Phenominer Database Results (62 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Record ID Study ID
Hsd:WI plasma uric acid level cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood uric acid amount male  days 8 7.67 mg/dl 0.55 1.55 liquid phase colorimetry 0.0 75949 1542
Hsd:WI plasma uric acid level cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood uric acid amount male  days 8 4.89 mg/dl 0.35 0.98 liquid phase colorimetry 0.0 75950 1542
Hsd:WI plasma urea nitrogen level lactotransferrin (300 mg/kg/d) (for 6 days) then cisplatin (7 mg/kg) Kimoto Y, et al., J Vet Med Sci. 2013 Feb;75(2):159-64. Epub 2012 Oct 10. blood urea nitrogen amount male 53.0 days 6 6.52 mmol/l 0.59 1.45 plasma urea nitrogen analysis 0.0 76058 1547
Hsd:WI kidney platinum level 0.9% sodium chloride solution (3 mg/kg/d) (for 6 days) then cisplatin (7 mg/kg) Kimoto Y, et al., J Vet Med Sci. 2013 Feb;75(2):159-64. Epub 2012 Oct 10. kidney molecular composition trait male 53.0 days 10 16.7 ug/g 1.96 6.2 inductively coupled plasma-atomic emission spectrometry 0.0 76063 1547
Hsd:WI body weight 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. body mass male  days 6 142.5 g 0.73 1.8 body weighing method 0.0 75953 1544
Hsd:WI serum creatinine level 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood creatinine amount male  days 6 1.11 mg/dl 0.25 0.62 serum creatinine analysis 0.0 75974 1544
Hsd:WI serum urea nitrogen level silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood urea nitrogen amount male  days 6 75.2 mg/dl 2.16 5.3 liquid phase colorimetry 0.0 75979 1544
Hsd:WI serum urea nitrogen level lycopene (6 mg/kg/d) (for 12 days) then cisplatin (7 mg/kg) Erman F, et al., Biol Trace Elem Res. 2014 Feb 16. blood urea nitrogen amount not specified 78.0 days 7 62.43 mg/dl 5.35 14.15 serum urea analysis 0.0 76049 1546
Hsd:WI kidney superoxide dismutase to catalase activity ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male  days 8 2.92 null 0.11 0.32 liquid phase colorimetry 0.0 76220 1542
Hsd:WI kidney superoxide dismutase to glutathione peroxidase ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male  days 8 18.63 null 0.61 1.73 liquid phase colorimetry 0.0 76224 1542
Hsd:WI both kidneys wet weight vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney mass male  days 6 1.2 g 0.05 0.13 post excision weight measurement 0.0 75957 1544
Hsd:WI kidney lipid peroxide level 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney lipid peroxide amount male  days 6 0.83 nmol/mg 0.04 0.09 liquid phase colorimetry 0.0 76258 1544
Hsd:WI plasma urea nitrogen level 0.9% sodium chloride solution (3 mg/kg/d) (for 6 days) then cisplatin (7 mg/kg) Kimoto Y, et al., J Vet Med Sci. 2013 Feb;75(2):159-64. Epub 2012 Oct 10. blood urea nitrogen amount male 55.0 days 6 44.38 mmol/l 4.07 9.96 plasma urea nitrogen analysis 0.0 76052 1547
Hsd:WI kidney superoxide dismutase activity to total protein level ratio vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney superoxide dismutase activity male  days 6 8.13 U/mg 0.79 1.94 liquid phase colorimetry 0.0 76188 1544
Hsd:WI kidney superoxide dismutase activity to total protein level ratio 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney superoxide dismutase activity male  days 6 10.11 U/mg 0.22 0.54 liquid phase colorimetry 0.0 76189 1544
Hsd:WI kidney glutathione level cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione amount male  days 8 108.4 ug/g 4.56 12.9 liquid phase colorimetry 0.0 76232 1542
Hsd:WI kidney catalase activity to total protein level ratio silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. catalase activity male  days 6 30.56 nmol/mg 0.37 0.9 liquid phase colorimetry 0.0 76237 1544
Hsd:WI kidney paraoxonase1 activity to total protein level ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney paraoxonase 1 activity male  days 8 14.83 U/mg 0.43 1.21 liquid phase colorimetry 0.0 76212 1542
Hsd:WI kidney glutathione peroxidase activity to glutathione reductase activity ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione peroxidase activity male  days 8 62.54 null 2.21 6.24 liquid phase colorimetry 0.0 76215 1542
Hsd:WI body weight silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. body mass male  days 6 143.6 g 0.41 1.0 body weighing method 0.0 75954 1544
Hsd:WI timed urine volume silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. urine output male  days 6 9.2 ml/d 0.69 1.7 urine volume measurement method 0.0 75968 1544
Hsd:WI kidney glutathione level cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione amount male  days 8 58.72 ug/g 3.78 10.7 liquid phase colorimetry 0.0 76231 1542
Hsd:WI plasma urea nitrogen level 0.9% sodium chloride solution (3 mg/kg/d) (for 6 days) then cisplatin (7 mg/kg) Kimoto Y, et al., J Vet Med Sci. 2013 Feb;75(2):159-64. Epub 2012 Oct 10. blood urea nitrogen amount male 53.0 days 6 8.68 mmol/l 0.66 1.63 plasma urea nitrogen analysis 0.0 76056 1547
Hsd:WI plasma urea nitrogen level cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood urea nitrogen amount male  days 8 20.62 mmol/l 1.27 3.61 liquid phase colorimetry 0.0 75941 1542
Hsd:WI kidney glutathione peroxidase activity to total protein level ratio 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione peroxidase activity male  days 6 13.39 U/mg 0.09 0.21 liquid phase colorimetry 0.0 76193 1544
Hsd:WI kidney glutathione peroxidase activity to total protein level ratio silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione peroxidase activity male  days 6 15.4 U/mg 0.29 0.71 liquid phase colorimetry 0.0 76194 1544
Hsd:WI kidney platinum level lactotransferrin (300 mg/kg/d) (for 6 days) then cisplatin (7 mg/kg) Kimoto Y, et al., J Vet Med Sci. 2013 Feb;75(2):159-64. Epub 2012 Oct 10. kidney molecular composition trait male 53.0 days 10 9.8 ug/g 2.1 6.64 inductively coupled plasma-atomic emission spectrometry 0.0 76064 1547
Hsd:WI both kidneys wet weight 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney mass male  days 6 0.86 g 0.03 0.07 post excision weight measurement 0.0 75958 1544
Hsd:WI both kidneys wet weight silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney mass male  days 6 0.84 g 0.03 0.08 post excision weight measurement 0.0 75959 1544
Hsd:WI plasma creatinine level cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood creatinine amount male  days 8 1.67 mg/dl 0.12 0.33 liquid phase colorimetry 0.0 75946 1542
Hsd:WI kidney superoxide dismutase activity to total protein level ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male  days 8 450.1 U/mg 3.15 8.91 liquid phase colorimetry 0.0 76201 1542
Hsd:WI kidney catalase activity to total protein level ratio vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. catalase activity male  days 6 21.73 nmol/mg 0.62 1.51 liquid phase colorimetry 0.0 76235 1544
Hsd:WI kidney glutathione level 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione amount male  days 6 10012.49 ug/g 293.58 719.13 liquid phase colorimetry 0.0 76240 1544
Hsd:WI serum creatinine level silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood creatinine amount male  days 6 0.85 mg/dl 0.03 0.08 serum creatinine analysis 0.0 75975 1544
Hsd:WI serum urea nitrogen level 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood urea nitrogen amount male  days 6 89.7 mg/dl 2.9 7.11 liquid phase colorimetry 0.0 75978 1544
Hsd:WI serum creatinine level cisplatin (7 mg/kg) Erman F, et al., Biol Trace Elem Res. 2014 Feb 16. blood creatinine amount not specified 78.0 days 7 1.37 mg/dl 0.21 0.56 serum creatinine analysis 0.0 76040 1546
Hsd:WI serum creatinine level lycopene (6 mg/kg/d) (for 12 days) then cisplatin (7 mg/kg) Erman F, et al., Biol Trace Elem Res. 2014 Feb 16. blood creatinine amount not specified 78.0 days 7 0.4 mg/dl 0.01 0.03 serum creatinine analysis 0.0 76043 1546
Hsd:WI kidney glutathione level silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione amount male  days 6 9864.97 ug/g 200.74 491.71 liquid phase colorimetry 0.0 76241 1544
Hsd:WI kidney lipid peroxide level silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney lipid peroxide amount male  days 6 0.88 nmol/mg 0.02 0.06 liquid phase colorimetry 0.0 76259 1544
Hsd:WI body weight vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. body mass male  days 6 137.6 g 0.45 1.1 body weighing method 0.0 75952 1544
Hsd:WI timed urine volume 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. urine output male  days 6 10.0 ml/d 0.78 1.9 urine volume measurement method 0.0 75967 1544
Hsd:WI serum urea nitrogen level vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood urea nitrogen amount male  days 6 96.11 mg/dl 1.91 4.69 liquid phase colorimetry 0.0 75977 1544
Hsd:WI kidney glutathione peroxidase activity to total protein level ratio vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione peroxidase activity male  days 6 7.54 U/mg 0.51 1.24 liquid phase colorimetry 0.0 76192 1544
Hsd:WI plasma urea nitrogen level cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood urea nitrogen amount male  days 8 14.48 mmol/l 0.88 2.49 liquid phase colorimetry 0.0 75942 1542
Hsd:WI kidney glutathione level vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione amount male  days 6 7882.76 ug/g 178.16 436.39 liquid phase colorimetry 0.0 76239 1544
Hsd:WI plasma creatinine level 0.9% sodium chloride solution (3 mg/kg/d) (for 6 days) then cisplatin (7 mg/kg) Kimoto Y, et al., J Vet Med Sci. 2013 Feb;75(2):159-64. Epub 2012 Oct 10. blood creatinine amount male 53.0 days 6 0.31 mg/dl 0.03 0.07 plasma creatinine analysis 0.0 76060 1547
Hsd:WI kidney lipid peroxide level vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney lipid peroxide amount male  days 6 1.51 nmol/mg 0.03 0.08 liquid phase colorimetry 0.0 76257 1544
Hsd:WI kidney paraoxonase1 activity to total protein level ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney paraoxonase 1 activity male  days 8 9.57 U/mg 0.3 0.86 liquid phase colorimetry 0.0 76211 1542
Hsd:WI plasma creatinine level 0.9% sodium chloride solution (3 mg/kg/d) (for 6 days) then cisplatin (7 mg/kg) Kimoto Y, et al., J Vet Med Sci. 2013 Feb;75(2):159-64. Epub 2012 Oct 10. blood creatinine amount male 55.0 days 6 2.56 mg/dl 0.17 0.42 plasma creatinine analysis 0.0 76054 1547
Hsd:WI plasma creatinine level cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood creatinine amount male  days 8 2.85 mg/dl 0.25 0.71 liquid phase colorimetry 0.0 75945 1542
Hsd:WI kidney superoxide dismutase activity to total protein level ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male  days 8 292.4 U/mg 14.25 40.3 liquid phase colorimetry 0.0 76202 1542
Hsd:WI kidney catalase activity to total protein level ratio 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. catalase activity male  days 6 23.2 nmol/mg 0.29 0.7 liquid phase colorimetry 0.0 76236 1544
Hsd:WI kidney glutathione peroxidase activity to glutathione reductase activity ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione peroxidase activity male  days 8 46.14 null 1.7 4.82 liquid phase colorimetry 0.0 76216 1542
Hsd:WI plasma creatinine level lactotransferrin (300 mg/kg/d) (for 6 days) then cisplatin (7 mg/kg) Kimoto Y, et al., J Vet Med Sci. 2013 Feb;75(2):159-64. Epub 2012 Oct 10. blood creatinine amount male 53.0 days 6 0.15 mg/dl 0.02 0.05 plasma creatinine analysis 0.0 76062 1547
Hsd:WI kidney superoxide dismutase activity to total protein level ratio silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney superoxide dismutase activity male  days 6 11.74 U/mg 0.56 1.38 liquid phase colorimetry 0.0 76190 1544
Hsd:WI timed urine volume vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. urine output male  days 6 21.8 ml/d 1.31 3.2 urine volume measurement method 0.0 75966 1544
Hsd:WI serum creatinine level vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood creatinine amount male  days 6 1.69 mg/dl 0.06 0.14 serum creatinine analysis 0.0 75973 1544
Hsd:WI serum urea nitrogen level cisplatin (7 mg/kg) Erman F, et al., Biol Trace Elem Res. 2014 Feb 16. blood urea nitrogen amount not specified 78.0 days 7 124.33 mg/dl 12.59 33.31 serum urea analysis 0.0 76048 1546
Hsd:WI kidney superoxide dismutase to catalase activity ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male  days 8 6.67 null 0.3 0.85 liquid phase colorimetry 0.0 76219 1542
Hsd:WI kidney superoxide dismutase to glutathione peroxidase ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male  days 8 35.78 null 1.46 4.14 liquid phase colorimetry 0.0 76223 1542
Hsd:WI kidney superoxide dismutase to paraoxonase1 activity ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male  days 8 47.04 null 2.0 5.65 liquid phase colorimetry 0.0 76227 1542
Hsd:WI kidney superoxide dismutase to paraoxonase1 activity ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male  days 8 19.72 null 0.82 2.31 liquid phase colorimetry 0.0 76228 1542