| Hsd:SD |
thymus weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
thymus mass |
female |
84 days
| 10 |
1.29 |
mg/g |
0.23 |
0.73 |
post excision weight measurement |
|
0 |
105890 |
3021 |
| Hsd:SD |
thymus weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
thymus mass |
female |
84 days
| 10 |
1.03 |
mg/g |
0.19 |
0.6 |
post excision weight measurement |
|
0 |
105892 |
3021 |
| Hsd:SD |
brain weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
brain mass |
female |
84 days
| 10 |
0.76 |
% |
0.03 |
0.09 |
post excision weight measurement |
|
0 |
105910 |
3021 |
| Hsd:SD |
brain weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
brain mass |
female |
84 days
| 10 |
0.76 |
% |
0.06 |
0.18 |
post excision weight measurement |
|
0 |
105916 |
3021 |
| Hsd:SD |
both ovaries weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
ovary mass |
female |
84 days
| 10 |
0.05 |
% |
0.01 |
0.04 |
post excision weight measurement |
|
0 |
105924 |
3021 |
| Hsd:SD |
blood hemoglobin level |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
14.59 |
g/dl |
0.61 |
1.93 |
automated hematology analysis |
|
0 |
105950 |
3021 |
| Hsd:SD |
hematocrit |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
44.79 |
% |
2.21 |
6.99 |
automated hematology analysis |
|
0 |
105964 |
3021 |
| Hsd:SD |
mean corpuscular volume |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
52.98 |
fl |
1.49 |
4.71 |
automated hematology analysis |
|
0 |
105978 |
3021 |
| Hsd:SD |
white blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
10.54 |
x 1000 cells/ul |
1.42 |
4.49 |
automated hematology analysis |
|
0 |
106024 |
3021 |
| Hsd:SD |
blood neutrophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.16 |
x 1000 cells/ul |
0.26 |
0.82 |
automated hematology analysis |
|
0 |
106034 |
3021 |
| Hsd:SD |
blood neutrophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.62 |
x 1000 cells/ul |
1.38 |
4.36 |
automated hematology analysis |
|
0 |
106036 |
3021 |
| Hsd:SD |
blood monocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.33 |
x 1000 cells/ul |
0.08 |
0.25 |
automated hematology analysis |
|
0 |
106054 |
3021 |
| Hsd:SD |
blood eosinophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.16 |
x 1000 cells/ul |
0.21 |
0.66 |
automated hematology analysis |
|
0 |
106066 |
3021 |
| Hsd:SD |
blood eosinophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.08 |
x 1000 cells/ul |
0.02 |
0.06 |
automated hematology analysis |
|
0 |
106068 |
3021 |
| Hsd:SD |
blood eosinophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.04 |
x 1000 cells/ul |
0.01 |
0.03 |
automated hematology analysis |
|
0 |
106072 |
3021 |
| Hsd:SD |
blood eosinophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.04 |
x 1000 cells/ul |
0.06 |
0.19 |
automated hematology analysis |
|
0 |
106074 |
3021 |
| Hsd:SD |
liver weight as percentage of body weight |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84 days
| 10 |
5.03 |
% |
0.37 |
1.17 |
post excision weight measurement |
0.0 |
0 |
105724 |
3021 |
| Hsd:SD |
both ovaries weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
ovary mass |
female |
84 days
| 10 |
0.04 |
% |
0.01 |
0.02 |
post excision weight measurement |
|
0 |
105926 |
3021 |
| Hsd:SD |
blood hemoglobin level |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
15.76 |
g/dl |
0.88 |
2.78 |
automated hematology analysis |
|
0 |
105954 |
3021 |
| Hsd:SD |
white blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
9.63 |
x 1000 cells/ul |
1.4 |
4.43 |
automated hematology analysis |
|
0 |
106020 |
3021 |
| Hsd:SD |
blood basophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.1 |
x 1000 cells/ul |
0.03 |
0.09 |
automated hematology analysis |
|
0 |
106084 |
3021 |
| Hsd:SD |
thymus weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
thymus mass |
female |
84 days
| 10 |
1.47 |
mg/g |
0.24 |
0.76 |
post excision weight measurement |
|
0 |
105886 |
3021 |
| Hsd:SD |
spleen weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
spleen mass |
female |
84 days
| 10 |
0.28 |
% |
0.03 |
0.09 |
post excision weight measurement |
|
0 |
105900 |
3021 |
| Hsd:SD |
white blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
10.39 |
x 1000 cells/ul |
2.08 |
6.58 |
automated hematology analysis |
|
0 |
106018 |
3021 |
| Hsd:SD |
blood neutrophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.08 |
x 1000 cells/ul |
0.47 |
1.49 |
automated hematology analysis |
|
0 |
106038 |
3021 |
| Hsd:SD |
blood lymphocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
7.73 |
x 1000 cells/ul |
1.37 |
4.33 |
automated hematology analysis |
|
0 |
106044 |
3021 |
| Hsd:SD |
blood eosinophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.07 |
x 1000 cells/ul |
0.02 |
0.06 |
automated hematology analysis |
|
0 |
106070 |
3021 |
| Hsd:SD |
blood basophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.08 |
x 1000 cells/ul |
0.03 |
0.09 |
automated hematology analysis |
|
0 |
106078 |
3021 |
| Hsd:SD |
blood basophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.08 |
x 1000 cells/ul |
0.03 |
0.09 |
automated hematology analysis |
|
0 |
106086 |
3021 |
| Hsd:SD |
red blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
9.17 |
x 10E6 cells/ul |
0.65 |
2.06 |
automated hematology analysis |
|
0 |
105942 |
3021 |
| Hsd:SD |
blood hemoglobin level |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
14.27 |
g/dl |
0.64 |
2.02 |
automated hematology analysis |
|
0 |
105948 |
3021 |
| Hsd:SD |
mean corpuscular volume |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
58.08 |
fl |
1.07 |
3.38 |
automated hematology analysis |
|
0 |
105970 |
3021 |
| Hsd:SD |
mean corpuscular volume |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
54.57 |
fl |
0.91 |
2.88 |
automated hematology analysis |
|
0 |
105976 |
3021 |
| Hsd:SD |
mean corpuscular hemoglobin |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
18.19 |
pg |
0.55 |
1.74 |
automated hematology analysis |
|
0 |
105986 |
3021 |
| Hsd:SD |
liver weight as percentage of body weight |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84 days
| 10 |
4.16 |
% |
0.21 |
0.65 |
post excision weight measurement |
0.0 |
0 |
105722 |
3021 |
| Hsd:SD |
liver weight as percentage of body weight |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84 days
| 10 |
4.69 |
% |
0.34 |
1.06 |
post excision weight measurement |
0.0 |
0 |
105723 |
3021 |
| Hsd:SD |
spleen weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
spleen mass |
female |
84 days
| 10 |
0.28 |
% |
0.03 |
0.09 |
post excision weight measurement |
|
0 |
105902 |
3021 |
| Hsd:SD |
both ovaries weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
ovary mass |
female |
84 days
| 10 |
0.05 |
% |
0.01 |
0.03 |
post excision weight measurement |
|
0 |
105922 |
3021 |
| Hsd:SD |
both ovaries weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
ovary mass |
female |
84 days
| 10 |
0.04 |
% |
0.01 |
0.03 |
post excision weight measurement |
|
0 |
105930 |
3021 |
| Hsd:SD |
red blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
8.21 |
x 10E6 cells/ul |
0.32 |
1.01 |
automated hematology analysis |
|
0 |
105940 |
3021 |
| Hsd:SD |
blood hemoglobin level |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
14.68 |
g/dl |
0.58 |
1.83 |
automated hematology analysis |
|
0 |
105952 |
3021 |
| Hsd:SD |
hematocrit |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
44.34 |
% |
1.82 |
5.76 |
automated hematology analysis |
|
0 |
105958 |
3021 |
| Hsd:SD |
hematocrit |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
45.1 |
% |
2.05 |
6.48 |
automated hematology analysis |
|
0 |
105962 |
3021 |
| Hsd:SD |
mean corpuscular volume |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
57.82 |
fl |
1.25 |
3.95 |
automated hematology analysis |
|
0 |
105972 |
3021 |
| Hsd:SD |
mean corpuscular volume |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
56.27 |
fl |
1.81 |
5.72 |
automated hematology analysis |
|
0 |
105974 |
3021 |
| Hsd:SD |
mean corpuscular hemoglobin concentration |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.17 |
g/dl |
0.95 |
3.0 |
automated hematology analysis |
|
0 |
105996 |
3021 |
| Hsd:SD |
mean corpuscular hemoglobin concentration |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.37 |
g/dl |
0.52 |
1.64 |
automated hematology analysis |
|
0 |
105998 |
3021 |
| Hsd:SD |
mean corpuscular hemoglobin concentration |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.51 |
g/dl |
1.05 |
3.32 |
automated hematology analysis |
|
0 |
106002 |
3021 |
| Hsd:SD |
platelet count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1291.9 |
x 1000 cells/ul |
200.69 |
634.64 |
automated hematology analysis |
|
0 |
106006 |
3021 |
| Hsd:SD |
spleen weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
spleen mass |
female |
84 days
| 10 |
0.29 |
% |
0.02 |
0.07 |
post excision weight measurement |
|
0 |
105898 |
3021 |
| Hsd:SD |
brain weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
brain mass |
female |
84 days
| 10 |
0.84 |
% |
0.05 |
0.16 |
post excision weight measurement |
|
0 |
105918 |
3021 |
| Hsd:SD |
blood monocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.27 |
x 1000 cells/ul |
0.05 |
0.16 |
automated hematology analysis |
|
0 |
106058 |
3021 |
| Hsd:SD |
blood basophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.08 |
x 1000 cells/ul |
0.04 |
0.13 |
automated hematology analysis |
|
0 |
106080 |
3021 |
| Hsd:SD |
blood basophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.08 |
x 1000 cells/ul |
0.03 |
0.09 |
automated hematology analysis |
|
0 |
106082 |
3021 |
| Hsd:SD |
brain weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
brain mass |
female |
84 days
| 10 |
0.77 |
% |
0.05 |
0.15 |
post excision weight measurement |
|
0 |
105914 |
3021 |
| Hsd:SD |
red blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
7.63 |
x 10E6 cells/ul |
0.23 |
0.73 |
automated hematology analysis |
|
0 |
105934 |
3021 |
| Hsd:SD |
platelet count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1160.6 |
x 1000 cells/ul |
192.03 |
607.25 |
automated hematology analysis |
|
0 |
106012 |
3021 |
| Hsd:SD |
blood neutrophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.38 |
x 1000 cells/ul |
0.33 |
1.04 |
automated hematology analysis |
|
0 |
106032 |
3021 |
| Hsd:SD |
spleen weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
spleen mass |
female |
84 days
| 10 |
0.28 |
% |
0.02 |
0.07 |
post excision weight measurement |
|
0 |
105904 |
3021 |
| Hsd:SD |
brain weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
brain mass |
female |
84 days
| 10 |
0.75 |
% |
0.06 |
0.18 |
post excision weight measurement |
|
0 |
105912 |
3021 |
| Hsd:SD |
liver weight as percentage of body weight |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84 days
| 10 |
3.65 |
% |
0.16 |
0.51 |
post excision weight measurement |
0.0 |
0 |
105721 |
3021 |
| Hsd:SD |
platelet count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1299.4 |
x 1000 cells/ul |
168.51 |
532.88 |
automated hematology analysis |
|
0 |
106008 |
3021 |
| Hsd:SD |
platelet count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
870.2 |
x 1000 cells/ul |
189.09 |
597.96 |
automated hematology analysis |
|
0 |
106014 |
3021 |
| Hsd:SD |
white blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
9.64 |
x 1000 cells/ul |
1.27 |
4.02 |
automated hematology analysis |
|
0 |
106022 |
3021 |
| Hsd:SD |
blood neutrophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.86 |
x 1000 cells/ul |
1.0 |
3.16 |
automated hematology analysis |
|
0 |
106030 |
3021 |
| Hsd:SD |
blood lymphocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
8.36 |
x 1000 cells/ul |
1.92 |
6.07 |
automated hematology analysis |
|
0 |
106048 |
3021 |
| Hsd:SD |
blood lymphocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
7.18 |
x 1000 cells/ul |
1.78 |
5.63 |
automated hematology analysis |
|
0 |
106050 |
3021 |
| Hsd:SD |
blood monocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.32 |
x 1000 cells/ul |
0.12 |
0.38 |
automated hematology analysis |
|
0 |
106060 |
3021 |
| Hsd:SD |
red blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
8.02 |
x 10E6 cells/ul |
0.26 |
0.82 |
automated hematology analysis |
|
0 |
105938 |
3021 |
| Hsd:SD |
mean corpuscular hemoglobin |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
18.61 |
pg |
0.78 |
2.47 |
automated hematology analysis |
|
0 |
105984 |
3021 |
| Hsd:SD |
mean corpuscular hemoglobin |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
17.89 |
pg |
0.31 |
0.98 |
automated hematology analysis |
|
0 |
105988 |
3021 |
| Hsd:SD |
hematocrit |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
44.42 |
% |
1.74 |
5.5 |
automated hematology analysis |
|
0 |
105960 |
3021 |
| Hsd:SD |
thymus weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
thymus mass |
female |
84 days
| 10 |
1.49 |
mg/g |
0.27 |
0.85 |
post excision weight measurement |
|
0 |
105888 |
3021 |
| Hsd:SD |
spleen weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
spleen mass |
female |
84 days
| 10 |
0.27 |
% |
0.02 |
0.05 |
post excision weight measurement |
|
0 |
105906 |
3021 |
| Hsd:SD |
platelet count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1280.89 |
x 1000 cells/ul |
252.44 |
798.29 |
automated hematology analysis |
|
0 |
106010 |
3021 |
| Hsd:SD |
white blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
8.73 |
x 1000 cells/ul |
2.08 |
6.58 |
automated hematology analysis |
|
0 |
106026 |
3021 |
| Hsd:SD |
blood lymphocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
7.88 |
x 1000 cells/ul |
1.29 |
4.08 |
automated hematology analysis |
|
0 |
106042 |
3021 |
| Hsd:SD |
blood lymphocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
7.97 |
x 1000 cells/ul |
1.13 |
3.57 |
automated hematology analysis |
|
0 |
106046 |
3021 |
| Hsd:SD |
blood monocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.29 |
x 1000 cells/ul |
0.06 |
0.19 |
automated hematology analysis |
|
0 |
106056 |
3021 |
| Hsd:SD |
blood monocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.24 |
x 1000 cells/ul |
0.09 |
0.28 |
automated hematology analysis |
|
0 |
106062 |
3021 |
| Hsd:SD |
both ovaries weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
ovary mass |
female |
84 days
| 10 |
0.04 |
% |
0.01 |
0.04 |
post excision weight measurement |
|
0 |
105928 |
3021 |
| Hsd:SD |
red blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
7.68 |
x 10E6 cells/ul |
0.34 |
1.08 |
automated hematology analysis |
|
0 |
105936 |
3021 |
| Hsd:SD |
blood hemoglobin level |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
14.3 |
g/dl |
0.54 |
1.71 |
automated hematology analysis |
|
0 |
105946 |
3021 |
| Hsd:SD |
hematocrit |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
48.55 |
% |
3.28 |
10.37 |
automated hematology analysis |
|
0 |
105966 |
3021 |
| Hsd:SD |
mean corpuscular hemoglobin |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
18.71 |
pg |
0.44 |
1.39 |
automated hematology analysis |
|
0 |
105982 |
3021 |
| Hsd:SD |
mean corpuscular hemoglobin |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
17.22 |
pg |
0.59 |
1.87 |
automated hematology analysis |
|
0 |
105990 |
3021 |
| Hsd:SD |
mean corpuscular hemoglobin concentration |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.23 |
g/dl |
0.64 |
2.02 |
automated hematology analysis |
|
0 |
105994 |
3021 |
| Hsd:SD |
mean corpuscular hemoglobin concentration |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.81 |
g/dl |
0.79 |
2.5 |
automated hematology analysis |
|
0 |
106000 |
3021 |
| Hsd:SD |
thymus weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
thymus mass |
female |
84 days
| 10 |
0.65 |
mg/g |
0.18 |
0.57 |
post excision weight measurement |
|
0 |
105894 |
3021 |
