F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
female |
0 days
| 5 |
0.44 |
ng/ml |
0.03 |
0.07 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
67447 |
655 |
SD |
serum testosterone level |
in utero condition (for 7 days) and dibutyl phthalate (850 mg/kg/d) (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
blood testosterone amount |
male |
1 days
| 6 |
0.4 |
ng/ml |
0.05 |
0.13 |
radioimmunoassay |
1.0 |
|
0 |
|
|
98731 |
2158 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
male |
0 days
| 5 |
0.85 |
ng/ml |
0.03 |
0.07 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67443 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
ovariectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
female |
0 days
| 5 |
0.4 |
ng/ml |
0.01 |
0.02 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67451 |
655 |
BluHsd:LE |
serum testosterone level |
vehicle control condition (for 30 days) and controlled in utero environment (for 9 days) then maternal milk (for 21 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
blood testosterone amount |
male |
98 days
| 8 |
7.3 |
ng/ml |
1.5 |
4.24 |
radioimmunoassay |
0.0 |
|
0 |
|
tritium-based |
76252 |
1543 |
SD |
serum testosterone level |
in utero condition (for 7 days) and corn oil (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
blood testosterone amount |
male |
1 days
| 6 |
0.81 |
ng/ml |
0.05 |
0.12 |
radioimmunoassay |
1.0 |
|
0 |
|
|
98732 |
2158 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
female |
0 days
| 5 |
0.42 |
ng/ml |
0.01 |
0.02 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67455 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
male |
0 days
| 5 |
0.95 |
ng/ml |
0.09 |
0.21 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67439 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
male |
0 days
| 5 |
2.0 |
ng/ml |
0.22 |
0.5 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
67435 |
655 |
BluHsd:LE |
serum testosterone level |
vehicle control condition (for 30 days) and controlled in utero environment (for 9 days) then maternal milk (for 21 days) then controlled fat content diet (21.2 %) (for 28 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
blood testosterone amount |
male |
98 days
| 8 |
10.0 |
ng/ml |
1.2 |
3.39 |
radioimmunoassay |
0.0 |
|
0 |
|
tritium-based |
76253 |
1543 |