Phenominer Database Results (494 hits)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
SS.BN-(D13Hmgc1048-D13Hmgc1045)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 23 and 32 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 44 days-53 days 11 serial mean 103.0 mmHg 2.0 6.63 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 carotid a. to thoracic aorta implant strain 26-O 98474 2079
SR/Jr heart weight controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart mass not specified 84 days 5 1.12 g 0.04 0.08 post excision weight measurement 0.0 0 103144 2787
SS/Jr left ventricular systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then pentobarbital, sodium (20 mg/kg) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart left ventricular blood pressure trait not specified 84 days 5 180.0 mmHg 4.47 10.0 vascular transducer tipped catheter 0.0 0 103149 2787
SS/Jr left ventricular end-diastolic blood pressure controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then pentobarbital, sodium (20 mg/kg) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart left ventricular blood pressure trait not specified 84 days 5 3.0 mmHg 0.45 1.0 vascular transducer tipped catheter 0.0 0 103151 2787
SS/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 336.0 beats/min 5.37 12.0 intra-aortic thoracic radiotelemetry 0.0 0 103159 2787
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 102.0 mmHg 0.45 1.0 intra-aortic thoracic radiotelemetry 0.0 0 103166 2787
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 109.0 mmHg 0.89 2.0 intra-aortic thoracic radiotelemetry 0.0 0 103168 2787
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 142.0 mmHg 1.34 3.0 intra-aortic thoracic radiotelemetry 0.0 0 103169 2787
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 107.0 mmHg 1.34 3.0 intra-aortic thoracic radiotelemetry 0.0 0 103170 2787
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) then ambient air (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 101.0 mmHg 0.89 2.0 intra-aortic thoracic radiotelemetry 0.0 0 103174 2787
SR/Jr respiration rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (10 %) (for 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. respiratory function trait not specified 86 days 5 sampling once per minute 144.0 breaths/min 1.34 3.0 spirometry 0.0 0 103178 2787
SR/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) (between 0.5 and 0.6 hours) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 468.0 beats/min 1.79 4.0 intra-aortic thoracic radiotelemetry 0.0 0 103189 2787
SR/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) (between 0.5 and 0.6 hours) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 455.0 beats/min 4.47 10.0 intra-aortic thoracic radiotelemetry 0.0 5 min 103191 2787
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 112.0 mmHg 1.34 3.0 intra-aortic thoracic radiotelemetry 0.0 0 103199 2787
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 114.0 mmHg 2.24 5.0 intra-aortic thoracic radiotelemetry 0.0 0 103203 2787
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) then ambient air (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 114.0 mmHg 2.24 5.0 intra-aortic thoracic radiotelemetry 0.0 0 103207 2787
SS/JrHsd body weight controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 252.0 g 3.8 body weighing method 0.0 0 102189 2681
SR/JrHsd single kidney wet weight controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 1.05 g 0.03 post excision weight measurement 0.0 0 102196 2681
SR/JrHsd single kidney wet weight controlled sodium chloride content diet (4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 1.11 g 0.02 post excision weight measurement 0.0 0 102200 2681
SR/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female 0 days 0 122.0 mmHg 4.0 vascular fluid filled catheter 0.0 0 102207 2681
SR/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female 0 days 0 125.0 mmHg 2.0 vascular fluid filled catheter 0.0 0 102208 2681
SR/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 2.2 ml/min/g 0.31 inulin analysis by liquid phase colorimetry 0.0 0 102213 2681
SR/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 2.49 ml/min/g 0.2 inulin analysis by liquid phase colorimetry 0.0 0 102214 2681
SR/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 1.97 ml/min/g 0.25 inulin analysis by liquid phase colorimetry 0.0 0 102215 2681
SS/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 2.46 ml/min/g 0.06 inulin analysis by liquid phase colorimetry 0.0 0 102216 2681
SS/NEisSlc end-systolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 126 days 10 0.13 ml 0.02 0.07 volume pressure recording 0.0 0 102515 2690
SS/NEisSlc end-diastolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 126 days 10 0.24 ml 0.03 0.11 volume pressure recording 0.0 0 102519 2690
SR/NEisSlc heart left ventricle diastolic volume-axis intercept controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 77 days 10 0.08 ml 0.02 0.07 volume pressure recording 0.0 0 102532 2690
SS/NEisSlc heart left ventricle diastolic volume-axis intercept controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 126 days 10 0.08 ml 0.02 0.06 volume pressure recording 0.0 0 102535 2690
SS/NEisSlc time constant of left ventricular pressure decay controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 126 days 10 13.3 ms 0.79 2.5 volume pressure recording 0.0 0 102537 2690
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77 days 14 mean of 3 samples of undefined duration serial mean 173.0 mmHg 2.67 10.0 tail cuff plethysmography 0.0 0 102466 2689
SR/NEisSlc body weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. body mass male 77 days 10 356.0 g 3.48 11.0 body weighing method 0.0 0 102480 2690
SS/NEisSlc body weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. body mass male 77 days 10 344.0 g 8.22 26.0 body weighing method 0.0 0 102482 2690
SS/NEisSlc heart left ventricle weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 77 days 10 1.15 g 0.0 0.0 post excision weight measurement 0.0 0 102486 2690
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. arterial blood pressure trait male 126 days 10 undefined 135.0 mmHg 2.21 7.0 tail cuff plethysmography 0.0 0 102493 2690
SR/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 77 days 10 464.0 beats/min 8.54 27.0 tail cuff plethysmography 0.0 0 102496 2690
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 77 days 10 334.0 beats/min 13.28 42.0 tail cuff plethysmography 0.0 0 102506 2690
SR/NEisSlc left ventricular end-diastolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 2.2 mmHg 0.6 1.9 volume pressure recording 0.0 0 102508 2690
SS.BN-(D13Hmgc64-RN34_13048990782)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (8 %) (for 21 days) Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1. arterial blood pressure trait male 91 days 11 serial mean 173.0 mmHg 7.0 23.22 intra-aortic abdominal radiotelemetry via femoral cannulation 10800.0 0 98701 2141
SS mean arterial blood pressure controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. arterial blood pressure trait male 91 days 8 160.0 mmHg 4.6 13.0 tail cuff plethysmography 0.0 0 102268 2683
LH/MavRrrcAek mean arterial blood pressure standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. arterial blood pressure trait male 119 days 9 mean of 15 sec every 5 min for 72 hours serial mean 136.1 mmHg 1.7 5.1 intra-aortic abdominal radiotelemetry via femoral cannulation 0.0 0 102607 3014
LH/MavRrrcAek plasma total cholesterol level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 28 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood cholesterol amount male 126 days 9 81.47 mg/dl 5.41 16.22 plasma total cholesterol measurement test 0.0 0 102635 3014
SS/JrHsdMcwi heart rate controlled sodium chloride content diet (0.4 %) (between 23 and 32 days) then controlled sodium chloride content diet (8 %) (for 14 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. heart pumping trait male 58 days-67 days 14 serial mean 387.0 beats/min 6.0 22.45 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 carotid a. to thoracic aorta implant 98521 2079
SS-Agtrapem4Mcwi-/- single kidney wet weight controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. kidney mass male 60 days-69 days 0 1.37 g 0.05 digital scale post excision weight measurement 0.0 0 98456 2059
SS-Renem1Mcwi+/- systolic blood pressure controlled sodium chloride content diet (0.4 %) (between 66 and 69 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. arterial blood pressure trait male 66 days-69 days 9 serial mean 144.19 mmHg 2.22 6.66 intra-aortic abdominal radiotelemetry 32400.0 0 98376 2038
SS.BN-(D13Hmgc354-D13Rat32)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium chloride content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60 days-67 days 15 serial mean 134.0 mmHg 4.0 15.49 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 intra-carotid radiotelemetry strain 26-J 98562 2098
SR/Jr single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. kidney mass male 63 days 13 8.13 g/kg 0.15 0.54 post excision weight measurement 0.0 0 103243 2802
SS/Jr single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. kidney mass male 63 days 10 8.65 g/kg 0.17 0.54 post excision weight measurement 0.0 0 103245 2802
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 16 113.0 mmHg 2.0 8.0 vascular transducer tipped catheter 0.0 0 103250 2802
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 15 131.0 mmHg 3.0 11.62 vascular transducer tipped catheter 0.0 0 103252 2802
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 10 153.0 mmHg 7.0 22.14 vascular transducer tipped catheter 0.0 0 103253 2802
SR/Jr diastolic blood pressure controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 16 91.0 mmHg 3.0 12.0 vascular transducer tipped catheter 0.0 0 103254 2802
SS/Jr plasma triglyceride level controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. blood triglyceride amount male 63 days 15 1.2 mmol/l 0.16 0.62 plasma triglyceride analysis 0.0 0 103260 2802
SS/Jr plasma triglyceride level controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. blood triglyceride amount male 63 days 10 1.49 mmol/l 0.29 0.92 plasma triglyceride analysis 0.0 0 103261 2802
SS-Renem1Mcwi+/+ serum bicarbonate level controlled sodium chloride content diet (0.4 %) (for 42 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. blood bicarbonate amount male 63 days 5 27.6 mmol/l 0.58 1.3 automated serum bicarbonate test 0.0 0 98367 2038
SR/Hsd creatinine clearance controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. glomerular filtration trait male 91 days 8 6.1 ml/min 0.28 0.8 urine creatinine analysis 0.0 0 102289 2683
SS/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 63 days 8 292.0 g 3.18 9.0 body weighing method 0.0 0 102406 2689
SS/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 70 days 7 297.0 g 5.29 14.0 body weighing method 0.0 0 102408 2689
SR/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 77 days 7 371.0 g 4.54 12.0 body weighing method 0.0 0 102409 2689
SS/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 70 days 7 373.0 beats/min 3.78 10.0 tail cuff plethysmography 0.0 0 102414 2689
SR/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 77 days 7 3.67 g/kg 0.05 0.13 post excision weight measurement 0.0 0 102427 2689
SS/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 63 days 8 2.4 mEq/d 0.25 0.7 automated urine sodium analysis 0.0 0 102436 2689
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 70 days 8 1.9 mEq/d 0.21 0.6 automated urine sodium analysis 0.0 0 102437 2689
SR/NEisSlc kidney cortical adrenomedullin level controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 63 days 7 0.59 fmol/mg 0.04 0.1 radioimmunoassay 0.0 0 102441 2689
SR/NEisSlc kidney cortical adrenomedullin level controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 77 days 7 0.55 fmol/mg 0.02 0.06 radioimmunoassay 0.0 0 102445 2689
SR/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 77 days 19 3.4 mg/d/100 g 0.21 0.9 urine protein analysis 0.0 0 102477 2689
SS/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) then adrenomedulin (400 ng/hr) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 77 days 14 5.7 mg/d/100 g 0.43 1.6 urine protein analysis 0.0 0 102479 2689
SS-Renem1Mcwi+/- urine creatinine excretion rate controlled sodium chloride content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine creatinine amount female 56 days 9 5.4 mg/d 0.18 0.54 urine creatinine analysis 0.0 0 98335 2038
SS-Plekha7em4Mcwi+/+ nephron count controlled sodium chloride content diet (8 %) (for 28 days) Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18. nephron morphology trait male 91 days 10 33450.0 null 208.0 657.75 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 nephron count 105751 3022
LN/MavRrrcAek plasma leptin level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 28 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood leptin amount male 126 days 11 0.35 ng/ml 0.03 0.16 plasma leptin analysis 0.0 0 automated plasma leptin analysis 105320 3014
LH/MavRrrcAek maximum slope of body weight growth curve standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. body mass male 21 days-126 days 0 y=mx + c 45.1 g/week 0.74 body weighing method 0.0 0 maximum slope of body weight growth curve (CMO:0003452) 107402 3014
SR/Jr maximum rate of positive change in left ventricular blood pressure to left ventricular systolic blood pressure ratio controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then pentobarbital, sodium (20 mg/kg) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart left ventricular blood pressure trait not specified 84 days 5 LVdP/dtmax/P 72.0 /s 4.02 1.0 vascular transducer tipped catheter 0.0 0 106816 2787
SS-Chr 13BN/McwiCrl mean arterial blood pressure controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77 days-98 days 4 MAP=.33(SP-DP) + DP 106.0 mmHg 4.0 8.0 vascular fluid filled catheter femoral artery 600.0 0 106759 2685
SS-Chr 13BN/McwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77 days-98 days 4 MAP=.33(SP-DP) + DP 110.0 mmHg 2.0 4.0 vascular fluid filled catheter femoral artery 600.0 0 106761 2685
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) then 2% dimethyl sulfoxide in artificial cerebrospinal fluid (300 nl/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77 days-98 days 4 MAP=.33(SP-DP) + DP 150.0 mmHg 8.0 16.0 vascular fluid filled catheter femoral artery 600.0 0 106762 2685
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77 days-98 days 5 MAP=.33(SP-DP) + DP 149.0 mmHg 3.0 6.71 vascular fluid filled catheter femoral artery 600.0 0 106768 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77 days-98 days 4 435.0 beats/min 12.0 24.0 vascular fluid filled catheter femoral artery 600.0 0 106771 2685
SBH/Ygl blood glucose level controlled sodium chloride content diet (8 %) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. blood glucose amount male 98 days 7 109.8 mg/dl 3.6 9.52 blood glucose test strip read by electrochemical glucometer 0.0 0 106693 3038
SS-Shc1em4Mcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 5 21.7 um 0.8 1.79 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106497 3030
SS-Chr 2BN/Mcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 6 20.8 um 1.0 2.45 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106500 3030
SS/JrHsdMcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 10 24.6 um 0.8 2.53 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106504 3030
SS-Shc1em4Mcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 7 23.9 um 1.6 4.23 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106506 3030
SS/JrHsdMcwi spleen weight controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. spleen mass not specified 63 days 4 1.5 g 0.1 0.2 post excision weight measurement 0.0 0 n=4-7 106508 3031
SS-Sh2b3em1Mcwi-/- spleen weight controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. spleen mass not specified 63 days 4 2.4 g 0.2 0.4 post excision weight measurement 0.0 0 n=4-7 106509 3031
SS/JrHsdMcwi blood mononuclear cell count controlled sodium chloride content diet (0.4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. leukocyte quantity not specified 84 days 4 5.9 x 10E6 cells/ml 0.9 1.8 flow cytometry method 0.0 0 n=4-7 106510 3031
SS/JrHsdMcwi blood B lymphocyte count controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. B cell quantity not specified 63 days 4 1.0 x 10E6 cells/ml 0.2 0.4 flow cytometry method 0.0 0 n=4-7 106514 3031
SS-Sh2b3em1Mcwi-/- blood B lymphocyte count controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. B cell quantity not specified 63 days 4 4.0 x 10E6 cells/ml 0.3 0.6 flow cytometry method 0.0 0 n=4-7 106515 3031
SS/JrHsdMcwi blood regulatory T cell count to total T cell count ratio controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. T cell quantity not specified 63 days 4 4.0 % 0.1 0.2 flow cytometry method 0.0 0 n=4-7 -tregs spleen % 106518 3031
SS/JrHsdMcwi urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (for 42 days) then controlled sodium chloride content diet (4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. urine albumin amount not specified 84 days 6 104.9 mg/d 8.9 21.8 urine albumin analysis 0.0 0 n=6-8 106528 3031
SS/JrHsdMcwi kidney total CD3 positive T cell count controlled sodium chloride content diet (0.4 %) (for 84 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. T cell quantity not specified 84 days 5 0.21 x 10E6 cells/ml 0.03 0.07 flow cytometry method 0.0 0 n=5-6 (tissue T cell count) 106533 3031
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77 days-98 days 4 MAP=.33(SP-DP) + DP 109.0 mmHg 3.0 6.0 vascular fluid filled catheter femoral artery 600.0 0 106756 2685
SBH/Ygl body weight controlled sodium chloride content diet (0.65 %) (for 98 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. body mass male 98 days 7 223.0 g 15.0 39.69 body weighing method 0.0 0 106702 3038
SBH/Ygl food intake weight to body weight ratio controlled sodium chloride content diet (0.65 %) (for 84 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 28 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. eating behavior trait male 84 days 7 18.04 g/d/100g 0.82 2.17 food intake measuring method 0.0 0 106706 3038
SBH/Ygl heart left ventricle end-systolic diameter to body weight ratio controlled sodium chloride content diet (8 %) (for 42 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart left ventricle end-systolic diameter male 98 days 7 0.95 mm/kg 0.09 0.24 transthoracic echocardiography 0.0 0 106723 3038
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77 days-98 days 4 444.0 beats/min 7.0 14.0 vascular fluid filled catheter femoral artery 600.0 0 106774 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77 days-98 days 5 444.0 beats/min 16.0 35.78 vascular fluid filled catheter femoral artery 600.0 0 106777 2685
SS/Jr ouabain-sensitive red blood cell Na+ export rate controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 10 5475.0 umol/l/h 442.0 1397.73 Na+/K+ ATPase activity assay 0.0 0 111036 2802
SS/Jr bumetanide-sensitive red blood cell Na+ export rate controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 10 614.0 umol/l/h 160.0 505.96 Na-K-Cl cotransport activity assay 0.0 0 111040 2802
SR/Jr ouabain- and bumetanide-resistant red blood cell Na+ import rate controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 16 3586.0 umol/l/h 110.0 440.0 Na+ passive permeability assay 0.0 0 111041 2802
SS/Jr bumetanide-sensitive red blood cell K+ import rate controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 15 775.0 umol/l/h 65.0 251.74 Na-K-Cl cotransport activity assay 0.0 0 111051 2802
SR/Jr ouabain- and bumetanide-resistant red blood cell K+ import rate controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 13 408.0 umol/l/h 14.0 50.48 Na+ passive permeability assay 0.0 0 111054 2802
SS/Jr ouabain- and bumetanide-resistant red blood cell K+ import rate controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 15 424.0 umol/l/h 14.0 54.22 Na+ passive permeability assay 0.0 0 111055 2802
LEW/Mol body weight controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. body mass female 104 days 8 195.0 g 1.7 4.81 body weighing method 0.0 0 108998 3134
LEW/Mol body weight controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. body mass male 104 days 8 287.0 g 3.6 10.18 body weighing method 0.0 0 108999 3134
MWF/Fub body weight controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. body mass female 104 days 8 188.0 g 1.6 4.53 body weighing method 0.0 0 109002 3134
MWF/Fub kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. kidney mass male 104 days 8 3.49 mg/g 0.1 0.28 post excision weight measurement kidney 0.0 0 109019 3134
MWF/Fub systolic blood pressure controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. arterial blood pressure trait male 100 days-103 days 8 133.0 mmHg 3.0 8.49 tail cuff plethysmography tail 0.0 0 109023 3134
BN.GH-(D2Rat22-D2Mgh11)(D6Mit12-D6Rat15)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 3 days) then controlled sodium chloride content diet (4 %) (for 23 days) Bilusic M, et al., Croat Med J. 2008 Oct;49(5):586-99. arterial blood pressure trait male 155 days-169 days 16 serial mean 98.1 mmHg 1.98 7.9 radiotelemetry left femoral artery 10 seconds every two minutes for 4 hrs/day every other day for 23 days 0 Dataquest IV system; anesthetized by 1% isoflurane, recover for 3 days 11557 101
BN.GH-(D6Mit12-D6Rat15)(D18Rat41-D18Mgh4)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 3 days) then controlled sodium chloride content diet (4 %) (for 23 days) Bilusic M, et al., Croat Med J. 2008 Oct;49(5):586-99. arterial blood pressure trait male 155 days-169 days 16 serial mean 99.5 mmHg 2.6 10.4 radiotelemetry left femoral artery 10 seconds every two minutes for 4 hrs/day every other day for 23 days 0 Dataquest IV system; anesthetized by 1% isoflurane, recover for 3 days 11558 101
SS.BN-(D13Hmgc1048-D13Hmgc664)/Mcwi systolic blood pressure controlled sodium chloride content diet (0.4 %) (between 23 and 32 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 44 days-53 days 15 serial mean 117.0 mmHg 2.0 7.75 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 carotid a. to thoracic aorta implant strain 26-N 98480 2079
SR/Jr heart weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart mass not specified 84 days 5 3.22 g/kg 0.12 0.27 post excision weight measurement 0.0 0 103146 2787
SR/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 341.0 beats/min 1.79 4.0 intra-aortic thoracic radiotelemetry 0.0 0 103156 2787
SS/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 343.0 beats/min 5.81 13.0 intra-aortic thoracic radiotelemetry 0.0 0 103157 2787
SR/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 314.0 beats/min 5.37 12.0 intra-aortic thoracic radiotelemetry 0.0 0 103158 2787
SS/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (for 0.4 hours) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 479.0 beats/min 10.73 24.0 intra-aortic thoracic radiotelemetry 0.0 5 min 103161 2787
SR/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (for 0.4 hours) then ambient air (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 356.0 beats/min 10.73 24.0 intra-aortic thoracic radiotelemetry 0.0 25 min 103164 2787
SS/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) (between 0.5 and 0.6 hours) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 4 sampling once per minute 455.0 beats/min 2.5 5.0 intra-aortic thoracic radiotelemetry 0.0 0 103188 2787
SS/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) (between 0.5 and 0.6 hours) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 4 sampling once per minute 438.0 beats/min 7.0 14.0 intra-aortic thoracic radiotelemetry 0.0 5 min 103190 2787
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 4 sampling once per minute 135.0 mmHg 2.0 4.0 intra-aortic thoracic radiotelemetry 0.0 0 103204 2787
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) then ambient air (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 4 sampling once per minute 131.0 mmHg 2.0 4.0 intra-aortic thoracic radiotelemetry 0.0 0 103206 2787
SR/JrHsd body weight controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 200.0 g 2.5 body weighing method 0.0 0 102187 2681
SR/JrHsd body weight controlled sodium chloride content diet (4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 213.0 g 2.2 body weighing method 0.0 0 102188 2681
SS/JrHsd body weight controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 294.0 g 4.0 body weighing method 0.0 0 102191 2681
SS/JrHsd body weight controlled sodium chloride content diet (4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 228.0 g 6.1 body weighing method 0.0 0 102194 2681
SR/JrHsd single kidney wet weight controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 0.86 g 0.02 post excision weight measurement 0.0 0 102195 2681
SS/JrHsd single kidney wet weight controlled sodium chloride content diet (4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 1.71 g 0.08 post excision weight measurement 0.0 0 102206 2681
SR/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female 0 days 0 112.0 mmHg 5.0 vascular fluid filled catheter 0.0 0 102209 2681
SS/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 1.96 ml/min/g 0.04 inulin analysis by liquid phase colorimetry 0.0 0 102218 2681
SS/NEisSlc left ventricular end-diastolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 126 days 10 6.3 mmHg 1.14 3.6 volume pressure recording 0.0 0 102511 2690
SR/NEisSlc end-systolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 77 days 10 0.07 ml 0.02 0.06 volume pressure recording 0.0 0 102512 2690
SS/NEisSlc time constant of left ventricular pressure decay controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 15.8 ms 1.68 5.3 volume pressure recording 0.0 0 102538 2690
SS/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 21 days) then adrenomedulin (400 ng/hr) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 77 days 14 350.0 g 3.74 14.0 body weighing method 0.0 0 102455 2689
SS/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 77 days 14 4.63 g/kg 0.07 0.26 post excision weight measurement 0.0 0 102463 2689
SS/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) then adrenomedulin (400 ng/hr) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77 days 14 1.7 mEq/d 0.13 0.5 automated urine sodium analysis 0.0 0 102470 2689
SR/NEisSlc heart left ventricle weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 126 days 10 1.95 mg/g 0.03 0.09 post excision weight measurement 0.0 0 102489 2690
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. arterial blood pressure trait male 77 days 10 undefined 140.0 mmHg 2.21 7.0 tail cuff plethysmography 0.0 0 102492 2690
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. arterial blood pressure trait male 126 days 10 undefined 249.0 mmHg 5.06 16.0 tail cuff plethysmography 0.0 0 102495 2690
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 77 days 10 518.0 beats/min 3.48 11.0 tail cuff plethysmography 0.0 0 102498 2690
SS/NEisSlc left ventricular systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 126 days 10 148.0 mmHg 6.96 22.0 volume pressure recording 0.0 0 102503 2690
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 126 days 10 383.0 beats/min 15.18 48.0 tail cuff plethysmography 0.0 0 102505 2690
LN/MavRrrcAek systolic blood pressure standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. arterial blood pressure trait male 119 days 14 mean of 15 sec every 5 min for 72 hours serial mean 116.0 mmHg 1.4 5.24 intra-aortic abdominal radiotelemetry via femoral cannulation 0.0 0 102610 3014
LN/MavRrrcAek diastolic blood pressure standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. arterial blood pressure trait male 119 days 14 mean of 15 sec every 5 min for 72 hours serial mean 86.1 mmHg 1.1 4.12 intra-aortic abdominal radiotelemetry via femoral cannulation 0.0 0 102612 3014
LH/MavRrrcAek heart rate standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. heart pumping trait male 119 days 9 319.2 beats/min 1.8 5.4 intra-aortic abdominal radiotelemetry via femoral cannulation 0.0 0 102615 3014
LH/MavRrrcAek plasma triglyceride level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 14 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood triglyceride amount male 112 days 9 0.43 mmol/l 0.05 0.15 plasma triglyceride analysis 0.0 0 102627 3014
SS.BN-(D13Hmgc115-D13Got22)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 68 days) then controlled sodium chloride content diet (8 %) (for 21 days) Moreno C, et al., Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1530-5. doi: 10.1152/ajpheart.01026.2010. Epub 2011 Jan 21. arterial blood pressure trait male 89 days 12 serial mean 156.0 mmHg 4.0 13.86 intra-aortic abdominal radiotelemetry via femoral cannulation 10800.0 0 strain 5-2 98675 2138
SS/Hsd urine sodium excretion rate controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine sodium amount male 60 days-69 days 0 10.0 mEq/d 0.6 urine electrolyte analysis 0.0 0 98450 2059
SR/Jr systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 16 137.0 mmHg 3.0 12.0 vascular transducer tipped catheter 0.0 0 103246 2802
SS/Jr diastolic blood pressure controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 10 124.0 mmHg 6.0 18.97 vascular transducer tipped catheter 0.0 0 103257 2802
SR/Jr plasma triglyceride level controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. blood triglyceride amount male 63 days 16 0.43 mmol/l 0.11 0.44 plasma triglyceride analysis 0.0 0 103258 2802
SR/Jr hematocrit controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte quantity male 63 days 13 43.5 % 0.5 1.8 hematocrit analysis 0.0 0 103267 2802
SS-Renem1Mcwi-/- serum alanine aminotransferase activity level controlled sodium chloride content diet (0.4 %) (for 42 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. blood alanine transaminase amount male 63 days 8 53.63 U/l 5.74 16.24 automated serum analysis 0.0 0 98357 2038
SR/Hsd urine sodium level controlled sodium chloride content diet (8 %) (for 28 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. urine sodium amount male 77 days 8 3.8 mmol/l 0.21 0.6 urine sodium analysis 0.0 0 102283 2683
SR/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 63 days 7 286.0 g 6.05 16.0 body weighing method 0.0 0 102405 2689
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 70 days 8 396.0 beats/min 12.73 36.0 tail cuff plethysmography 0.0 0 102413 2689
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 63 days 8 mean of 3 samples of undefined duration serial mean 126.0 mmHg 2.12 6.0 tail cuff plethysmography 0.0 0 102430 2689
SS/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 70 days 7 1.9 mEq/d 0.34 0.9 automated urine sodium analysis 0.0 0 102438 2689
SS/NEisSlc kidney cortical adrenomedullin level controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 77 days 8 0.74 fmol/mg 0.02 0.06 radioimmunoassay 0.0 0 102446 2689
SR/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 7 days) then 0.9% sodium chloride solution (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 63 days 19 3.4 mg/d/100 g 0.25 1.1 urine protein analysis 0.0 0 102471 2689
SS-Renem1Mcwi-/- mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 66 and 69 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. arterial blood pressure trait male 66 days-69 days 8 serial mean 58.36 mmHg 2.38 6.73 intra-aortic abdominal radiotelemetry 32400.0 0 98380 2038
SS-Shc1em5Mcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 8 24.5 um 1.5 4.24 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106507 3030
SS-Sh2b3em1Mcwi-/- blood mononuclear cell count controlled sodium chloride content diet (0.4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. leukocyte quantity not specified 84 days 4 14.7 x 10E6 cells/ml 0.6 1.2 flow cytometry method 0.0 0 n=4-7 106511 3031
SS-Sh2b3em1Mcwi-/- mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 70 days 6 15sec/min for 3 hrs/day for 7days 127.7 mmHg 2.0 4.9 vascular fluid filled catheter 0.0 0 n=6-8 106521 3031
SS/JrHsdMcwi urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (for 42 days) then controlled sodium chloride content diet (4 %) (for 10 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. urine albumin amount not specified 73 days 6 101.1 mg/d 15.4 37.72 urine albumin analysis 0.0 0 n=6-8 106526 3031
SS-Sh2b3em1Mcwi-/- urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (for 42 days) then controlled sodium chloride content diet (4 %) (for 10 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. urine albumin amount not specified 73 days 6 9.4 mg/d 2.4 5.88 urine albumin analysis 0.0 0 n=6-8 106527 3031
SS/JrHsdMcwi kidney total CD45 positive leukocyte count controlled sodium chloride content diet (0.4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. leukocyte quantity not specified 84 days 5 2.13 x 10E6 cells/ml 0.36 0.8 flow cytometry method 0.0 0 n=5-6 106531 3031
SBH/Ygl systolic blood pressure controlled sodium chloride content diet (0.65 %) (for 98 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. arterial blood pressure trait male 98 days 7 139.0 mmHg 1.0 2.65 tail cuff plethysmography 0.0 0 106696 3038
SBH/Ygl systolic blood pressure controlled sodium chloride content diet (0.65 %) (for 98 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. arterial blood pressure trait male 98 days 7 128.0 mmHg 2.0 5.29 tail cuff plethysmography 0.0 0 106698 3038
SBH/Ygl systolic blood pressure controlled sodium chloride content diet (8 %) (for 42 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. arterial blood pressure trait male 98 days 7 181.0 mmHg 2.0 5.29 tail cuff plethysmography 0.0 0 106699 3038
SBH/Ygl food intake weight to body weight ratio controlled sodium chloride content diet (0.65 %) (for 84 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. eating behavior trait male 84 days 7 9.47 g/d/100g 0.69 1.83 food intake measuring method 0.0 0 106704 3038
SBH/Ygl heart left ventricle end-diastolic diameter to body weight ratio controlled sodium chloride content diet (8 %) (for 42 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart left ventricle end-diastolic diameter male 98 days 7 2.7 mm/kg 0.1 0.26 transthoracic echocardiography 0.0 0 106719 3038
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) then 2% dimethyl sulfoxide in artificial cerebrospinal fluid (300 nl/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77 days-98 days 4 442.0 beats/min 5.0 10.0 vascular fluid filled catheter femoral artery 600.0 0 106778 2685
SS-Chr 13BN/McwiCrl heart rate controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77 days-98 days 4 409.0 beats/min 7.0 14.0 vascular fluid filled catheter femoral artery 600.0 0 106780 2685
SS-Chr 13BN/McwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77 days-98 days 5 MAP=.33(SP-DP) + DP 112.0 mmHg 3.0 6.71 vascular fluid filled catheter femoral artery 600.0 0 106760 2685
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) then 2% dimethyl sulfoxide in artificial cerebrospinal fluid (300 nl/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77 days-98 days 5 MAP=.33(SP-DP) + DP 110.0 mmHg 2.0 4.47 vascular fluid filled catheter femoral artery 600.0 0 106764 2685
SHRSP/A3NCrl urine sodium excretion rate controlled sodium chloride content diet (1 %) (for 56 days) and controlled fat content diet (24.5 %) (for 56 days) Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. urine sodium amount male 84 days-91 days 9 2.4 mEq/d 0.4 1.2 urine sodium analysis 86400.0 0 baseline baseline high salt high fat diet group 107063 3073
SS/Jr ouabain- and bumetanide-resistant red blood cell Na+ import rate controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 15 3803.0 umol/l/h 134.0 518.98 Na+ passive permeability assay 0.0 0 111043 2802
SR/Jr ouabain-sensitive red blood cell K+ import rate controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 16 4275.0 umol/l/h 135.0 540.0 Na+/K+ ATPase activity assay 0.0 0 111045 2802
SS/Jr ouabain- and bumetanide-resistant red blood cell K+ import rate controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 10 499.0 umol/l/h 33.0 104.36 Na+ passive permeability assay 0.0 0 111056 2802
LEW/Mol kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. kidney mass male 104 days 8 4.33 mg/g 0.09 0.25 post excision weight measurement kidney 0.0 0 109015 3134
MWF/Fub kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. kidney mass female 104 days 8 3.69 mg/g 0.07 0.2 post excision weight measurement kidney 0.0 0 109018 3134
SR/Jr left ventricular systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then pentobarbital, sodium (20 mg/kg) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart left ventricular blood pressure trait not specified 84 days 5 119.0 mmHg 4.02 9.0 vascular transducer tipped catheter 0.0 0 103150 2787
SS/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (for 0.4 hours) then ambient air (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 428.0 beats/min 10.73 24.0 intra-aortic thoracic radiotelemetry 0.0 25 min 103163 2787
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 135.0 mmHg 0.89 2.0 intra-aortic thoracic radiotelemetry 0.0 0 103165 2787
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 144.0 mmHg 1.34 3.0 intra-aortic thoracic radiotelemetry 0.0 0 103167 2787
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 142.0 mmHg 2.24 5.0 intra-aortic thoracic radiotelemetry 0.0 0 103171 2787
SR/Jr respiration rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. respiratory function trait not specified 86 days 5 sampling once per minute 120.0 breaths/min 1.79 4.0 spirometry 0.0 0 103176 2787
SS/Jr respiration rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (10 %) (for 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. respiratory function trait not specified 86 days 5 sampling once per minute 145.0 breaths/min 1.34 3.0 spirometry 0.0 0 103177 2787
SS/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) (between 0.9 and 1 hours) then 10% CO2, 20% O2, 70% N2 (for 0.4 hours) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 4 sampling once per minute 486.0 beats/min 4.5 9.0 intra-aortic thoracic radiotelemetry 0.0 25 min 103194 2787
SR/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) (between 0.9 and 1 hours) then 10% CO2, 20% O2, 70% N2 (for 0.4 hours) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 472.0 beats/min 4.47 10.0 intra-aortic thoracic radiotelemetry 0.0 25 min 103195 2787
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 117.0 mmHg 1.34 3.0 intra-aortic thoracic radiotelemetry 0.0 0 103201 2787
SS/NEisSlc end-systolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 77 days 10 0.03 ml 0.0 0.01 volume pressure recording 0.0 0 102514 2690
SR/NEisSlc heart left ventricle end-systolic elastance controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 2404.0 mmHg/ml 78.42 248.0 volume pressure recording 0.0 0 102520 2690
SR/NEisSlc time constant of left ventricular pressure decay controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 107.0 ms 0.79 2.5 volume pressure recording 0.0 0 102536 2690
SR/JrHsd body weight controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 232.0 g 4.1 body weighing method 0.0 0 102184 2681
SS/JrHsd body weight controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 235.0 g 13.0 body weighing method 0.0 0 102190 2681
SS/JrHsd body weight controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 211.0 g 4.6 body weighing method 0.0 0 102193 2681
SR/JrHsd single kidney wet weight controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 0.88 g 0.02 post excision weight measurement 0.0 0 102199 2681
SS/JrHsd single kidney wet weight controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 0.87 g 0.02 post excision weight measurement 0.0 0 102201 2681
SS/JrHsd single kidney wet weight controlled sodium chloride content diet (4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 1.37 g 0.03 post excision weight measurement 0.0 0 102204 2681
SS/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female 0 days 0 129.0 mmHg 5.0 vascular fluid filled catheter 0.0 0 102210 2681
SS-Plod1em1Mcwi-/- systolic blood pressure controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 10 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. arterial blood pressure trait male 58 days-67 days 0 serial mean 165.0 mmHg 4.0 intra-aortic abdominal radiotelemetry 32400.0 0 98411 2059
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77 days 19 347.0 beats/min 7.34 32.0 tail cuff plethysmography 0.0 0 102456 2689
SS/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77 days 14 355.0 beats/min 10.16 38.0 tail cuff plethysmography 0.0 0 102457 2689
SR/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 77 days 19 3.85 g/kg 0.06 0.28 post excision weight measurement 0.0 0 102462 2689
SS/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) then adrenomedulin (400 ng/hr) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 77 days 14 4.52 g/kg 0.07 0.27 post excision weight measurement 0.0 0 102464 2689
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77 days 19 mean of 3 samples of undefined duration serial mean 128.0 mmHg 1.38 6.0 tail cuff plethysmography 0.0 0 102465 2689
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) then adrenomedulin (9.6 ug/d) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77 days 14 mean of 3 samples of undefined duration serial mean 150.0 mmHg 2.67 10.0 tail cuff plethysmography 0.0 0 102467 2689
SS/NEisSlc heart left ventricle weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 126 days 10 4.39 mg/g 0.08 0.24 post excision weight measurement 0.0 0 102491 2690
SR/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 77 days 10 383.0 beats/min 6.96 22.0 tail cuff plethysmography 0.0 0 102504 2690
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 126 days 10 326.0 beats/min 13.28 42.0 tail cuff plethysmography 0.0 0 102507 2690
SS/JrHsdMcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (8 %) (for 21 days) Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1. arterial blood pressure trait female 91 days 13 serial mean 174.0 mmHg 5.0 18.03 intra-aortic abdominal radiotelemetry via femoral cannulation 10800.0 0 98700 2141
SS/Jr tibia midshaft endosteal cross-sectional area controlled sodium chloride content diet (2 %) (between 38 and 42 days) Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. tibia morphology trait male 66 days-70 days 0 3.02 mm2 0.09 micro-computed tomography 0.0 0 98013 1958
SS-Plod1em1Mcwi-/- mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 10 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. arterial blood pressure trait male 58 days-67 days 0 serial mean 143.0 mmHg 3.0 intra-aortic abdominal radiotelemetry 32400.0 0 98397 2059
SS-Mthfrem1Mcwi-/+ mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 10 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. arterial blood pressure trait male 58 days-67 days 0 serial mean 130.0 mmHg 4.0 intra-aortic abdominal radiotelemetry 32400.0 0 98401 2059
LN/MavRrrcAek mean arterial blood pressure standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. arterial blood pressure trait male 119 days 14 mean of 15 sec every 5 min for 72 hours serial mean 99.9 mmHg 1.2 4.49 intra-aortic abdominal radiotelemetry via femoral cannulation 0.0 0 102608 3014
LH/MavRrrcAek systolic blood pressure standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. arterial blood pressure trait male 119 days 9 mean of 15 sec every 5 min for 72 hours serial mean 161.2 mmHg 2.1 6.3 intra-aortic abdominal radiotelemetry via femoral cannulation 0.0 0 102609 3014
LH/MavRrrcAek diastolic blood pressure standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. arterial blood pressure trait male 119 days 9 mean of 15 sec every 5 min for 72 hours serial mean 113.9 mmHg 1.6 4.8 intra-aortic abdominal radiotelemetry via femoral cannulation 0.0 0 102611 3014
LH/MavRrrcAek plasma glucose level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 14 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood glucose amount male 112 days 9 141.9 mg/dl 8.1 24.3 plasma glucose analysis 0.0 0 102623 3014
LH/MavRrrcAek plasma triglyceride level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 28 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood triglyceride amount male 126 days 9 0.91 mmol/l 0.07 0.21 plasma triglyceride analysis 0.0 0 102629 3014
SS.BN-(D13Rat25-RN34_13048990782)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (8 %) (for 21 days) Flister MJ, et al., Hypertension. 2013 Apr;61(4):850-6. doi: 10.1161/HYPERTENSIONAHA.111.01008. Epub 2013 Mar 4. arterial blood pressure trait male 91 days 21 serial mean 169.0 mmHg 6.0 27.5 intra-aortic abdominal radiotelemetry via femoral cannulation 10800.0 0 strain 9C 98723 2142
LN/MavRrrcAek plasma total cholesterol level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 28 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood cholesterol amount male 126 days 14 71.81 mg/dl 6.56 24.56 plasma total cholesterol measurement test 0.0 0 102636 3014
SS/Jr body weight controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. body mass male 63 days 10 201.0 g 20.0 63.25 body weighing method 0.0 0 103237 2802
SS-Renem1Mcwi+/+ diastolic blood pressure controlled sodium chloride content diet (0.4 %) (between 66 and 69 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. arterial blood pressure trait male 66 days-69 days 5 serial mean 101.76 mmHg 2.81 6.28 intra-aortic abdominal radiotelemetry 32400.0 0 98375 2038
SS-Renem1Mcwi-/- heart rate controlled sodium chloride content diet (0.4 %) (between 66 and 69 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. heart pumping trait male 66 days-69 days 8 serial mean 402.94 beats/min 4.46 12.61 intra-aortic abdominal radiotelemetry 32400.0 0 98393 2038
SS-Nppbem2Mcwi-/- heart left ventricle weight controlled sodium chloride content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle mass male 98 days 4 1.53 g 0.09 0.18 echocardiography 0.0 0 99727 2319
SS-Nppbem2Mcwi-/- heart rate controlled sodium chloride content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 98 days 4 421.0 beats/min 4.0 8.0 echocardiography 0.0 0 99729 2319
SS-Nppbem2Mcwi-/- single kidney wet weight controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. kidney mass male 60 days-69 days 0 1.45 g 0.02 digital scale post excision weight measurement 0.0 0 98452 2059
SR/Hsd urine sodium level controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. urine sodium amount male 91 days 8 3.1 mmol/l 0.07 0.2 urine sodium analysis 0.0 0 102285 2683
SS/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 63 days 8 398.0 beats/min 13.08 37.0 tail cuff plethysmography 0.0 0 102412 2689
SS/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77 days 8 399.0 beats/min 8.84 25.0 tail cuff plethysmography 0.0 0 102416 2689
SS/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 63 days 8 3.91 g/kg 0.05 0.14 post excision weight measurement 0.0 0 102424 2689
SS/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 70 days 7 4.46 g/kg 0.08 0.2 post excision weight measurement 0.0 0 102426 2689
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 70 days 7 mean of 3 samples of undefined duration serial mean 166.0 mmHg 1.89 5.0 tail cuff plethysmography 0.0 0 102432 2689
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 63 days 7 2.1 mEq/d 0.38 1.0 automated urine sodium analysis 0.0 0 102435 2689
SR/NEisSlc kidney medullary adrenomedullin level controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 70 days 8 0.34 fmol/mg 0.01 0.04 radioimmunoassay 0.0 0 102449 2689
SS/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 14 days) then 0.9% sodium chloride solution (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 70 days 14 6.5 mg/d/100 g 0.67 2.5 urine protein analysis 0.0 0 102475 2689
SS/Jr single kidney wet weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. kidney mass male 63 days 15 6.39 g/kg 0.13 0.5 post excision weight measurement 0.0 0 103244 2802
SS/Jr systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 15 159.0 mmHg 3.0 11.62 vascular transducer tipped catheter 0.0 0 103248 2802
SS/Jr diastolic blood pressure controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 15 108.0 mmHg 3.0 11.62 vascular transducer tipped catheter 0.0 0 103256 2802
SS-Renem1Mcwi+/- serum bicarbonate level controlled sodium chloride content diet (0.4 %) (for 42 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. blood bicarbonate amount male 63 days 9 27.67 mmol/l 0.5 1.5 automated serum bicarbonate test 0.0 0 98368 2038
SS.BN-(D13Got42-D13Got45)/Mcwi diastolic blood pressure controlled sodium chloride content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium chloride content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60 days-67 days 13 serial mean 153.0 mmHg 7.0 25.24 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 intra-carotid radiotelemetry strain 26-B 98583 2098
SS-Plekha7em4Mcwi-/- nephron count controlled sodium chloride content diet (8 %) (for 28 days) Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18. nephron morphology trait male 91 days 10 34330.0 null 480.0 1517.89 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 nephron count 105750 3022
SS/Jr minimum rate of positive change in left ventricular blood pressure controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then pentobarbital, sodium (20 mg/kg) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart left ventricular blood pressure trait not specified 84 days 5 LVdP/dtmin 7.6 10E3 mmHg/s 4.47 1.3 vascular transducer tipped catheter 0.0 0 minimum rate of positive change in left ventricular blood pressure 106817 2787
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77 days-98 days 4 MAP=.33(SP-DP) + DP 111.0 mmHg 4.0 8.0 vascular fluid filled catheter femoral artery 600.0 0 106765 2685
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77 days-98 days 5 MAP=.33(SP-DP) + DP 135.0 mmHg 4.0 8.94 vascular fluid filled catheter femoral artery 600.0 0 106766 2685
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77 days-98 days 4 MAP=.33(SP-DP) + DP 109.0 mmHg 2.0 4.0 vascular fluid filled catheter femoral artery 600.0 0 106767 2685
SBH/Ygl blood glucose level controlled sodium chloride content diet (0.65 %) (for 98 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. blood glucose amount male 98 days 7 383.4 mg/dl 21.6 57.15 blood glucose test strip read by electrochemical glucometer 0.0 0 106694 3038
SBH/Ygl blood glucose level controlled sodium chloride content diet (8 %) (for 42 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. blood glucose amount male 98 days 7 361.8 mg/dl 32.4 85.72 blood glucose test strip read by electrochemical glucometer 0.0 0 106695 3038
LH/MavRrrcAek plasma leptin level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 28 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood leptin amount male 126 days 13 1.68 ng/ml 0.34 1.21 plasma leptin analysis 0 automated plasma leptin analysis 105321 3014
SS-Chr 2BN/Mcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 8 21.1 um 0.9 2.55 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106495 3030
SS-Shc1em5Mcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 7 24.1 um 1.7 4.5 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106498 3030
SS-Shc1em4Mcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 4 24.1 um 2.4 4.8 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106502 3030
SS-Shc1em5Mcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 5 22.7 um 1.4 3.13 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106503 3030
SS/JrHsdMcwi blood T lymphocyte count controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. T cell quantity not specified 63 days 4 3.3 x 10E6 cells/ml 0.5 1.0 flow cytometry method 0.0 0 n=4-7 106512 3031
SS-Sh2b3em1Mcwi-/- spleen regulatory T cell count to total T cell count ratio controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. T cell quantity not specified 63 days 4 5.2 % 0.3 0.6 flow cytometry method 0.0 0 n=4-7 -tregs blood % 106517 3031
SS-Sh2b3em1Mcwi-/- blood regulatory T cell count to total T cell count ratio controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. T cell quantity not specified 63 days 4 4.9 % 0.1 0.2 flow cytometry method 0.0 0 n=4-7 -tregs spleen % 106519 3031
SS/JrHsdMcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 91 days 6 15sec/min for 3 hrs/day 175.5 mmHg 7.9 19.35 vascular fluid filled catheter 0.0 0 n=6-8 106522 3031
SS-Sh2b3em1Mcwi-/- mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 91 days 6 15sec/min for 3 hrs/day 135.7 mmHg 1.1 2.69 vascular fluid filled catheter 0.0 0 n=6-8 106523 3031
SS-Sh2b3em1Mcwi-/- urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (for 42 days) then controlled sodium chloride content diet (4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. urine albumin amount not specified 84 days 6 30.3 mg/d 7.0 17.15 urine albumin analysis 0.0 0 n=6-8 106529 3031
SS-Sh2b3em1Mcwi-/- kidney total CD45 positive leukocyte count controlled sodium chloride content diet (0.4 %) (for 21 days) then controlled sodium chloride content diet (4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. leukocyte quantity not specified 84 days 5 1.84 x 10E6 cells/ml 0.3 0.67 flow cytometry method 0.0 0 n=5-6 106534 3031
LN/MavRrrcAek body weight to body length (nose to rump) ratio standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 14 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. body mass male 112 days 0 13.2 g/cm 0.22 body weighing method 0.0 0 107401 3014
SBH/Ygl systolic blood pressure controlled sodium chloride content diet (8 %) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. arterial blood pressure trait male 98 days 7 181.0 mmHg 2.0 5.29 tail cuff plethysmography 0.0 0 106697 3038
SBH/Ygl body weight controlled sodium chloride content diet (8 %) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. body mass male 98 days 7 270.0 g 7.0 18.52 body weighing method 0.0 0 106701 3038
SBH/Ygl food intake weight to body weight ratio controlled sodium chloride content diet (8 %) (for 28 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. eating behavior trait male 84 days 7 10.53 g/d/100g 0.65 1.72 food intake measuring method 0.0 0 106705 3038
SBH/Ygl food intake weight to body weight ratio controlled sodium chloride content diet (8 %) (for 28 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 28 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. eating behavior trait male 84 days 7 15.72 g/d/100g 0.7 1.85 food intake measuring method 0.0 0 106707 3038
SBH/Ygl heart weight controlled sodium chloride content diet (8 %) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart mass male 98 days 7 1.23 g 0.04 0.11 post excision weight measurement 0.0 0 106709 3038
SBH/Ygl heart weight controlled sodium chloride content diet (8 %) (for 42 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart mass male 98 days 7 1.03 g 0.08 0.2 post excision weight measurement 0.0 0 106711 3038
SBH/Ygl heart left ventricle fractional shortening controlled sodium chloride content diet (8 %) (for 42 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart left ventricle end-diastolic diameter male 98 days 7 65.0 % 1.0 2.65 transthoracic echocardiography 0.0 0 106715 3038
SBH/Ygl heart left ventricle end-systolic diameter to body weight ratio controlled sodium chloride content diet (8 %) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart left ventricle end-systolic diameter male 98 days 7 0.8 mm/kg 0.07 0.19 transthoracic echocardiography 0.0 0 106721 3038
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77 days-98 days 5 MAP=.33(SP-DP) + DP 149.0 mmHg 4.0 8.94 vascular fluid filled catheter femoral artery 600.0 0 106776 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77 days-98 days 4 459.0 beats/min 9.0 18.0 vascular fluid filled catheter femoral artery 600.0 0 106782 2685
LEW/Mol kidney weight controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. kidney mass female 104 days 8 0.87 g 0.01 0.03 post excision weight measurement kidney 0.0 0 109006 3134
SR/Jr bumetanide-sensitive red blood cell Na+ export rate controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 13 194.0 umol/l/h 78.0 281.23 Na-K-Cl cotransport activity assay 0.0 0 111038 2802
SR/Jr ouabain- and bumetanide-resistant red blood cell Na+ import rate controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 13 3407.0 umol/l/h 114.0 411.03 Na+ passive permeability assay 0.0 0 111042 2802
SS/Jr ouabain- and bumetanide-resistant red blood cell Na+ import rate controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 10 5466.0 umol/l/h 525.0 1660.2 Na+ passive permeability assay 0.0 0 111044 2802
SR/Jr ouabain-sensitive red blood cell K+ import rate controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 13 4255.0 umol/l/h 130.0 468.72 Na+/K+ ATPase activity assay 0.0 0 111046 2802
SR/Jr bumetanide-sensitive red blood cell K+ import rate controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 16 773.0 umol/l/h 61.0 244.0 Na-K-Cl cotransport activity assay 0.0 0 111049 2802
SR/Jr bumetanide-sensitive red blood cell K+ import rate controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 13 698.0 umol/l/h 73.0 263.21 Na-K-Cl cotransport activity assay 0.0 0 111050 2802
MWF/Fub systolic blood pressure controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. arterial blood pressure trait female 100 days-103 days 8 134.0 mmHg 3.0 8.49 tail cuff plethysmography tail 0.0 0 109022 3134
BN.GH-(D2Rat22-D2Mgh11)(D18Rat41-D18Mgh4)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 3 days) then controlled sodium chloride content diet (4 %) (for 23 days) Bilusic M, et al., Croat Med J. 2008 Oct;49(5):586-99. arterial blood pressure trait male 155 days-169 days 16 serial mean 110.1 mmHg 1.95 7.8 radiotelemetry left femoral artery 10 seconds every two minutes for 4 hrs/day every other day for 23 days 0 Dataquest IV system; anesthetized by 1% isoflurane, recover for 3 days 11559 101
BN.GH-(D2Rat22-D2Mgh11)(D6Mit12-D6Rat15)(D18Rat41-D18Mgh4)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 3 days) then controlled sodium chloride content diet (4 %) (for 23 days) Bilusic M, et al., Croat Med J. 2008 Oct;49(5):586-99. arterial blood pressure trait male 155 days-169 days 16 serial mean 93.5 mmHg 2.15 8.6 radiotelemetry left femoral artery 10 seconds every two minutes for 4 hrs/day every other day for 23 days 0 Dataquest IV system; anesthetized by 1% isoflurane, recover for 3 days 11560 101
BN/Elh mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 3 days) then controlled sodium chloride content diet (4 %) (for 23 days) Bilusic M, et al., Croat Med J. 2008 Oct;49(5):586-99. arterial blood pressure trait male 155 days-169 days 21 serial mean 93.0 mmHg 2.03 9.3 radiotelemetry left femoral artery 10 seconds every two minutes for 4 hrs/day every other day for 23 days 0 Dataquest IV system; anesthetized by 1% isoflurane, recover for 3 days 11561 101
SR/Jr body weight controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. body mass not specified 84 days 5 349.0 g 10.29 23.0 body weighing method 0.0 0 103142 2787
SS/Jr heart weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart mass not specified 84 days 5 4.18 g/kg 0.3 0.68 post excision weight measurement 0.0 0 103145 2787
SS/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then pentobarbital (20 mg/kg) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 84 days 5 411.0 beats/min 19.68 44.0 vascular transducer tipped catheter 0.0 0 103147 2787
SR/Jr left ventricular end-diastolic blood pressure controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then pentobarbital, sodium (20 mg/kg) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart left ventricular blood pressure trait not specified 84 days 5 1.0 mmHg 0.45 1.0 vascular transducer tipped catheter 0.0 0 103152 2787
SR/Jr maximum rate of positive change in left ventricular blood pressure controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then pentobarbital, sodium (20 mg/kg) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart left ventricular blood pressure trait not specified 84 days 5 LVdP/dtmax 8600.0 mmHg/s 715.54 1600.0 vascular transducer tipped catheter 0.0 0 E3 X mmHg/s 103154 2787
SS/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 368.0 beats/min 3.13 7.0 intra-aortic thoracic radiotelemetry 0.0 0 103155 2787
SR/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (for 0.4 hours) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 389.0 beats/min 10.73 24.0 intra-aortic thoracic radiotelemetry 0.0 5 min 103162 2787
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 103.0 mmHg 0.45 1.0 intra-aortic thoracic radiotelemetry 0.0 0 103172 2787
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) then ambient air (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 139.0 mmHg 2.24 5.0 intra-aortic thoracic radiotelemetry 0.0 0 103173 2787
SS/Jr respiration rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. respiratory function trait not specified 86 days 5 sampling once per minute 123.0 breaths/min 1.34 3.0 spirometry 0.0 0 103175 2787
SR/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) (between 0.5 and 0.9 hours) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 436.0 beats/min 8.5 19.0 intra-aortic thoracic radiotelemetry 0.0 25 min 103193 2787
SS/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) (between 0.9 and 1.3 hours) then 10% CO2, 20% O2, 70% N2 (for 0.4 hours) then ambient air (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 4 sampling once per minute 471.0 beats/min 7.5 15.0 intra-aortic thoracic radiotelemetry 0.0 25 min 103196 2787
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 4 sampling once per minute 128.0 mmHg 1.5 3.0 intra-aortic thoracic radiotelemetry 0.0 0 103198 2787
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 4 sampling once per minute 135.0 mmHg 1.5 3.0 intra-aortic thoracic radiotelemetry 0.0 0 103202 2787
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) then ambient air (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 5 sampling once per minute 115.0 mmHg 2.24 5.0 intra-aortic thoracic radiotelemetry 0.0 0 103205 2787
SR/JrHsd body weight controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 226.0 g 4.7 body weighing method 0.0 0 102183 2681
SR/JrHsd body weight controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 276.0 g 11.0 body weighing method 0.0 0 102185 2681
SR/JrHsd single kidney wet weight controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 0.85 g 0.01 post excision weight measurement 0.0 0 102197 2681
SR/JrHsd single kidney wet weight controlled sodium chloride content diet (4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 1.02 g 0.03 post excision weight measurement 0.0 0 102198 2681
SS/JrHsd single kidney wet weight controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 1.26 g 0.09 post excision weight measurement 0.0 0 102202 2681
SS/JrHsd single kidney wet weight controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 0.91 g 0.01 post excision weight measurement 0.0 0 102203 2681
SS/JrHsd single kidney wet weight controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. kidney mass female 0 days 0 1.1 g 0.07 post excision weight measurement 0.0 0 102205 2681
SS/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female 0 days 0 135.0 mmHg 4.0 vascular fluid filled catheter 0.0 0 102211 2681
SS/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 2.54 ml/min/g 0.13 inulin analysis by liquid phase colorimetry 0.0 0 102217 2681
SR/NEisSlc end-diastolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 77 days 10 0.13 ml 0.02 0.07 volume pressure recording 0.0 0 102516 2690
SR/NEisSlc end-diastolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 126 days 10 0.19 ml 0.02 0.07 volume pressure recording 0.0 0 102517 2690
SS/NEisSlc heart left ventricle end-diastolic elastance controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 126 days 10 36.0 mmHg/ml 3.48 11.0 volume pressure recording 0.0 0 102529 2690
SS/NEisSlc heart left ventricle end-diastolic elastance controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 58.0 mmHg/ml 6.64 21.0 volume pressure recording 0.0 0 102530 2690
SS/NEisSlc heart left ventricle end-diastolic elastance controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 126 days 10 47.0 mmHg/ml 6.01 19.0 volume pressure recording 0.0 0 102531 2690
SS/NEisSlc heart left ventricle diastolic volume-axis intercept controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 77 days 10 0.01 ml 0.0 0.01 volume pressure recording 0.0 0 102534 2690
SR/NEisSlc kidney medullary adrenomedullin level controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 77 days 7 0.34 fmol/mg 0.01 0.02 radioimmunoassay 0.0 0 102451 2689
SS/NEisSlc kidney medullary adrenomedullin level controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 77 days 8 0.45 fmol/mg 0.01 0.04 radioimmunoassay 0.0 0 102452 2689
SS/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 77 days 14 348.0 g 4.01 15.0 body weighing method 0.0 0 102454 2689
SS/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77 days 14 1.4 mEq/d 0.13 0.5 automated urine sodium analysis 0.0 0 102469 2689
SR/NEisSlc heart left ventricle weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 126 days 10 0.94 g 0.0 0.0 post excision weight measurement 0.0 0 102485 2690
SS/NEisSlc heart left ventricle weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 126 days 10 1.31 g 0.0 0.01 post excision weight measurement 0.0 0 102487 2690
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. arterial blood pressure trait male 77 days 10 undefined 233.0 mmHg 0.63 2.0 tail cuff plethysmography 0.0 0 102494 2690
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 126 days 10 415.0 beats/min 8.85 28.0 tail cuff plethysmography 0.0 0 102497 2690
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 126 days 10 481.0 beats/min 13.91 44.0 tail cuff plethysmography 0.0 0 102499 2690
SR/NEisSlc left ventricular systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 105.0 mmHg 5.38 17.0 volume pressure recording 0.0 0 102500 2690
SS/NEisSlc left ventricular systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 149.0 mmHg 6.01 19.0 volume pressure recording 0.0 0 102502 2690
SR/Hsd mean arterial blood pressure controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. arterial blood pressure trait male 91 days 8 114.0 mmHg 2.12 6.0 tail cuff plethysmography 0.0 0 102269 2683
SS body weight controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. body mass male 91 days 8 309.0 g 6.36 18.0 body weighing method 0.0 0 102272 2683
SS.BN-(D13Hmgc354-D13Rat32)/Mcwi urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium chloride content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. urine albumin amount male 60 days-67 days 16 150.0 mg/d 27.0 108.0 urine microalbumin analysis 0.0 0 strain 26-J 98635 2098
SR/Jr heart weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. heart mass male 63 days 16 2.53 g/kg 0.02 0.08 post excision weight measurement 0.0 0 103238 2802
SR/Jr single kidney wet weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. kidney mass male 63 days 16 7.24 g/kg 0.1 0.4 post excision weight measurement 0.0 0 103242 2802
SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi diastolic blood pressure controlled sodium chloride content diet (0.4 %) (between 23 and 32 days) then controlled sodium chloride content diet (8 %) (for 14 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 58 days-67 days 11 serial mean 120.0 mmHg 4.0 13.27 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 carotid a. to thoracic aorta implant strain 26-P 98510 2079
SS.BN-(D13Hmgc37-D13Got22)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 68 days) then controlled sodium chloride content diet (8 %) (for 21 days) Moreno C, et al., Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1530-5. doi: 10.1152/ajpheart.01026.2010. Epub 2011 Jan 21. arterial blood pressure trait male 89 days 15 serial mean 162.0 mmHg 4.0 15.49 intra-aortic abdominal radiotelemetry via femoral cannulation 10800.0 0 strain 5-1 98674 2138
SS/JrHsdMcwi urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (8 %) (for 21 days) Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1. urine albumin amount female 91 days 13 135.0 mg/d 15.0 54.08 urine microalbumin analysis 1.0 0 98710 2141
SS.BN-(D13Rat25-rs106935835)/Mcwi urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (8 %) (for 21 days) Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1. urine albumin amount male 91 days 11 343.0 mg/d 41.0 135.98 urine microalbumin analysis 1.0 0 strain 9E 98715 2141
LN/MavRrrcAek heart rate standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. heart pumping trait male 119 days 14 346.5 beats/min 2.7 10.1 intra-aortic abdominal radiotelemetry via femoral cannulation 0.0 0 102616 3014
LH/MavRrrcAek body weight area under curve (AUC) standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. body mass male 21 days-126 days 0 body weight X week = growth AUC 4.1351184E7 g x min 396144.0 body weighing method 0.0 0 growth auc 102617 3014
LN/MavRrrcAek body weight area under curve (AUC) standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. body mass male 21 days-126 days 0 body weight X week = growth AUC 2.8740096E7 g x min 358848.0 body weighing method 0.0 0 growth auc 102618 3014
LH/MavRrrcAek combined renal and gonadal fat pad weight standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. fat pad morphology trait male 126 days 9 1.43 g 0.09 0.27 post excision weight measurement 0.0 0 combined renal and gonadal fat pad weight (CMO:0003886) 102619 3014
LN/MavRrrcAek combined renal and gonadal fat pad weight standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. fat pad morphology trait male 126 days 14 0.72 g 0.03 0.11 post excision weight measurement 0.0 0 combined renal and gonadal fat pad weight (CMO:0003886) 102620 3014
SS plasma urotensin II level controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. blood urotensin II amount male 91 days 8 52.0 pg/ml 4.38 12.4 radioimmunoassay 0.0 0 102276 2683
SR/Hsd plasma urotensin II level controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. blood urotensin II amount male 91 days 8 60.0 pg/ml 2.26 6.4 radioimmunoassay 0.0 0 102277 2683
SS urine sodium level controlled sodium chloride content diet (8 %) (for 28 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. urine sodium amount male 77 days 8 1.9 mmol/l 0.07 0.2 urine sodium analysis 0.0 0 102282 2683
SS urine sodium level controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. urine sodium amount male 91 days 8 1.7 mmol/l 0.07 0.2 urine sodium analysis 0.0 0 102284 2683
SS creatinine clearance controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. glomerular filtration trait male 91 days 8 2.8 ml/min 0.07 0.2 urine creatinine analysis 0.0 0 102288 2683
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77 days 7 377.0 beats/min 8.32 22.0 tail cuff plethysmography 0.0 0 102415 2689
SR/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 70 days 8 4.09 g/kg 0.05 0.13 post excision weight measurement 0.0 0 102425 2689
SS/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 77 days 8 4.64 g/kg 0.07 0.19 post excision weight measurement 0.0 0 102428 2689
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 63 days 7 mean of 3 samples of undefined duration serial mean 119.0 mmHg 3.02 8.0 tail cuff plethysmography 0.0 0 102429 2689
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77 days 7 mean of 3 samples of undefined duration serial mean 125.0 mmHg 3.02 8.0 tail cuff plethysmography 0.0 0 102433 2689
SS/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77 days 8 1.2 mEq/d 0.11 0.3 automated urine sodium analysis 0.0 0 102440 2689
SS/NEisSlc kidney cortical adrenomedullin level controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 70 days 7 0.61 fmol/mg 0.03 0.09 radioimmunoassay 0.0 0 102444 2689
SR/NEisSlc kidney medullary adrenomedullin level controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 63 days 7 0.31 fmol/mg 0.02 0.06 radioimmunoassay 0.0 0 102447 2689
SS/NEisSlc kidney medullary adrenomedullin level controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 63 days 8 0.31 fmol/mg 0.02 0.05 radioimmunoassay 0.0 0 102448 2689
SS/NEisSlc kidney medullary adrenomedullin level controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 70 days 7 0.31 fmol/mg 0.01 0.02 radioimmunoassay 0.0 0 102450 2689
SS/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 7 days) then 0.9% sodium chloride solution (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 63 days 14 5.2 mg/d/100 g 0.45 1.7 urine protein analysis 0.0 0 102472 2689
SS/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 7 days) then adrenomedulin (400 ng/hr) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 63 days 14 3.5 mg/d/100 g 0.27 1.0 urine protein analysis 0.0 0 102473 2689
SS/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 14 days) then adrenomedulin (400 ng/hr) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 70 days 14 4.5 mg/d/100 g 0.32 1.2 urine protein analysis 0.0 0 102476 2689
SS/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 77 days 14 7.8 mg/d/100 g 0.72 2.7 urine protein analysis 0.0 0 102478 2689
SR/Jr body weight controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. body mass male 63 days 16 218.0 g 9.0 36.0 body weighing method 0.0 0 103234 2802
SS/Jr body weight controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. body mass male 63 days 15 271.0 g 10.0 38.73 body weighing method 0.0 0 103236 2802
SS-Nppaem4Mcwi-/- urine creatinine excretion rate controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine creatinine amount male 60 days-69 days 0 10.1 mg/d 0.3 urine creatinine analysis 0.0 0 98439 2059
SS/Jr heart weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. heart mass male 63 days 15 2.59 g/kg 0.04 0.15 post excision weight measurement 0.0 0 103240 2802
SS-Nppaem4Mcwi-/- urine sodium excretion rate controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine sodium amount male 60 days-69 days 0 8.6 mEq/d 1.0 urine electrolyte analysis 0.0 0 98446 2059
SS-Nppbem2Mcwi+/+ heart rate controlled sodium chloride content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 98 days 4 420.0 beats/min 7.0 14.0 echocardiography 0.0 0 99728 2319
SS/Jr systolic blood pressure controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 10 189.0 mmHg 6.0 23.24 vascular transducer tipped catheter 0.0 0 103249 2802
SR/Jr diastolic blood pressure controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 13 85.0 mmHg 4.0 14.42 vascular transducer tipped catheter 0.0 0 103255 2802
SR/Jr plasma triglyceride level controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. blood triglyceride amount male 63 days 13 0.61 mmol/l 0.16 0.58 plasma triglyceride analysis 0.0 0 103259 2802
SR/Jr plasma total cholesterol level controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. blood cholesterol amount male 63 days 16 69.88 mg/dl 6.95 27.8 plasma total cholesterol measurement test 0.0 0 103262 2802
SS/Jr plasma total cholesterol level controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. blood cholesterol amount male 63 days 15 79.15 mg/dl 4.63 17.94 plasma total cholesterol measurement test 0.0 0 103264 2802
SS/Jr plasma total cholesterol level controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. blood cholesterol amount male 63 days 10 111.97 mg/dl 13.51 42.73 plasma total cholesterol measurement test 0.0 0 103265 2802
SR/Jr hematocrit controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte quantity male 63 days 16 45.8 % 0.4 1.6 hematocrit analysis 0.0 0 103266 2802
SS/Jr hematocrit controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte quantity male 63 days 15 48.8 % 0.5 1.94 hematocrit analysis 0.0 0 103268 2802
SS/Jr hematocrit controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte quantity male 63 days 10 47.0 % 2.2 6.96 hematocrit analysis 0.0 0 103269 2802
SS.BN-(D13Mit5-D13Rat32)/Mcwi diastolic blood pressure controlled sodium chloride content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium chloride content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60 days-67 days 14 serial mean 173.0 mmHg 16.0 59.87 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 intra-carotid radiotelemetry strain 26-H 98589 2098
SR/Jr minimum rate of positive change in left ventricular blood pressure controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then pentobarbital, sodium (20 mg/kg) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart left ventricular blood pressure trait not specified 84 days 5 LVdP/dtmin 8.2 10E3 mmHg/s 4.47 1.2 vascular transducer tipped catheter 0.0 0 minimum rate of positive change in left ventricular blood pressure 106818 2787
SS-Chr 13BN/McwiCrl heart rate controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77 days-98 days 4 408.0 beats/min 6.0 12.0 vascular fluid filled catheter femoral artery 600.0 0 106772 2685
SBH/Ygl blood glucose level controlled sodium chloride content diet (0.65 %) (for 98 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. blood glucose amount male 98 days 7 113.4 mg/dl 3.6 9.52 blood glucose test strip read by electrochemical glucometer 0.0 0 106692 3038
SBH/Ygl body weight controlled sodium chloride content diet (0.65 %) (for 98 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. body mass male 98 days 7 295.0 g 10.0 26.46 body weighing method 0.0 0 106700 3038
SBH/Ygl body weight controlled sodium chloride content diet (8 %) (for 42 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. body mass male 98 days 7 216.0 g 13.0 34.39 body weighing method 0.0 0 106703 3038
SBH/Ygl heart weight controlled sodium chloride content diet (0.65 %) (for 98 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart mass male 98 days 7 1.07 g 0.07 0.18 post excision weight measurement 0.0 0 106710 3038
SBH/Ygl heart left ventricle fractional shortening controlled sodium chloride content diet (0.65 %) (for 98 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart left ventricle end-diastolic diameter male 98 days 7 66.0 % 1.0 2.65 transthoracic echocardiography 0.0 0 106712 3038
SBH/Ygl heart left ventricle fractional shortening controlled sodium chloride content diet (0.65 %) (for 98 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart left ventricle end-diastolic diameter male 98 days 7 61.0 % 4.0 10.58 transthoracic echocardiography 0.0 0 106714 3038
SBH/Ygl heart left ventricle end-diastolic diameter to body weight ratio controlled sodium chloride content diet (0.65 %) (for 98 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart left ventricle end-diastolic diameter male 98 days 7 1.9 mm/kg 0.01 0.03 transthoracic echocardiography 0.0 0 106716 3038
SBH/Ygl heart left ventricle end-diastolic diameter to body weight ratio controlled sodium chloride content diet (0.65 %) (for 98 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart left ventricle end-diastolic diameter male 98 days 7 2.6 mm/kg 0.2 0.53 transthoracic echocardiography 0.0 0 106718 3038
SBH/Ygl heart left ventricle end-systolic diameter to body weight ratio controlled sodium chloride content diet (0.65 %) (for 98 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart left ventricle end-systolic diameter male 98 days 7 0.65 mm/kg 0.02 0.05 transthoracic echocardiography 0.0 0 106720 3038
SBH/Ygl heart left ventricle end-systolic diameter to body weight ratio controlled sodium chloride content diet (0.65 %) (for 98 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart left ventricle end-systolic diameter male 98 days 7 0.99 mm/kg 0.1 0.26 transthoracic echocardiography 0.0 0 106722 3038
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77 days-98 days 5 454.0 beats/min 7.0 15.65 vascular fluid filled catheter femoral artery 600.0 0 106775 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) then kynurenate (0.14 ug/min) (for 0.2 hours) then candesartan (0.5 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77 days-98 days 5 410.0 beats/min 15.0 33.54 vascular fluid filled catheter femoral artery 600.0 0 106784 2685
SS-Shc1em1Mcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 5 23.4 um 1.4 3.13 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106496 3030
SS/JrHsdMcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 8 24.1 um 0.8 2.26 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106499 3030
SS-Chr 2BN/Mcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 6 20.7 um 1.8 4.41 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106505 3030
SS/JrHsdMcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 70 days 6 15sec/min for 3 hrs/day for 7days 127.5 mmHg 1.5 3.67 vascular fluid filled catheter 0.0 0 n=6-8 106520 3031
SR/Jr ouabain-sensitive red blood cell Na+ export rate controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 16 3500.0 umol/l/h 91.0 200.0 Na+/K+ ATPase activity assay 0.0 0 110981 2802
MWF/Fub kidney weight controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. kidney mass female 104 days 8 0.69 g 0.01 0.03 post excision weight measurement kidney 0.0 0 109010 3134
SS/Jr ouabain-sensitive red blood cell Na+ export rate controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 15 3908.0 umol/l/h 104.0 402.79 Na+/K+ ATPase activity assay 0.0 0 111035 2802
SR/Jr ouabain-sensitive red blood cell Na+ export rate controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 13 3483.0 umol/l/h 104.0 374.98 Na+/K+ ATPase activity assay 0.0 0 111034 2802
SR/Jr bumetanide-sensitive red blood cell Na+ export rate controlled sodium chloride content diet (0.3 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. erythrocyte ion transport trait male 63 days 16 163.0 umol/l/h 70.0 280.0 Na-K-Cl cotransport activity assay 0.0 0 111037 2802
LEW/Mol kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. kidney mass female 104 days 8 4.48 mg/g 0.0 0.0 post excision weight measurement kidney 0.0 0 109014 3134
GH/Omr mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 3 days) then controlled sodium chloride content diet (4 %) (for 23 days) Bilusic M, et al., Croat Med J. 2008 Oct;49(5):586-99. arterial blood pressure trait male 155 days-169 days 20 serial mean 147.5 mmHg 2.06 9.2 radiotelemetry left femoral artery 10 seconds every two minutes for 4 hrs/day every other day for 23 days 0 Dataquest IV system; anesthetized by 1% isoflurane, recover for 3 days 11556 101
SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi diastolic blood pressure controlled sodium chloride content diet (0.4 %) (between 23 and 32 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 44 days-53 days 11 serial mean 89.0 mmHg 2.0 6.63 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 carotid a. to thoracic aorta implant strain 26-P 98489 2079
SS/Jr body weight controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. body mass not specified 84 days 5 332.0 g 22.36 50.0 body weighing method 0.0 0 103141 2787
SS/Jr heart weight controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart mass not specified 84 days 5 1.36 g 0.02 0.06 post excision weight measurement 0.0 0 103143 2787
SR/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then pentobarbital (20 mg/kg) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 84 days 5 415.0 beats/min 9.39 21.0 vascular transducer tipped catheter 0.0 0 103148 2787
SS/Jr maximum rate of positive change in left ventricular blood pressure controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then pentobarbital, sodium (20 mg/kg) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart left ventricular blood pressure trait not specified 84 days 5 LVdP/dtmax 13200.0 mmHg/s 1207.48 2700.0 vascular transducer tipped catheter 0.0 0 E3 X mmHg/s 103153 2787
SR/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 310.0 beats/min 4.47 10.0 intra-aortic thoracic radiotelemetry 0.0 0 103160 2787
SS/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) (between 0.5 and 0.9 hours) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 4 sampling once per minute 428.0 beats/min 6.0 12.0 intra-aortic thoracic radiotelemetry 0.0 25 min 103192 2787
SR/Jr heart rate controlled sodium chloride content diet (0.3 %) (for 21 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) (between 0.9 and 1.3 hours) then 10% CO2, 20% O2, 70% N2 (for 0.4 hours) then ambient air (between 0 and 0.4 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. heart pumping trait not specified 86 days 5 sampling once per minute 463.0 beats/min 1.79 4.0 intra-aortic thoracic radiotelemetry 0.0 25 min 103197 2787
SS/Jr mean arterial blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 42 days) then atropine (1 mg/kg) then 10% CO2, 20% O2, 70% N2 (between 0 and 0.1 hours) Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18. arterial blood pressure trait not specified 86 days 4 sampling once per minute 135.0 mmHg 1.5 3.0 intra-aortic thoracic radiotelemetry 0.0 0 103200 2787
SR/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 77 days 19 370.0 g 2.52 11.0 body weighing method 0.0 0 102453 2689
SS/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) then adrenomedulin (400 ng/hr) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77 days 14 332.0 beats/min 9.35 35.0 tail cuff plethysmography 0.0 0 102458 2689
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77 days 19 2.2 mEq/d 0.16 0.7 automated urine sodium analysis 0.0 0 102468 2689
SR/NEisSlc body weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. body mass male 126 days 10 483.0 g 5.69 18.0 body weighing method 0.0 0 102481 2690
SS/NEisSlc body weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. body mass male 126 days 10 298.0 g 4.43 14.0 body weighing method 0.0 0 102483 2690
SR/NEisSlc heart left ventricle weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 77 days 10 0.83 g 0.0 0.0 post excision weight measurement 0.0 0 102484 2690
SR/NEisSlc heart left ventricle weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 77 days 10 2.33 mg/g 0.03 0.09 post excision weight measurement 0.0 0 102488 2690
SS/NEisSlc heart left ventricle weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 77 days 10 3.35 mg/g 0.12 0.38 post excision weight measurement 0.0 0 102490 2690
SS/NEisSlc left ventricular systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 126 days 10 107.0 mmHg 5.69 18.0 volume pressure recording 0.0 0 102501 2690
SS/NEisSlc left ventricular end-diastolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 126 days 10 2.8 mmHg 0.85 2.7 volume pressure recording 0.0 0 102509 2690
SS/NEisSlc left ventricular end-diastolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 5.4 mmHg 0.7 2.2 volume pressure recording 0.0 0 102510 2690
SR/NEisSlc end-systolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 126 days 10 0.09 ml 0.02 0.06 volume pressure recording 0.0 0 102513 2690
SS/NEisSlc end-diastolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 77 days 10 0.1 ml 0.01 0.02 volume pressure recording 0.0 0 102518 2690
SS/NEisSlc heart left ventricle end-systolic elastance controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 126 days 10 2092.0 mmHg/ml 237.49 751.0 volume pressure recording 0.0 0 102521 2690
SS/NEisSlc heart left ventricle end-systolic elastance controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 3355.0 mmHg/ml 331.41 1048.0 volume pressure recording 0.0 0 102522 2690
SS/NEisSlc heart left ventricle end-systolic elastance controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 126 days 10 1424.0 mmHg/ml 118.59 375.0 volume pressure recording 0.0 0 102523 2690
SR/NEisSlc heart left ventricle end-diastolic elastance controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 32.0 mmHg/ml 5.69 18.0 volume pressure recording 0.0 0 102528 2690
SR/NEisSlc heart left ventricle diastolic volume-axis intercept controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 126 days 10 0.09 ml 0.02 0.06 volume pressure recording 0.0 0 102533 2690
SS/NEisSlc time constant of left ventricular pressure decay controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 126 days 10 19.4 ms 0.66 2.1 volume pressure recording 0.0 0 102539 2690
SR/JrHsd body weight controlled sodium chloride content diet (4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 269.0 g 7.3 body weighing method 0.0 0 102186 2681
SS/JrHsd body weight controlled sodium chloride content diet (4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. body mass female 0 days 0 297.0 g 5.1 body weighing method 0.0 0 102192 2681
SS/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female 0 days 0 132.0 mmHg 2.0 vascular fluid filled catheter 0.0 0 102212 2681
SS.BN-(D13Rat130-D13Rat32)/Mcwi urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium chloride content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. urine albumin amount male 60 days-67 days 12 113.0 mg/d 10.0 34.64 urine microalbumin analysis 0.0 0 strain 26-K 98636 2098
SS.BN-(D13Got45-D13Rat32)/Mcwi urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium chloride content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. urine albumin amount male 60 days-67 days 12 165.0 mg/d 26.0 90.07 urine microalbumin analysis 0.0 0 strain 26-L 98637 2098
SR/Hsd body weight controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. body mass male 91 days 8 308.0 g 10.61 30.0 body weighing method 0.0 0 102273 2683
SS.BN-(D13Rat111-D13Rat115)/Mcwi urine total protein excretion rate controlled sodium chloride content diet (0.4 %) (for 68 days) then controlled sodium chloride content diet (8 %) (for 21 days) Moreno C, et al., Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1530-5. doi: 10.1152/ajpheart.01026.2010. Epub 2011 Jan 21. total urine protein amount male 89 days 11 335.0 mg/d 33.0 109.45 Bradford protein assay 1.0 0 strain 5-8 98696 2138
SS.BN-(D13Rat25-rs106935835)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (8 %) (for 21 days) Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1. arterial blood pressure trait female 91 days 8 serial mean 186.0 mmHg 3.0 8.49 intra-aortic abdominal radiotelemetry via femoral cannulation 10800.0 0 strain 9E 98706 2141
SS.BN-(D13Hmgc885-D13Hmgc664)/Mcwi systolic blood pressure controlled sodium chloride content diet (0.4 %) (between 23 and 32 days) then controlled sodium chloride content diet (8 %) (for 14 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 58 days-67 days 10 serial mean 168.0 mmHg 5.0 15.81 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 carotid a. to thoracic aorta implant strain 26-R 98505 2079
SR/Jr heart weight to body weight ratio controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. heart mass male 63 days 13 2.56 g/kg 0.04 0.14 post excision weight measurement 0.0 0 103239 2802
SS/Jr heart weight to body weight ratio controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. heart mass male 63 days 10 3.1 g/kg 0.06 0.19 post excision weight measurement 0.0 0 103241 2802
SS.BN-(D13Got42-D13Hmgc354)/Mcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium chloride content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60 days-67 days 16 serial mean 161.0 mmHg 5.0 20.0 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 intra-carotid radiotelemetry strain 26-D 98556 2098
LN/MavRrrcAek plasma glucose level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 14 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood glucose amount male 112 days 14 155.5 mg/dl 7.7 28.81 plasma glucose analysis 0.0 0 102624 3014
LN/MavRrrcAek plasma triglyceride level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 14 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood triglyceride amount male 112 days 14 0.4 mmol/l 0.05 0.19 plasma triglyceride analysis 0.0 0 102628 3014
LN/MavRrrcAek plasma triglyceride level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 28 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood triglyceride amount male 126 days 14 0.39 mmol/l 0.05 0.19 plasma triglyceride analysis 0.0 0 102630 3014
LH/MavRrrcAek plasma total cholesterol level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 14 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood cholesterol amount male 112 days 9 62.55 mg/dl 7.72 23.17 plasma total cholesterol measurement test 0.0 0 102633 3014
LN/MavRrrcAek plasma total cholesterol level standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 14 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. blood cholesterol amount male 112 days 14 42.47 mg/dl 4.63 17.34 plasma total cholesterol measurement test 0.0 0 102634 3014
SS/JrHsdMcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium chloride content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60 days-67 days 12 serial mean 177.0 mmHg 4.0 13.86 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 intra-carotid radiotelemetry 98551 2098
SS-Nppbem2Mcwi+/+ ejection fraction controlled sodium chloride content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. cardiac output trait male 98 days 4 77.3 % 3.09 6.18 echocardiography 0.0 0 99722 2319
SS-Nppbem2Mcwi-/- ejection fraction controlled sodium chloride content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. cardiac output trait male 98 days 4 83.0 % 1.41 2.82 echocardiography 0.0 0 99723 2319
SS-Nppbem2Mcwi+/+ heart left ventricle weight controlled sodium chloride content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle mass male 98 days 4 1.47 g 0.11 0.22 echocardiography 0.0 0 99726 2319
SS/Hsd urine total protein excretion rate controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. total urine protein amount male 60 days-69 days 0 91.0 mg/d 5.0 urine total protein analysis 0.0 0 98436 2059
SR/Jr body weight controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. body mass male 63 days 13 225.0 g 8.0 28.84 body weighing method 0.0 0 103235 2802
SR/Jr systolic blood pressure controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 13 138.0 mmHg 3.0 10.82 vascular transducer tipped catheter 0.0 0 103247 2802
SR/Jr mean arterial blood pressure controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. arterial blood pressure trait male 63 days 13 107.0 mmHg 4.0 14.42 vascular transducer tipped catheter 0.0 0 103251 2802
SR/Jr plasma total cholesterol level controlled sodium chloride content diet (8 %) (for 35 days) Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404. blood cholesterol amount male 63 days 13 72.59 mg/dl 2.7 9.74 plasma total cholesterol measurement test 0.0 0 103263 2802
SS urine urotensin II level to urine creatinine level ratio controlled sodium chloride content diet (8 %) (for 28 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. urine urotensin II amount male 77 days 8 136.7 ng/g 16.05 45.4 radioimmunoassay 0.0 0 102278 2683
SR/Hsd urine urotensin II level to urine creatinine level ratio controlled sodium chloride content diet (8 %) (for 28 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. urine urotensin II amount male 77 days 8 181.3 ng/g 29.66 83.9 radioimmunoassay 0.0 0 102279 2683
SR/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 70 days 8 309.0 g 3.89 11.0 body weighing method 0.0 0 102407 2689
SS/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 77 days 8 342.0 g 4.24 12.0 body weighing method 0.0 0 102410 2689
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 63 days 7 389.0 beats/min 9.07 24.0 tail cuff plethysmography 0.0 0 102411 2689
SR/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 63 days 7 3.69 g/kg 0.1 0.26 post excision weight measurement 0.0 0 102423 2689
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 70 days 8 mean of 3 samples of undefined duration serial mean 124.0 mmHg 3.18 9.0 tail cuff plethysmography 0.0 0 102431 2689
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77 days 8 mean of 3 samples of undefined duration serial mean 169.0 mmHg 2.47 7.0 tail cuff plethysmography 0.0 0 102434 2689
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77 days 7 2.7 mEq/d 0.49 1.3 automated urine sodium analysis 0.0 0 102439 2689
SS/NEisSlc kidney cortical adrenomedullin level controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 63 days 8 0.62 fmol/mg 0.02 0.05 radioimmunoassay 0.0 0 102442 2689
SR/NEisSlc kidney cortical adrenomedullin level controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 70 days 8 0.56 fmol/mg 0.02 0.06 radioimmunoassay 0.0 0 102443 2689
SR/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 14 days) then 0.9% sodium chloride solution (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 70 days 19 3.2 mg/d/100 g 0.21 0.9 urine protein analysis 0.0 0 102474 2689
LH/MavRrrcAek body weight to body length (nose to rump) ratio standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 14 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. body mass male 112 days 0 17.0 g/cm 0.21 body weighing method 0.0 0 107400 3014
LN/MavRrrcAek maximum slope of body weight growth curve standard rat chow (for 98 days) then controlled sodium chloride content diet (4 %) (for 21 days) Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8. body mass male 21 days-126 days 0 y=mx+c 35.2 g/week 0.52 body weighing method 0.0 0 maximum slope of body weight growth curve (CMO:0003452) 107403 3014
SBH/Ygl heart weight controlled sodium chloride content diet (0.65 %) (for 98 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. heart mass male 98 days 7