole-cell patch clamp technique |
|
600 |
|
0 |
|
|
irregularly firing neurons |
65900 |
634 |
SHRSP/Izm |
partial pressure of blood oxygen |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
blood oxygen amount |
male |
150 days
| 7 |
|
98.0 |
mmHg |
4.54 |
12.0 |
automated blood gas analysis |
|
0 |
|
0 |
|
|
|
65513 |
567 |
SHRSP/Izm |
hematocrit |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
erythrocyte quantity |
male |
70 days-84 days |
8 |
|
42.0 |
% |
0.71 |
2.0 |
hematocrit analysis |
|
0 |
|
0 |
|
|
|
65523 |
567 |
SHRSP/Izm |
head temperature |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
head temperature trait |
male |
150 days
| 7 |
|
36.3 |
degrees C |
0.19 |
0.5 |
in vivo thermometry |
|
0 |
|
0 |
|
|
|
65961 |
567 |
SHRSP/Izm |
epididymal fat pad weight to body weight ratio |
control condition (for 63 days) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
epididymal fat pad mass |
male |
91 days
| 5 |
|
1.11 |
% |
0.06 |
0.14 |
post excision weight measurement |
testis |
0 |
|
0 |
|
|
|
64996 |
115 |
SHRSP/Izm |
percentage of study population developing cerebrovascular lesions during a period of time |
controlled sodium content drinking water (1 %) (for 28 days) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
cerebrovascular system integrity trait |
male |
112 days
| 12 |
|
100.0 |
% |
|
|
ex vivo light microscopy |
MA:0000168 |
0 |
|
0 |
|
|
|
65294 |
115 |
SHRSP/Izm |
retroperitoneal fat pad weight to body weight ratio |
control condition (0 null) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
retroperitoneal fat pad mass |
female |
91 days
| 5 |
|
0.67 |
% |
0.03 |
0.08 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
64845 |
115 |
SHRSP/Izm |
red blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70 days
| 6 |
|
9.5 |
x 10E6 cells/ul |
0.12 |
0.29 |
automated cell/particle size/count analysis method |
|
|
|
0 |
|
Sysmex, F-800 type |
|
79800 |
1498 |
SHRSP/Izm |
plasma glucose level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood glucose amount |
male |
70 days
| 6 |
|
165.0 |
mg/dl |
5.72 |
14.0 |
automated plasma analysis |
|
|
|
0 |
|
PMID:15591307 |
|
79816 |
1498 |
SHRSP/Izm |
plasma urea nitrogen level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood urea nitrogen amount |
male |
70 days
| 6 |
|
7.64 |
mmol/l |
0.47 |
1.14 |
automated plasma analysis |
|
|
|
0 |
|
PMID:15591307 |
|
79822 |
1498 |
SHRSP/Izm |
lung weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70 days
| 6 |
|
0.41 |
% |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72862 |
41 |
SHRSP/Izm |
liver wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70 days
| 6 |
|
6.52 |
g |
0.19 |
0.46 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72863 |
41 |
SHRSP/Izm |
both testes wet weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70 days
| 6 |
|
1.21 |
% |
0.02 |
0.06 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72872 |
41 |
SHRSP/Izm |
blood lymphocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
lymphocyte quantity |
male |
70 days
| 6 |
|
70.0 |
% |
2.45 |
6.0 |
automated differential white blood cell count test |
|
|
|
0 |
|
May-Giemsa staining |
|
79833 |
1498 |
SHRSP/Izm |
serum triglyceride level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood triglyceride amount |
male |
91 days
| 5 |
|
57.52 |
mg/dl |
10.62 |
23.75 |
serum triglyceride analysis |
|
0 |
|
0 |
|
|
|
64856 |
115 |
SHRSP/Izm |
serum triglyceride level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood triglyceride amount |
female |
91 days
| 5 |
|
50.44 |
mg/dl |
11.5 |
25.72 |
serum triglyceride analysis |
|
0 |
|
0 |
|
|
|
64859 |
115 |
SHRSP/Izm |
both adrenal glands weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70 days
| 6 |
|
18.6 |
mg/100g |
0.57 |
1.4 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72868 |
41 |
SHRSP/Izm |
body weight |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
body mass |
male |
150 days
| 17 |
|
315.0 |
g |
7.28 |
30.0 |
body weighing method |
|
0 |
|
0 |
|
|
|
65509 |
567 |
SHRSP/Izm |
partial pressure of blood oxygen |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
blood oxygen amount |
male |
150 days
| 5 |
|
119.0 |
mmHg |
4.02 |
9.0 |
automated blood gas analysis |
|
0 |
|
0 |
|
|
|
65512 |
567 |
SHRSP/Izm |
core body temperature |
control condition (for 150 days) |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
body temperature trait |
male |
150 days
| 7 |
|
37.7 |
degrees C |
0.23 |
0.6 |
in vivo thermometry |
|
0 |
|
0 |
|
|
|
65962 |
567 |
SHRSP/Izm |
body weight |
control condition (0 null) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
body mass |
female |
91 days
| 5 |
|
160.6 |
g |
3.6 |
8.05 |
body weighing method |
|
0 |
|
0 |
|
|
|
64831 |
115 |
SHRSP/Izm |
plasma glucose level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood glucose amount |
male |
91 days
| 5 |
|
141.84 |
mg/dl |
4.32 |
9.66 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
64868 |
115 |
SHRSP/Izm |
plasma glucose level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood glucose amount |
female |
91 days
| 5 |
|
134.46 |
mg/dl |
13.14 |
29.38 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
64871 |
115 |
SHRSP/Izm |
core body temperature |
control condition (between 70 and 84 days) |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
body temperature trait |
male |
70 days-84 days |
8 |
|
37.4 |
degrees C |
0.11 |
0.3 |
in vivo thermometry |
|
0 |
|
0 |
|
|
|
65954 |
567 |
SHRSP/Izm |
urine vanillylmandelic acid excretion rate |
cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine vanillylmandelic acid amount |
not specified |
0 days
| 6 |
|
2700.0 |
pmol/4h |
40.82 |
100.0 |
high-performance liquid chromatography |
|
0.0 |
|
0 |
|
hplc |
urine vanillylmandelic acid exretion rate |
68661 |
971 |
SHRSP/Izm |
hematocrit |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70 days
| 6 |
|
54.6 |
% |
1.43 |
3.5 |
automated cell/particle size/count analysis method |
|
|
|
0 |
|
Sysmex, F-800 type |
|
79802 |
1498 |
SHRSP/Izm |
white blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70 days
| 6 |
|
2.5 |
x 1000 cells/ul |
0.33 |
0.8 |
automated cell/particle size/count analysis method |
|
|
|
0 |
|
Sysmex, F-800 type |
|
79806 |
1498 |
SHRSP/Izm |
prothrombin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70 days
| 6 |
|
16.7 |
s |
0.2 |
0.5 |
automated coagulometer method |
|
|
|
0 |
|
Sysmex, CA-3000 type |
|
79808 |
1498 |
SHRSP/Izm |
plasma albumin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70 days
| 6 |
|
0.4 |
g/l |
0.01 |
0.02 |
automated plasma albumin analysis |
|
|
|
0 |
|
Hitachi, model 7170 |
|
79814 |
1498 |
SHRSP/Izm |
blood eosinophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
eosinophil quantity |
male |
70 days
| 6 |
|
1.0 |
% |
0.41 |
1.0 |
automated differential white blood cell count test |
|
|
|
0 |
|
May-Giemsa staining |
|
79830 |
1498 |
SHRSP/Izm |
absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio |
physical restraint in mechanical restrainer (for 3 hours) |
Xiao B, et al., J Hypertens. 2010 Nov 8. |
heart pumping trait |
male |
91 days
| 5 |
serial mean |
3.39 |
null |
|
|
wire electrode telemetric electrocardiography with power spectral analysis |
|
0.0 |
|
0 |
|
|
avg of 5 measurements for |
84603 |
990 |
SHRSP/Izm |
absolute change in urine norepinephrine level |
cold ambient air exposure (4 degrees C) (for 6 hours) |
Xiao B, et al., J Hypertens. 2010 Nov 8. |
urine norepinephrine amount |
male |
84 days
| 10 |
|
95.33 |
nmol/h |
|
|
high-performance liquid chromatography |
|
0.0 |
|
0 |
|
|
nmol/6h |
84604 |
990 |
SHRSP/Izm |
systolic blood pressure |
controlled visible light exposure |
Xiao B, et al., J Hypertens. 2010 Nov 8. |
arterial blood pressure trait |
male |
94 days
| 0 |
serial mean |
213.0 |
mmHg |
|
31.0 |
radiotelemetry |
|
0.0 |
|
0 |
|
|
avg of 5 measurements for |
84616 |
990 |
SHRSP/Izm |
systolic blood pressure |
controlled exposure to darkness |
Xiao B, et al., J Hypertens. 2010 Nov 8. |
arterial blood pressure trait |
male |
94 days
| 0 |
serial mean |
226.0 |
mmHg |
|
30.0 |
radiotelemetry |
|
0.0 |
|
0 |
|
|
avg of 5 measurements for |
84618 |
990 |
SHRSP/Izm |
lung wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70 days
| 6 |
|
0.91 |
g |
0.02 |
0.06 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72861 |
41 |
SHRSP/Izm |
both kidneys wet weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70 days
| 6 |
|
0.76 |
% |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72866 |
41 |
SHRSP/Izm |
partial pressure of blood carbon dioxide (Pco2) |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
blood carbon dioxide amount |
male |
70 days-84 days |
8 |
|
40.6 |
mmHg |
0.85 |
2.4 |
automated blood gas analysis |
|
0 |
|
0 |
|
|
|
65514 |
567 |
SHRSP/Izm |
systolic blood pressure |
control condition |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
arterial blood pressure trait |
male |
91 days
| 5 |
|
219.6 |
mmHg |
6.8 |
15.21 |
tail cuff plethysmography |
|
|
|
0 |
|
|
|
11678 |
115 |
SHRSP/Izm |
mean arterial blood pressure |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
arterial blood pressure trait |
male |
150 days
| 17 |
|
241.0 |
mmHg |
5.34 |
22.0 |
vascular fluid filled catheter |
right femoral artery |
0 |
|
0 |
|
|
|
65293 |
567 |
SHRSP/Izm |
plasma chloride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood chloride amount |
male |
70 days
| 6 |
|
108.0 |
mmol/l |
0.41 |
1.0 |
automated blood electrolyte analysis |
|
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
79828 |
1498 |
SHRSP/Izm |
systolic blood pressure |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
arterial blood pressure trait |
male |
56 days-70 days |
6 |
serial mean |
190.0 |
mmHg |
4.49 |
11.0 |
tail cuff photoplethysmography |
|
|
|
0 |
|
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
75183 |
14 |
SHRSP/Izm |
blood pH |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
blood acidity-alkalinity balance trait |
male |
150 days
| 7 |
|
7.44 |
null |
0.01 |
0.03 |
blood pH analysis |
|
0 |
|
0 |
|
|
|
65529 |
567 |
SHRSP/Izm |
percentage of study population developing cerebrovascular lesions during a period of time |
controlled sodium content drinking water (1 %) (for 14 days) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
cerebrovascular system integrity trait |
female |
98 days
| 10 |
|
0.0 |
% |
|
|
ex vivo light microscopy |
MA:0000168 |
0 |
|
0 |
|
|
|
65292 |
115 |
SHRSP/Izm |
urine norepinephrine excretion rate |
room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine norepinephrine amount |
not specified |
0 days
| 6 |
|
3490.0 |
pmol/4h |
506.23 |
1240.0 |
high-performance liquid chromatography |
|
0.0 |
|
0 |
|
hplc |
absolute change in urine norepinephrine excretion rate |
68658 |
971 |
SHRSP/Izm |
urine vanillylmandelic acid excretion rate |
room temperature (for 4 hours) then cold ambient air exposure (4 degrees C) (for 4 hours) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
urine vanillylmandelic acid amount |
not specified |
0 days
| 6 |
|
1660.0 |
pmol/4h |
93.9 |
230.0 |
high-performance liquid chromatography |
|
0.0 |
|
0 |
|
hplc |
urine vanillylmandelic acid exretion rate |
68664 |
971 |
SHRSP/Izm |
mean arterial blood pressure |
control condition |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
arterial blood pressure trait |
male |
98 days
| 6 |
|
175.0 |
mmHg |
6.0 |
14.7 |
vascular indwelling catheter method |
|
0.0 |
|
0 |
|
|
|
69085 |
1120 |
SHRSP/Izm |
heart rate |
control condition |
Yamazato M, et al., Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R709-14. Epub 2005 Oct 20. |
heart pumping trait |
male |
98 days
| 6 |
|
287.0 |
beats/min |
5.0 |
12.25 |
vascular indwelling catheter method |
|
0.0 |
|
0 |
|
|
|
69088 |
1120 |
SHRSP/Izm |
mean corpuscular hemoglobin concentration |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
30.9 |
g/dl |
0.78 |
1.9 |
automated cell/particle size/count analysis method |
|
|
|
0 |
|
Sysmex, F-800 type |
|
79805 |
1498 |
SHRSP/Izm |
plasma total bilirubin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood bilirubin amount |
male |
70 days
| 6 |
|
0.05 |
mg/dl |
0.0 |
0.01 |
automated plasma analysis |
|
|
|
0 |
|
PMID:15591307 |
total plasma bilirubin level |
79821 |
1498 |
SHRSP/Izm |
blood basophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
basophil quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
|
0 |
|
May-Giemsa staining |
|
79829 |
1498 |
SHRSP/Izm |
blood segmented neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70 days
| 6 |
|
29.0 |
% |
2.04 |
5.0 |
automated differential white blood cell count test |
|
|
|
0 |
|
May-Giemsa staining |
segmented neutrophil % |
79832 |
1498 |
SHRSP/Izm |
blood monocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
monocyte quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
|
0 |
|
May-Giemsa staining |
|
79834 |
1498 |
SHRSP/Izm |
urine sodium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63 days
| 6 |
|
0.01 |
uEq/min/g |
0.0 |
0.0 |
automated urine analysis |
|
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
95527 |
1662 |
SHRSP/Izm |
urine chloride level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63 days
| 6 |
|
155.0 |
mEq/L |
11.02 |
27.0 |
automated urine analysis |
|
|
|
0 |
|
|
|
95530 |
1662 |
SHRSP/Izm |
brain weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70 days
| 6 |
|
0.83 |
% |
0.02 |
0.04 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72858 |
41 |
SHRSP/Izm |
liver weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70 days
| 6 |
|
2.91 |
% |
0.04 |
0.09 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72864 |
41 |
SHRSP/Izm |
both adrenal glands wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70 days
| 6 |
|
41.6 |
mg |
1.1 |
2.7 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72867 |
41 |
SHRSP/Izm |
both testes wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70 days
| 6 |
|
2.71 |
g |
0.08 |
0.19 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
0 |
|
|
|
72871 |
41 |
SHRSP/Izm |
blood pH |
control condition |
Yao H, et al., Physiol Genomics. 2007 Feb 27;. |
blood acidity-alkalinity balance trait |
male |
70 days-84 days |
8 |
|
7.4 |
null |
0.01 |
0.02 |
blood pH analysis |
|
0 |
|
0 |
|
|
|
65528 |
567 |
SHRSP/Izm |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
70 days
| 6 |
|
236.2 |
g |
3.96 |
9.7 |
whole body digital scale |
|
|
|
0 |
|
|
|
70928 |
21 |
SHRSP/Izm |
blood hemoglobin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
16.8 |
g/dl |
0.12 |
0.3 |
automated cell/particle size/count analysis method |
|
|
|
0 |
|
Sysmex, F-800 type |
|
79801 |
1498 |
SHRSP/Izm |
mean corpuscular hemoglobin |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
17.7 |
pg |
0.16 |
0.4 |
automated cell/particle size/count analysis method |
|
|
|
0 |
|
Sysmex, F-800 type |
|
79804 |
1498 |
SHRSP/Izm |
plasma total cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood cholesterol amount |
male |
70 days
| 6 |
|
60.0 |
mg/dl |
2.45 |
6.0 |
automated plasma analysis |
|
|
|
0 |
|
PMID:15591307 |
|
79817 |
1498 |
SHRSP/Izm |
blood band neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
|
0 |
|
May-Giemsa staining |
band neutrophil % |
79831 |
1498 |