SS/Jr |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 34 and 38 days) |
Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. |
arterial blood pressure trait |
male |
73 days-80 days |
8 |
|
|
172.0 |
mmHg |
5.0 |
14.14 |
intra-aortic abdominal radiotelemetry |
|
10 |
|
0 |
|
|
average of 24 hr |
|
65496 |
611 |
SS.LEW-(D1Rat211-D1Rat18)/Mco |
heart rate |
controlled sodium content diet (2 %) (between 34 and 38 days) |
Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. |
heart pumping trait |
male |
73 days-80 days |
8 |
|
|
404.0 |
beats/min |
5.0 |
14.14 |
intra-aortic abdominal radiotelemetry |
|
10 |
|
0 |
|
|
diurnal difference |
|
65504 |
611 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
115.5 |
mmHg |
4.2 |
7.27 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65621 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
125.8 |
mmHg |
3.3 |
5.72 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65624 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
99.5 |
mmHg |
1.0 |
1.73 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65643 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
109.3 |
mmHg |
1.9 |
3.29 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65646 |
613 |
WKY/Gcrc |
systolic blood pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
124 days-128 days |
6 |
|
continuous mean |
142.1 |
mmHg |
2.78 |
6.8 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11623 |
109 |
SHRSP/Gcrc |
diastolic blood pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
124 days-128 days |
6 |
|
continuous mean |
140.8 |
mmHg |
2.61 |
6.4 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11625 |
109 |
WKY/Gcrc |
pulse pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
124 days-128 days |
6 |
|
continuous mean |
42.6 |
mmHg |
1.1 |
2.7 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11631 |
109 |
WKY/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
male |
137 days-140 days |
6 |
|
continuous mean |
115.8 |
mmHg |
1.8 |
4.4 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11636 |
109 |
SR/Jr |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to ambient light |
St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 |
arterial blood pressure trait |
female |
56 days-63 days |
8 |
|
serial mean |
83.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
604800.0 |
|
0 |
|
5 s every 5 min daily for a week |
|
|
11702 |
119 |
SHRSP/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
207.9 |
mmHg |
5.5 |
9.53 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65650 |
613 |
WKY/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
105.2 |
mmHg |
2.9 |
5.02 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65672 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
191.2 |
mmHg |
3.4 |
5.89 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65675 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
139.0 |
mmHg |
8.1 |
14.03 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65679 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
123.9 |
mmHg |
3.6 |
6.24 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65684 |
613 |
SS.SR-(D3Arb14-D3Mco36)/Mco |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
67 days-69 days |
6 |
|
|
143.3 |
mmHg |
1.5 |
3.67 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65043 |
283 |
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco |
diastolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
76 days-78 days |
5 |
|
|
110.2 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65062 |
283 |
SS.SR-(D3Arb14-D3Mco36)/Mco |
diastolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
107 days-109 days |
4 |
|
|
157.5 |
mmHg |
3.3 |
6.6 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65064 |
283 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
144.2 |
mmHg |
12.1 |
20.96 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65690 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
134.1 |
mmHg |
4.2 |
7.27 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65696 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
163.0 |
mmHg |
3.8 |
6.58 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65699 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
149.3 |
mmHg |
7.0 |
12.12 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65701 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
133.1 |
mmHg |
4.8 |
8.31 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65707 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
120.6 |
mmHg |
8.5 |
14.72 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65712 |
613 |
SS.MNS-(D2Mit6-D2Rat166)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 21 and 37 days) |
Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28. |
arterial blood pressure trait |
male |
56 days-72 days |
9 |
|
|
148.0 |
mmHg |
4.0 |
12.0 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
none |
|
12324 |
242 |
LEW |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) |
Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. |
arterial blood pressure trait |
male |
66 days-78 days |
6 |
|
serial mean |
95.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1036800 |
|
0 |
|
telemetry probe model PA-D70, Data Sciences, St. Paul, MN |
average of 24 hour averages over 12 days |
|
12736 |
304 |
SS.LEW-(D10Chm10-D10Chm14)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) |
Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. |
arterial blood pressure trait |
male |
66 days-78 days |
5 |
|
serial mean |
168.0 |
mmHg |
6.0 |
13.42 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1036800 |
|
0 |
|
telemetry probe model PA-D70, Data Sciences, St. Paul, MN |
average of 24 hour averages over 12 days |
|
12743 |
304 |
SS.LEW-(D18Chm31-D18Rat55)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8. |
arterial blood pressure trait |
male |
56 days
| 7 |
|
|
131.0 |
mmHg |
4.0 |
10.58 |
intra-aortic abdominal radiotelemetry |
aorta |
|
|
0 |
|
|
|
|
12603 |
269 |
SS.SR-(D13Mit9-D13Mit1)/Jr |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to darkness |
St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 |
arterial blood pressure trait |
female |
56 days-63 days |
8 |
|
serial mean |
89.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
604800.0 |
|
0 |
|
5 s every 5 min nightly for a week |
|
|
11709 |
119 |
SS.SR-(D13Mit9-D13Mit1)/Jr |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to ambient light |
St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 |
arterial blood pressure trait |
female |
56 days-63 days |
8 |
|
serial mean |
82.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
604800.0 |
|
0 |
|
5 s every 5 min daily for a week |
|
|
11710 |
119 |
SS.SHR-(D9Mco72-D9Mco93)/Mco |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 35 and 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
arterial blood pressure trait |
male |
75 days-79 days |
5 |
|
serial mean |
125.0 |
mmHg |
1.28 |
2.86 |
intra-aortic abdominal radiotelemetry |
lower abdominal aorta |
172800 |
|
0 |
|
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 12 4-hour averages over 48 hours using 5 or 6 rats |
|
13038 |
305 |
WKY.SHRSP-(D1Rat200-D1Rat216)(Shbg-Atp1b2)/Bbb |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 12 days) |
Monti J, et al., Hum Mol Genet 2003 Feb 15;12(4):435-9. |
arterial blood pressure trait |
male |
110 days-124 days |
10 |
|
|
136.96 |
mmHg |
1.91 |
6.04 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
|
|
12661 |
281 |
SS/Jr |
heart rate |
controlled sodium content diet (2 %) (for 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
heart pumping trait |
male |
75 days-79 days |
5 |
|
|
378.0 |
beats/min |
9.18 |
20.53 |
intra-aortic abdominal radiotelemetry |
|
172800 |
|
0 |
|
|
|
|
64986 |
305 |
SS.SHR-(D9Mco72-D9Mco93)/Mco |
heart rate |
controlled sodium content diet (2 %) (for 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
heart pumping trait |
male |
75 days-79 days |
5 |
|
|
389.0 |
beats/min |
9.6 |
21.47 |
intra-aortic abdominal radiotelemetry |
|
172800 |
|
0 |
|
|
|
|
64989 |
305 |
SHRSP/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
161.8 |
mmHg |
3.0 |
5.2 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65580 |
613 |
SHRSP/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
113.6 |
mmHg |
2.2 |
3.81 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65584 |
613 |
SHRSP/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
142.1 |
mmHg |
2.3 |
3.98 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65586 |
613 |
WKY/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
4 |
|
continuous mean |
107.7 |
mmHg |
6.9 |
13.8 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65591 |
613 |
WKY/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
123.8 |
mmHg |
3.4 |
5.89 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65600 |
613 |
SHRSP/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
124.0 |
mmHg |
2.5 |
4.33 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65534 |
613 |
LEW/Jr |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 49 days) |
Crespo K, et al., J Hypertens. 2011 Mar;29(3):460-5. |
arterial blood pressure trait |
male |
66 days-73 days |
8 |
|
|
95.0 |
mmHg |
6.0 |
16.97 |
intra-aortic abdominal radiotelemetry |
|
0 |
|
0 |
|
|
|
|
65144 |
563 |
SS/Jr |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 49 days) |
Crespo K, et al., J Hypertens. 2011 Mar;29(3):460-5. |
arterial blood pressure trait |
male |
66 days-73 days |
14 |
|
|
178.0 |
mmHg |
4.0 |
14.97 |
intra-aortic abdominal radiotelemetry |
|
0 |
|
0 |
|
|
|
|
65147 |
563 |
SS.LEW-(D10Rat27-Igfbp4)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14. |
arterial blood pressure trait |
male |
56 days-59 days |
7 |
|
|
150.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
|
86400.0 |
|
0 |
|
|
|
|
67879 |
830 |
SS.LEW-(D10Mco1-D10Mco31)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14. |
arterial blood pressure trait |
male |
56 days-59 days |
7 |
|
|
139.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
|
86400.0 |
|
0 |
|
|
|
|
67882 |
830 |
SS |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
18 |
|
|
173.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70467 |
1438 |
SR/JrHsd |
systolic blood pressure |
controlled sodium content diet (8 %) (between 55 and 56 days) |
Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23. |
arterial blood pressure trait |
male |
139 days-140 days |
5 |
|
|
130.0 |
mmHg |
1.25 |
2.8 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
67854 |
810 |
SR/JrHsd |
systolic blood pressure |
controlled sodium content diet (8 %) (between 83 and 84 days) |
Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23. |
arterial blood pressure trait |
female |
167 days-168 days |
5 |
|
|
120.8 |
mmHg |
3.4 |
7.6 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
67858 |
810 |
SS.LEW-(D17Chm131-D17Chm93)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
129.0 |
mmHg |
8.0 |
17.89 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70443 |
1438 |
SS |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
12 |
|
|
172.0 |
mmHg |
4.0 |
13.86 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70470 |
1438 |
SS.MNS-(D2Wox27-Adh1)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
162.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70478 |
1438 |
SS/Jr |
percent change in heart rate |
sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
10.0 |
% |
0.3 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
|
|
69741 |
344 |
SS.SR-(rs65785750-rs13452155)/Opaz |
pulse pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. |
arterial blood pressure trait |
female |
108 days-112 days |
10 |
|
|
54.11 |
mmHg |
0.4 |
1.26 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70361 |
1358 |
SS.MNS-(D2Rat155-D2Chm419)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
9 |
|
|
124.0 |
mmHg |
6.0 |
18.0 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70457 |
1438 |
LEW/Crlc |
absolute change in heart rate |
sodium ion solution (800 mmol/l) (for 14 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
43 days-50 days |
0 |
|
|
38.0 |
beats/min |
4.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
69695 |
344 |
SS.SR-(D2Rat352-rs63922710)/Opaz |
systolic blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
female |
108 days-112 days |
6 |
|
|
168.4 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70558 |
1458 |
LEW/Crlc |
percent change in heart rate |
sodium ion solution (800 mmol/l) (for 14 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
43 days-50 days |
0 |
|
|
8.0 |
% |
2.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
69699 |
344 |
SS.LEW-(D17Chm14-D17Rat181)/Ayd |
percent change in heart rate |
sodium ion solution (800 mmol/l) (for 14 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
43 days-50 days |
0 |
|
|
10.0 |
% |
2.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
69701 |
344 |
SS.SR-(D2Rat352-rs63922710)/Opaz |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
female |
108 days-112 days |
6 |
|
|
118.5 |
mmHg |
2.2 |
5.39 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70560 |
1458 |
SS.LEW-(D10Rat119-D10Rat133)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
6 |
|
|
183.0 |
mmHg |
9.0 |
22.05 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84479 |
1438 |
SS.LEW-(D10Rat55-D10Rat13)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
164.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84480 |
1438 |
SS.LEW-(D18Wox7-D18Rat67)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
157.0 |
mmHg |
8.0 |
17.89 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84482 |
1438 |
SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (for 77 days) |
Flister MJ, et al., Hypertension. 2012 Oct;60(4):942-8. doi: 10.1161/HYPERTENSIONAHA.112.198200. Epub 2012 Aug 6. |
arterial blood pressure trait |
male |
67 days-77 days |
11 |
|
serial mean |
146.0 |
mmHg |
6.0 |
19.9 |
intra-aortic abdominal radiotelemetry |
|
14400.0 |
|
0 |
|
abdominal aorta |
4 hrs for 3 consecutive days |
|
96868 |
1718 |
SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (0.3 %) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
arterial blood pressure trait |
male |
66 days-73 days |
9 |
|
serial mean |
105.0 |
mmHg |
2.0 |
6.0 |
intra-aortic abdominal radiotelemetry |
|
14400.0 |
|
0 |
|
abdominal aorta |
4 hrs for 3 consecutive days |
|
96871 |
1719 |
SS-Chr 12BN/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (for 77 days) then controlled sodium content diet (8 %) (for 7 days) |
Flister MJ, et al., Hypertension. 2012 Oct;60(4):942-8. doi: 10.1161/HYPERTENSIONAHA.112.198200. Epub 2012 Aug 6. |
arterial blood pressure trait |
male |
74 days-84 days |
10 |
|
serial mean |
144.0 |
mmHg |
6.0 |
18.97 |
intra-aortic abdominal radiotelemetry |
|
14400.0 |
|
0 |
|
abdominal aorta |
4 hrs for 3 consecutive days |
|
96863 |
1718 |
SS-Chr 12BN.SS-(D12Arb13-D12Mit2)/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (for 77 days) |
Flister MJ, et al., Hypertension. 2012 Oct;60(4):942-8. doi: 10.1161/HYPERTENSIONAHA.112.198200. Epub 2012 Aug 6. |
arterial blood pressure trait |
male |
67 days-77 days |
8 |
|
serial mean |
114.0 |
mmHg |
2.0 |
5.66 |
intra-aortic abdominal radiotelemetry |
|
14400.0 |
|
0 |
|
abdominal aorta |
4 hrs for 3 consecutive days |
|
96864 |
1718 |
SS.LEW-(D3Rat52-D3Chm63)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
7 |
|
|
146.0 |
mmHg |
6.0 |
15.87 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84477 |
1438 |
SS.LEW-(D10Rat194-D10Chm243)(D16Chm48-D16Chm60)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
150.0 |
mmHg |
9.0 |
25.46 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84487 |
1438 |
SS.LEW-(D10Chm10-D10Rat11)(D16Chm48-D16Chm60)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
137.0 |
mmHg |
3.0 |
8.49 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84488 |
1438 |
SS.LEW-(D17Chm131-D17Chm93)(D17Rat84-D17Chm17)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
7 |
|
|
144.0 |
mmHg |
6.0 |
15.87 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84495 |
1438 |
LEW/Crl |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 41 days) |
Crespo K, et al., Circ Cardiovasc Genet. 2015 Aug;8(4):610-7. doi: 10.1161/CIRCGENETICS.114.000965. Epub 2015 May 11. |
arterial blood pressure trait |
male |
67 days-77 days |
14 |
|
|
96.0 |
mmHg |
2.0 |
7.48 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
864000.0 |
|
0 |
|
|
|
|
97140 |
1878 |
LEW.SS-(D7Rat27-D7Mgh1)(D17Rat15-D17Rat51)(D10Mgh6-D10Mgh1)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 41 days) |
Crespo K, et al., Circ Cardiovasc Genet. 2015 Aug;8(4):610-7. doi: 10.1161/CIRCGENETICS.114.000965. Epub 2015 May 11. |
arterial blood pressure trait |
male |
67 days-77 days |
5 |
|
|
105.0 |
mmHg |
3.0 |
6.71 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
864000.0 |
|
0 |
|
|
|
|
97145 |
1878 |
LEW.SS-((D10Mgh6-D10Mgh1)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 41 days) |
Crespo K, et al., Circ Cardiovasc Genet. 2015 Aug;8(4):610-7. doi: 10.1161/CIRCGENETICS.114.000965. Epub 2015 May 11. |
arterial blood pressure trait |
male |
67 days-77 days |
6 |
|
|
109.0 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
864000.0 |
|
0 |
|
|
|
|
97146 |
1878 |
SS-Agtrapem4Mcwi-/- |
systolic blood pressure |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
139.0 |
mmHg |
2.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98416 |
2059 |
SS/Hsd |
heart rate |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
heart pumping trait |
male |
58 days-67 days |
0 |
|
serial mean |
339.0 |
beats/min |
4.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98424 |
2059 |
GK |
diastolic blood pressure |
vehicle control condition (for 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168 days
| 6 |
|
|
98.0 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 4 weeks |
daytime measurement |
|
103544 |
2827 |
GK |
diastolic blood pressure |
control condition and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133 days-140 days |
5 |
|
|
104.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/night for 1 week |
nighttime measurement |
|
103549 |
2827 |
GK |
diastolic blood pressure |
vehicle control condition (for 28 days) and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168 days
| 6 |
|
|
104.0 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/night for 4 weeks |
nighttime measurement |
|
103552 |
2827 |
GK |
heart rate |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
heart pumping trait |
male |
130 days-140 days |
6 |
|
|
272.0 |
beats/min |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/day for 1 week |
daytime measurement |
|
103556 |
2827 |
GK |
heart rate |
salidroside (40 mg/kg) (for 28 days) and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
heart pumping trait |
male |
168 days
| 5 |
|
|
339.0 |
beats/min |
14.0 |
31.3 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/night for 4 weeks |
nighttime measurement |
|
103569 |
2827 |
WKY/NCrl |
number of spontaneous locomotor movements per unit time |
vehicle control condition (between 1 and 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
voluntary movement trait |
male |
168 days
| 6 |
|
|
0.9 |
/min |
0.1 |
0.24 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 4 weeks |
number of spontaneous locomotor movements per unit time (CMO:0003644) |
|
103574 |
2827 |
GK |
number of spontaneous locomotor movements per unit time |
control condition and dark phase of controlled light/dark cycle (for 3 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
voluntary movement trait |
male |
140 days
| 5 |
|
|
4.2 |
/min |
0.5 |
1.12 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/night |
number of spontaneous locomotor movements per unit time (CMO:0003644) |
|
103581 |
2827 |
WKY/NCrl |
number of spontaneous locomotor movements per unit time |
salidroside (40 mg/kg) (between 1 and 28 days) and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
voluntary movement trait |
male |
168 days
| 6 |
|
|
3.4 |
/min |
0.3 |
0.73 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/night for 4 weeks |
number of spontaneous locomotor movements per unit time (CMO:0003644) |
|
103583 |
2827 |
GK |
number of spontaneous locomotor movements per unit time |
salidroside (40 mg/kg) (between 1 and 28 days) and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
voluntary movement trait |
male |
168 days
| 5 |
|
|
3.5 |
/min |
0.4 |
0.89 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/night for 4 weeks |
number of spontaneous locomotor movements per unit time (CMO:0003644) |
|
103585 |
2827 |
GK |
systolic blood pressure |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133 days-140 days |
6 |
|
|
135.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 1 week |
daytime measurement |
|
103524 |
2827 |
GK |
systolic blood pressure |
salidroside (40 mg/kg) (for 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168 days
| 5 |
|
|
139.0 |
mmHg |
3.0 |
6.71 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 4 weeks |
daytime measurement |
|
103529 |
2827 |
SS-Nppaem4Mcwi-/- |
mean arterial blood pressure |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
163.0 |
mmHg |
6.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98399 |
2059 |
SS-Mthfrem1Mcwi-/+ |
diastolic blood pressure |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
110.0 |
mmHg |
4.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98408 |
2059 |
SS-Renem1Mcwi+/+ |
mean arterial blood pressure |
controlled sodium content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
arterial blood pressure trait |
male |
66 days-69 days |
5 |
|
serial mean |
125.46 |
mmHg |
2.07 |
4.63 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98374 |
2038 |
SS-Renem1Mcwi+/+ |
diastolic blood pressure |
controlled sodium chloride content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
arterial blood pressure trait |
male |
66 days-69 days |
5 |
|
serial mean |
101.76 |
mmHg |
2.81 |
6.28 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98375 |
2038 |
SS-Renem1Mcwi+/- |
diastolic blood pressure |
controlled sodium content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
arterial blood pressure trait |
female |
66 days-69 days |
8 |
|
serial mean |
94.19 |
mmHg |
1.82 |
5.15 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98387 |
2038 |
SS-Renem1Mcwi-/- |
heart rate |
controlled sodium chloride content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
heart pumping trait |
male |
66 days-69 days |
8 |
|
serial mean |
402.94 |
beats/min |
4.46 |
12.61 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98393 |
2038 |
Crl:WI |
mean arterial blood pressure |
control condition |
Stepp DW, et al., Physiol Rep. 2013 Nov;1(6):e00146. doi: 10.1002/phy2.146. Epub 2013 Nov 13. |
arterial blood pressure trait |
male |
70 days-126 days |
8 |
every 10 min for 24hr |
|
108.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
105536 |
3017 |
Crl:WI |
mean arterial blood pressure |
control condition |
Stepp DW, et al., Physiol Rep. 2013 Nov;1(6):e00146. doi: 10.1002/phy2.146. Epub 2013 Nov 13. |
arterial blood pressure trait |
male |
70 days-126 days |
8 |
night every 10 min |
|
111.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
105544 |
3017 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
115.0 |
mmHg |
2.6 |
4.5 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65612 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
156.3 |
mmHg |
4.9 |
8.49 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65615 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
145.7 |
mmHg |
6.1 |
10.57 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65623 |
613 |
SS/Jr |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
76 days-78 days |
5 |
|
|
217.9 |
mmHg |
2.1 |
4.7 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65044 |
283 |
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
76 days-78 days |
5 |
|
|
157.7 |
mmHg |
2.3 |
5.14 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65046 |
283 |
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
107 days-109 days |
4 |
|
|
196.6 |
mmHg |
3.6 |
7.2 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65049 |
283 |
SS/Jr |
diastolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
107 days-109 days |
3 |
|
|
164.9 |
mmHg |
2.3 |
3.98 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65063 |
283 |
SS/Jr |
diastolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
114 days-116 days |
3 |
|
|
158.2 |
mmHg |
3.9 |
6.75 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65066 |
283 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
118.2 |
mmHg |
5.6 |
9.7 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65703 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
126.6 |
mmHg |
4.8 |
8.31 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65706 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
156.0 |
mmHg |
2.5 |
4.33 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65711 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
95.6 |
mmHg |
7.1 |
12.3 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65720 |
613 |
SHRSP/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
166.5 |
mmHg |
3.8 |
6.58 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65582 |
613 |
LEW.SS-(D18Chm31-D18Mit8)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8. |
arterial blood pressure trait |
male |
56 days
| 7 |
|
|
92.0 |
mmHg |
2.0 |
5.29 |
intra-aortic abdominal radiotelemetry |
aorta |
|
|
0 |
|
|
|
|
12615 |
269 |
LEW.SS-(D2Uia5-D2Rat143)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8. |
arterial blood pressure trait |
male |
56 days
| 5 |
|
|
91.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
aorta |
|
|
0 |
|
|
|
|
12587 |
269 |
SS/Jr |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 35 and 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
arterial blood pressure trait |
male |
75 days-79 days |
5 |
|
serial mean |
158.0 |
mmHg |
1.76 |
3.94 |
intra-aortic abdominal radiotelemetry |
lower abdominal aorta |
172800 |
|
0 |
|
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 12 4-hour averages over 48 hours using 5 or 6 rats |
|
13035 |
305 |
SS.LEW-(D10Chm10-D10Rat11)/Ayd |
absolute change in heart rate |
sodium ion solution (800 mmol/l) (for 14 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
43 days-50 days |
0 |
|
|
59.0 |
beats/min |
4.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
69696 |
344 |
SS/Jr |
absolute change in heart rate |
sodium ion solution (800 mmol/l) (for 14 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
43 days-50 days |
0 |
|
|
54.0 |
beats/min |
6.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
69698 |
344 |
SS.LEW-(D18Chm90-D18Chm4)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
170.0 |
mmHg |
8.0 |
17.89 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84481 |
1438 |
SS-Chr 12BN.SS-(D12Arb13-D12Mit2)/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (for 77 days) then controlled sodium content diet (8 %) (for 7 days) |
Flister MJ, et al., Hypertension. 2012 Oct;60(4):942-8. doi: 10.1161/HYPERTENSIONAHA.112.198200. Epub 2012 Aug 6. |
arterial blood pressure trait |
male |
74 days-84 days |
8 |
|
serial mean |
136.0 |
mmHg |
5.0 |
14.14 |
intra-aortic abdominal radiotelemetry |
|
14400.0 |
|
0 |
|
abdominal aorta |
4 hrs for 3 consecutive days |
|
96865 |
1718 |
LEW/Crlc |
absolute change in mean arterial blood pressure |
sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
arterial blood pressure trait |
male |
53 days-61 days |
0 |
|
|
13.0 |
mmHg |
1.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
|
|
69726 |
344 |
SS.LEW-(D17Chm14-D17Rat181)/Ayd |
percent change in mean arterial blood pressure |
sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
arterial blood pressure trait |
male |
53 days-61 days |
0 |
|
|
15.0 |
% |
0.2 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
% change map |
|
69732 |
344 |
LEW/Crlc |
absolute change in heart rate |
sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
29.0 |
beats/min |
2.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
|
|
69734 |
344 |
LEW/Crlc |
maximum change in heart rate to change in mean arterial blood pressure ratio |
sodium ion solution (800 mmol/l) (for 4 days) then phenylephrine (5-50 ug/min) then sodium nitroprusside (10-100 ug/min) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
-2.9 |
beats/min/mmHg |
0.2 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
Maximum slope, bpm/mm Hg |
|
69742 |
344 |
SS.LEW-(D10Rat194-D10Chm243)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
148.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70491 |
1438 |
SS.LEW-(D3Chm64-D3Rat17)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
195.0 |
mmHg |
9.0 |
25.46 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84478 |
1438 |
SS.LEW-(D8Rat58-D8Chm12)(D10Chm10-D10Rat11)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
150.0 |
mmHg |
4.0 |
11.31 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84489 |
1438 |
SS.LEW-(D2Uia5-D2Mit6)(D10Rat194-D10Chm243)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
6 |
|
|
183.0 |
mmHg |
9.0 |
22.05 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84497 |
1438 |
SS.MNS-(D2Chm33-Tm2sf1),LEW-(D10Rat194-D10Chm243)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
7 |
|
|
131.0 |
mmHg |
3.0 |
7.94 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84510 |
1438 |
SS.BN-(D12Hmgc7-D12Hmgc6)/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (between 42 and 49 days) |
Prisco SZ, et al., Hypertension. 2014 Jul 7. pii: HYPERTENSIONAHA.114.03550. |
arterial blood pressure trait |
male |
71 days-77 days |
6 |
|
|
110.0 |
mmHg |
1.0 |
2.45 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
96806 |
1698 |
SS.BN-(D12Hmgc3- D12Got29)/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (between 42 and 49 days) then controlled sodium content diet (8 %) (for 21 days) |
Prisco SZ, et al., Hypertension. 2014 Jul 7. pii: HYPERTENSIONAHA.114.03550. |
arterial blood pressure trait |
male |
92 days-98 days |
5 |
|
|
141.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
96809 |
1698 |
LEW/Crl |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 46 days) |
Crespo K, et al., Circ Cardiovasc Genet. 2015 Aug;8(4):610-7. doi: 10.1161/CIRCGENETICS.114.000965. Epub 2015 May 11. |
arterial blood pressure trait |
male |
67 days-82 days |
9 |
|
|
98.0 |
mmHg |
2.0 |
6.0 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1296000.0 |
|
0 |
|
|
|
|
97142 |
1878 |
SS-Mthfrem1Mcwi-/+ |
mean arterial blood pressure |
controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
130.0 |
mmHg |
4.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98401 |
2059 |
SS-Nppbem2Mcwi-/- |
diastolic blood pressure |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
111.0 |
mmHg |
3.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98405 |
2059 |
SS/Jr |
pulse pressure |
controlled sodium content diet (2 %) (between 34 and 38 days) |
Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. |
arterial blood pressure trait |
male |
73 days-80 days |
8 |
|
|
52.0 |
mmHg |
3.4 |
9.62 |
intra-aortic abdominal radiotelemetry |
|
10 |
|
0 |
|
|
average of 24 hr |
|
65495 |
611 |
SS.LEW-(D1Rat211-D1Rat18)/Mco |
systolic blood pressure |
controlled sodium content diet (2 %) (between 34 and 38 days) |
Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. |
arterial blood pressure trait |
male |
73 days-80 days |
8 |
|
|
171.0 |
mmHg |
3.4 |
9.62 |
intra-aortic abdominal radiotelemetry |
|
10 |
|
0 |
|
|
average of 24 hr |
|
65498 |
611 |
SS.LEW-(D1Rat211-D1Rat18)/Mco |
diastolic blood pressure |
controlled sodium content diet (2 %) (between 34 and 38 days) |
Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. |
arterial blood pressure trait |
male |
73 days-80 days |
8 |
|
|
123.0 |
mmHg |
2.9 |
8.2 |
intra-aortic abdominal radiotelemetry |
|
10 |
|
0 |
|
|
average of 24 hr |
|
65499 |
611 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
117.8 |
mmHg |
3.3 |
5.72 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65613 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
178.0 |
mmHg |
5.0 |
8.66 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65614 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
122.8 |
mmHg |
4.5 |
7.79 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65618 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
151.3 |
mmHg |
3.5 |
6.06 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65628 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
138.1 |
mmHg |
4.8 |
8.31 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65629 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
108.9 |
mmHg |
3.7 |
6.41 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65631 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
116.3 |
mmHg |
6.4 |
11.09 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65639 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
113.5 |
mmHg |
1.3 |
2.25 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65647 |
613 |
WKY/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
137 days-140 days |
6 |
|
continuous mean |
147.1 |
mmHg |
3.76 |
9.2 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11634 |
109 |
SHRSP/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
137 days-140 days |
6 |
|
continuous mean |
150.5 |
mmHg |
4.45 |
10.9 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11635 |
109 |
WKY/Gcrc |
pulse pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
137 days-140 days |
6 |
|
continuous mean |
45.9 |
mmHg |
1.14 |
2.8 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11640 |
109 |
SR/Jr |
systolic blood pressure |
controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to darkness |
St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 |
arterial blood pressure trait |
female |
56 days-63 days |
8 |
|
serial mean |
128.0 |
mmHg |
2.0 |
5.66 |
intra-aortic abdominal radiotelemetry |
|
604800.0 |
|
0 |
|
5 s every 5 min nightly for a week |
|
|
11699 |
119 |
SS.SR-(D13Mit9-D13Mit1)/Jr |
systolic blood pressure |
controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to darkness |
St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 |
arterial blood pressure trait |
female |
56 days-63 days |
8 |
|
serial mean |
122.0 |
mmHg |
2.0 |
5.66 |
intra-aortic abdominal radiotelemetry |
|
604800.0 |
|
0 |
|
5 s every 5 min nightly for a week |
|
|
11707 |
119 |
WKY.SHRSP-(D1Rat200-D1Rat216)/Bbb |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 12 days) |
Monti J, et al., Hum Mol Genet 2003 Feb 15;12(4):435-9. |
arterial blood pressure trait |
male |
110 days-124 days |
12 |
|
|
128.65 |
mmHg |
1.22 |
4.23 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
|
|
12657 |
281 |
WKY.SHRSP-(Shbg-Atp1b2)/Bbb |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 12 days) |
Monti J, et al., Hum Mol Genet 2003 Feb 15;12(4):435-9. |
arterial blood pressure trait |
male |
110 days-124 days |
33 |
|
|
129.42 |
mmHg |
0.85 |
4.88 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
|
|
12659 |
281 |
SHRSP/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
185.5 |
mmHg |
4.5 |
7.79 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65653 |
613 |
SHRSP/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
167.2 |
mmHg |
5.2 |
9.01 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65655 |
613 |
SHRSP/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
171.2 |
mmHg |
5.3 |
9.18 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65658 |
613 |
WKY/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
4 |
|
continuous mean |
96.8 |
mmHg |
6.4 |
12.8 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65666 |
613 |
WKY/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
4 |
|
continuous mean |
104.4 |
mmHg |
6.9 |
13.8 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65667 |
613 |
WKY/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
98.8 |
mmHg |
2.8 |
4.85 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65669 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
178.3 |
mmHg |
13.0 |
22.52 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65695 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
97.8 |
mmHg |
6.8 |
11.78 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65704 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
120.0 |
mmHg |
6.6 |
11.43 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65709 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
104.8 |
mmHg |
7.5 |
12.99 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65721 |
613 |
SS/Jr |
diastolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
67 days-69 days |
5 |
|
|
125.2 |
mmHg |
3.0 |
6.71 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65057 |
283 |
SS.SR-(D3Arb14-D3Mco36)/Mco |
diastolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
114 days-116 days |
4 |
|
|
165.3 |
mmHg |
4.6 |
9.2 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65067 |
283 |
SS.SR-(D3Arb14-D3Mco36)/Mco |
diastolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
147 days-149 days |
2 |
|
|
162.3 |
mmHg |
2.2 |
3.11 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65070 |
283 |
WKY/Gcrc |
pulse pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
male |
124 days-128 days |
6 |
|
continuous mean |
50.0 |
mmHg |
1.76 |
4.3 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11630 |
109 |
SS.LEW-(D10Chm224-D10Chm6)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) |
Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. |
arterial blood pressure trait |
male |
66 days-78 days |
9 |
|
serial mean |
138.0 |
mmHg |
6.0 |
18.0 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1036800 |
|
0 |
|
telemetry probe model PA-D70, Data Sciences, St. Paul, MN |
average of 24 hour averages over 12 days |
|
12748 |
304 |
SS.SHR-(D9Mco72-D9Mco93)/Mco |
diastolic blood pressure |
controlled sodium content diet (2 %) (between 35 and 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
arterial blood pressure trait |
male |
75 days-79 days |
5 |
|
serial mean |
103.0 |
mmHg |
1.14 |
2.55 |
intra-aortic abdominal radiotelemetry |
lower abdominal aorta |
172800 |
|
0 |
|
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 12 4-hour averages over 48 hours using 5 or 6 rats |
|
13034 |
305 |
SS.SHR-(D9Wox16-D9Rat64)/Mco |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 35 and 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
arterial blood pressure trait |
male |
75 days-79 days |
5 |
|
serial mean |
125.0 |
mmHg |
1.35 |
3.02 |
intra-aortic abdominal radiotelemetry |
lower abdominal aorta |
172800 |
|
0 |
|
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 12 4-hour averages over 48 hours using 5 or 6 rats |
|
13036 |
305 |
SS.LEW-(D17Rat65-Prl)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 43 and 47 days) |
Grondin M, et al., Physiol Genomics 2005 Mar 21;21(1):112-6. Epub 2005 Jan 4. |
arterial blood pressure trait |
male |
88 days-92 days |
5 |
|
|
139.0 |
mmHg |
5.0 |
11.18 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
measure every 2 min for 24 hrs |
|
12466 |
261 |
SS.LEW-(D17Chm9-D17Rat97)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 43 and 47 days) |
Grondin M, et al., Physiol Genomics 2005 Mar 21;21(1):112-6. Epub 2005 Jan 4. |
arterial blood pressure trait |
male |
88 days-92 days |
10 |
|
|
170.0 |
mmHg |
7.0 |
22.14 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
measure every 2 min for 24 hrs |
|
12474 |
261 |
SS/Jr |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 21 and 37 days) |
Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28. |
arterial blood pressure trait |
male |
56 days-72 days |
18 |
|
|
170.0 |
mmHg |
4.0 |
16.97 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
|
|
12354 |
242 |
SS.MNS-(D2Chm51-D2Rat341)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 21 and 37 days) |
Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28. |
arterial blood pressure trait |
male |
56 days-72 days |
8 |
|
|
144.0 |
mmHg |
2.0 |
5.66 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
|
|
12356 |
242 |
SS.MNS-(D2Wox27-Adh1)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 21 and 37 days) |
Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28. |
arterial blood pressure trait |
male |
56 days-72 days |
5 |
|
|
162.0 |
mmHg |
7.0 |
15.65 |
intra-aortic abdominal radiotelemetry |
|
0 |
|
0 |
|
|
|
|
12361 |
242 |
SS/Jr |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 43 and 47 days) |
Grondin M, et al., Physiol Genomics 2005 Mar 21;21(1):112-6. Epub 2005 Jan 4. |
arterial blood pressure trait |
male |
88 days-92 days |
19 |
|
|
169.0 |
mmHg |
4.0 |
17.44 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
measure every 2 min for 24 hrs |
|
12422 |
261 |
SS/Jr |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8. |
arterial blood pressure trait |
male |
56 days
| 10 |
|
|
175.0 |
mmHg |
4.0 |
12.65 |
intra-aortic abdominal radiotelemetry |
aorta |
|
|
0 |
|
|
|
|
12544 |
269 |
SS.LEW-(D2Rat199-D2Mco17)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8. |
arterial blood pressure trait |
male |
56 days
| 8 |
|
|
205.0 |
mmHg |
3.0 |
8.49 |
intra-aortic abdominal radiotelemetry |
aorta |
|
|
0 |
|
|
|
|
12586 |
269 |
SS.LEW-(D10Mco30-D10Got107)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) |
Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. |
arterial blood pressure trait |
male |
66 days-78 days |
5 |
|
serial mean |
168.0 |
mmHg |
6.0 |
13.42 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1036800 |
|
0 |
|
telemetry probe model PA-D70, Data Sciences, St. Paul, MN |
average of 24 hour averages over 12 days |
|
12738 |
304 |
SS.LEW-(D10Chm155-D10Rat127)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) |
Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. |
arterial blood pressure trait |
male |
66 days-78 days |
8 |
|
serial mean |
148.0 |
mmHg |
6.0 |
16.97 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1036800 |
|
0 |
|
telemetry probe model PA-D70, Data Sciences, St. Paul, MN |
average of 24 hour averages over 12 days |
|
12740 |
304 |
SS/Jr |
systolic blood pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 42 days) |
Saad Y, et al., Hypertension. 2007 |
arterial blood pressure trait |
male |
81 days-84 days |
9 |
|
|
213.0 |
mmHg |
7.47 |
22.41 |
intra-aortic abdominal radiotelemetry |
aorta |
345600.0 |
|
0 |
|
|
recorded every 5 minutes for 4 days |
|
12072 |
205 |
SS.SHR-(D9Mco74-D9Rat64)/Mco |
heart rate |
controlled sodium content diet (2 %) (for 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
heart pumping trait |
male |
75 days-79 days |
5 |
|
|
398.0 |
beats/min |
9.49 |
21.22 |
intra-aortic abdominal radiotelemetry |
|
172800 |
|
0 |
|
|
|
|
64988 |
305 |
SHRSP/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
185.1 |
mmHg |
1.1 |
1.91 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65581 |
613 |
LEW.SS-(D7Rat73-D7Rat128)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 49 days) |
Crespo K, et al., J Hypertens. 2011 Mar;29(3):460-5. |
arterial blood pressure trait |
male |
66 days-73 days |
6 |
|
|
93.0 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
|
0 |
|
0 |
|
|
|
|
65149 |
563 |
SS/JrHsd |
systolic blood pressure |
controlled sodium content diet (8 %) (between 55 and 56 days) |
Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23. |
arterial blood pressure trait |
male |
139 days-140 days |
6 |
|
|
220.0 |
mmHg |
7.1 |
17.4 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
67851 |
810 |
SS.LEW-(Prlr-D2Rat143)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
184.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70474 |
1438 |
SS/JrHsd |
pulse pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
male |
108 days-112 days |
8 |
|
|
57.1 |
mmHg |
0.4 |
1.13 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70504 |
1458 |
SS/Jr |
absolute change in heart rate |
sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
45.0 |
beats/min |
3.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
|
|
69737 |
344 |
SS.LEW-(D10Chm246-D10Chm257)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
10 |
|
|
151.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70490 |
1438 |
SS.SR-(rs65785750-rs13452155)/Opaz |
systolic blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. |
arterial blood pressure trait |
female |
108 days-112 days |
10 |
|
|
185.9 |
mmHg |
3.8 |
12.02 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70352 |
1358 |
SS/JrHsd |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 55 and 56 days) |
Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23. |
arterial blood pressure trait |
male |
139 days-140 days |
6 |
|
|
162.7 |
mmHg |
7.88 |
19.3 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
67869 |
810 |
SR/JrHsd |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 55 and 56 days) |
Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23. |
arterial blood pressure trait |
male |
139 days-140 days |
5 |
|
|
93.4 |
mmHg |
1.61 |
3.6 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
67870 |
810 |
SS.SR-(rs106870553-rs63922710)/Opaz |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
female |
108 days-112 days |
10 |
|
|
135.2 |
mmHg |
2.8 |
8.85 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70568 |
1458 |
SS.MNS-(D2Rat155-D2Chm161)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 35 and 105 days) |
Crespo K, et al., J Hypertens. 2013 May;31(5):927-35. doi: 10.1097/HJH.0b013e32835edc7e. |
arterial blood pressure trait |
male |
66 days-86 days |
9 |
|
serial mean |
125.0 |
mmHg |
2.0 |
6.0 |
intra-aortic abdominal radiotelemetry |
|
2.0 |
|
0 |
|
|
for 2 wks |
has records that will be duplicated if entered need to add multiple refs once the functionality is in |
96581 |
1665 |
SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (between 42 and 49 days) then controlled sodium content diet (8 %) (for 21 days) |
Prisco SZ, et al., Hypertension. 2014 Jul 7. pii: HYPERTENSIONAHA.114.03550. |
arterial blood pressure trait |
male |
92 days-98 days |
14 |
|
|
160.0 |
mmHg |
3.0 |
11.22 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
96800 |
1698 |
SS.LEW-(D8Rat58-D8Chm12)(D10Rat194-D10Chm243)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
161.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84490 |
1438 |
SS.LEW-(D8Chm12-D8Rat15)(D10Rat194-D10Chm243)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
134.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84491 |
1438 |
SS.LEW-(D16Chm48-D16Chm60)(D18Rat101-D18Rat92)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
141.0 |
mmHg |
4.0 |
8.94 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84498 |
1438 |
SS.LEW-(D1Rat320-D1Mgh32)(D10Rat194-D10Chm243)(D10Chm10-D10Rat11)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
6 |
|
|
109.0 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84501 |
1438 |
SS.LEW-(D7Uia3-D7Mgh1)(D10Rat194-D10Chm243)(D10Chm10-D10Rat11)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
125.0 |
mmHg |
3.0 |
6.71 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84503 |
1438 |
SS.MNS-(D2Chm33-Tm2sf1),LEW-(D10Chm10-D10Rat11)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
133.0 |
mmHg |
8.0 |
17.89 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84509 |
1438 |
ACI.FHH-(D1Mit18-D1Rat90)(D14Mit11-D14Rat33)(D14Rat65-D14Rat90)/Eur |
mean arterial blood pressure |
right nephrectomy (for 35 days) then controlled sodium content diet (0.4 %) (for 35 days) |
O'Meara CC, et al., J Am Soc Nephrol. 2011 Mar;22(3):518-25. Epub 2010 Dec 2. |
arterial blood pressure trait |
male |
70 days-77 days |
6 |
|
serial mean |
111.08 |
mmHg |
2.04 |
5.0 |
intra-aortic abdominal radiotelemetry |
|
259200.0 |
right nephrectomy |
35 |
days |
10 s every 2 m for 3 h |
|
|
84745 |
1600 |
LEW.SS-(D17Rat15-D17Rat51)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 41 days) |
Crespo K, et al., Circ Cardiovasc Genet. 2015 Aug;8(4):610-7. doi: 10.1161/CIRCGENETICS.114.000965. Epub 2015 May 11. |
arterial blood pressure trait |
male |
67 days-77 days |
5 |
|
|
89.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
864000.0 |
|
0 |
|
|
|
|
97143 |
1878 |
SS-Nppaem4Mcwi-/- |
systolic blood pressure |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
195.0 |
mmHg |
5.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98413 |
2059 |
WKY/NCrl |
number of spontaneous locomotor movements per unit time |
control condition and dark phase of controlled light/dark cycle (for 3 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
voluntary movement trait |
male |
140 days
| 6 |
|
|
3.8 |
/min |
0.3 |
0.73 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/night |
number of spontaneous locomotor movements per unit time (CMO:0003644) |
|
103579 |
2827 |
GK |
number of spontaneous locomotor movements per unit time |
vehicle control condition (between 1 and 28 days) and dark phase of controlled light/dark cycle |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
voluntary movement trait |
male |
168 days
| 6 |
|
|
2.9 |
/min |
0.1 |
0.24 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/night for 4 weeks |
number of spontaneous locomotor movements per unit time (CMO:0003644) |
|
103584 |
2827 |
WKY/NCrl |
heart rate |
control condition and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
heart pumping trait |
male |
133 days-140 days |
6 |
|
|
347.0 |
beats/min |
6.0 |
14.7 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/night for 1 week |
nighttime measurement |
|
103562 |
2827 |
WKY/NCrl |
number of spontaneous locomotor movements per unit time |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
voluntary movement trait |
male |
140 days
| 6 |
|
|
1.0 |
/min |
0.1 |
0.24 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
number of spontaneous locomotor movements per unit time (CMO:0003644) |
|
103571 |
2827 |
SS-Agtrapem4Mcwi-/- |
diastolic blood pressure |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
120.0 |
mmHg |
5.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98409 |
2059 |
SS-Renem1Mcwi-/- |
mean arterial blood pressure |
controlled sodium chloride content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
arterial blood pressure trait |
male |
66 days-69 days |
8 |
|
serial mean |
58.36 |
mmHg |
2.38 |
6.73 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98380 |
2038 |
SS-Renem1Mcwi+/- |
systolic blood pressure |
controlled sodium content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
arterial blood pressure trait |
female |
66 days-69 days |
8 |
|
serial mean |
139.28 |
mmHg |
2.25 |
6.36 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98385 |
2038 |
SS-Plod1em1Mcwi-/- |
mean arterial blood pressure |
controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
143.0 |
mmHg |
3.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98397 |
2059 |
SS-Nppaem4Mcwi-/- |
diastolic blood pressure |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
143.0 |
mmHg |
5.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98406 |
2059 |
Crl:WI |
heart rate |
control condition |
Stepp DW, et al., Physiol Rep. 2013 Nov;1(6):e00146. doi: 10.1002/phy2.146. Epub 2013 Nov 13. |
heart pumping trait |
male |
70 days-126 days |
8 |
|
|
354.0 |
beats/min |
4.0 |
11.31 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
105546 |
3017 |
WI-Mc4rm1Hubr |
heart rate |
control condition |
Stepp DW, et al., Physiol Rep. 2013 Nov;1(6):e00146. doi: 10.1002/phy2.146. Epub 2013 Nov 13. |
heart pumping trait |
male |
70 days-126 days |
8 |
|
|
340.0 |
beats/min |
6.0 |
16.97 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
105547 |
3017 |
WI-Mc4rm1Hubr |
mean arterial blood pressure |
control condition |
Stepp DW, et al., Physiol Rep. 2013 Nov;1(6):e00146. doi: 10.1002/phy2.146. Epub 2013 Nov 13. |
arterial blood pressure trait |
male |
70 days-126 days |
8 |
day every 10 min |
|
107.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
105543 |
3017 |
WKY/Gcrc |
diastolic blood pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
male |
124 days-128 days |
6 |
|
continuous mean |
110.4 |
mmHg |
2.57 |
6.3 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11626 |
109 |
SS.LEW-(D10Mco84-D10Mco134)/Mco |
systolic blood pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 42 days) |
Saad Y, et al., Hypertension. 2007 |
arterial blood pressure trait |
male |
81 days-84 days |
8 |
|
|
188.0 |
mmHg |
4.27 |
12.08 |
intra-aortic abdominal radiotelemetry |
aorta |
345600.0 |
|
0 |
|
|
recorded every 5 minutes for 4 days |
|
12075 |
205 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
110.5 |
mmHg |
3.1 |
5.37 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65620 |
613 |
SHRSP/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
156.4 |
mmHg |
6.5 |
11.26 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65683 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
130.8 |
mmHg |
4.8 |
8.31 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65685 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
163.5 |
mmHg |
12.2 |
21.13 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65694 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
144.2 |
mmHg |
4.5 |
7.79 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65697 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
112.1 |
mmHg |
7.2 |
12.47 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65708 |
613 |
SHRSP/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
152.9 |
mmHg |
5.2 |
9.01 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65654 |
613 |
SHRSP/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
139.0 |
mmHg |
3.4 |
5.89 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65660 |
613 |
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco |
diastolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
67 days-69 days |
5 |
|
|
95.1 |
mmHg |
1.6 |
3.58 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65058 |
283 |
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco |
diastolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
147 days-149 days |
2 |
|
|
172.9 |
mmHg |
3.5 |
4.95 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65071 |
283 |
SHRSP/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
148.4 |
mmHg |
1.0 |
1.73 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65587 |
613 |
SS.SR-(D13Mit9-D13Mit1)/Jr |
systolic blood pressure |
controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to darkness |
St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 |
arterial blood pressure trait |
male |
70 days-77 days |
8 |
|
serial mean |
136.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
604800.0 |
|
0 |
|
5 s every 5 min nightly for a week |
|
|
11703 |
119 |
SS |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
21 |
|
|
177.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70468 |
1438 |
SS.LEW-(D17Chm85-D17Chm71)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
10 |
|
|
168.0 |
mmHg |
5.0 |
15.81 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70494 |
1438 |
SS.MNS-(D2Chm366-D2Rat52)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
9 |
|
|
139.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70485 |
1438 |
SS/Jr |
percent change in heart rate |
sodium ion solution (800 mmol/l) (for 14 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
43 days-50 days |
0 |
|
|
10.0 |
% |
1.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
69702 |
344 |
SS.LEW-(D10Chm224-D10Chm6)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14. |
arterial blood pressure trait |
male |
56 days-59 days |
11 |
|
|
144.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
|
86400.0 |
|
0 |
|
|
|
|
67885 |
830 |
SS.LEW-(D18Chm59-D18Rat1)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
142.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84484 |
1438 |
SS.LEW-(D17Chm14-D17Rat65)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
173.0 |
mmHg |
8.0 |
17.89 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70493 |
1438 |
SS |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
15 |
|
|
172.0 |
mmHg |
4.0 |
15.49 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70465 |
1438 |
SS-Chr 12BN.SS-(D12Hmgc3-D12Rat79)/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (for 77 days) then controlled sodium content diet (8 %) (for 7 days) |
Flister MJ, et al., Hypertension. 2012 Oct;60(4):942-8. doi: 10.1161/HYPERTENSIONAHA.112.198200. Epub 2012 Aug 6. |
arterial blood pressure trait |
male |
74 days-84 days |
8 |
|
serial mean |
139.0 |
mmHg |
2.0 |
5.66 |
intra-aortic abdominal radiotelemetry |
|
14400.0 |
|
0 |
|
abdominal aorta |
4 hrs for 3 consecutive days |
|
96867 |
1718 |
SS-Chr 12BN/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (0.3 %) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
arterial blood pressure trait |
male |
66 days-73 days |
11 |
|
serial mean |
111.0 |
mmHg |
1.0 |
3.32 |
intra-aortic abdominal radiotelemetry |
|
14400.0 |
|
0 |
|
abdominal aorta |
4 hrs for 3 consecutive days |
|
96870 |
1719 |
SS/Jr |
absolute change in mean arterial blood pressure |
sodium ion solution (800 mmol/l) (for 4 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
arterial blood pressure trait |
male |
43 days-51 days |
0 |
|
|
17.0 |
mmHg |
2.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
1min measurement per 30min, 24 hr average |
|
68138 |
344 |
SS.LEW-(D17Chm131-D17Chm93)(D10Chm10-D10Rat11)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
146.0 |
mmHg |
3.0 |
6.71 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84494 |
1438 |
SS.LEW-(D1Uia4-D1Rat320)(D10Chm10-D10Rat11)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
6 |
|
|
138.0 |
mmHg |
5.0 |
12.25 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84500 |
1438 |
SS.MNS-(D2Chm33-Tm2sf1),LEW-(D10Rat194-D10Chm243),LEW-(D10Chm10-D10Rat11)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
148.0 |
mmHg |
9.0 |
20.12 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84508 |
1438 |
LEW/Crlc |
percent change in heart rate |
sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
7.0 |
% |
1.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
|
|
69738 |
344 |
SS.MNS-(D2Chm90-D2Rat38)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
10 |
|
|
138.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70481 |
1438 |
SS-Chr 12BN/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (between 42 and 49 days) |
Prisco SZ, et al., Hypertension. 2014 Jul 7. pii: HYPERTENSIONAHA.114.03550. |
arterial blood pressure trait |
male |
71 days-77 days |
25 |
|
|
109.0 |
mmHg |
1.0 |
5.0 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
96802 |
1698 |
LEW.SS-(D7Rat27-D7Mgh1)(D17Rat15-D17Rat51)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 41 days) |
Crespo K, et al., Circ Cardiovasc Genet. 2015 Aug;8(4):610-7. doi: 10.1161/CIRCGENETICS.114.000965. Epub 2015 May 11. |
arterial blood pressure trait |
male |
67 days-77 days |
5 |
|
|
94.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
864000.0 |
|
0 |
|
|
|
|
97144 |
1878 |
SS-Nppbem2Mcwi-/- |
mean arterial blood pressure |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
133.0 |
mmHg |
2.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98398 |
2059 |
SS-Renem1Mcwi-/- |
systolic blood pressure |
controlled sodium content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
arterial blood pressure trait |
male |
66 days-69 days |
4 |
|
serial mean |
76.38 |
mmHg |
2.94 |
5.88 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98388 |
2038 |
SHRSP/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
151.6 |
mmHg |
3.9 |
6.75 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65661 |
613 |
SS/Jr |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
67 days-69 days |
5 |
|
|
181.0 |
mmHg |
3.6 |
8.05 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65041 |
283 |
SS/Jr |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
147 days-149 days |
1 |
|
|
219.7 |
mmHg |
1.7 |
1.7 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65053 |
283 |
SS.SR-(D3Arb14-D3Mco36)/Mco |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
147 days-149 days |
2 |
|
|
228.2 |
mmHg |
3.0 |
4.24 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65054 |
283 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
155.8 |
mmHg |
3.7 |
6.41 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65698 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
130.6 |
mmHg |
8.2 |
14.2 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65713 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
108.4 |
mmHg |
1.4 |
2.42 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65715 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
124.3 |
mmHg |
1.6 |
2.77 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65719 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
98.3 |
mmHg |
4.2 |
7.27 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65633 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
98.4 |
mmHg |
5.7 |
9.87 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65649 |
613 |
SHRSP/Gcrc |
systolic blood pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
124 days-128 days |
6 |
|
continuous mean |
197.9 |
mmHg |
4.04 |
9.9 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11621 |
109 |
WKY/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
137 days-140 days |
6 |
|
continuous mean |
101.2 |
mmHg |
3.02 |
7.4 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11637 |
109 |
SS.SHR-(D9Wox16-D9Rat64)/Mco |
systolic blood pressure |
controlled sodium content diet (2 %) (between 35 and 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
arterial blood pressure trait |
male |
75 days-79 days |
5 |
|
serial mean |
147.0 |
mmHg |
1.56 |
3.49 |
intra-aortic abdominal radiotelemetry |
lower abdominal aorta |
172800 |
|
0 |
|
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 12 4-hour averages over 48 hours using 5 or 6 rats |
|
13027 |
305 |
SS/Jr |
diastolic blood pressure |
controlled sodium content diet (2 %) (between 34 and 38 days) |
Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. |
arterial blood pressure trait |
male |
73 days-80 days |
8 |
|
|
147.0 |
mmHg |
5.5 |
15.56 |
intra-aortic abdominal radiotelemetry |
|
10 |
|
0 |
|
|
average of 24 hr |
|
65494 |
611 |
SS.LEW-(D1Rat211-D1Rat18)/Mco |
pulse pressure |
controlled sodium content diet (2 %) (between 34 and 38 days) |
Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. |
arterial blood pressure trait |
male |
73 days-80 days |
8 |
|
|
49.0 |
mmHg |
0.74 |
2.09 |
intra-aortic abdominal radiotelemetry |
|
10 |
|
0 |
|
|
average of 24 hr |
|
65500 |
611 |
SS.LEW-(D1Rat211-D1Rat18)/Mco |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 34 and 38 days) |
Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. |
arterial blood pressure trait |
male |
73 days-80 days |
8 |
|
|
146.0 |
mmHg |
3.1 |
8.77 |
intra-aortic abdominal radiotelemetry |
|
10 |
|
0 |
|
|
average of 24 hr |
|
65501 |
611 |
SS.LEW-(D10Rat24-Igfbp4)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) |
Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. |
arterial blood pressure trait |
male |
66 days-78 days |
7 |
|
serial mean |
177.0 |
mmHg |
6.0 |
15.87 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1036800 |
|
0 |
|
telemetry probe model PA-D70, Data Sciences, St. Paul, MN |
average of 24 hour averages over 12 days |
|
12739 |
304 |
SS.LEW-(D10Mco15-D10Mgh1)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) |
Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. |
arterial blood pressure trait |
male |
66 days-78 days |
6 |
|
serial mean |
180.0 |
mmHg |
6.0 |
14.7 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1036800 |
|
0 |
|
telemetry probe model PA-D70, Data Sciences, St. Paul, MN |
average of 24 hour averages over 12 days |
|
12742 |
304 |
SS.LEW-(D10Chm167-D10Chm257)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) |
Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. |
arterial blood pressure trait |
male |
66 days-78 days |
5 |
|
serial mean |
145.0 |
mmHg |
6.0 |
13.42 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1036800 |
|
0 |
|
telemetry probe model PA-D70, Data Sciences, St. Paul, MN |
average of 24 hour averages over 12 days |
|
12744 |
304 |
SS.LEW-(D10Chm224-D10Chm259)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) |
Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. |
arterial blood pressure trait |
male |
66 days-78 days |
6 |
|
serial mean |
131.0 |
mmHg |
6.0 |
14.7 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1036800 |
|
0 |
|
telemetry probe model PA-D70, Data Sciences, St. Paul, MN |
average of 24 hour averages over 12 days |
|
12747 |
304 |
SS.SHR-(D9Mco74-D9Rat64)/Mco |
diastolic blood pressure |
controlled sodium content diet (2 %) (between 35 and 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
arterial blood pressure trait |
male |
75 days-79 days |
5 |
|
serial mean |
108.0 |
mmHg |
1.32 |
2.95 |
intra-aortic abdominal radiotelemetry |
lower abdominal aorta |
172800 |
|
0 |
|
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 12 4-hour averages over 48 hours using 5 or 6 rats |
|
13033 |
305 |
SR/Jr |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to ambient light |
St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 |
arterial blood pressure trait |
male |
70 days-77 days |
7 |
|
serial mean |
95.0 |
mmHg |
4.0 |
10.58 |
intra-aortic abdominal radiotelemetry |
|
604800.0 |
|
0 |
|
5 s every 5 min daily for a week |
|
|
11698 |
119 |
SS.LEW-(D17Rat65-D17Chm2)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 43 and 47 days) |
Grondin M, et al., Physiol Genomics 2005 Mar 21;21(1):112-6. Epub 2005 Jan 4. |
arterial blood pressure trait |
male |
88 days-92 days |
5 |
|
|
173.0 |
mmHg |
8.0 |
17.89 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
measure every 2 min for 24 hrs |
|
12472 |
261 |
SS.LEW-(D18Rat61-D18Rat45)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8. |
arterial blood pressure trait |
male |
56 days
| 6 |
|
|
141.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
aorta |
|
|
0 |
|
|
|
|
12599 |
269 |
SS.LEW-(D18Chm91-D18Rat67)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8. |
arterial blood pressure trait |
male |
56 days
| 5 |
|
|
142.0 |
mmHg |
4.0 |
8.94 |
intra-aortic abdominal radiotelemetry |
aorta |
|
|
0 |
|
|
|
|
12601 |
269 |
SR/Jr |
systolic blood pressure |
controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to ambient light |
St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 |
arterial blood pressure trait |
male |
70 days-77 days |
7 |
|
serial mean |
138.0 |
mmHg |
4.0 |
10.58 |
intra-aortic abdominal radiotelemetry |
|
604800.0 |
|
0 |
|
5 s every 5 min daily for a week |
|
|
11696 |
119 |
SS.MNS-(D2Chm25-Fgg)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 21 and 37 days) |
Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28. |
arterial blood pressure trait |
male |
56 days-72 days |
9 |
|
|
160.0 |
mmHg |
7.0 |
21.0 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
|
|
12357 |
242 |
WKY/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
99.6 |
mmHg |
3.1 |
5.37 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65592 |
613 |
WKY/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
4 |
|
continuous mean |
91.2 |
mmHg |
6.0 |
12.0 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65594 |
613 |
WKY/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
4 |
|
continuous mean |
95.5 |
mmHg |
6.4 |
12.8 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65595 |
613 |
WKY/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
4 |
|
continuous mean |
127.8 |
mmHg |
7.9 |
15.8 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65598 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
164.3 |
mmHg |
1.9 |
3.29 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65602 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
146.4 |
mmHg |
3.7 |
6.41 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65605 |
613 |
SS.LEW-(D10Rat194-D10Chm243)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
10 |
|
|
151.0 |
mmHg |
3.0 |
9.49 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70435 |
1438 |
SS.LEW-(D8Rat56-D8Rat51)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
9 |
|
|
197.0 |
mmHg |
5.0 |
15.0 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70440 |
1438 |
SS.LEW-(D2Rat199-D2Mco17)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
199.0 |
mmHg |
4.0 |
11.31 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70446 |
1438 |
SS.LEW-(D18Chm41-D18Rat92)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
124.0 |
mmHg |
4.0 |
8.94 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70448 |
1438 |
SS.LEW-(D5Mit5-D5M4Mit14)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
9 |
|
|
180.0 |
mmHg |
8.0 |
24.0 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70473 |
1438 |
SS.LEW-(D1Uia4-D1Rat320)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
10 |
|
|
134.0 |
mmHg |
7.0 |
22.14 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70451 |
1438 |
SS |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
15 |
|
|
177.0 |
mmHg |
4.0 |
15.49 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70463 |
1438 |
SS |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
16 |
|
|
184.0 |
mmHg |
4.0 |
16.0 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70464 |
1438 |
SS.LEW-(D3Rat52-D3Rat130)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
7 |
|
|
141.0 |
mmHg |
6.0 |
15.87 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70472 |
1438 |
SS.MNS-(D2Rat183-D2Chm113)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
14 |
|
|
145.0 |
mmHg |
3.0 |
11.22 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70460 |
1438 |
SS.LEW-(D2Rat199-D2Mco17)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
204.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70479 |
1438 |
SS.LEW-(D17Chm14-D17Rat181)/Ayd |
absolute change in mean arterial blood pressure |
sodium ion solution (800 mmol/l) (for 4 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
arterial blood pressure trait |
male |
43 days-51 days |
0 |
|
|
15.0 |
mmHg |
1.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
1min measurement per 30min, 24 hr average |
|
68137 |
344 |
SS.LEW-(D10Chm10-D10Rat11)/Ayd |
absolute change in heart rate |
sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
31.0 |
beats/min |
3.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
|
|
69735 |
344 |
SS.LEW-(D10Chm10-D10Rat11)/Ayd |
percent change in heart rate |
sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
7.0 |
% |
0.4 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
|
|
69739 |
344 |
SS/Jr |
maximum change in heart rate to change in mean arterial blood pressure ratio |
sodium ion solution (800 mmol/l) (for 4 days) then phenylephrine (5-50 ug/min) then sodium nitroprusside (10-100 ug/min) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
-1.8 |
beats/min/mmHg |
0.2 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
Maximum slope, bpm/mm Hg |
|
69745 |
344 |
SS.LEW-(D10Chm10-D10Rat11)/Ayd |
change in heart rate to change in mean arterial blood pressure ratio |
sodium ion solution (800 mmol/l) (for 4 days) then phenylephrine (5-50 ug/min) then sodium nitroprusside (10-100 ug/min) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
-2.2 |
beats/min/mmHg |
0.1 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
average slope, bpm/mm Hg |
|
69747 |
344 |
SS.MNS-(D2Rat155-D2Chm419)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
7 |
|
|
133.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70482 |
1438 |
SS.LEW-(D10Rat27-Igfbp4)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
148.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70488 |
1438 |
SS/Jr |
mean arterial blood pressure |
controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14. |
arterial blood pressure trait |
male |
56 days-59 days |
16 |
|
|
177.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
|
86400.0 |
|
0 |
|
|
|
|
68086 |
830 |
SS/JrHsd |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. |
arterial blood pressure trait |
female |
108 days-112 days |
9 |
|
|
139.7 |
mmHg |
5.8 |
17.4 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70354 |
1358 |
SS/JrHsd |
mean arterial blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. |
arterial blood pressure trait |
female |
108 days-112 days |
9 |
|
|
165.9 |
mmHg |
5.9 |
17.7 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70357 |
1358 |
SS.SR-(rs106870553-rs63922710)/Opaz |
systolic blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
female |
108 days-112 days |
10 |
|
|
187.0 |
mmHg |
3.0 |
9.49 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70566 |
1458 |
SS.SR-(rs106870553-rs63922710)/Opaz |
pulse pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
female |
108 days-112 days |
10 |
|
|
51.84 |
mmHg |
1.4 |
4.43 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70569 |
1458 |
SS.LEW-(D7Rat73-D7Rat128)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
6 |
|
|
138.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70454 |
1438 |
SS.MNS-(D2Chm90-D2Rat38)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
144.0 |
mmHg |
4.0 |
11.31 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70455 |
1438 |
SS.LEW-(D17Rat84-D17Chm17)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
137.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70496 |
1438 |
SS/JrHsd |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 83 and 84 days) |
Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23. |
arterial blood pressure trait |
female |
167 days-168 days |
8 |
|
|
143.0 |
mmHg |
4.88 |
13.8 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
67871 |
810 |
SS.SR-(D2Rat352-rs63922710)/Opaz |
systolic blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
male |
108 days-112 days |
6 |
|
|
180.8 |
mmHg |
3.7 |
9.06 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70562 |
1458 |
SS.SR-(D2Rat352-rs63922710)/Opaz |
mean arterial blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
male |
108 days-112 days |
6 |
|
|
153.7 |
mmHg |
3.1 |
7.59 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70564 |
1458 |
SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (for 77 days) then controlled sodium content diet (8 %) (for 7 days) |
Flister MJ, et al., Hypertension. 2012 Oct;60(4):942-8. doi: 10.1161/HYPERTENSIONAHA.112.198200. Epub 2012 Aug 6. |
arterial blood pressure trait |
male |
74 days-84 days |
11 |
|
serial mean |
178.0 |
mmHg |
7.0 |
23.22 |
intra-aortic abdominal radiotelemetry |
|
14400.0 |
|
0 |
|
abdominal aorta |
4 hrs for 3 consecutive days |
|
96869 |
1718 |
SS-Chr 12BN.SS-(D12Hmgc3-D12Rat79)/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (for 77 days) |
Flister MJ, et al., Hypertension. 2012 Oct;60(4):942-8. doi: 10.1161/HYPERTENSIONAHA.112.198200. Epub 2012 Aug 6. |
arterial blood pressure trait |
male |
67 days-77 days |
8 |
|
serial mean |
119.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
14400.0 |
|
0 |
|
abdominal aorta |
4 hrs for 3 consecutive days |
|
96866 |
1718 |
SS.LEW-(D10Rat194-D10Chm243)(D10Chm10-D10Rat11)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
109.0 |
mmHg |
8.0 |
17.89 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84485 |
1438 |
SS.LEW-(D2Uia5-D2Mit6)(D10Chm10-D10Rat11)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
157.0 |
mmHg |
7.0 |
15.65 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84496 |
1438 |
SS.LEW-(D2Uia5-D2Mit6)(D3Rat17-D3Mco80)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
116.0 |
mmHg |
3.0 |
6.71 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84499 |
1438 |
SS.MNS-(D2Chm90-D2Rat38),LEW-(D10Chm10-D10Rat11)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
133.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84504 |
1438 |
SS.MNS-(D2Rat155-D2Chm419),LEW-(D10Rat194-D10Chm243)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
135.0 |
mmHg |
5.0 |
11.18 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84506 |
1438 |
SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (1 %) (between 42 and 49 days) |
Prisco SZ, et al., Hypertension. 2014 Jul 7. pii: HYPERTENSIONAHA.114.03550. |
arterial blood pressure trait |
male |
71 days-77 days |
14 |
|
|
110.0 |
mmHg |
2.0 |
7.48 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
96801 |
1698 |
SS.LEW-(D10Chm280-D10Chm216)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 35 and 105 days) |
Crespo K, et al., J Hypertens. 2013 May;31(5):927-35. doi: 10.1097/HJH.0b013e32835edc7e. |
arterial blood pressure trait |
male |
66 days-86 days |
12 |
|
serial mean |
149.0 |
mmHg |
1.15 |
4.0 |
intra-aortic abdominal radiotelemetry |
|
2.0 |
|
0 |
|
|
for 2 wks |
has records that will be duplicated if entered need to add multiple refs once the functionality is in |
96579 |
1665 |
WKY/NCrl |
systolic blood pressure |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133 days-140 days |
6 |
|
|
121.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 1 week |
daytime measurement |
|
103522 |
2827 |
GK |
systolic blood pressure |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133 days-140 days |
5 |
|
|
134.0 |
mmHg |
4.0 |
8.94 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 1 week |
daytime measurement |
|
103525 |
2827 |
WKY/NCrl |
systolic blood pressure |
salidroside (40 mg/kg) (for 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168 days
| 6 |
|
|
117.0 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 4 weeks |
daytime measurement |
|
103527 |
2827 |
WKY/NCrl |
systolic blood pressure |
control condition and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133 days-140 days |
6 |
|
|
126.0 |
mmHg |
4.0 |
9.8 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/night for 1 week |
nighttime measurement |
|
103530 |
2827 |
WKY/NCrl |
systolic blood pressure |
control condition and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133 days-140 days |
6 |
|
|
122.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/night for 1 week |
nighttime measurement |
|
103531 |
2827 |
SS-Agtrapem4Mcwi-/- |
heart rate |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
heart pumping trait |
male |
58 days-67 days |
0 |
|
serial mean |
350.0 |
beats/min |
6.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98423 |
2059 |
WKY/NCrl |
systolic blood pressure |
vehicle control condition (for 28 days) and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168 days
| 6 |
|
|
126.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/night for 4 weeks |
nighttime measurement |
|
103534 |
2827 |
GK |
systolic blood pressure |
vehicle control condition (for 28 days) and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168 days
| 6 |
|
|
145.0 |
mmHg |
4.0 |
9.8 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/night for 4 weeks |
nighttime measurement |
|
103536 |
2827 |
WKY/NCrl |
diastolic blood pressure |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133 days-140 days |
6 |
|
|
85.0 |
mmHg |
4.0 |
9.8 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/day for 1 week |
daytime measurement |
|
103538 |
2827 |
WKY/NCrl |
diastolic blood pressure |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133 days-140 days |
6 |
|
|
82.0 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/day for 1 week |
daytime measurement |
|
103539 |
2827 |
GK |
diastolic blood pressure |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133 days-140 days |
5 |
|
|
95.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/day for 1 week |
daytime measurement |
|
103541 |
2827 |
WKY/NCrl |
diastolic blood pressure |
vehicle control condition (for 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168 days
| 6 |
|
|
85.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 4 weeks |
daytime measurement |
|
103542 |
2827 |
WKY/NCrl |
diastolic blood pressure |
control condition and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133 days-140 days |
6 |
|
|
89.0 |
mmHg |
4.0 |
9.8 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/night for 1 week |
nighttime measurement |
|
103546 |
2827 |
WKY/NCrl |
heart rate |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
heart pumping trait |
male |
130 days-140 days |
6 |
|
|
290.0 |
beats/min |
4.0 |
9.8 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
measured 12 hr/day for 1 week |
daytime measurement |
|
103554 |
2827 |
WKY/NCrl |
heart rate |
vehicle control condition (for 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
heart pumping trait |
male |
168 days
| 6 |
|
|
294.0 |
beats/min |
5.0 |
12.25 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 4 weeks |
daytime measurement |
|
103558 |
2827 |
GK |
heart rate |
salidroside (40 mg/kg) (for 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
heart pumping trait |
male |
168 days
| 5 |
|
|
289.0 |
beats/min |
5.0 |
11.18 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 4 weeks |
daytime measurement |
|
103561 |
2827 |
WKY/NCrl |
number of spontaneous locomotor movements per unit time |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
voluntary movement trait |
male |
140 days
| 6 |
|
|
1.0 |
/min |
0.2 |
0.49 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
number of spontaneous locomotor movements per unit time (CMO:0003644) |
|
103570 |
2827 |
GK |
number of spontaneous locomotor movements per unit time |
vehicle control condition (between 1 and 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
voluntary movement trait |
male |
168 days
| 6 |
|
|
0.9 |
/min |
0.1 |
0.24 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 4 weeks |
number of spontaneous locomotor movements per unit time (CMO:0003644) |
|
103576 |
2827 |
GK |
number of spontaneous locomotor movements per unit time |
salidroside (40 mg/kg) (between 1 and 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
voluntary movement trait |
male |
168 days
| 5 |
|
|
1.0 |
/min |
0.1 |
0.22 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
measured 12 hr/day for 4 weeks |
number of spontaneous locomotor movements per unit time (CMO:0003644) |
|
103577 |
2827 |
SS/Hsd |
diastolic blood pressure |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
123.0 |
mmHg |
3.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98410 |
2059 |
SS-Agtrapem4Mcwi-/- |
mean arterial blood pressure |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
arterial blood pressure trait |
male |
58 days-67 days |
0 |
|
serial mean |
131.0 |
mmHg |
3.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98402 |
2059 |
SS-Renem1Mcwi-/- |
diastolic blood pressure |
controlled sodium content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
arterial blood pressure trait |
male |
66 days-69 days |
8 |
|
serial mean |
46.44 |
mmHg |
2.34 |
6.62 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98381 |
2038 |
SS-Renem1Mcwi+/+ |
mean arterial blood pressure |
controlled sodium content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
arterial blood pressure trait |
female |
66 days-69 days |
7 |
|
serial mean |
112.8 |
mmHg |
3.55 |
9.39 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98383 |
2038 |
SS-Renem1Mcwi+/+ |
diastolic blood pressure |
controlled sodium content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
arterial blood pressure trait |
female |
66 days-69 days |
7 |
|
serial mean |
89.42 |
mmHg |
3.12 |
8.25 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98384 |
2038 |
SS-Renem1Mcwi+/- |
mean arterial blood pressure |
controlled sodium content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
arterial blood pressure trait |
female |
66 days-69 days |
8 |
|
serial mean |
115.55 |
mmHg |
1.5 |
4.24 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98386 |
2038 |
SS-Renem1Mcwi+/- |
heart rate |
controlled sodium content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
heart pumping trait |
female |
66 days-69 days |
8 |
|
serial mean |
390.95 |
beats/min |
11.68 |
33.04 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98395 |
2038 |
WI-Mc4rm1Hubr |
diastolic blood pressure |
control condition |
Stepp DW, et al., Physiol Rep. 2013 Nov;1(6):e00146. doi: 10.1002/phy2.146. Epub 2013 Nov 13. |
arterial blood pressure trait |
male |
70 days-126 days |
8 |
every 10 min for 24hr |
|
94.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
105539 |
3017 |
Crl:WI |
systolic blood pressure |
control condition |
Stepp DW, et al., Physiol Rep. 2013 Nov;1(6):e00146. doi: 10.1002/phy2.146. Epub 2013 Nov 13. |
arterial blood pressure trait |
male |
70 days-126 days |
8 |
every 10 min for 24hr |
|
129.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
105540 |
3017 |
WI-Mc4rm1Hubr |
systolic blood pressure |
control condition |
Stepp DW, et al., Physiol Rep. 2013 Nov;1(6):e00146. doi: 10.1002/phy2.146. Epub 2013 Nov 13. |
arterial blood pressure trait |
male |
70 days-126 days |
8 |
every 10 min for 24hr |
|
130.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
105541 |
3017 |
Crl:WI |
mean arterial blood pressure |
control condition |
Stepp DW, et al., Physiol Rep. 2013 Nov;1(6):e00146. doi: 10.1002/phy2.146. Epub 2013 Nov 13. |
arterial blood pressure trait |
male |
70 days-126 days |
8 |
day every 10 min |
|
110.0 |
mmHg |
3.0 |
8.49 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
105542 |
3017 |
SS.MNS-(D2Mit6-Adh1)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 21 and 37 days) |
Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28. |
arterial blood pressure trait |
male |
56 days-72 days |
5 |
|
|
120.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
none |
|
12323 |
242 |
WKY/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
4 |
|
continuous mean |
117.7 |
mmHg |
7.5 |
15.0 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65671 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
161.6 |
mmHg |
5.4 |
9.35 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65677 |
613 |
SHRSP/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
229.8 |
mmHg |
7.3 |
12.64 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65651 |
613 |
WKY/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
92.0 |
mmHg |
2.9 |
5.02 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65668 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
148.9 |
mmHg |
3.5 |
6.06 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65626 |
613 |
SS.SHR-(D9Mco74-D9Rat64)/Mco |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 35 and 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
arterial blood pressure trait |
male |
75 days-79 days |
5 |
|
serial mean |
132.0 |
mmHg |
1.53 |
3.42 |
intra-aortic abdominal radiotelemetry |
lower abdominal aorta |
172800 |
|
0 |
|
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 12 4-hour averages over 48 hours using 5 or 6 rats |
|
13037 |
305 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
167.6 |
mmHg |
5.5 |
9.53 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65688 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
140.7 |
mmHg |
8.0 |
13.86 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65700 |
613 |
SS.LEW-(D18Chm41-D18Rat92)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8. |
arterial blood pressure trait |
male |
56 days
| 5 |
|
|
124.0 |
mmHg |
4.0 |
8.94 |
intra-aortic abdominal radiotelemetry |
aorta |
|
|
0 |
|
|
|
|
12600 |
269 |
SS.LEW-(D18Rat29-D18Rat55)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8. |
arterial blood pressure trait |
male |
56 days
| 11 |
|
|
148.0 |
mmHg |
4.0 |
13.27 |
intra-aortic abdominal radiotelemetry |
aorta |
|
|
0 |
|
|
|
|
12607 |
269 |
LEW/Crlc |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8. |
arterial blood pressure trait |
male |
56 days
| 6 |
|
|
94.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
aorta |
0.0 |
|
0 |
|
|
|
|
12590 |
269 |
SS.SR-(rs65785750-rs106808193)/Opaz |
systolic blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. |
arterial blood pressure trait |
female |
108 days-112 days |
8 |
|
|
167.9 |
mmHg |
3.2 |
9.05 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70353 |
1358 |
SS.SR-(rs65785750-rs106808193)/Opaz |
mean arterial blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. |
arterial blood pressure trait |
female |
108 days-112 days |
8 |
|
|
140.8 |
mmHg |
3.1 |
8.77 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70359 |
1358 |
WKY/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
4 |
|
continuous mean |
103.4 |
mmHg |
6.7 |
13.4 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65590 |
613 |
WKY/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
128.0 |
mmHg |
3.3 |
5.72 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65601 |
613 |
SS/Jr |
systolic blood pressure |
controlled sodium content diet (2 %) (between 35 and 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
arterial blood pressure trait |
male |
75 days-79 days |
5 |
|
serial mean |
185.0 |
mmHg |
1.97 |
4.41 |
intra-aortic abdominal radiotelemetry |
lower abdominal aorta |
172800 |
|
0 |
|
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 12 4-hour averages over 48 hours using 5 or 6 rats |
|
13026 |
305 |
ACI.FHH-(D1Mit18-D1Rat90)(D3Rat6-D3Got149)(D14Mit11-D14Rat33)(D14Rat65-D14Rat90)/Mcwi |
mean arterial blood pressure |
right nephrectomy (for 35 days) then controlled sodium content diet (0.4 %) (for 35 days) |
O'Meara CC, et al., J Am Soc Nephrol. 2011 Mar;22(3):518-25. Epub 2010 Dec 2. |
arterial blood pressure trait |
male |
70 days-77 days |
7 |
|
serial mean |
110.82 |
mmHg |
3.45 |
9.13 |
intra-aortic abdominal radiotelemetry |
|
259200.0 |
right nephrectomy |
35 |
days |
10 s every 2 m for 3 h |
|
|
84744 |
1600 |
SS.SR-(D2Rat352-rs63922710)/Opaz |
pulse pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
female |
108 days-112 days |
6 |
|
|
50.0 |
mmHg |
1.0 |
2.45 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70561 |
1458 |
SS.SR-(rs106870553-rs63922710)/Opaz |
mean arterial blood pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
female |
108 days-112 days |
10 |
|
|
159.6 |
mmHg |
2.8 |
8.85 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
70567 |
1458 |
SS.LEW-(D3Rat52-D3Rat130)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
7 |
|
|
144.0 |
mmHg |
5.0 |
13.23 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70442 |
1438 |
SS.LEW-(D17Rat84-D17Chm17)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
151.0 |
mmHg |
7.0 |
19.8 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70445 |
1438 |
SS.LEW-(D16Chm48-D16Chm60)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
7 |
|
|
134.0 |
mmHg |
5.0 |
13.23 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70447 |
1438 |
SS |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
18 |
|
|
172.0 |
mmHg |
4.0 |
16.97 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70471 |
1438 |
SS.MNS-(D2Chm25-Fgg)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
9 |
|
|
160.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70477 |
1438 |
SS.LEW-(D3Rat61-D3Wox1)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
5 |
|
|
123.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70449 |
1438 |
SS.LEW-(D10Chm10-D10Rat11)/Ayd |
absolute change in mean arterial blood pressure |
sodium ion solution (800 mmol/l) (for 14 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
arterial blood pressure trait |
male |
53 days-61 days |
0 |
|
|
7.0 |
mmHg |
1.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
1min measurement per 30min, 24 hr average |
|
68140 |
344 |
SS/Jr |
absolute change in mean arterial blood pressure |
sodium ion solution (800 mmol/l) (for 14 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
arterial blood pressure trait |
male |
53 days-61 days |
0 |
|
|
13.0 |
mmHg |
1.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
1min measurement per 30min, 24 hr average |
|
68142 |
344 |
SS.LEW-(D3Rat2-D3Chm79)(D10Rat194-D10Chm243)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
12 |
|
|
136.0 |
mmHg |
3.0 |
10.39 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
84492 |
1438 |
SS.LEW-(D17Chm14-D17Rat181)/Ayd |
absolute change in mean arterial blood pressure |
sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
arterial blood pressure trait |
male |
53 days-61 days |
0 |
|
|
20.0 |
mmHg |
2.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
|
|
69728 |
344 |
SS.LEW-(D17Chm14-D17Rat181)/Ayd |
absolute change in heart rate |
sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
42.0 |
beats/min |
3.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
|
|
69736 |
344 |
SS.LEW-(D17Chm14-D17Rat181)/Ayd |
maximum change in heart rate to change in mean arterial blood pressure ratio |
sodium ion solution (800 mmol/l) (for 4 days) then phenylephrine (5-50 ug/min) then sodium nitroprusside (10-100 ug/min) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
-1.9 |
beats/min/mmHg |
0.2 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
Maximum slope, bpm/mm Hg |
|
69744 |
344 |
SS.LEW-(D17Chm14-D17Rat181)/Ayd |
change in heart rate to change in mean arterial blood pressure ratio |
sodium ion solution (800 mmol/l) (for 4 days) then phenylephrine (5-50 ug/min) then sodium nitroprusside (10-100 ug/min) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
heart pumping trait |
male |
53 days-61 days |
0 |
|
|
-1.7 |
beats/min/mmHg |
0.2 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
average slope, bpm/mm Hg |
|
69748 |
344 |
SS-Renem1Mcwi-/- |
diastolic blood pressure |
controlled sodium content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
arterial blood pressure trait |
female |
66 days-69 days |
4 |
|
serial mean |
49.1 |
mmHg |
2.61 |
5.22 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98390 |
2038 |
SS-Renem1Mcwi+/+ |
heart rate |
controlled sodium content diet (0.4 %) (between 66 and 69 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
heart pumping trait |
female |
66 days-69 days |
7 |
|
serial mean |
386.01 |
beats/min |
5.71 |
15.11 |
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98394 |
2038 |
SS-Mthfrem1Mcwi-/+ |
heart rate |
controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) |
Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. |
heart pumping trait |
male |
58 days-67 days |
0 |
|
serial mean |
330.0 |
beats/min |
12.0 |
|
intra-aortic abdominal radiotelemetry |
|
32400.0 |
|
0 |
|
|
|
|
98422 |
2059 |
SS/Jr |
absolute change in systolic blood pressure |
controlled sodium content diet (2 %) (between 34 and 38 days) then controlled exposure to darkness then controlled exposure to ambient light |
Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. |
arterial blood pressure trait |
male |
73 days-80 days |
8 |
|
|
22.6 |
mmHg |
1.05 |
2.97 |
intra-aortic abdominal radiotelemetry |
|
10 |
|
0 |
|
|
diurnal difference |
|
65497 |
611 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
103.5 |
mmHg |
3.0 |
5.2 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65609 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
182.0 |
mmHg |
6.9 |
11.95 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65616 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
127.5 |
mmHg |
5.7 |
9.87 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65619 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
141.2 |
mmHg |
4.7 |
8.14 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65622 |
613 |
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
94.1 |
mmHg |
3.8 |
6.58 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65632 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
137.9 |
mmHg |
2.6 |
4.5 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65638 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
141.5 |
mmHg |
2.0 |
3.46 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65640 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
120.4 |
mmHg |
8.1 |
14.03 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65641 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
95.1 |
mmHg |
1.6 |
2.77 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65642 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
87.4 |
mmHg |
4.5 |
7.79 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65645 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
mean arterial blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
94.1 |
mmHg |
3.8 |
6.58 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65648 |
613 |
SHRSP/Gcrc |
systolic blood pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
male |
124 days-128 days |
7 |
|
continuous mean |
250.5 |
mmHg |
4.12 |
10.9 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11620 |
109 |
WKY/Gcrc |
diastolic blood pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
124 days-128 days |
6 |
|
continuous mean |
99.5 |
mmHg |
1.96 |
4.8 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11627 |
109 |
SHRSP/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
137 days-140 days |
6 |
|
continuous mean |
214.3 |
mmHg |
5.88 |
14.4 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11632 |
109 |
WKY/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
male |
137 days-140 days |
6 |
|
continuous mean |
168.7 |
mmHg |
2.25 |
5.5 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11633 |
109 |
SHRSP/Gcrc |
pulse pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
137 days-140 days |
6 |
|
continuous mean |
63.8 |
mmHg |
1.63 |
4.0 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11638 |
109 |
WKY/Gcrc |
pulse pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
male |
137 days-140 days |
6 |
|
continuous mean |
52.9 |
mmHg |
1.51 |
3.7 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11639 |
109 |
SR/Jr |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to darkness |
St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 |
arterial blood pressure trait |
female |
56 days-63 days |
8 |
|
serial mean |
89.0 |
mmHg |
1.0 |
2.83 |
intra-aortic abdominal radiotelemetry |
|
604800.0 |
|
0 |
|
5 s every 5 min nightly for a week |
|
|
11701 |
119 |
LEW/Crlc |
absolute change in mean arterial blood pressure |
sodium ion solution (800 mmol/l) (for 4 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
arterial blood pressure trait |
male |
43 days-51 days |
0 |
|
|
8.0 |
mmHg |
1.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
1min measurement per 30min, 24 hr average |
|
13341 |
344 |
WKY.SHRSP-(D1Rat200-D1Rat216)/Bbb |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 12 days) |
Monti J, et al., Hum Mol Genet 2003 Feb 15;12(4):435-9. |
arterial blood pressure trait |
male |
110 days-124 days |
12 |
|
|
92.94 |
mmHg |
1.11 |
3.85 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
|
|
12658 |
281 |
WKY.SHRSP-(Shbg-Atp1b2)/Bbb |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 12 days) |
Monti J, et al., Hum Mol Genet 2003 Feb 15;12(4):435-9. |
arterial blood pressure trait |
male |
110 days-124 days |
33 |
|
|
91.08 |
mmHg |
0.87 |
5.0 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
|
|
12660 |
281 |
WKY.SHRSP-(D1Rat200-D1Rat216)(Shbg-Atp1b2)/Bbb |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 12 days) |
Monti J, et al., Hum Mol Genet 2003 Feb 15;12(4):435-9. |
arterial blood pressure trait |
male |
110 days-124 days |
10 |
|
|
96.86 |
mmHg |
1.09 |
3.45 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
|
|
12662 |
281 |
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
67 days-69 days |
5 |
|
|
137.8 |
mmHg |
1.6 |
3.58 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65042 |
283 |
SS.SR-(D3Arb14-D3Mco36)/Mco |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
76 days-78 days |
6 |
|
|
169.6 |
mmHg |
2.1 |
5.14 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65045 |
283 |
SS/Jr |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
107 days-109 days |
3 |
|
|
228.2 |
mmHg |
2.6 |
4.5 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65047 |
283 |
SS/Jr |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
114 days-116 days |
3 |
|
|
219.3 |
mmHg |
4.2 |
7.27 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65050 |
283 |
SS.SR-(D3Arb14-D3Mco36)/Mco |
systolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
114 days-116 days |
4 |
|
|
223.7 |
mmHg |
4.6 |
9.2 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65051 |
283 |
SS.SR-(D3Arb14-D3Mco36)/Mco |
diastolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
67 days-69 days |
6 |
|
|
97.9 |
mmHg |
1.4 |
3.43 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65059 |
283 |
SS.SR-(D3Arb14-D3Mco36)/Mco |
diastolic blood pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
arterial blood pressure trait |
male |
76 days-78 days |
6 |
|
|
115.7 |
mmHg |
1.8 |
4.41 |
intra-aortic abdominal radiotelemetry |
|
86400 |
|
0 |
|
|
|
|
65061 |
283 |
SHRSP/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
173.4 |
mmHg |
3.9 |
6.75 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65652 |
613 |
SHRSP/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
188.1 |
mmHg |
5.9 |
10.22 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65659 |
613 |
WKY/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
131.7 |
mmHg |
3.2 |
5.54 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65664 |
613 |
WKY/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
4 |
|
continuous mean |
110.0 |
mmHg |
7.0 |
14.0 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65670 |
613 |
WKY/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
112.2 |
mmHg |
2.7 |
4.68 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65673 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
131.2 |
mmHg |
5.5 |
9.53 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65678 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
115.4 |
mmHg |
4.4 |
7.62 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65681 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
147.8 |
mmHg |
4.3 |
7.45 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65682 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
221.3 |
mmHg |
15.4 |
26.67 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65687 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
176.8 |
mmHg |
6.3 |
10.91 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65689 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
117.4 |
mmHg |
3.9 |
6.75 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65692 |
613 |
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to darkness |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
127.9 |
mmHg |
4.0 |
6.93 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Nights (7 PM to 7 AM) |
|
|
65693 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
146.1 |
mmHg |
2.2 |
3.81 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65710 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
diastolic blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
126 days-147 days |
3 |
|
continuous mean |
83.1 |
mmHg |
6.6 |
11.43 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65716 |
613 |
WKY.SHRSP-(Fst-Pklr)/Gcrc |
mean arterial blood pressure |
controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
126 days-147 days |
3 |
|
continuous mean |
115.0 |
mmHg |
1.5 |
2.6 |
intra-aortic abdominal radiotelemetry |
|
1814400 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65718 |
613 |
SS.SHR-(D9Mco72-D9Mco93)/Mco |
systolic blood pressure |
controlled sodium content diet (2 %) (between 35 and 37 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
arterial blood pressure trait |
male |
75 days-79 days |
5 |
|
serial mean |
146.0 |
mmHg |
1.44 |
3.22 |
intra-aortic abdominal radiotelemetry |
lower abdominal aorta |
172800 |
|
0 |
|
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 12 4-hour averages over 48 hours using 5 or 6 rats |
|
13030 |
305 |
LEW/Crlc |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8. |
arterial blood pressure trait |
male |
56 days
| 6 |
|
|
96.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
aorta |
|
|
0 |
|
|
|
|
12617 |
269 |
SS/Jr |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 21 and 37 days) |
Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28. |
arterial blood pressure trait |
male |
56 days-72 days |
10 |
|
|
170.0 |
mmHg |
5.0 |
15.81 |
intra-aortic abdominal radiotelemetry |
|
|
|
0 |
|
|
|
|
12322 |
242 |
SS.MNS-(Mme-D2Rat131)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (between 21 and 37 days) |
Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28. |
arterial blood pressure trait |
male |
56 days-72 days |
5 |
|
|
122.0 |
mmHg |
2.0 |
4.47 |
intra-aortic abdominal radiotelemetry |
|
0 |
|
0 |
|
|
none |
|
12327 |
242 |
SS.LEW-(D10Chm10-D10Rat11)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) |
Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. |
arterial blood pressure trait |
male |
66 days-78 days |
16 |
|
serial mean |
150.0 |
mmHg |
6.0 |
24.0 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1036800 |
|
0 |
|
telemetry probe model PA-D70, Data Sciences, St. Paul, MN |
average of 24 hour averages over 12 days |
|
12741 |
304 |
SS.LEW-(D10Chm246-D10Chm257)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) |
Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. |
arterial blood pressure trait |
male |
66 days-78 days |
10 |
|
serial mean |
151.0 |
mmHg |
6.0 |
18.97 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
1036800 |
|
0 |
|
telemetry probe model PA-D70, Data Sciences, St. Paul, MN |
average of 24 hour averages over 12 days |
|
12745 |
304 |
SR/Jr |
diastolic blood pressure |
controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to darkness |
St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 |
arterial blood pressure trait |
male |
70 days-77 days |
7 |
|
serial mean |
105.0 |
mmHg |
4.0 |
10.58 |
intra-aortic abdominal radiotelemetry |
|
604800.0 |
|
0 |
|
5 s every 5 min nightly for a week |
|
|
11697 |
119 |
SHRSP/Gcrc |
pulse pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
male |
124 days-128 days |
7 |
|
continuous mean |
69.6 |
mmHg |
1.06 |
2.8 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
|
0 |
|
|
|
|
11628 |
109 |
WKY/Bbb |
systolic blood pressure |
controlled sodium content drinking water (1 %) (for 12 days) |
Monti J, et al., Hum Mol Genet 2003 Feb 15;12(4):435-9. |
arterial blood pressure trait |
male |
110 days-124 days |
20 |
|
|
126.13 |
mmHg |
0.55 |
2.46 |
intra-aortic abdominal radiotelemetry |
|
0 |
|
0 |
|
|
|
|
12654 |
281 |
SHRSP/Gcrc |
systolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
178.4 |
mmHg |
2.1 |
3.64 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65579 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
male |
91 days-126 days |
3 |
|
continuous mean |
117.4 |
mmHg |
2.8 |
4.85 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65606 |
613 |
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc |
diastolic blood pressure |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
arterial blood pressure trait |
female |
91 days-126 days |
3 |
|
continuous mean |
100.2 |
mmHg |
2.4 |
4.16 |
intra-aortic abdominal radiotelemetry |
|
3024000 |
|
0 |
|
Days (7 AM to 7 PM) |
|
|
65608 |
613 |
SS.LEW-(D10Wox51-D10Rat27)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (2 %) (for 21 days) |
Charron S, et al., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14. |
arterial blood pressure trait |
male |
56 days-59 days |
5 |
|
|
140.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
|
86400.0 |
|
0 |
|
|
|
|
67878 |
830 |
SS.LEW-(D10Chm246-D10Chm257)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
9 |
|
|
133.0 |
mmHg |
5.0 |
15.0 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70437 |
1438 |
SS.LEW-(D10Rat194-D10Chm243)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
11 |
|
|
144.0 |
mmHg |
2.0 |
6.63 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70450 |
1438 |
SS.LEW-(D1Chm64-D1Rat19)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
16 |
|
|
143.0 |
mmHg |
3.0 |
12.0 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70453 |
1438 |
SS.LEW-(D10Rat24-Igfbp4)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
7 |
|
|
177.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70487 |
1438 |
SS/JrHsd |
systolic blood pressure |
controlled sodium content diet (8 %) (between 83 and 84 days) |
Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23. |
arterial blood pressure trait |
female |
167 days-168 days |
8 |
|
|
199.5 |
mmHg |
6.93 |
19.6 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
|
|
|
67857 |
810 |
SS.MNS-(D2Got93-D2Rat222)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
10 |
|
|
163.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70476 |
1438 |
SS.MNS-(D2Chm254-D2Chm161)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) |
Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. |
arterial blood pressure trait |
male |
66 days-80 days |
8 |
|
|
135.0 |
mmHg |
|
|
intra-aortic abdominal radiotelemetry |
abdominal aorta |
0.0 |
|
0 |
|
|
|
|
70483 |
1438 |
SS.LEW-(D17Chm14-D17Rat181)/Ayd |
absolute change in mean arterial blood pressure |
sodium ion solution (800 mmol/l) (for 14 days) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
arterial blood pressure trait |
male |
53 days-61 days |
0 |
|
|
13.0 |
mmHg |
1.0 |
|
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
0 |
|
blood pressure measured after infusion |
1min measurement per 30min, 24 hr average |
|
68141 |
344 |
SS.LEW-(D10Chm10-D10Rat11)/Ayd |
absolute change in mean arterial blood pressure |
sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours) |
Huang BS, et al., Hypertension. 2007 Apr 9;. |
arterial blood pressure trait |
male |