RCS/N |
photopic B wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled visible light condition (30 cd/m2) (for 0.1 hours) then visible light stimulus (10 cd x s/m2) and controlled visible light condition (30 cd/m2) |
Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. |
cone electrophysiology trait |
not specified |
242 days
| 4 |
30.0 |
uV |
5.5 |
11.0 |
electroretinography |
cornea |
0.0 |
AAV8 injection |
240 |
days |
treated eye |
photopic b-wave amplitude ERG |
108685 |
3129 |
Hsd:SD |
scotopic A wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (4 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) |
Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. |
rod electrophysiology trait |
both |
0 days
| 9 |
154.0 |
uV |
|
|
electroretinography |
cornea |
0.0 |
subretinal injection |
30 |
days |
|
scotopic a-wave ERG |
108648 |
3128 |
RCS/N |
scotopic A wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) |
Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. |
rod electrophysiology trait |
not specified |
62 days
| 6 |
175.0 |
uV |
14.7 |
36.0 |
electroretinography |
cornea |
0.0 |
AAV8 injection |
60 |
days |
treated eye |
scotopic a-wave amplitude ERG |
108680 |
3129 |
RCS/N |
scotopic B wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.01 cd x s/m2) |
Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. |
rod electrophysiology trait |
not specified |
242 days
| 4 |
223.0 |
uV |
28.0 |
56.0 |
electroretinography |
cornea |
0.0 |
AAV8 injection |
240 |
days |
treated eye |
scotopic b-wave amplitude ERG |
108684 |
3129 |
Hsd:SD |
photopic B wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (40 x 10E8 vg) then controlled visible light condition (30 cd x s/m2) then visible light stimulus (12 cd/m2) |
Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. |
cone electrophysiology trait |
both |
0 days
| 9 |
57.0 |
uV |
|
|
electroretinography |
cornea |
0.0 |
subretinal injection |
30 |
days |
|
photopic b-wave ERG |
108656 |
3128 |
Hsd:SD |
photopic B wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (4 x 10E8 vg) then controlled visible light condition (30 cd x s/m2) then visible light stimulus (12 cd/m2) |
Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. |
cone electrophysiology trait |
both |
0 days
| 9 |
59.0 |
uV |
|
|
electroretinography |
cornea |
0.0 |
subretinal injection |
30 |
days |
|
photopic b-wave ERG |
108650 |
3128 |
RCS/LavRrrc |
b-wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (40 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd/m2) |
Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. |
eye electrophysiology trait |
both |
0 days
| 5 |
137.0 |
uV |
18.0 |
40.25 |
electroretinography |
cornea |
0.0 |
subretinal injection |
60 |
days |
|
scotopic b-wave ERG |
108664 |
3128 |
Hsd:SD |
scotopic B wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (40 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) |
Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. |
rod electrophysiology trait |
both |
0 days
| 9 |
397.0 |
uV |
|
|
electroretinography |
cornea |
0.0 |
subretinal injection |
30 |
days |
|
scotopic b-wave ERG |
108652 |
3128 |
Hsd:SD |
scotopic A wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (40 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) |
Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. |
rod electrophysiology trait |
both |
0 days
| 9 |
173.0 |
uV |
|
|
electroretinography |
cornea |
0.0 |
subretinal injection |
30 |
days |
|
scotopic a-wave ERG |
108654 |
3128 |
RCS/N |
scotopic B wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) |
Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. |
rod electrophysiology trait |
not specified |
62 days
| 6 |
500.0 |
uV |
61.24 |
150.0 |
electroretinography |
cornea |
0.0 |
AAV8 injection |
60 |
days |
treated eye |
scotopic b-wave amplitude ERG |
108682 |
3129 |
Hsd:SD |
scotopic B wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (4 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) |
Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. |
rod electrophysiology trait |
both |
0 days
| 9 |
387.0 |
uV |
|
|
electroretinography |
cornea |
0.0 |
subretinal injection |
30 |
days |
|
scotopic b-wave ERG |
108646 |
3128 |