Phenominer Database Results (243 hits)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
RHA/N number of periods of voluntary immobility auditory stimulus (63 dB) (for 0 hours) and visible light stimulus (7 W) (for 0 hours) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 locomotor behavior trait both 97 days-104 days 19 86.6 null 7.69 33.5 active avoidance test using a two-way shuttle box apparatus 0.0 0 68369 114
Hsd:SD scotopic A wave amplitude of ERG waveform vehicle control condition (2 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 4 142.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic a-wave ERG 108642 3128
RCS-p+/LavRrrc photopic B wave amplitude of ERG waveform GSK-812 (2 ul) then visible light stimulus (25 cd x s/m2) Baranov P, et al., J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422. doi: 10.1089/jop.2016.0121. Epub 2017 Apr 25. cone electrophysiology trait not specified 119 days 7 28.9 uV 2.5 6.61 electroretinography cornea 0.0 intravitrial injection 98 days 109740 3154
Hsd:SD scotopic A wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (40 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 173.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic a-wave ERG 108654 3128
RCS/LavRrrc b-wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. eye electrophysiology trait both 0 days 5 24.0 uV 10.0 22.36 electroretinography cornea 0.0 0 scotopic b-wave ERG 108665 3128
RCS/N scotopic A wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. rod electrophysiology trait not specified 62 days 6 16.0 uV 6.94 17.0 electroretinography cornea 0.0 AAV8 injection 60 days contralateral control eye scotopic a-wave amplitude ERG 108681 3129
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 352.0 uV 26.0 58.14 electroretinography cornea 0.0 plasmid delivery 37 days scotopic b-wave ERG 108701 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 24.7 uV 13.8 30.86 electroretinography cornea 0.0 59 days control for age matched plasmid injection scotopic b-wave ERG 108704 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) and gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 231.0 uV 5.0 8.66 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2 scotopic b-wave ERG 108749 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 199.0 uV 17.0 29.44 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic b-wave ERG 108750 3131
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 358.5 uV 35.71 87.47 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108459 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 12.43 uV 2.29 7.6 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108470 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 87.05 uV 8.87 29.42 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108472 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 334.55 uV 43.36 143.81 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108478 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 351.91 uV 47.74 158.34 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108479 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 56.72 uV 16.42 54.46 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108482 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 15.46 uV 4.1 10.04 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108488 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 178.0 uV 12.3 30.13 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108498 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 101.1 uV 20.75 50.83 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108506 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 208.5 uV 14.36 35.17 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108516 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 89.88 uV 11.06 27.09 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108521 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 143.17 uV 20.27 49.65 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108397 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 327.83 uV 16.41 40.2 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108405 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 371.67 uV 28.82 70.59 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108406 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 652.5 uV 65.65 160.81 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108415 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 11.22 uV 1.07 2.62 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108416 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 149.83 uV 9.83 24.08 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108425 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 202.33 uV 17.65 43.23 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108426 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 243.17 uV 24.11 59.06 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108427 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 65.42 uV 13.87 33.97 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108428 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 594.5 uV 24.04 58.89 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108433 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 399.83 uV 37.74 92.44 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108436 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 155.28 uV 13.68 33.51 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108443 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 201.67 uV 18.19 44.56 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108444 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 78.77 uV 13.41 32.85 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108448 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 218.83 uV 22.09 54.11 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108451 3123
Hsd:SD scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 488.0 uV electroretinography cornea 0.0 0 scotopic b-wave ERG 108647 3128
RCS/LavRrrc scotopic B wave amplitude of ERG waveform human periodontal ligament-derived stem cells (0.2 x 10E6 cells) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 49 days 4 204.9 uV 52.13 104.26 electroretinography retina 0.0 hPDLSC transplant 28 days 109857 3157
RCS/LavRrrc scotopic B wave amplitude of ERG waveform vehicle control condition (2 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 49 days 4 29.44 uV 7.44 14.87 electroretinography retina 0.0 pbs vehicle injection 28 days 109859 3157
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 135.0 uV 38.0 84.97 electroretinography cornea 0.0 plasmid delivery 59 days pVAX2-rGDNF scotopic b-wave ERG 108731 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 114.0 uV 16.0 35.78 electroretinography cornea 0.0 plasmid delivery 59 days scotopic b-wave ERG 108732 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 233.29 uV 18.61 49.24 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108546 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 251.29 uV 19.14 50.64 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108547 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 31.96 uV 9.73 25.74 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108553 3123
RCS/LavRrrc scotopic B wave amplitude of ERG waveform human periodontal ligament-derived stem cells (0.2 x 10E6 cells) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 77 days 4 45.89 uV 3.23 6.45 electroretinography retina 0.0 hPDLSC transplant 56 days 109860 3157
RLA/N number of entries into a discrete space in an experimental apparatus auditory stimulus (63 dB) (for 0 hours) and visible light stimulus (7 W) (for 0 hours) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 locomotor behavior trait both 97 days-104 days 18 3.17 null 0.71 3.0 active avoidance test using a two-way shuttle box apparatus 0.0 0 prompted 68361 114
RLA/N number of periods of voluntary immobility auditory stimulus (63 dB) (for 0 hours) and visible light stimulus (7 W) (for 0 hours) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 locomotor behavior trait both 97 days-104 days 18 263.2 null 7.8 33.1 active avoidance test using a two-way shuttle box apparatus 0.0 0 68370 114
RCS-p+/LavRrrc optokinetic reflex vehicle control condition (2 ul) then visible light stimulus (25 cd x s/m2) Baranov P, et al., J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422. doi: 10.1089/jop.2016.0121. Epub 2017 Apr 25. eye physiology trait not specified 119 days 7 6.0 s 0.27 0.71 optokinetic reflex test method 60.0 intravitrial injection 98 days 109741 3154
Hsd:SD scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 4 456.0 uV electroretinography cornea 0.0 0 scotopic b-wave ERG 108641 3128
RCS/N scotopic B wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. rod electrophysiology trait not specified 62 days 6 61.0 uV 19.6 48.0 electroretinography cornea 0.0 AAV8 injection 60 days contralateral control eye scotopic b-wave amplitude ERG 108683 3129
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 60.2 uV 8.5 19.01 electroretinography cornea 0.0 plasmid delivery 37 days scotopic a-wave ERG 108726 3131
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 144.39 uV 13.24 43.91 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108473 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 201.55 uV 19.9 66.0 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108475 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 270.09 uV 34.35 113.93 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108477 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 410.45 uV 48.4 160.52 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108483 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 607.73 uV 58.9 195.35 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108487 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 385.17 uV 61.99 151.84 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108501 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 587.17 uV 49.54 121.35 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108509 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 739.67 uV 44.42 108.81 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108527 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 748.17 uV 64.77 158.65 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108528 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 423.33 uV 25.5 62.46 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108534 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 108.63 uV 17.19 42.11 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108395 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 460.67 uV 47.48 116.3 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108411 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 27.7 uV 4.72 11.56 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108423 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 519.33 uV 29.94 73.34 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108432 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 42.97 uV 8.99 22.02 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108434 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 356.17 uV 23.35 57.2 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108435 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 6.38 uV 1.4 3.43 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108440 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 381.17 uV 37.99 93.06 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108453 3123
Hsd:SD photopic B wave amplitude of ERG waveform controlled visible light condition (30 cd x s/m2) then visible light stimulus (12 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. cone electrophysiology trait both 0 days 9 75.0 uV electroretinography cornea 0.0 subretinal injection 30 days contralateral control eye photopic b-wave ERG 108651 3128
RCS/N scotopic B wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.01 cd x s/m2) Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. rod electrophysiology trait not specified 242 days 4 223.0 uV 28.0 56.0 electroretinography cornea 0.0 AAV8 injection 240 days treated eye scotopic b-wave amplitude ERG 108684 3129
Hsd:SD scotopic A wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 4 202.0 uV electroretinography cornea 0.0 0 scotopic a-wave ERG 108643 3128
Hsd:SD scotopic B wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (4 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 387.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic b-wave ERG 108646 3128
RCS/N scotopic B wave amplitude of ERG waveform lensotomy then controlled exposure to darkness (for 1 days) then visible light stimulus (100 cd x s/m2) Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. rod electrophysiology trait not specified 60 days 3 30.5 uV 7.51 13.0 electroretinography cornea 0.0 lens puncture 30 days scotopic b-wave ERG 108567 3124
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 172.6 uV 20.12 49.28 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108515 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 5.86 uV 0.76 2.01 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108536 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 36.49 uV 10.37 27.44 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108541 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 83.4 uV 14.8 39.16 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108543 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 24.79 uV 7.82 20.69 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108552 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 94.13 uV 15.33 40.56 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108556 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 159.83 uV 21.35 56.49 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108558 3123
RCS/LavRrrc scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 35 days 4 61.63 uV 15.09 30.17 electroretinography retina 0.0 untreated control 14 days 109855 3157
RCS/LavRrrc scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 77 days 4 12.57 uV 1.42 2.84 electroretinography retina 0.0 untreated control 56 days 109861 3157
N:HS number of entries into a discrete space in an experimental apparatus auditory stimulus (63 dB) (for 0 hours) and visible light stimulus (7 W) (for 0 hours) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 locomotor behavior trait both 97 days-104 days 20 2.6 null 0.93 4.14 active avoidance test using a two-way shuttle box apparatus 0.0 0 prompted 68359 114
RHA/N number of entries into a discrete space in an experimental apparatus auditory stimulus (63 dB) (for 0 hours) and visible light stimulus (7 W) (for 0 hours) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 locomotor behavior trait both 97 days-104 days 19 25.88 null 1.26 5.5 active avoidance test using a two-way shuttle box apparatus 0.0 0 prompted 68360 114
RCS/N ERG oscillatory potential lensotomy then controlled visible light exposure (for 0.2 hours) then visible light stimulus (100 cd x s/m2) Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. eye electrophysiology trait not specified 60 days 3 33.1 uV 2.19 3.8 electroretinography cornea 0.0 lens puncture 30 days photopic ocillatory index 108570 3124
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87 days 5 83.0 uV 7.0 15.65 electroretinography cornea 0.0 plasmid delivery 71 days pVAX2-rGDNF scotopic b-wave ERG 108735 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87 days 5 110.0 uV 14.0 31.3 electroretinography cornea 0.0 plasmid delivery 71 days scotopic b-wave ERG 108736 3131
RCS-p+/LavRrrc photopic B wave amplitude of ERG waveform vehicle control condition (2 ul) then visible light stimulus (25 cd x s/m2) Baranov P, et al., J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422. doi: 10.1089/jop.2016.0121. Epub 2017 Apr 25. cone electrophysiology trait not specified 119 days 7 23.1 uV 1.0 2.65 electroretinography cornea 0.0 intravitrial injection 98 days 109739 3154
Hsd:SD scotopic B wave amplitude of ERG waveform vehicle control condition (2 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 4 338.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic b-wave ERG 108640 3128
Hsd:SD scotopic B wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (40 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 397.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic b-wave ERG 108652 3128
RCS/LavRrrc b-wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (40 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. eye electrophysiology trait both 0 days 5 137.0 uV 18.0 40.25 electroretinography cornea 0.0 subretinal injection 60 days scotopic b-wave ERG 108664 3128
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 186.0 uV 23.8 53.22 electroretinography cornea 0.0 37 days control for age matched plasmid injection scotopic b-wave ERG 108702 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) and gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 23.8 uV 1.9 3.29 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2 scotopic a-wave ERG 108746 3131
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 8.81 uV 1.84 4.51 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108392 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 78.43 uV 13.51 33.09 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108394 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 9.73 uV 2.39 5.85 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108398 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 161.92 uV 30.48 74.66 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108401 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 224.32 uV 34.64 84.85 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108403 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 62.22 uV 18.42 45.12 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108410 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 638.33 uV 68.2 167.06 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108414 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 23.02 uV 5.24 12.84 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108417 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 95.25 uV 7.15 17.51 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108418 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 162.07 uV 9.02 22.09 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108419 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 7.62 uV 1.56 3.82 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108422 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 382.17 uV 30.52 74.76 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108430 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 497.33 uV 42.65 104.47 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108437 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 570.67 uV 21.08 51.64 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108438 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 621.67 uV 35.23 86.3 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108439 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 25.21 uV 4.23 10.36 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108441 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 88.5 uV 12.52 30.67 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108442 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 26.68 uV 7.67 18.79 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108447 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 146.78 uV 16.49 40.39 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108449 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 440.0 uV 43.67 106.97 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108454 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 587.83 uV 53.2 130.31 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108456 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 579.0 uV 50.99 124.9 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108457 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 516.5 uV 29.8 72.99 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108461 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 584.5 uV 38.15 93.45 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108462 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 598.67 uV 39.64 97.1 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108463 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 389.91 uV 52.11 172.83 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108480 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 80.6 uV 11.3 27.68 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108490 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 605.83 uV 62.69 153.56 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108505 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 533.17 uV 67.99 166.54 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108508 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 570.67 uV 53.5 131.05 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108510 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 625.0 uV 55.4 135.7 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108511 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 19.36 uV 3.48 8.52 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108513 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 800.0 uV 67.71 165.85 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108529 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 47.53 uV 9.4 23.03 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108530 3123
Hsd:SD scotopic A wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (4 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 154.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic a-wave ERG 108648 3128
RCS/LavRrrc scotopic B wave amplitude of ERG waveform human periodontal ligament-derived stem cells (0.2 x 10E6 cells) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 35 days 4 143.41 uV 12.18 24.35 electroretinography retina 0.0 hPDLSC transplant 14 days 109854 3157
RCS/N scotopic A wave amplitude of ERG waveform lensotomy then controlled exposure to darkness (for 1 days) then visible light stimulus (100 cd x s/m2) Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. rod electrophysiology trait not specified 60 days 3 18.3 uV 4.79 8.3 electroretinography cornea 0.0 lens puncture 30 days scotopic a-wave ERG 108566 3124
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 352.0 uV 26.0 58.14 electroretinography cornea 0.0 plasmid delivery 37 days scotopic b-wave ERG 108728 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 23.1 uV 4.0 8.94 electroretinography cornea 0.0 plasmid delivery 59 days scotopic a-wave ERG 108730 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 18.53 uV 4.77 12.63 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108538 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 145.24 uV 12.56 33.23 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108544 3123
RLA/N time to first movement outside a discrete space in an experimental apparatus auditory stimulus (63 dB) (for 0 hours) and visible light stimulus (7 W) (for 0 hours) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 locomotor behavior trait both 97 days-104 days 18 15.93 s 1.27 5.4 active avoidance test using a two-way shuttle box apparatus 0.0 0 following stimulus 68364 114
RCS/N ERG oscillatory potential lensotomy then controlled exposure to darkness (for 1 days) then visible light stimulus (100 cd x s/m2) Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. eye electrophysiology trait not specified 60 days 3 67.6 uV 16.69 28.9 electroretinography cornea 0.0 lens puncture 30 days scotopic ocillatory index ERG 108568 3124
RCS/N photopic B wave amplitude of ERG waveform lensotomy then controlled visible light exposure (for 0.2 hours) then visible light stimulus (100 cd x s/m2) Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. cone electrophysiology trait not specified 60 days 3 13.7 uV 2.19 3.8 electroretinography cornea 0.0 lens puncture 30 days photopic b-wave ERG 108569 3124
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87 days 5 17.1 uV 3.2 7.16 electroretinography cornea 0.0 plasmid delivery 71 days pVAX2-rGDNF scotopic a-wave ERG 108733 3131
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 438.83 uV 24.27 59.45 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108460 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 5.17 uV 1.18 3.91 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108464 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 11.68 uV 2.42 8.03 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108465 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 104.17 uV 12.63 41.89 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108467 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 137.5 uV 12.91 42.82 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108469 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 44.02 uV 13.47 44.67 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108476 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 466.45 uV 51.69 171.44 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108484 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 518.55 uV 54.69 181.39 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108485 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 188.33 uV 15.56 38.11 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108493 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 13.98 uV 3.06 7.5 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108494 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 145.83 uV 14.32 35.08 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108497 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 206.0 uV 11.62 28.46 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108499 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 71.98 uV 18.54 45.41 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108500 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 429.5 uV 66.11 161.94 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108502 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 485.67 uV 73.15 179.18 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108503 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 511.83 uV 65.06 159.36 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108504 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 393.0 uV 65.49 160.42 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108507 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 16.12 uV 3.84 9.41 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108512 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 57.63 uV 8.8 21.56 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108520 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 124.83 uV 7.26 17.78 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108522 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 119.08 uV 22.02 53.94 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108524 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 584.5 uV 55.51 135.97 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108525 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 382.33 uV 22.98 56.29 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108532 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 11.45 uV 3.56 9.42 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108537 3123
Hsd:SD photopic B wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (4 x 10E8 vg) then controlled visible light condition (30 cd x s/m2) then visible light stimulus (12 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. cone electrophysiology trait both 0 days 9 59.0 uV electroretinography cornea 0.0 subretinal injection 30 days photopic b-wave ERG 108650 3128
Hsd:SD scotopic A wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 203.0 uV electroretinography cornea 0.0 0 scotopic a-wave ERG 108655 3128
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 114.0 uV 16.1 36.0 electroretinography cornea 0.0 plasmid delivery 59 days scotopic b-wave ERG 108703 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 29.7 uV 11.3 25.27 electroretinography cornea 0.0 plasmid delivery 59 days pVAX2-rGDNF scotopic a-wave ERG 108729 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 26.7 uV 2.7 4.68 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic a-wave ERG 108747 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 144.0 uV 29.0 50.23 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic b-wave ERG 108751 3131
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 25.3 uV 2.85 6.98 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108399 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 240.67 uV 14.84 36.35 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108421 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 373.83 uV 17.47 42.79 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108429 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 437.0 uV 33.32 81.62 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108431 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 216.67 uV 19.46 47.67 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108445 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 8.38 uV 1.81 4.43 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108446 3123
Hsd:SD photopic B wave amplitude of ERG waveform vehicle control condition (2 ul) then controlled visible light condition (30 cd x s/m2) then visible light stimulus (12 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. cone electrophysiology trait both 0 days 4 51.0 uV electroretinography cornea 0.0 subretinal injection 30 days photopic b-wave ERG 108644 3128
Hsd:SD scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 491.0 uV electroretinography cornea 0.0 0 scotopic b-wave ERG 108653 3128
RCS/N scotopic A wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. rod electrophysiology trait not specified 62 days 6 175.0 uV 14.7 36.0 electroretinography cornea 0.0 AAV8 injection 60 days treated eye scotopic a-wave amplitude ERG 108680 3129
RCS/LavRrrc scotopic B wave amplitude of ERG waveform vehicle control condition (2 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 77 days 4 13.01 uV 1.85 3.69 electroretinography retina 0.0 pbs vehicle injection 56 days 109862 3157
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 475.0 uV 41.0 91.68 electroretinography cornea 0.0 plasmid delivery 37 days pVAX2-rGDNF scotopic b-wave ERG 108727 3131
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 112.85 uV 11.14 27.29 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108514 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 455.17 uV 35.54 87.05 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108535 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 27.22 uV 4.74 12.54 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108539 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 33.73 uV 9.28 24.55 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108540 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 7.44 uV 1.43 3.78 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108542 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 192.0 uV 14.42 38.15 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108545 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 3.13 uV 1.81 4.79 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108548 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 19.05 uV 3.75 9.92 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108550 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 31.22 uV 8.16 21.59 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108551 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 10.28 uV 1.69 4.47 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108554 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 179.49 uV 20.75 54.9 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108559 3123
N:HS time to first movement outside a discrete space in an experimental apparatus auditory stimulus (63 dB) (for 0 hours) and visible light stimulus (7 W) (for 0 hours) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 locomotor behavior trait both 97 days-104 days 20 14.32 s 1.24 5.56 active avoidance test using a two-way shuttle box apparatus 0.0 0 following stimulus 68362 114
RHA/N time to first movement outside a discrete space in an experimental apparatus auditory stimulus (63 dB) (for 0 hours) and visible light stimulus (7 W) (for 0 hours) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 locomotor behavior trait both 97 days-104 days 19 5.97 s 0.3 1.3 active avoidance test using a two-way shuttle box apparatus 0.0 0 following stimulus 68363 114
N:HS number of periods of voluntary immobility auditory stimulus (63 dB) (for 0 hours) and visible light stimulus (7 W) (for 0 hours) Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 locomotor behavior trait both 97 days-104 days 20 257.49 null 10.29 46.03 active avoidance test using a two-way shuttle box apparatus 0.0 0 68368 114
RCS-p+/LavRrrc optokinetic reflex GSK-812 (2 ul) then visible light stimulus (25 cd x s/m2) Baranov P, et al., J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422. doi: 10.1089/jop.2016.0121. Epub 2017 Apr 25. eye physiology trait not specified 119 days 7 8.2 s 0.4 1.06 optokinetic reflex test method 60.0 intravitrial injection 98 days 109742 3154
Hsd:SD photopic B wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (40 x 10E8 vg) then controlled visible light condition (30 cd x s/m2) then visible light stimulus (12 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. cone electrophysiology trait both 0 days 9 57.0 uV electroretinography cornea 0.0 subretinal injection 30 days photopic b-wave ERG 108656 3128
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87 days 5 24.5 uV 4.9 10.96 electroretinography cornea 0.0 plasmid delivery 71 days scotopic a-wave ERG 108734 3131
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 49.97 uV 12.07 29.57 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108458 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 71.37 uV 8.23 27.3 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108466 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 118.51 uV 12.59 41.76 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108468 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 18.46 uV 3.3 10.94 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108471 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 170.91 uV 16.52 54.79 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108474 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 410.09 uV 45.37 150.48 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108481 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 567.73 uV 56.78 188.32 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108486 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 24.73 uV 6.11 14.97 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108489 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 119.33 uV 19.43 47.59 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108491 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 166.85 uV 19.57 47.94 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108492 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 30.66 uV 9.93 24.32 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108495 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 100.23 uV 12.78 31.3 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108496 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 241.17 uV 16.89 41.37 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108517 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 16.61 uV 4.28 10.48 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108518 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 16.11 uV 3.41 8.35 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108519 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 138.93 uV 9.28 22.73 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108523 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 644.33 uV 50.52 123.75 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108526 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 354.0 uV 16.81 41.18 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108531 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 419.0 uV 21.83 53.47 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108533 3123
Hsd:SD photopic B wave amplitude of ERG waveform controlled visible light condition (30 cd x s/m2) then visible light stimulus (12 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. cone electrophysiology trait both 0 days 4 90.0 uV electroretinography cornea 0.0 subretinal injection 30 days contralateral control eye photopic b-wave ERG 108645 3128
Hsd:SD photopic B wave amplitude of ERG waveform controlled visible light condition (30 cd x s/m2) then visible light stimulus (12 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. cone electrophysiology trait both 0 days 9 70.0 uV electroretinography cornea 0.0 subretinal injection 30 days contralateral control eye photopic b-wave ERG 108657 3128
RCS/N photopic B wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled visible light condition (30 cd/m2) (for 0.1 hours) then visible light stimulus (10 cd x s/m2) and controlled visible light condition (30 cd/m2) Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. cone electrophysiology trait not specified 242 days 4 30.0 uV 5.5 11.0 electroretinography cornea 0.0 AAV8 injection 240 days treated eye photopic b-wave amplitude ERG 108685 3129
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 96.3 uV 10.3 23.03 electroretinography cornea 0.0 plasmid delivery 37 days pVAX2-rGDNF scotopic a-wave ERG 108725 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 20.9 uV 3.7 6.41 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic a-wave ERG 108748 3131
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 15.03 uV 4.72 11.56 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108393 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 118.43 uV 17.52 42.92 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108396 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 109.52 uV 22.74 55.7 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108400 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 190.68 uV 32.08 78.58 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108402 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 51.68 uV 12.61 30.89 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108404 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 391.5 uV 33.43 81.89 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108407 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 411.83 uV 43.52 106.6 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108408 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 430.17 uV 45.59 111.67 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108409 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 532.5 uV 62.77 153.75 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108412 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 592.83 uV 68.9 168.77 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108413 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 202.5 uV 12.47 30.55 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108420 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 94.57 uV 13.87 33.97 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108424 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 190.83 uV 21.76 53.3 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108450 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 56.16 uV 17.2 42.13 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108452 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 514.67 uV 47.85 117.21 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108455 3123
Hsd:SD scotopic A wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 195.0 uV electroretinography cornea 0.0 0 scotopic a-wave ERG 108649 3128
RCS/LavRrrc scotopic B wave amplitude of ERG waveform vehicle control condition (2 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 35 days 4 95.22 uV 16.19 32.38 electroretinography retina 0.0 pbs vehicle injection 14 days 109856 3157
RCS/LavRrrc scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 49 days 4 13.93 uV 1.49 2.98 electroretinography retina 0.0 untreated control 28 days 109858 3157
RCS/N scotopic B wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. rod electrophysiology trait not specified 62 days 6 500.0 uV 61.24 150.0 electroretinography cornea 0.0 AAV8 injection 60 days treated eye scotopic b-wave amplitude ERG 108682 3129
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 15.31 uV 2.98 7.88 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108549 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 32.75 uV 13.42 35.51 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108555 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 131.7 uV 16.13 42.68 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108557 3123