BBDR/Rhw |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (2 ml) (for 28 days) and Poly I:C (5 ug/g) (for 28 days) |
Martin AM, et al., Diabetes 1999 Nov;48(11):2138-44 |
glucose metabolism trait |
not specified |
0 days-70 days |
12 |
100.0 |
% |
|
|
blood glucose analysis |
|
0.0 |
injection |
0 |
|
anti-RT6.1mAB and poly I:C |
|
66147 |
711 |
BBDR/Rhw |
post-insult time to onset of diabetes mellitus |
anti-RT6.1 antibody (2 ml) (for 28 days) and Poly I:C (5 ug/g) (for 28 days) |
Martin AM, et al., Diabetes 1999 Nov;48(11):2138-44 |
glucose metabolism trait |
not specified |
0 days-70 days |
12 |
11.0 |
d |
1.0 |
3.46 |
blood glucose analysis |
|
0.0 |
injection |
0 |
|
anti-RT6.1mAB and poly I:C |
|
66148 |
711 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
185 days
| 10 |
102.6 |
mg/dl |
1.8 |
5.69 |
blood glucose analysis |
tail vein |
|
|
0 |
|
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11480 |
85 |
SS/Jr |
plasma glucose level |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
blood glucose amount |
male |
114 days-118 days |
4 |
142.2 |
mg/dl |
19.8 |
39.6 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
65092 |
283 |
SS.SR-(D3Arb14-D3Mco36)/Mco |
plasma glucose level |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
blood glucose amount |
male |
114 days-118 days |
6 |
124.2 |
mg/dl |
3.6 |
8.82 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
65093 |
283 |
WF.BBDR-(D4Got39-D4Rat44)/Wor |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
10 |
30.0 |
% |
|
|
blood glucose analysis |
|
0.0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
incidence of experimental diabetes mellitus |
66154 |
714 |
WF.BBDR-(D4Got39-D4Rat44)/Wor |
post-insult time to onset of diabetes mellitus |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
10 |
17.0 |
d |
|
|
blood glucose analysis |
|
0.0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
onset of experimental diabetes mellitus |
66156 |
714 |
WF.BBDR-(D4Rat96-D4Rat44)/Wor |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (for 30 days) and Poly I:C (2.5 ug/g) (for 30 days) |
Blankenhorn EP, et al., Ann N Y Acad Sci. 2007 Mar 21;. |
glucose metabolism trait |
not specified |
68 days-72 days |
0 |
58.0 |
% |
|
|
blood glucose analysis |
|
0.0 |
injection |
0 |
|
|
|
66166 |
715 |
BBDP.WF-(D8Rat73-D8Sunn1467)(D13Rat124-D13Mgh5)/Sunn |
percentage of study population developing type 1 diabetes mellitus during a period of time |
control condition |
Wallis RH, et al., Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27 |
glucose metabolism trait |
not specified |
60 days-120 days |
36 |
31.0 |
% |
|
|
blood glucose analysis |
pancreas |
0.0 |
|
0 |
|
|
|
68168 |
891 |
BBDP.WF-(D8Rat73-D8Rat121)/Sunn |
percentage of study population developing type 1 diabetes mellitus during a period of time |
control condition |
Wallis RH, et al., Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27 |
glucose metabolism trait |
not specified |
60 days-120 days |
54 |
80.0 |
% |
|
|
blood glucose analysis |
pancreas |
0.0 |
|
0 |
|
|
|
68190 |
891 |
BBDP.WF-(D8Rat16-D8Sunn1467)/Sunn |
percentage of study population developing type 1 diabetes mellitus during a period of time |
control condition |
Wallis RH, et al., Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27 |
glucose metabolism trait |
not specified |
60 days-120 days |
43 |
33.0 |
% |
|
|
blood glucose analysis |
pancreas |
0.0 |
|
0 |
|
|
|
68191 |
891 |
Crl:SD |
blood glucose level |
controlled ethanol content drinking water (1 %) (for 63 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
blood glucose amount |
female |
98 days
| 12 |
82.8 |
mg/dl |
4.1 |
14.22 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
week one |
75791 |
1538 |
GK/Jcl |
blood glucose level |
standard diet |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
blood glucose amount |
male |
84 days
| 8 |
478.26 |
mg/dl |
23.74 |
67.14 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103073 |
2785 |
GK/Jcl |
blood glucose level |
Omacor (400 mg/kg/d) (for 56 days) |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
blood glucose amount |
male |
84 days
| 8 |
388.26 |
mg/dl |
27.37 |
77.4 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103074 |
2785 |
LL/Mav |
blood glucose level |
streptozotocin (100 mg/kg) then fasting (for 16 hours) then glucose (2 g/kg) (for 1 hours) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
blood glucose amount |
male |
56 days
| 18 |
337.0 |
mg/dl |
10.0 |
42.43 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102719 |
2721 |
GK/MolTac |
blood glucose level |
running on treadmill (0-10 m/min) (between 0.1 and 0.2 hours) then controlled saxagliptin content diet (10 mg/kg/d) (for 12 days) then running on treadmill (15 m/min) (for 0.5 hours) then running on treadmill (15 m/min) (for 0.8 hours) |
Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. |
blood glucose amount |
male |
144 days
| 12 |
289.0 |
mg/dl |
29.0 |
100.46 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103995 |
2885 |
SD |
blood glucose level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood glucose amount |
male |
140 days
| 6 |
138.6 |
mg/dl |
10.3 |
25.23 |
blood glucose analysis |
|
0.0 |
unx |
84 |
days |
|
|
100124 |
2419 |
LL/Mav |
blood glucose level |
vehicle control condition then fasting (for 16 hours) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
blood glucose amount |
male |
56 days
| 9 |
70.0 |
mg/dl |
1.0 |
3.0 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102714 |
2721 |
LH/Mav |
blood glucose level |
streptozotocin (75 mg/kg) then fasting (for 16 hours) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood glucose amount |
male |
49 days-56 days |
37 |
70.0 |
mg/dl |
1.0 |
6.08 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102658 |
2703 |
SS-Adora2bem2Mcwi |
blood glucose level |
fasting (for 12 hours) |
Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. |
blood glucose amount |
male |
140 days-168 days |
8 |
96.0 |
mg/dl |
2.0 |
5.66 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
105865 |
3023 |
W/Kyo |
blood glucose level |
running on treadmill (15 m/min) (for 1 hours) |
Kondo H, etal., Muscle Nerve. 2015 Mar;51(3):391-9. doi: 10.1002/mus.24316. Epub 2015 Jan 6. |
blood glucose amount |
male |
63 days
| 6 |
102.6 |
mg/dl |
1.8 |
4.41 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
108043 |
3110 |
GK |
blood glucose level |
running on treadmill (15 m/min) (for 1 hours) |
Kondo H, etal., Muscle Nerve. 2015 Mar;51(3):391-9. doi: 10.1002/mus.24316. Epub 2015 Jan 6. |
blood glucose amount |
male |
63 days
| 6 |
268.2 |
mg/dl |
23.4 |
57.32 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
108045 |
3110 |
HanTac:WH |
blood glucose level |
control condition |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
56 days
| 8 |
108.0 |
mg/dl |
1.8 |
5.09 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110261 |
3168 |
GK/MolTac |
blood glucose level |
control condition |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
56 days
| 10 |
127.8 |
mg/dl |
1.8 |
5.69 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110264 |
3168 |
GK/MolTac |
blood glucose level |
anti-rh-VEGF165 monoclonal antibody (1 mg) (for 28 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
84 days
| 10 |
129.6 |
mg/dl |
1.8 |
5.69 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110272 |
3168 |
WF.BBDR-(D4Got51-D4Rat44)/Wor |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
12 |
0.0 |
% |
|
|
blood glucose analysis |
|
0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
|
66155 |
714 |
WF.BBDR-(D4Rat93-D4Rat228)/Wor |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (for 30 days) and Poly I:C (2.5 ug/g) (for 30 days) |
Blankenhorn EP, et al., Ann N Y Acad Sci. 2007 Mar 21;. |
glucose metabolism trait |
not specified |
68 days-72 days |
0 |
52.0 |
% |
|
|
blood glucose analysis |
|
0 |
injection |
0 |
|
|
|
66168 |
715 |
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco |
plasma glucose level |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
blood glucose amount |
male |
114 days-118 days |
6 |
142.2 |
mg/dl |
7.2 |
17.64 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
65094 |
283 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
185 days
| 10 |
111.6 |
mg/dl |
1.8 |
5.69 |
blood glucose analysis |
tail vein |
|
|
0 |
|
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11481 |
85 |
Crl:WI |
blood glucose level |
control condition then controlled saxagliptin content diet (10 mg/kg/d) (for 12 days) |
Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. |
blood glucose amount |
male |
144 days
| 6 |
153.0 |
mg/dl |
7.0 |
17.15 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103989 |
2885 |
WF.BBDR-(D4Rat96-D4Rat44)/Wor |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
12 |
58.0 |
% |
|
|
blood glucose analysis |
|
0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
|
66157 |
714 |
WF.BBDR-(D4Arb29-D4Rat44)/Wor |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
18 |
39.0 |
% |
|
|
blood glucose analysis |
|
0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
|
66159 |
714 |
WF.BBDR-(D4Rat16-D4Got39)/Wor |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
4 |
0.0 |
% |
|
|
blood glucose analysis |
|
0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
|
66160 |
714 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
185 days
| 9 |
102.6 |
mg/dl |
1.8 |
5.4 |
blood glucose analysis |
tail vein |
|
|
0 |
|
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11479 |
85 |
BBDP.WF-(D8Rat73-D8Sunn1467)/Sunn |
percentage of study population developing type 1 diabetes mellitus during a period of time |
control condition |
Wallis RH, et al., Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27 |
glucose metabolism trait |
not specified |
60 days-120 days |
61 |
41.0 |
% |
|
|
blood glucose analysis |
pancreas |
0.0 |
|
0 |
|
|
|
68187 |
891 |
BBDP.WF-(D13Rat124-D13Mgh5)/Sunn |
percentage of study population developing type 1 diabetes mellitus during a period of time |
control condition |
Wallis RH, et al., Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27 |
glucose metabolism trait |
not specified |
60 days-120 days |
40 |
82.0 |
% |
|
|
blood glucose analysis |
pancreas |
0.0 |
|
0 |
|
|
|
68193 |
891 |
Crl:SD |
blood glucose level |
controlled fructose content drinking water (5 %) (for 63 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 63 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
blood glucose amount |
female |
98 days
| 12 |
81.0 |
mg/dl |
2.34 |
8.1 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
week one |
75793 |
1538 |
Jcl:WI |
blood glucose level |
standard diet |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
blood glucose amount |
male |
84 days
| 8 |
162.36 |
mg/dl |
16.1 |
45.54 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103071 |
2785 |
Jcl:WI |
blood glucose level |
Omacor (400 mg/kg/d) (for 56 days) |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
blood glucose amount |
male |
84 days
| 8 |
145.44 |
mg/dl |
15.08 |
42.66 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103072 |
2785 |
LL/Mav |
blood glucose level |
vehicle control condition then fasting (for 16 hours) then glucose (2 g/kg) (for 1 hours) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
blood glucose amount |
male |
56 days
| 9 |
136.0 |
mg/dl |
4.0 |
12.0 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102718 |
2721 |
LH/MavRrrcAek |
blood glucose level |
controlled sodium content diet (0.3 %) (for 105 days) then controlled sodium content diet (4 %) (for 21 days) |
Ma MCJ, et al., PLoS One. 2017 Aug 8;12(8):e0182650. doi: 10.1371/journal.pone.0182650. eCollection 2017. |
blood glucose amount |
male |
126 days
| 20 |
88.0 |
mg/dl |
3.4 |
15.21 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102778 |
2722 |
SD |
blood glucose level |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
343.0 |
mg/dl |
18.38 |
52.0 |
blood glucose analysis |
|
0.0 |
stz |
154 |
days |
|
|
99897 |
2358 |
Crl:WI |
blood glucose level |
control condition |
Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. |
blood glucose amount |
male |
144 days
| 6 |
170.0 |
mg/dl |
16.0 |
39.19 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103987 |
2885 |
LL/Mav |
blood glucose level |
streptozotocin (100 mg/kg) then fasting (for 16 hours) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
blood glucose amount |
male |
56 days
| 18 |
71.0 |
mg/dl |
1.0 |
4.24 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102715 |
2721 |
GK/MolTac |
blood glucose level |
control condition then controlled saxagliptin content diet (10 mg/kg/d) (for 12 days) |
Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. |
blood glucose amount |
male |
144 days
| 12 |
305.0 |
mg/dl |
18.0 |
62.35 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103994 |
2885 |
SDT/Jcl |
blood glucose level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood glucose amount |
male |
140 days
| 6 |
140.0 |
mg/dl |
6.8 |
16.66 |
blood glucose analysis |
|
0.0 |
unx |
84 |
days |
|
|
100119 |
2419 |
SDT/Jcl |
blood glucose level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood glucose amount |
male |
140 days
| 7 |
143.1 |
mg/dl |
5.5 |
14.55 |
blood glucose analysis |
|
0.0 |
unx |
84 |
days |
|
|
100121 |
2419 |
GK/CskCrljCrl |
blood glucose level |
control condition |
Wakuta M, etal., Invest Ophthalmol Vis Sci. 2007 Feb;48(2):590-6. doi: 10.1167/iovs.05-1168. |
blood glucose amount |
male |
91 days-105 days |
6 |
259.0 |
mg/dl |
22.45 |
55.0 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
107993 |
3106 |
W/Kyo |
blood glucose level |
control condition |
Kondo H, etal., Muscle Nerve. 2015 Mar;51(3):391-9. doi: 10.1002/mus.24316. Epub 2015 Jan 6. |
blood glucose amount |
male |
63 days
| 6 |
118.8 |
mg/dl |
7.2 |
17.64 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
108042 |
3110 |
HanTac:WH |
blood glucose level |
anti-rh-VEGF165 monoclonal antibody (1 mg) (for 28 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
84 days
| 8 |
111.6 |
mg/dl |
3.6 |
10.18 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110270 |
3168 |
SHRSP.WKY-(Klk1-D1Rat116)/Izm |
plasma glucose level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood glucose amount |
female |
91 days
| 5 |
191.7 |
mg/dl |
9.0 |
20.12 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
64872 |
115 |
LH/Mav |
blood glucose level |
vehicle control condition then fasting (for 16 hours) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood glucose amount |
male |
49 days-56 days |
8 |
67.0 |
mg/dl |
1.0 |
2.83 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102657 |
2703 |
SHRSP.WKY-(Klk1-D1Rat116)/Izm |
plasma glucose level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood glucose amount |
male |
91 days
| 5 |
149.04 |
mg/dl |
5.58 |
12.48 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
64869 |
115 |
BBDP.WF-(D8Rat73-D8Rat20)/Sunn |
percentage of study population developing type 1 diabetes mellitus during a period of time |
control condition |
Wallis RH, et al., Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27 |
glucose metabolism trait |
not specified |
60 days-120 days |
50 |
78.0 |
% |
|
|
blood glucose analysis |
pancreas |
0.0 |
|
0 |
|
|
|
68188 |
891 |
BBDP.WF-(D8Rat73-D8Rat90)/Sunn |
percentage of study population developing type 1 diabetes mellitus during a period of time |
control condition |
Wallis RH, et al., Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27 |
glucose metabolism trait |
not specified |
60 days-120 days |
49 |
74.0 |
% |
|
|
blood glucose analysis |
pancreas |
0.0 |
|
0 |
|
|
|
68189 |
891 |
Crl:SD |
blood glucose level |
controlled fructose content drinking water (5 %) (for 63 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 63 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
blood glucose amount |
female |
98 days
| 12 |
79.2 |
mg/dl |
1.87 |
6.48 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
week one |
75794 |
1538 |
Crl:SD |
blood glucose level |
controlled fructose content drinking water (5 %) (for 63 days) and controlled ethanol content drinking water (1 %) (for 63 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
blood glucose amount |
female |
98 days
| 12 |
84.6 |
mg/dl |
3.64 |
12.6 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
week one |
75792 |
1538 |
OLETF |
blood glucose level |
temocapril (3.9 mg/kg/d) (for 84 days) |
Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. |
blood glucose amount |
male |
364 days
| 11 |
182.88 |
mg/dl |
7.38 |
24.48 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
99419 |
2298 |
LH/Mav |
blood glucose level |
streptozotocin (75 mg/kg) then fasting (for 16 hours) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
blood glucose amount |
male |
56 days
| 14 |
72.0 |
mg/dl |
1.0 |
3.74 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102717 |
2721 |
LH/Mav |
blood glucose level |
vehicle control condition then fasting (for 16 hours) then glucose (2 g/kg) (for 1 hours) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
blood glucose amount |
male |
56 days
| 11 |
127.0 |
mg/dl |
3.0 |
9.95 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102720 |
2721 |
Crlj:WI |
blood glucose level |
controlled air oxygen content (21 %) (for 28 days) |
Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. |
blood glucose amount |
male |
16 days
| 6 |
127.8 |
mg/dl |
7.2 |
17.64 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103003 |
2784 |
GK |
blood glucose level |
controlled air oxygen content (21 %) (for 28 days) |
Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. |
blood glucose amount |
male |
16 days
| 5 |
196.2 |
mg/dl |
18.0 |
40.25 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103005 |
2784 |
SS-Nppbem2Mcwi-/- |
blood glucose level |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
blood glucose amount |
male |
252 days
| 6 |
160.3 |
mg/dl |
16.4 |
40.17 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
99753 |
2319 |
GK/MolTac |
blood glucose level |
control condition |
Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. |
blood glucose amount |
male |
144 days
| 6 |
382.0 |
mg/dl |
69.0 |
169.01 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103990 |
2885 |
GK/MolTac |
blood glucose level |
control condition |
Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. |
blood glucose amount |
male |
144 days
| 12 |
352.0 |
mg/dl |
39.0 |
135.1 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103992 |
2885 |
SD |
blood glucose level |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
358.0 |
mg/dl |
20.86 |
59.0 |
blood glucose analysis |
|
0.0 |
stz |
224 |
days |
|
|
99920 |
2358 |
SD |
blood glucose level |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
350.0 |
mg/dl |
19.09 |
54.0 |
blood glucose analysis |
|
0.0 |
stz |
224 |
days |
|
|
99921 |
2358 |
SS/JrHsdMcwi |
blood glucose level |
fasting (for 12 hours) |
Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. |
blood glucose amount |
male |
84 days
| 8 |
114.0 |
mg/dl |
3.0 |
8.49 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
105862 |
3023 |
HanTac:WH |
blood glucose level |
control IgG monoclonal antibody (1 mg) (for 42 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
98 days
| 8 |
99.0 |
mg/dl |
10.8 |
30.55 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110273 |
3168 |
GK/MolTac |
blood glucose level |
control condition |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
56 days
| 9 |
120.6 |
mg/dl |
1.8 |
5.4 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110263 |
3168 |
HanTac:WH |
blood glucose level |
control IgG monoclonal antibody (1 mg) (for 28 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
84 days
| 8 |
102.6 |
mg/dl |
1.8 |
5.09 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110269 |
3168 |
WF.BBDR-(D4Arb29-D4Rat265)/Wor |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
5 |
40.0 |
% |
|
|
blood glucose analysis |
|
0.0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
|
66161 |
714 |
WF.BBDR-(D4Arb29-D4Rat44)/Wor |
post-insult time to onset of diabetes mellitus |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
18 |
20.0 |
d |
|
|
blood glucose analysis |
|
0.0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
|
66165 |
714 |
BBDP.WF-(D8Rat59-D8Sunn1467)/Sunn |
percentage of study population developing type 1 diabetes mellitus during a period of time |
control condition |
Wallis RH, et al., Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27 |
glucose metabolism trait |
not specified |
60 days-120 days |
49 |
33.0 |
% |
|
|
blood glucose analysis |
pancreas |
0.0 |
|
0 |
|
|
|
68192 |
891 |
WKY/Izm |
plasma glucose level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood glucose amount |
male |
91 days
| 5 |
147.06 |
mg/dl |
5.76 |
12.88 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
64870 |
115 |
OLETF |
blood glucose level |
olmesartan medoxomil (3.8 mg/kg/d) (for 84 days) |
Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. |
blood glucose amount |
male |
364 days
| 12 |
188.82 |
mg/dl |
6.84 |
23.69 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
99418 |
2298 |
SD |
blood glucose level |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
334.0 |
mg/dl |
19.8 |
56.0 |
blood glucose analysis |
|
0.0 |
stz |
154 |
days |
|
|
99896 |
2358 |
SS.SR-(D7Mco19-D7Mco7)/Jr |
plasma glucose level |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
blood glucose amount |
male |
114 days-118 days |
3 |
120.6 |
mg/dl |
10.8 |
18.71 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
65095 |
283 |
WF.BBDR-(D4Arb29-D4Rat265)/Wor |
post-insult time to onset of diabetes mellitus |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
5 |
30.0 |
d |
|
|
blood glucose analysis |
|
0.0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
|
66162 |
714 |
WF.BBDR-(D4Arb29-D4Rat96)/Wor |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
10 |
20.0 |
% |
|
|
blood glucose analysis |
|
0.0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
|
66163 |
714 |
SHRSP/Izm |
plasma glucose level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood glucose amount |
male |
91 days
| 5 |
141.84 |
mg/dl |
4.32 |
9.66 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
64868 |
115 |
SHRSP/Izm |
plasma glucose level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood glucose amount |
female |
91 days
| 5 |
134.46 |
mg/dl |
13.14 |
29.38 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
64871 |
115 |
Crl:SD |
blood glucose level |
controlled fructose content drinking water (5 %) (for 63 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 63 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
blood glucose amount |
female |
98 days
| 12 |
81.0 |
mg/dl |
2.75 |
9.54 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
week one |
75795 |
1538 |
LH/Mav |
blood glucose level |
streptozotocin (75 mg/kg) then fasting (for 16 hours) then glucose (2 g/kg) (for 1 hours) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
blood glucose amount |
male |
56 days
| 14 |
358.0 |
mg/dl |
11.0 |
41.16 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102721 |
2721 |
LH-Chr 17LN/Aek |
blood glucose level |
controlled sodium content diet (0.3 %) (for 105 days) then controlled sodium content diet (4 %) (for 21 days) |
Ma MCJ, et al., PLoS One. 2017 Aug 8;12(8):e0182650. doi: 10.1371/journal.pone.0182650. eCollection 2017. |
blood glucose amount |
male |
126 days
| 11 |
98.0 |
mg/dl |
15.3 |
50.74 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102779 |
2722 |
LH.LH-Chr 17LN-(rs199194111-rs105876746)/Aek |
blood glucose level |
controlled sodium content diet (0.3 %) (for 105 days) then controlled sodium content diet (4 %) (for 21 days) |
Ma MCJ, et al., PLoS One. 2017 Aug 8;12(8):e0182650. doi: 10.1371/journal.pone.0182650. eCollection 2017. |
blood glucose amount |
male |
126 days
| 6 |
83.0 |
mg/dl |
6.4 |
15.68 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102780 |
2722 |
Crlj:WI |
blood glucose level |
controlled air oxygen content (5 %) (for 28 days) |
Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. |
blood glucose amount |
male |
16 days
| 7 |
115.2 |
mg/dl |
7.2 |
19.05 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103004 |
2784 |
GK |
blood glucose level |
controlled air oxygen content (5 %) (for 28 days) |
Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. |
blood glucose amount |
male |
16 days
| 7 |
201.6 |
mg/dl |
10.8 |
28.57 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103006 |
2784 |
SS-Nppbem2Mcwi+/+ |
blood glucose level |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
blood glucose amount |
male |
252 days
| 6 |
183.2 |
mg/dl |
37.8 |
92.59 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
99752 |
2319 |
SD |
blood glucose level |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
106.0 |
mg/dl |
4.6 |
13.0 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
99898 |
2358 |
LH/Mav |
blood glucose level |
vehicle control condition then fasting (for 16 hours) then glucose (2 g/kg) (for 1 hours) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood glucose amount |
male |
49 days-56 days |
8 |
121.0 |
mg/dl |
6.0 |
16.97 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102660 |
2703 |
GK/MolTac |
blood glucose level |
running on treadmill (0-10 m/min) (between 0.1 and 0.2 hours) then running on treadmill (15 m/min) (for 0.5 hours) then running on treadmill (15 m/min) (for 0.8 hours) |
Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. |
blood glucose amount |
male |
144 days
| 6 |
290.0 |
mg/dl |
30.0 |
73.48 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103991 |
2885 |
GK/MolTac |
blood glucose level |
running on treadmill (0-10 m/min) (between 0.1 and 0.2 hours) then running on treadmill (15 m/min) (for 0.5 hours) then running on treadmill (15 m/min) (for 0.8 hours) |
Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. |
blood glucose amount |
male |
144 days
| 12 |
282.0 |
mg/dl |
17.0 |
58.89 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103993 |
2885 |
SD |
blood glucose level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood glucose amount |
male |
140 days
| 6 |
134.7 |
mg/dl |
5.9 |
14.45 |
blood glucose analysis |
|
0.0 |
unx |
84 |
days |
|
|
100120 |
2419 |
SD |
blood glucose level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood glucose amount |
male |
140 days
| 8 |
137.7 |
mg/dl |
8.3 |
23.48 |
blood glucose analysis |
|
0.0 |
unx |
84 |
days |
|
|
100122 |
2419 |
SDT/Jcl |
blood glucose level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood glucose amount |
male |
140 days
| 6 |
132.1 |
mg/dl |
12.3 |
30.13 |
blood glucose analysis |
|
0.0 |
unx |
84 |
days |
|
|
100123 |
2419 |
HanTac:WH |
blood glucose level |
control condition |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
56 days
| 8 |
109.8 |
mg/dl |
1.8 |
5.09 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110262 |
3168 |
HanTac:WH |
blood glucose level |
control IgG monoclonal antibody (1 mg) (for 14 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
70 days
| 8 |
108.0 |
mg/dl |
3.6 |
10.18 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110265 |
3168 |
HanTac:WH |
blood glucose level |
anti-rh-VEGF165 monoclonal antibody (1 mg) (for 14 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
70 days
| 8 |
111.6 |
mg/dl |
3.6 |
10.18 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110266 |
3168 |
GK/MolTac |
blood glucose level |
control IgG monoclonal antibody (1 mg) (for 28 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
84 days
| 9 |
127.8 |
mg/dl |
1.8 |
5.4 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110271 |
3168 |
WF.BBDR-(D4Rat96-D4Rat44)/Wor |
post-insult time to onset of diabetes mellitus |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
12 |
24.0 |
d |
|
|
blood glucose analysis |
|
0.0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
|
66158 |
714 |
WKY/Izm |
plasma glucose level |
fasting (0 null) (for 16 hours) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
blood glucose amount |
female |
91 days
| 5 |
207.18 |
mg/dl |
10.44 |
23.34 |
blood glucose analysis |
|
0 |
|
0 |
|
|
|
64875 |
115 |
LL/Mav |
blood glucose level |
vehicle control condition then fasting (for 16 hours) then glucose (2 g/kg) (for 1 hours) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood glucose amount |
male |
49 days-56 days |
13 |
132.0 |
mg/dl |
4.0 |
14.42 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102659 |
2703 |
WF.BBDR-(D4Arb29-D4Rat96)/Wor |
post-insult time to onset of diabetes mellitus |
anti-RT6.1 antibody (1 ml) and Poly I:C (2.5 ug/g) |
Mordes JP, et al., Diabetes 2002 Nov;51(11):3254-62. |
glucose metabolism trait |
not specified |
68 days-72 days |
10 |
30.0 |
d |
|
|
blood glucose analysis |
|
0.0 |
|
0 |
|
anti-ART2.1mAB and poly I:C |
|
66164 |
714 |
WF.BBDR-(D4Got48-D4Got43)/Wor |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (for 30 days) and Poly I:C (2.5 ug/g) (for 30 days) |
Blankenhorn EP, et al., Ann N Y Acad Sci. 2007 Mar 21;. |
glucose metabolism trait |
not specified |
68 days-72 days |
0 |
13.0 |
% |
|
|
blood glucose analysis |
|
0 |
injection |
0 |
|
|
|
66167 |
715 |
WF.BBDR-(Clcn1-D4Rat228)/Wor |
percentage of study population developing type 1 diabetes mellitus during a period of time |
anti-RT6.1 antibody (for 30 days) and Poly I:C (2.5 ug/g) (for 30 days) |
Blankenhorn EP, et al., Ann N Y Acad Sci. 2007 Mar 21;. |
glucose metabolism trait |
not specified |
68 days-72 days |
0 |
0.0 |
% |
|
|
blood glucose analysis |
|
0 |
injection |
0 |
|
|
|
66169 |
715 |
BBDP/WorBrm |
percentage of study population developing type 1 diabetes mellitus during a period of time |
control condition |
Wallis RH, et al., Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27 |
glucose metabolism trait |
not specified |
60 days-120 days |
14 |
86.0 |
% |
|
|
blood glucose analysis |
pancreas |
0.0 |
|
0 |
|
|
|
68167 |
891 |
OLETF |
blood glucose level |
olmesartan medoxomil (0.35 mg/kg/d) (for 84 days) |
Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. |
blood glucose amount |
male |
364 days
| 11 |
189.54 |
mg/dl |
9.72 |
32.24 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
99417 |
2298 |
LETO |
blood glucose level |
control condition (for 84 days) |
Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. |
blood glucose amount |
male |
364 days
| 11 |
135.72 |
mg/dl |
2.7 |
8.95 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
99420 |
2298 |
LH/Mav |
blood glucose level |
vehicle control condition then fasting (for 16 hours) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
blood glucose amount |
male |
56 days
| 11 |
69.0 |
mg/dl |
1.0 |
3.32 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102716 |
2721 |
LL/Mav |
blood glucose level |
vehicle control condition then fasting (for 16 hours) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood glucose amount |
male |
49 days-56 days |
13 |
65.0 |
mg/dl |
1.0 |
3.61 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102656 |
2703 |
Crl:WI |
blood glucose level |
running on treadmill (0-10 m/min) (between 0.1 and 0.2 hours) then running on treadmill (15 m/min) (for 0.5 hours) then running on treadmill (15 m/min) (for 0.8 hours) |
Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. |
blood glucose amount |
male |
144 days
| 6 |
162.0 |
mg/dl |
8.0 |
19.6 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
103988 |
2885 |
SD |
blood glucose level |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
98.0 |
mg/dl |
3.18 |
9.0 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
99922 |
2358 |
SS/JrHsdMcwi |
blood glucose level |
fasting (for 12 hours) |
Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. |
blood glucose amount |
male |
84 days
| 8 |
117.0 |
mg/dl |
2.0 |
5.66 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
105863 |
3023 |
SS/JrHsdMcwi |
blood glucose level |
fasting (for 12 hours) |
Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. |
blood glucose amount |
male |
140 days-168 days |
8 |
102.0 |
mg/dl |
2.0 |
5.66 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
105864 |
3023 |
Crlj:WI |
blood glucose level |
control condition |
Wakuta M, etal., Invest Ophthalmol Vis Sci. 2007 Feb;48(2):590-6. doi: 10.1167/iovs.05-1168. |
blood glucose amount |
male |
91 days-105 days |
5 |
116.0 |
mg/dl |
4.92 |
11.0 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
107994 |
3106 |
GK |
blood glucose level |
control condition |
Kondo H, etal., Muscle Nerve. 2015 Mar;51(3):391-9. doi: 10.1002/mus.24316. Epub 2015 Jan 6. |
blood glucose amount |
male |
63 days
| 6 |
270.0 |
mg/dl |
10.8 |
26.45 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
108044 |
3110 |
GK/MolTac |
blood glucose level |
control IgG monoclonal antibody (1 mg) (for 14 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
70 days
| 9 |
117.0 |
mg/dl |
1.8 |
5.4 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110267 |
3168 |
GK/MolTac |
blood glucose level |
anti-rh-VEGF165 monoclonal antibody (1 mg) (for 14 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
70 days
| 10 |
131.4 |
mg/dl |
7.2 |
22.77 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110268 |
3168 |
GK/MolTac |
blood glucose level |
anti-rh-VEGF165 monoclonal antibody (1 mg) (for 42 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
98 days
| 10 |
115.2 |
mg/dl |
1.8 |
5.69 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110276 |
3168 |
HanTac:WH |
blood glucose level |
anti-rh-VEGF165 monoclonal antibody (1 mg) (for 42 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
98 days
| 8 |
113.4 |
mg/dl |
3.6 |
10.18 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110274 |
3168 |
GK/MolTac |
blood glucose level |
control IgG monoclonal antibody (1 mg) (for 42 days) |
Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. |
blood glucose amount |
female |
98 days
| 9 |
129.6 |
mg/dl |
5.4 |
16.2 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
110275 |
3168 |
OLETF |
blood glucose level |
control condition (for 84 days) |
Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. |
blood glucose amount |
male |
364 days
| 12 |
186.3 |
mg/dl |
6.84 |
23.69 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
99416 |
2298 |
LH/Mav |
blood glucose level |
streptozotocin (75 mg/kg) then fasting (for 16 hours) then glucose (2 g/kg) (for 1 hours) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood glucose amount |
male |
49 days-56 days |
37 |
300.0 |
mg/dl |
8.0 |
48.66 |
blood glucose analysis |
|
0.0 |
|
0 |
|
|
|
102661 |
2703 |