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# of Animals	Phenotype	Strain	Sex	Value	Units	Conditions	Record ID	Condition 1	Condition 2	Condition 3
8	skin sodium level to skin dry weight ratio	WKY/NHsd	male	0.112	REQUEST NEW VALUE	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99132	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin sodium level to skin dry weight ratio	WKY/NHsd	male	0.164	REQUEST NEW VALUE	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99134	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin chloride level to skin dry weight ratio	WKY/NHsd	male	0.052	mmol/g	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99136	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin chloride level to skin dry weight ratio	WKY/NHsd	male	0.073	mmol/g	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99138	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
7	skin water level to skin dry weight ratio	WKY/NHsd	male	1.223	ml/g	standard rat chow (for 8 days) then sunitinib (0.5 ml) (for 8 days)	99139	standard rat chow (for 8 days)	sunitinib (0.5 ml) (for 8 days)
8	skin water level to skin dry weight ratio	WKY/NHsd	male	1.208	ml/g	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99140	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin water level to skin dry weight ratio	WKY/NHsd	male	1.522	ml/g	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99142	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin potassium level plus skin sodium level to skin water level ratio	WKY/NHsd	male	0.167		standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99144	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin potassium level plus skin sodium level to skin water level ratio	WKY/NHsd	male	0.171		controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99146	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin chloride level to skin water level ratio	WKY/NHsd	male	92	mmol/l	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99148	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin chloride level to skin water level ratio	WKY/NHsd	male	108	mmol/l	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99150	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin chloride level to skin water level ratio	WKY/NHsd	male	43	mmol/l	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99152	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin chloride level to skin water level ratio	WKY/NHsd	male	50	mmol/l	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99154	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin potassium level to skin water level ratio	WKY/NHsd	male	75	mmol/l	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99156	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	skin potassium level to skin water level ratio	WKY/NHsd	male	69	mmol/l	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99158	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	plasma sodium level	WKY/NHsd	male	137.8	mmol/l	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99160	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	plasma sodium level	WKY/NHsd	male	139.4	mmol/l	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99162	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	plasma potassium level	WKY/NHsd	male	4.2	mmol/l	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99164	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	plasma potassium level	WKY/NHsd	male	4.4	mmol/l	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99166	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	plasma chloride level	WKY/NHsd	male	100.5	mmol/l	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99168	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	plasma chloride level	WKY/NHsd	male	109.1	mmol/l	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99170	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	plasma creatinine level	WKY/NHsd	male	0.35180942	mg/dl	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99172	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	plasma creatinine level	WKY/NHsd	male	0.31787282	mg/dl	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99174	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	plasma cystatin C level	WKY/NHsd	male	4.7	mg/l	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99176	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	plasma cystatin C level	WKY/NHsd	male	3.9	mg/l	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99178	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	creatinine clearance	WKY/NHsd	male	3.1	ml/min	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99180	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	creatinine clearance	WKY/NHsd	male	3.5	ml/min	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99182	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	urine sodium excretion rate	WKY/NHsd	male	1.1	mEq/d	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99184	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	urine sodium excretion rate	WKY/NHsd	male	34.3	mEq/d	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99186	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	mean arterial blood pressure	WKY/NHsd	male	128	mmHg	standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99188	standard rat chow (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)
8	mean arterial blood pressure	WKY/NHsd	male	124	mmHg	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	99190	controlled sodium content diet (8 %) (for 8 days)	0.9% sodium chloride solution (0.9 %) (for 8 days)	sunitinib (7 mg/kg/d) (for 8 days)

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.
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