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Strain
Phenotype
Conditions
Study
Experiment Name
Sex
Age
# of Animals
Value
Units
SEM
SD
Method
Method Duration
Post Insult Type
Post Insult Time Value
Post Insult Time Unit
Record ID
Study ID
SHR/NCrlCrlj
plasma renin activity level
unilateral nephrectomy (for 42 days) then controlled hydralazine content drinking water (15 mg/kg/d) (for 28 days)
Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9.
renin activity
male
126.0 days
5
5.5
ng/ml/h
1.7
3.8
radioimmunoassay
0.0
unx
42
days
101265
2583
SHR/N-cp
plasma renin activity level
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then controlled hydralazine content drinking water (30 mg/l) (between 84 and 98 days) and hydralazine (50 mg/l) (between 84 and 98 days) and reserpine (4 mg/l) (between 84 and 98 days)
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7.
renin activity
male
140.0 days-168.0 days
8
38.0
ng/ml/h
2.0
5.66
radioimmunoassay
0.0
101534
2601
MW
plasma renin activity level
nephrectomy (for 28 days) then reserpine (5 mg/l) (for 21 days) and hydralazine (80 mg/l) (for 21 days) and controlled hydralazine content drinking water (25 mg/l) (for 21 days)
Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000.
renin activity
male
days
7
21.9
ng/ml/h
2.5
6.61
radioimmunoassay
0.0
5/6 nephrectomy
28
days
101046
2561