Phenominer Database Results (58 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
F344/NRrrc blood neutrophil count control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 neutrophil quantity both 132.0 days-139.0 days 216 4.06 x 1000 cells/ul 0.29 4.2 automated differential white blood cell count test 0 65876 114
F344/NRrrc blood hemoglobin level control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 blood hemoglobin amount both 132.0 days-139.0 days 208 17.0 g/dl 0.03 0.5 automated blood cell counting method 0 65919 114
F344/NRrrc white blood cell count control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 leukocyte quantity both 132.0 days-139.0 days 208 6.1 x 1000 cells/ul 0.07 1.0 automated total white blood cell count test 0 65943 114
F344/NRrrc blood glucose level glucose solution (2 g/kg) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 blood glucose amount both 118.0 days-125.0 days 220 123.12 mg/dl 0.81 12.06 intraperitoneal glucose tolerance test 0 glucose injection min 65948 114
F344/NRrrc body weight control condition Tanomura H, et al., J Vet Med Sci 2002 Jan;64(1):45-50. body mass male 245.0 days 7 375.6 g 7.56 20.0 body weighing method 12202 234
F344/NRrrc body weight fasting (for 18 hours) Ogino T, et al., Mamm Genome 2003 Dec;14(12):839-44. body mass male 246.0 days 21 641.0 g 7.25 33.21 body weighing method 12378 248
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male  days 5 15.1 % 1.1 2.46 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 224 days remodeling/total ratio 69147 950
F344/NRrrc liver tumorous lesion number to liver area ratio controlled 3-methyl-4'-dimethylaminoazobenzene content diet (0.06 %) (for 49 days) Yan Y, et al., Carcinogenesis 2002 Jan;23(1):189-96. liver integrity trait not specified 84.0 days 8 120.0 /cm2 4.95 14.0 ex vivo light microscopy with digital image analysis 0.0 8 wks in text, inconsistent 68157 890
F344/NRrrc total surface area of liver occupied by tumorous lesions controlled 3-methyl-4'-dimethylaminoazobenzene content diet (0.06 %) (for 140 days) Yan Y, et al., Carcinogenesis 2002 Jan;23(1):189-96. liver integrity trait not specified 175.0 days 11 67.5 mm2 9.38 31.1 ex vivo slide caliper method 0.0 slide caliper total area of tumors 69942 890
F344/NRrrc plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 blood glucose amount male 210.0 days 7 124.1 mg/dl 1.6 4.23 oral glucose tolerance test 0.0 oral glucose 30 min 68073 836
F344/NRrrc plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 blood glucose amount male 210.0 days 7 139.0 mg/dl 2.4 6.35 oral glucose tolerance test 0.0 oral glucose 90 min 68079 836
F344/NRrrc plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 blood glucose amount male 210.0 days 7 128.0 mg/dl 2.4 6.35 oral glucose tolerance test 0.0 oral glucose 120 min 68082 836
F344/NRrrc ratio of apoptotic bodies to intact tumor cells in remodelling liver tumorous lesions N-nitrosodiethylamine (150 mg/kg) then controlled protein content diet (for 15 days) and controlled 2-acetamidofluorene content diet (0.02 %) then partial hepatectomy De Miglio MR, et al., Int J Cancer 2003 May 20;105(1):70-5. liver integrity trait not specified  days 5 1.51 % 0.07 0.16 ex vivo light microscopy with immunohistochemistry and digital image analysis 0.0 84787 1603
F344/NRrrc blood CD8 cell count control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 CD8-positive T cell quantity both 132.0 days-139.0 days 200 0.85 x 10E6 cells/ml 0.01 0.14 automated differential white blood cell count test 0 65887 114
F344/NRrrc blood CD25 cell count to CD4 cell count ratio control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 regulatory T cell quantity both 132.0 days-139.0 days 215 47.75 % 1.23 18.1 automated differential white blood cell count test 0 65904 114
F344/NRrrc red blood cell count control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 erythrocyte quantity both 132.0 days-139.0 days 208 9.52 x 10E6 cells/ul 0.02 0.27 automated blood cell counting method 0 65937 114
F344/NRrrc serum leptin level fasting (for 18 hours) Ogino T, et al., Mamm Genome 2003 Dec;14(12):839-44. blood leptin amount male 246.0 days 21 6.83 ng/ml 0.24 1.09 enzyme linked immunosorbent assay carotid artery 0 immunoreactive leptin kit; Morinaga Institute of Biological Science, Yokohama, Japan 65740 248
F344/NRrrc both adrenal glands weight to body weight ratio control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 adrenal gland mass both 167.0 days-174.0 days 210 21.1 mg/100g 0.09 1.3 post excision weight measurement 0 65996 114
F344/NRrrc intramuscular fat area control condition Tanomura H, et al., J Vet Med Sci 2002 Jan;64(1):45-50. intramuscular adipose amount male 245.0 days 7 1.34 mm2 0.14 0.38 ex vivo light microscopy with digital image analysis 0.0 67223 234
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy then 5-bromo-2'-deoxyuridine (50 mg/kg) (for 2 hours) Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male  days 5 1070.0 % 143.0 319.76 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 56 days 69143 950
F344/NRrrc benign liver tumor number N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male  days 16 22.3 null 2.0 8.0 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 490 days 69151 950
F344/NRrrc malignant liver tumor number N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male  days 16 2.2 null 0.2 0.8 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 490 days check malignant 69153 950
F344/NRrrc plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 blood glucose amount male 210.0 days 7 104.0 mg/dl 6.1 16.14 oral glucose tolerance test 0.0 oral glucose min 68070 836
F344/NRrrc liver ornithine decarboxylase activity controlled 3-methyl-4'-dimethylaminoazobenzene content diet (0.06 %) (for 140 days) Yan Y, et al., Carcinogenesis 2002 Jan;23(1):189-96. liver ornithine decarboxylase activity trait not specified 175.0 days 11 28.3 pmol/mg/h 3.29 10.9 liquid scintillation counting pmole/mg/hour 69940 890
F344/NRrrc serum alpha-fetoprotein level controlled 3-methyl-4'-dimethylaminoazobenzene content diet (0.06 %) (for 140 days) Yan Y, et al., Carcinogenesis 2002 Jan;23(1):189-96. serum alpha-fetoprotein amount not specified 175.0 days 11 2732.0 ng/ml 97.99 325.0 blood protein analysis 0.0 69939 890
F344/NRrrc hematocrit control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 erythrocyte quantity both 132.0 days-139.0 days 208 51.9 % 0.15 2.2 automated blood cell counting method 0 65913 114
F344/NRrrc platelet count control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 platelet quantity both 132.0 days-139.0 days 208 812.0 x 1000 /ul 1.66 24.0 automated blood cell counting method 0 65931 114
F344/NRrrc serum triglyceride level fasting (for 18 hours) Ogino T, et al., Mamm Genome 2003 Dec;14(12):839-44. blood triglyceride amount male 246.0 days 21 131.8 mg/dl 4.52 20.72 serum triglyceride analysis carotid artery Triglyceride E-test Wako, Wako Pure Chemical Industries, Ltd, Osaka, Japan 12376 248
F344/NRrrc heart weight to body weight ratio control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 heart mass both 167.0 days-174.0 days 45 3.36 g/kg 0.04 0.28 post excision weight measurement 0 66004 114
F344/NRrrc intramuscular fat area to body weight ratio control condition Tanomura H, et al., J Vet Med Sci 2002 Jan;64(1):45-50. intramuscular adipose amount male 245.0 days 7 3.62 (mm2/g)/1000 0.83 2.19 ex vivo light microscopy with digital image analysis 0.0 67225 234
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male  days 9 13.8 % 0.8 2.4 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 56 days remodeling/total ratio 69145 950
F344/NRrrc body weight control condition Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 body mass male 210.0 days 7 374.1 g 8.0 21.17 body weighing method 0.0 68067 836
F344/NRrrc liver tumorous lesion number controlled 3-methyl-4'-dimethylaminoazobenzene content diet (0.06 %) (for 140 days) Yan Y, et al., Carcinogenesis 2002 Jan;23(1):189-96. liver integrity trait not specified 175.0 days 11 6.5 null 0.27 0.9 ex vivo light microscopy with digital image analysis 0.0 68166 890
F344/NRrrc liver tumorous lesion number N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait female  days 3 1424.0 null 242.0 419.16 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 56 days 68617 950
F344/NRrrc plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 blood glucose amount male 210.0 days 7 185.5 mg/dl 4.0 10.58 oral glucose tolerance test 0.0 oral glucose 60 min 68076 836
F344/NRrrc ratio of apoptotic bodies to intact tumor cells in nonremodelling liver tumorous lesions N-nitrosodiethylamine (150 mg/kg) then controlled protein content diet (for 15 days) and controlled 2-acetamidofluorene content diet (0.02 %) then partial hepatectomy De Miglio MR, et al., Int J Cancer 2003 May 20;105(1):70-5. liver integrity trait not specified  days 5 1.25 % 0.05 0.11 ex vivo light microscopy with immunohistochemistry and digital image analysis 0.0 84785 1603
F344/NRrrc blood monocyte count control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 monocyte quantity both 132.0 days-139.0 days 202 0.99 x 1000 cells/ul 0.11 1.51 automated differential white blood cell count test 0 65879 114
F344/NRrrc blood CD4 cell count control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 CD4-positive T cell quantity both 132.0 days-139.0 days 203 1.39 x 1000 cells/ul 0.01 0.2 automated differential white blood cell count test 0 65883 114
F344/NRrrc blood CD4 cell count to CD8 cell count ratio control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 CD4-positive T cell quantity both 132.0 days-139.0 days 211 181.0 % 2.27 33.0 automated differential white blood cell count test 0 65891 114
F344/NRrrc blood CD25 cell count to CD8 cell count ratio control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 regulatory T cell quantity both 132.0 days-139.0 days 215 71.5 % 1.9 27.9 automated cell/particle size/count analysis method 0 65907 114
F344/NRrrc mean corpuscular volume control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 erythrocyte size trait both 132.0 days-139.0 days 208 54.6 fl 0.08 1.2 automated blood cell counting method 0 65925 114
F344/NRrrc blood glucose level glucose solution (2 g/kg) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 blood glucose amount both 118.0 days-125.0 days 220 249.12 mg/dl 5.16 76.5 intraperitoneal glucose tolerance test 0 glucose injection 30 min 65977 114
F344/NRrrc blood glucose level glucose solution (2 g/kg) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 blood glucose amount both 118.0 days-125.0 days 220 158.4 mg/dl 1.09 16.2 intraperitoneal glucose tolerance test 0 glucose injection 120 min 65983 114
F344/NRrrc body weight control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 body mass both 70.0 days 220 233.2 g 0.55 8.2 body weighing method 0 66013 114
F344/NRrrc percentage of study population developing malignant liver tumors during a period of time N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male  days 16 100.0 % 5.4 21.6 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 490 days check malignant 69152 950
F344/NRrrc area of individual liver tumorous lesion controlled 3-methyl-4'-dimethylaminoazobenzene content diet (0.06 %) (for 49 days) Yan Y, et al., Carcinogenesis 2002 Jan;23(1):189-96. liver integrity trait not specified 84.0 days 8 0.13 mm2 0.01 0.04 ex vivo light microscopy with digital image analysis 0.0 8 wks in text, inconsistent 68159 890
F344/NRrrc percentage of study population developing liver tumors during a period of time controlled 3-methyl-4'-dimethylaminoazobenzene content diet (0.06 %) (for 140 days) Yan Y, et al., Carcinogenesis 2002 Jan;23(1):189-96. liver integrity trait not specified 175.0 days 11 100.0 % necropsy 0.0 liver tumor incidence 68164 890
F344/NRrrc volume of liver occupied by tumorous lesions as percentage of total liver volume N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait female  days 3 8.92 % 2.85 4.94 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 56 days 68619 950
F344/NRrrc white blood cell count control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 leukocyte quantity both 132.0 days-139.0 days 207 16.33 x 1000 cells/ul 1.17 16.8 automated total white blood cell count test 0 65872 114
F344/NRrrc systolic blood pressure control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 arterial blood pressure trait both 125.0 days-132.0 days 220 149.0 mmHg 1.08 16.0 tail cuff piezoplethysmography 6-8 readings per sitting 11677 114
F344/NRrrc serum total cholesterol level fasting (for 18 hours) Ogino T, et al., Mamm Genome 2003 Dec;14(12):839-44. blood cholesterol amount male 246.0 days 21 56.33 mg/dl 2.29 10.5 serum total cholesterol measurement test carotid artery Cholesterol E-test Wako, Wako Pure Chemical Industries, Ltd, Osaka, Japan 12371 248
F344/NRrrc both adrenal glands wet weight control condition Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 adrenal gland mass both 167.0 days-174.0 days 210 45.7 mg 0.15 2.2 post excision weight measurement 0 65990 114
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male  days 5 30.4 % 2.7 6.04 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 105 days remodeling/total ratio 69146 950
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male  days 3 40.6 % 5.4 9.35 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 224 days remodeling/total ratio 69149 950
F344/NRrrc percentage of study population developing benign liver tumors during a period of time N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male  days 16 100.0 % 5.4 21.6 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 490 days benign liver tumor incidence 69150 950
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male  days 3 19.2 % 2.8 4.85 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 56 days 69148 950
F344/NRrrc area of liver occupied by tumorous lesions as percentage of total liver area controlled 3-methyl-4'-dimethylaminoazobenzene content diet (0.06 %) (for 49 days) Yan Y, et al., Carcinogenesis 2002 Jan;23(1):189-96. liver integrity trait not specified 84.0 days 8 15.2 % 1.59 4.5 ex vivo light microscopy with digital image analysis 0.0 8 wks in text, inconsistent % tumorous foci area in liver 68162 890
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled protein content diet (for 15 days) and 2-acetamidofluorene (0.02 %) (for 15 days) then partial hepatectomy (for 202.5 days) De Miglio MR, et al., Int J Cancer 2004 Aug 10;111(1):9-16. liver integrity trait male  days 10 19.0 % ex vivo light microscopy with digital image analysis liver 0.0 224 days 70204 1302