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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1Condition 2
8serum creatinine levelLOU/MWslmale0.76614mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)109775rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)
8serum creatinine levelLOU/MWslmale0.78761mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 mg/kg) 109776rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 mg/kg)
8serum creatinine levelLOU/MWslmale0.70738mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 mg/kg) (for 7 days)109777rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 mg/kg) (for 7 days)
8serum creatinine levelLOU/MWslmale0.791mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 mg/kg) (for 14 days)109778rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 mg/kg) (for 14 days)
5serum creatinine levelLOU/MWslmale0.63054mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 mg/kg) (for 42 days)109779rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 mg/kg) (for 42 days)
3serum creatinine levelLOU/MWslmale0.57517mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 mg/kg) (for 56 days)109780rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 mg/kg) (for 56 days)
8serum creatinine levelLOU/MWslmale0.82942mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (1 mg/kg) 109781rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (1 mg/kg)
8serum creatinine levelLOU/MWslmale0.6893mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (1 mg/kg) (for 7 days)109782rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (1 mg/kg) (for 7 days)
8serum creatinine levelLOU/MWslmale0.68139mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (1 mg/kg) (for 14 days)109783rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (1 mg/kg) (for 14 days)
6serum creatinine levelLOU/MWslmale0.44861mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (1 mg/kg) (for 42 days)109784rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (1 mg/kg) (for 42 days)
8serum creatinine levelLOU/MWslmale0.59438mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (1 mg/kg) (for 56 days)109785rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (1 mg/kg) (for 56 days)
7serum creatinine levelLOU/MWslmale0.76049mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (2 mg/kg) 109786rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (2 mg/kg)
8serum creatinine levelLOU/MWslmale0.63732mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (2 mg/kg) (for 7 days)109787rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (2 mg/kg) (for 7 days)
6serum creatinine levelLOU/MWslmale0.5876mg/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (2 mg/kg) (for 14 days)109788rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (2 mg/kg) (for 14 days)
6serum creatinine levelLOU/MWslmale0.678mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109622rat IgM immunocytoma cells (1 x 10E4 cells)
6serum creatinine levelLOU/MWslmale0.58986mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (0.5 mg/kg) (for 17 days)109623rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (0.5 mg/kg) (for 17 days)
6serum creatinine levelLOU/MWslmale0.8136mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (0.5 mg/kg) (for 33 days)109624rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (0.5 mg/kg) (for 33 days)
2serum creatinine levelLOU/MWslmale0.6893mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (0.5 mg/kg) (for 40 days)109625rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (0.5 mg/kg) (for 40 days)
6serum creatinine levelLOU/MWslmale0.61359mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109626rat IgM immunocytoma cells (1 x 10E4 cells)
5serum creatinine levelLOU/MWslmale0.47008mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (1 mg/kg) (for 33 days)109627rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (1 mg/kg) (for 33 days)
4serum creatinine levelLOU/MWslmale0.565mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (1 mg/kg) (for 47 days)109628rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (1 mg/kg) (for 47 days)
6serum creatinine levelLOU/MWslmale0.63845mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109629rat IgM immunocytoma cells (1 x 10E4 cells)
5serum creatinine levelLOU/MWslmale1.43058mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (2 mg/kg) (for 17 days)109630rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (2 mg/kg) (for 17 days)
5serum creatinine levelLOU/MWslmale0.63732mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109631rat IgM immunocytoma cells (1 x 10E4 cells)
5serum creatinine levelLOU/MWslmale0.53336mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 17 days)109632rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 17 days)
2serum creatinine levelLOU/MWslmale0.57065mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 33 days)109633rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 33 days)
6serum creatinine levelLOU/MWslmale0.5537mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109634rat IgM immunocytoma cells (1 x 10E4 cells)
6serum creatinine levelLOU/MWslmale0.56839mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 33 days)109635rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 33 days)
4serum creatinine levelLOU/MWslmale0.59664mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 47 days)109636rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 47 days)
6serum creatinine levelLOU/MWslmale0.62715mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109637rat IgM immunocytoma cells (1 x 10E4 cells)
5serum creatinine levelLOU/MWslmale0.55822mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (2 mg/kg) (for 17 days)109638rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (2 mg/kg) (for 17 days)
6serum creatinine levelLOU/MWslmale0.54805mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109639rat IgM immunocytoma cells (1 x 10E4 cells)
4serum creatinine levelLOU/MWslmale0.71416mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then positively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 17 days)109640rat IgM immunocytoma cells (1 x 10E4 cells) positively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 17 days)
6serum creatinine levelLOU/MWslmale0.60455mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109641rat IgM immunocytoma cells (1 x 10E4 cells)
3serum creatinine levelLOU/MWslmale0.64749mg/dlrat IgM immunocytoma cells (1 x 10E4 cells) then positively charged liposome-entrapped doxorubicin (1 mg/kg) (for 33 days)109642rat IgM immunocytoma cells (1 x 10E4 cells) positively charged liposome-entrapped doxorubicin (1 mg/kg) (for 33 days)
8serum albumin levelLOU/MWslmale312g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)109760rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)
5serum albumin levelLOU/MWslmale219g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then vehicle control condition (1 ml/kg) (for 7 days)109761rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)vehicle control condition (1 ml/kg) (for 7 days)
8serum albumin levelLOU/MWslmale316g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 ml/kg) 109762rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 ml/kg)
8serum albumin levelLOU/MWslmale298g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 ml/kg) (for 7 days)109763rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 ml/kg) (for 7 days)
8serum albumin levelLOU/MWslmale310g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 ml/kg) (for 14 days)109764rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 ml/kg) (for 14 days)
5serum albumin levelLOU/MWslmale237g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 ml/kg) (for 42 days)109765rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 ml/kg) (for 42 days)
3serum albumin levelLOU/MWslmale254g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 ml/kg) (for 56 days)109766rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 ml/kg) (for 56 days)
8serum albumin levelLOU/MWslmale336g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (1 ml/kg) 109767rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (1 ml/kg)
8serum albumin levelLOU/MWslmale289g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (1 ml/kg) (for 7 days)109768rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (1 ml/kg) (for 7 days)
8serum albumin levelLOU/MWslmale273g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (1 ml/kg) (for 14 days)109769rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (1 ml/kg) (for 14 days)
7serum albumin levelLOU/MWslmale62g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (1 ml/kg) (for 42 days)109770rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (1 ml/kg) (for 42 days)
8serum albumin levelLOU/MWslmale15g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (1 ml/kg) (for 56 days)109771rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (1 ml/kg) (for 56 days)
7serum albumin levelLOU/MWslmale249g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (2 ml/kg) 109772rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (2 ml/kg)
8serum albumin levelLOU/MWslmale269g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (2 ml/kg) (for 7 days)109773rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (2 ml/kg) (for 7 days)
8serum albumin levelLOU/MWslmale40g/dlrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (2 ml/kg) (for 14 days)109774rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (2 ml/kg) (for 14 days)
6serum albumin levelLOU/MWslmale299g/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109581rat IgM immunocytoma cells (1 x 10E4 cells)
6serum albumin levelLOU/MWslmale210g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then 0.9% sodium chloride solution (for 7 days)109582rat IgM immunocytoma cells (1 x 10E4 cells) 0.9% sodium chloride solution (for 7 days)
2serum albumin levelLOU/MWslmale195g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then 0.9% sodium chloride solution (for 10 days)109583rat IgM immunocytoma cells (1 x 10E4 cells) 0.9% sodium chloride solution (for 10 days)
6serum albumin levelLOU/MWslmale294g/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109584rat IgM immunocytoma cells (1 x 10E4 cells)
6serum albumin levelLOU/MWslmale317g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (0.5 mg/kg) (for 17 days)109585rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (0.5 mg/kg) (for 17 days)
6serum albumin levelLOU/MWslmale323g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (0.5 mg/kg) (for 25 days)109586rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (0.5 mg/kg) (for 25 days)
6serum albumin levelLOU/MWslmale224g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (0.5 mg/kg) (for 33 days)109587rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (0.5 mg/kg) (for 33 days)
2serum albumin levelLOU/MWslmale175g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (0.5 mg/kg) (for 40 days)109588rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (0.5 mg/kg) (for 40 days)
6serum albumin levelLOU/MWslmale278g/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109589rat IgM immunocytoma cells (1 x 10E4 cells)
6serum albumin levelLOU/MWslmale241g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (1 mg/kg) (for 17 days)109590rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (1 mg/kg) (for 17 days)
6serum albumin levelLOU/MWslmale201g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (1 mg/kg) (for 25 days)109591rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (1 mg/kg) (for 25 days)
6serum albumin levelLOU/MWslmale124g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (1 mg/kg) (for 40 days)109592rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (1 mg/kg) (for 40 days)
4serum albumin levelLOU/MWslmale96g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (1 mg/kg) (for 47 days)109593rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (1 mg/kg) (for 47 days)
6serum albumin levelLOU/MWslmale288g/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109594rat IgM immunocytoma cells (1 x 10E4 cells)
6serum albumin levelLOU/MWslmale245g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (2 mg/kg) (for 7 days)109595rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (2 mg/kg) (for 7 days)
6serum albumin levelLOU/MWslmale87g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (2 mg/kg) (for 10 days)109596rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (2 mg/kg) (for 10 days)
6serum albumin levelLOU/MWslmale289g/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109597rat IgM immunocytoma cells (1 x 10E4 cells)
5serum albumin levelLOU/MWslmale209g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposomes (for 7 days)109598rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposomes (for 7 days)
6serum albumin levelLOU/MWslmale208g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposomes (for 10 days)109599rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposomes (for 10 days)
5serum albumin levelLOU/MWslmale294g/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109600rat IgM immunocytoma cells (1 x 10E4 cells)
5serum albumin levelLOU/MWslmale302g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 17 days)109601rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 17 days)
5serum albumin levelLOU/MWslmale265g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 25 days)109602rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 25 days)
2serum albumin levelLOU/MWslmale205g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 33 days)109603rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 33 days)
6serum albumin levelLOU/MWslmale268g/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109604rat IgM immunocytoma cells (1 x 10E4 cells)
6serum albumin levelLOU/MWslmale301g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 17 days)109605rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 17 days)
6serum albumin levelLOU/MWslmale313g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 25 days)109606rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 25 days)
6serum albumin levelLOU/MWslmale285g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 33 days)109607rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 33 days)
5serum albumin levelLOU/MWslmale268g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 40 days)109608rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 40 days)
4serum albumin levelLOU/MWslmale265g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 47 days)109609rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 47 days)
6serum albumin levelLOU/MWslmale277g/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109610rat IgM immunocytoma cells (1 x 10E4 cells)
5serum albumin levelLOU/MWslmale277g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (2 mg/kg) (for 7 days)109611rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (2 mg/kg) (for 7 days)
5serum albumin levelLOU/MWslmale289g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (2 mg/kg) (for 10 days)109612rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (2 mg/kg) (for 10 days)
6serum albumin levelLOU/MWslmale280g/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109613rat IgM immunocytoma cells (1 x 10E4 cells)
6serum albumin levelLOU/MWslmale216g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then positively charged liposomes (for 7 days)109614rat IgM immunocytoma cells (1 x 10E4 cells) positively charged liposomes (for 7 days)
3serum albumin levelLOU/MWslmale207g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then positively charged liposomes (for 10 days)109615rat IgM immunocytoma cells (1 x 10E4 cells) positively charged liposomes (for 10 days)
6serum albumin levelLOU/MWslmale283g/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109616rat IgM immunocytoma cells (1 x 10E4 cells)
4serum albumin levelLOU/MWslmale194g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then positively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 17 days)109617rat IgM immunocytoma cells (1 x 10E4 cells) positively charged liposome-entrapped doxorubicin (0.5 mg/kg) (for 17 days)
6serum albumin levelLOU/MWslmale289g/dlrat IgM immunocytoma cells (1 x 10E4 cells) 109618rat IgM immunocytoma cells (1 x 10E4 cells)
6serum albumin levelLOU/MWslmale289g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then positively charged liposome-entrapped doxorubicin (1 mg/kg) (for 17 days)109619rat IgM immunocytoma cells (1 x 10E4 cells) positively charged liposome-entrapped doxorubicin (1 mg/kg) (for 17 days)
6serum albumin levelLOU/MWslmale244g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then positively charged liposome-entrapped doxorubicin (1 mg/kg) (for 25 days)109620rat IgM immunocytoma cells (1 x 10E4 cells) positively charged liposome-entrapped doxorubicin (1 mg/kg) (for 25 days)
3serum albumin levelLOU/MWslmale175g/dlrat IgM immunocytoma cells (1 x 10E4 cells) then positively charged liposome-entrapped doxorubicin (1 mg/kg) (for 33 days)109621rat IgM immunocytoma cells (1 x 10E4 cells) positively charged liposome-entrapped doxorubicin (1 mg/kg) (for 33 days)
N/Amaximum tumor size decrease to pretreatment tumor size ratioLOU/Mboth100%rat IgM immunocytoma cells (1 x 10E4 cells) then cisplatin (1 mg/kg) (for 21 days)109481rat IgM immunocytoma cells (1 x 10E4 cells) cisplatin (1 mg/kg) (for 21 days)
N/Amaximum tumor size decrease to pretreatment tumor size ratioLOU/Mboth90.8%rat IgM immunocytoma cells (1 x 10E4 cells) then spiroplatin (1 mg/kg) (for 21 days)109482rat IgM immunocytoma cells (1 x 10E4 cells) spiroplatin (1 mg/kg) (for 21 days)
N/Amaximum tumor size decrease to pretreatment tumor size ratioLOU/Mboth78.5%rat IgM immunocytoma cells (1 x 10E4 cells) then spiroplatin (2 mg/kg) (for 21 days)109483rat IgM immunocytoma cells (1 x 10E4 cells) spiroplatin (2 mg/kg) (for 21 days)
N/Amaximum tumor size decrease to pretreatment tumor size ratioLOU/Mboth29.3%rat IgM immunocytoma cells (1 x 10E4 cells) then cisplatin (0.25 mg/kg) (for 21 days)109487rat IgM immunocytoma cells (1 x 10E4 cells) cisplatin (0.25 mg/kg) (for 21 days)
N/Amaximum tumor size decrease to pretreatment tumor size ratioLOU/Mboth66.7%rat IgM immunocytoma cells (1 x 10E4 cells) then cisplatin (0.5 mg/kg) (for 21 days)109488rat IgM immunocytoma cells (1 x 10E4 cells) cisplatin (0.5 mg/kg) (for 21 days)
N/Amaximum tumor size decrease to pretreatment tumor size ratioLOU/Mboth89.8%rat IgM immunocytoma cells (1 x 10E4 cells) then cisplatin (1 mg/kg) (for 21 days)109489rat IgM immunocytoma cells (1 x 10E4 cells) cisplatin (1 mg/kg) (for 21 days)
N/Amaximum tumor size decrease to pretreatment tumor size ratioLOU/Mboth-2.5%rat IgM immunocytoma cells (1 x 10E4 cells) then spiroplatin (0.25 mg/kg) (for 21 days)109490rat IgM immunocytoma cells (1 x 10E4 cells) spiroplatin (0.25 mg/kg) (for 21 days)
N/Amaximum tumor size decrease to pretreatment tumor size ratioLOU/Mboth63.6%rat IgM immunocytoma cells (1 x 10E4 cells) then spiroplatin (0.5 mg/kg) (for 21 days)109491rat IgM immunocytoma cells (1 x 10E4 cells) spiroplatin (0.5 mg/kg) (for 21 days)
N/Amaximum tumor size decrease to pretreatment tumor size ratioLOU/Mboth95.8%rat IgM immunocytoma cells (1 x 10E4 cells) then spiroplatin (1 mg/kg) (for 21 days)109492rat IgM immunocytoma cells (1 x 10E4 cells) spiroplatin (1 mg/kg) (for 21 days)
N/Atime from therapy-induced maximal immunocytoma size decrease to regrowth of tumor to a diameter of 10 mmLOU/Mboth4.6drat IgM immunocytoma cells (1 x 10E4 cells) then cisplatin (0.5 mg/kg) (for 7 days)109497rat IgM immunocytoma cells (1 x 10E4 cells) cisplatin (0.5 mg/kg) (for 7 days)
N/Atime from therapy-induced maximal immunocytoma size decrease to regrowth of tumor to a diameter of 10 mmLOU/Mboth8.6drat IgM immunocytoma cells (1 x 10E4 cells) then cisplatin (1 mg/kg) (for 7 days)109498rat IgM immunocytoma cells (1 x 10E4 cells) cisplatin (1 mg/kg) (for 7 days)
N/Atime from therapy-induced maximal immunocytoma size decrease to regrowth of tumor to a diameter of 10 mmLOU/Mboth6.8drat IgM immunocytoma cells (1 x 10E4 cells) then spiroplatin (0.5 mg/kg) (for 7 days)109499rat IgM immunocytoma cells (1 x 10E4 cells) spiroplatin (0.5 mg/kg) (for 7 days)
N/Atime from therapy-induced maximal immunocytoma size decrease to regrowth of tumor to a diameter of 10 mmLOU/Mboth7.2drat IgM immunocytoma cells (1 x 10E4 cells) then spiroplatin (1 mg/kg) (for 7 days)109500rat IgM immunocytoma cells (1 x 10E4 cells) spiroplatin (1 mg/kg) (for 7 days)
N/Atime from start of drug therapy to immunocytoma regrowthLOU/Mboth35drat IgM immunocytoma cells (1 x 10E4 cells) then cisplatin (1 mg/kg) (for 35 days)109484rat IgM immunocytoma cells (1 x 10E4 cells) cisplatin (1 mg/kg) (for 35 days)
N/Atime from start of drug therapy to immunocytoma regrowthLOU/Mboth28drat IgM immunocytoma cells (1 x 10E4 cells) then spiroplatin (1 mg/kg) (for 28 days)109485rat IgM immunocytoma cells (1 x 10E4 cells) spiroplatin (1 mg/kg) (for 28 days)
N/Atime from start of drug therapy to immunocytoma regrowthLOU/Mboth26.1drat IgM immunocytoma cells (1 x 10E4 cells) then spiroplatin (2 mg/kg) (for 28 days)109486rat IgM immunocytoma cells (1 x 10E4 cells) spiroplatin (2 mg/kg) (for 28 days)
N/Atime from start of drug therapy to immunocytoma regrowthLOU/Mboth19.2drat IgM immunocytoma cells (1 x 10E4 cells) then cisplatin (0.5 mg/kg) (for 21 days)109493rat IgM immunocytoma cells (1 x 10E4 cells) cisplatin (0.5 mg/kg) (for 21 days)
N/Atime from start of drug therapy to immunocytoma regrowthLOU/Mboth21.6drat IgM immunocytoma cells (1 x 10E4 cells) then cisplatin (1 mg/kg) (for 21 days)109494rat IgM immunocytoma cells (1 x 10E4 cells) cisplatin (1 mg/kg) (for 21 days)
N/Atime from start of drug therapy to immunocytoma regrowthLOU/Mboth19.4drat IgM immunocytoma cells (1 x 10E4 cells) then spiroplatin (0.5 mg/kg) (for 21 days)109495rat IgM immunocytoma cells (1 x 10E4 cells) spiroplatin (0.5 mg/kg) (for 21 days)
N/Atime from start of drug therapy to immunocytoma regrowthLOU/Mboth20.2drat IgM immunocytoma cells (1 x 10E4 cells) then spiroplatin (1 mg/kg) (for 21 days)109496rat IgM immunocytoma cells (1 x 10E4 cells) spiroplatin (1 mg/kg) (for 21 days)
6change in body weight to initial body weight ratioLOU/MWslmale-8.1%rat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (1 mg/kg) (for 10 days)109575rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (1 mg/kg) (for 10 days)
6change in body weight to initial body weight ratioLOU/MWslmale-4.1%rat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 10 days)109576rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 10 days)
6change in body weight to initial body weight ratioLOU/MWslmale-3.2%rat IgM immunocytoma cells (1 x 10E4 cells) then positively charged liposome-entrapped doxorubicin (1 mg/kg) (for 10 days)109577rat IgM immunocytoma cells (1 x 10E4 cells) positively charged liposome-entrapped doxorubicin (1 mg/kg) (for 10 days)
6change in body weight to initial body weight ratioLOU/MWslmale10%rat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 28 days)109578rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (1 mg/kg) (for 28 days)
6change in body weight to initial body weight ratioLOU/MWslmale-40%rat IgM immunocytoma cells (1 x 10E4 cells) then doxorubicin (2 mg/kg) (for 14 days)109579rat IgM immunocytoma cells (1 x 10E4 cells) doxorubicin (2 mg/kg) (for 14 days)
6change in body weight to initial body weight ratioLOU/MWslmale-10%rat IgM immunocytoma cells (1 x 10E4 cells) then negatively charged liposome-entrapped doxorubicin (2 mg/kg) (for 14 days)109580rat IgM immunocytoma cells (1 x 10E4 cells) negatively charged liposome-entrapped doxorubicin (2 mg/kg) (for 14 days)
8subcutaneous tumor diameter measurementLOU/MWslmale15.8mmrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)109744rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)
8subcutaneous tumor diameter measurementLOU/MWslmale37.2mmrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then vehicle control condition (1 ml/kg) (for 28 days)109745rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)vehicle control condition (1 ml/kg) (for 28 days)
8subcutaneous tumor diameter measurementLOU/MWslmale37.2mmrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.06 mg/kg) (for 32 days)109746rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.06 mg/kg) (for 32 days)
8subcutaneous tumor diameter measurementLOU/MWslmale36.9mmrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.12 mg/kg) (for 32 days)109747rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.12 mg/kg) (for 32 days)
8subcutaneous tumor diameter measurementLOU/MWslmale32.6mmrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.25 mg/kg) (for 32 days)109748rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.25 mg/kg) (for 32 days)
8subcutaneous tumor diameter measurementLOU/MWslmale5mmrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 mg/kg) (for 39 days)109749rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 mg/kg) (for 39 days)
2subcutaneous tumor diameter measurementLOU/MWslmale0mmrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (0.5 mg/kg) (between 7.3 and 175 days)109750rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (0.5 mg/kg) (between 7.3 and 175 days)
8subcutaneous tumor diameter measurementLOU/MWslmale7.6mmrat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days) then doxorubicin (2 mg/kg) (for 32 days)109751rat IgM immunocytoma cells (0.01 x 10E6 cells) (for 18 days)doxorubicin (2 mg/kg) (for 32 days)
84subcutaneous tumor diameter measurementLOU/MWslmale18.1mmrat IgM immunocytoma cells (1 x 10E4 cells) 109570rat IgM immunocytoma cells (1 x 10E4 cells)
30subcutaneous tumor diameter measurementLOU/MWslmale20mmrat IgM immunocytoma cells (1 x 10E4 cells) 109571rat IgM immunocytoma cells (1 x 10E4 cells)
9post-treatment survival time from doxorubicin-treated IgM immunocytomaLOU/MWslmale8drat IgM immunocytoma cells (1 x 10E4 cells) (between 17 and 21 days) then 0.9% sodium chloride solution109572rat IgM immunocytoma cells (1 x 10E4 cells) (between 17 and 21 days)0.9% sodium chloride solution
10post-treatment survival time from doxorubicin-treated IgM immunocytomaLOU/MWslmale23drat IgM immunocytoma cells (1 x 10E4 cells) (between 17 and 21 days) then doxorubicin (2 mg/kg) 109573rat IgM immunocytoma cells (1 x 10E4 cells) (between 17 and 21 days)doxorubicin (2 mg/kg)
10post-treatment survival time from doxorubicin-treated IgM immunocytomaLOU/MWslmale40drat IgM immunocytoma cells (1 x 10E4 cells) (between 17 and 21 days) then negatively charged liposome-entrapped doxorubicin (2 mg/kg) 109574rat IgM immunocytoma cells (1 x 10E4 cells) (between 17 and 21 days)negatively charged liposome-entrapped doxorubicin (2 mg/kg)