BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-142 days |
13 |
100.0 |
% |
|
|
necropsy |
0.0 |
0 |
|
saline control group |
111132 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 5-fluorouracil (100 mg/kg) (for 7 days) and interleukin-2 (75000 U/d) (for 4 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-157 days |
15 |
53.0 |
% |
|
|
necropsy |
0.0 |
0 |
one treatment |
5-fluorouracil + interleukin-2 |
111136 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then thymosin alpha-1 (200 ug/kg) (for 4 days) and interleukin-2 (75000 U/d) (for 4 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-147 days |
14 |
100.0 |
% |
|
|
necropsy |
0.0 |
0 |
one treatment |
thymosin alpha-1 + interleukin-2 |
111138 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-144 days |
16 |
100.0 |
% |
|
|
necropsy |
0.0 |
0 |
two treatment regimen |
saline control group |
111154 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 5-fluorouracil (100 mg/kg) (for 7 days) and thymosin alpha-1 (200 ug/kg) (for 4 days) and interleukin-2 (75000 U/d) (for 4 days) then 5-fluorouracil (100 mg/kg) (for 7 days) and thymosin alpha-1 (200 ug/kg) (for 4 days) and interleukin-2 (75000 U/d) (for 4 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-186 days |
21 |
9.5 |
% |
|
|
necropsy |
0.0 |
0 |
two treatments |
5-fluorouracil + thymosin alpha-1 +interleukin-2 |
111157 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then interleukin-2 (75000 U/d) (for 4 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-146 days |
15 |
93.0 |
% |
|
|
necropsy |
0.0 |
0 |
one treatment |
interleukin-2 |
111135 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 5-fluorouracil (100 mg/kg) (for 7 days) and interleukin-2 (75000 U/d) (for 4 days) then 5-fluorouracil (100 mg/kg) (for 7 days) and interleukin-2 (75000 U/d) (for 4 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-164 days |
18 |
22.0 |
% |
|
|
necropsy |
0.0 |
0 |
two treatments |
5-fluorouracil + interleukin-2 |
111156 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 5-fluorouracil (100 mg/kg) (for 7 days) then 5-fluorouracil (100 mg/kg) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-163 days |
18 |
89.0 |
% |
|
|
necropsy |
0.0 |
0 |
two treatment |
fluorouracil 5-FU |
111155 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 5-fluorouracil (100 mg/kg) (for 7 days) and thymosin alpha-1 (200 ug/kg) (for 4 days) and interleukin-2 (75000 U/d) (for 4 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-162 days |
15 |
13.0 |
% |
|
|
necropsy |
0.0 |
0 |
one treatment |
5-fluorouracil + thymosin alpha-1 +interleukin-2 |
111139 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 5-fluorouracil (100 mg/kg) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-146 days |
15 |
93.0 |
% |
|
|
necropsy |
0.0 |
0 |
one treatment |
fluorouracil 5-FU |
111133 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then thymosin alpha-1 (200 ug/kg) (for 4 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-141 days |
14 |
100.0 |
% |
|
|
necropsy |
0.0 |
0 |
one treatment |
thymosin alpha-1 |
111134 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 5-fluorouracil (100 mg/kg) (for 7 days) and thymosin alpha-1 (200 ug/kg) (for 4 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-145 days |
15 |
87.0 |
% |
|
|
necropsy |
0.0 |
0 |
one treatment |
5-fluorouracil + thymosin alpha-1 |
111137 |
3196 |