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Strain |
Phenotype |
Conditions |
Study |
Experiment Name |
Sex |
Age |
# of Animals |
Value |
Units |
SEM |
SD |
Method |
Method Duration |
Post Insult Type |
Post Insult Time Value |
Post Insult Time Unit |
Method Notes |
Clinical Measurement Notes |
Record ID |
Study ID |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
ovariectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
10.67 |
% |
|
1.4 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
pcna index |
68109 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
6.42 |
% |
|
0.99 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
pcna index |
68106 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
2.76 |
% |
|
1.1 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
pcna index |
68108 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
3.55 |
% |
|
0.98 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
pcna index |
68107 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
15.33 |
% |
|
0.74 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
pcna index |
68110 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
12.14 |
% |
|
1.45 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
pcna index |
68105 |
655 |
|