Phenominer Database Results (96 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Clinical Measurement Notes Record ID Study ID
WKY blood glucose level unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. blood glucose amount male 0 days 17 312.0 mg/dl 24.0 98.95 machine read blood glucose test strip 0.0 unx 168 days 99972 2378
WKY renal plasma flow to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney plasma flow trait male 0 days 16 3.19 ml/min/100g 0.13 0.52 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 168 days 99994 2378
WKY blood glucose level streptozotocin (60 mg/kg) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. blood glucose amount male 156 days 10 520.92 mg/dl 28.8 91.07 radioimmunoassay 0.0 0 99102 2219
WKY body weight streptozotocin (60 mg/kg) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. body mass male 156 days 10 259.65 g 18.96 59.96 body weighing method 0.0 0 99108 2219
WKY timed urine volume streptozotocin (60 mg/kg) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. urine output male 156 days 10 140.19 ml/d 10.38 32.82 urine volume measurement method 0.0 0 99120 2219
WKY timed urine volume streptozotocin (60 mg/kg) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 PFU) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. urine output male 156 days 10 62.68 ml/d 15.67 49.55 urine volume measurement method 0.0 0 99122 2219
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.52 ml/min/100g 0.03 0.07 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99947 2378
WKY renal vascular resistance unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. arterial blood pressure trait male 0 days 8 8.8 mmHg/ml/min 0.5 1.41 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 28 days 99962 2378
WKY renal vascular resistance unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. arterial blood pressure trait male 0 days 6 8.8 mmHg/ml/min 0.5 1.22 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 28 days 99964 2378
WKY timed urine volume unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. urine output male 0 days 8 41.62 ml/d 9.07 25.66 metabolic cage urine volume measurement method 0.0 unx 28 days 99968 2378
WKY heart weight to body weight ratio unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. heart mass male 0 days 17 3.2 g/kg 0.1 0.41 post excision weight measurement 0.0 unx 150 days 107452 2378
WKY body weight unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. body mass male 0 days 16 261.0 g 7.0 28.0 body weighing method 0.0 unx 150 days 107448 2378
WKY kidney glomerular tuft surface area unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney glomerulus size trait male 0 days 17 13.2 x 10E3 um2 3.3 13.61 ex vivo light microscopy with histochemistry 0.0 unx 150 days 107511 2378
WKY heart weight to body weight ratio unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) and bosentan (100 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. heart mass male 0 days 16 3.1 g/kg 0.1 0.4 post excision weight measurement 0.0 unx 150 days 107454 2378
WKY kidney glomerular surface area unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney glomerulus size trait male 0 days 17 17.0 x 10E3 um2 4.1 16.9 ex vivo light microscopy with histochemistry 0.0 unx 150 days kidney glomerulus surface area (CMO:0003488) 107462 2378
WKY hematocrit unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. erythrocyte quantity male 0 days 16 45.8 % 0.5 2.0 hematocrit analysis 0.0 unx 168 days 99978 2378
WKY timed urine volume unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. urine output male 0 days 16 49.25 ml/d 5.18 20.74 metabolic cage urine volume measurement method 0.0 unx 168 days 100004 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.26 null 0.01 0.04 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99956 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 6 0.21 null 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99959 2378
WKY hematocrit unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. erythrocyte quantity male 0 days 16 44.5 % 0.6 2.4 hematocrit analysis 0.0 unx 168 days 99979 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 17 0.21 null 0.01 0.05 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99987 2378
WKY renal plasma flow to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney plasma flow trait male 0 days 17 3.3 ml/min/100g 0.11 0.45 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 168 days 99992 2378
WKY timed urine volume unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. urine output male 0 days 17 41.47 ml/d 4.46 18.41 metabolic cage urine volume measurement method 0.0 unx 168 days 100002 2378
WKY blood glucose level streptozotocin (60 mg/kg) then gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (40000000000 PFU) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. blood glucose amount male 156 days 10 533.7 mg/dl 25.56 80.83 radioimmunoassay 0.0 0 99103 2219
WKY blood glucose level streptozotocin (60 mg/kg) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 null) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. blood glucose amount male 156 days 10 523.26 mg/dl 27.18 85.95 radioimmunoassay 0.0 0 99104 2219
WKY body weight streptozotocin (60 mg/kg) then gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (40000000000 null) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. body mass male 156 days 10 261.43 g 21.34 67.48 body weighing method 0.0 0 99109 2219
WKY body weight streptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 null) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. body mass male 156 days 10 286.6 g 21.95 69.41 body weighing method 0.0 0 99112 2219
WKY single kidney wet weight to body weight ratio streptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 PFU) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. kidney mass male 156 days 10 4.72 g/kg 0.31 0.98 post excision weight measurement 0.0 0 99118 2219
WKY body weight unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. body mass male 0 days 8 215.0 g 10.0 28.28 body weighing method 0.0 unx 28 days 99936 2378
WKY renal plasma flow to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney plasma flow trait male 0 days 8 2.32 ml/min/100g 0.11 0.31 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 28 days 99953 2378
WKY body weight unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) and bosentan (100 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. body mass male 0 days 16 267.0 g 9.0 36.0 body weighing method 0.0 unx 150 days 107449 2378
WKY left kidney wet weight to body weight ratio unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney mass male 0 days 16 8.1 mg/g 0.2 0.8 post excision weight measurement 0.0 unx 150 days 107458 2378
WKY kidney glomerular surface area unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) and bosentan (100 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney glomerulus size trait male 0 days 16 16.4 x 10E3 um2 4.1 16.4 ex vivo light microscopy with histochemistry 0.0 unx 150 days kidney glomerulus surface area (CMO:0003488) 107464 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.79 ml/min/100g 0.03 0.08 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99946 2378
WKY renal vascular resistance unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. arterial blood pressure trait male 0 days 8 9.2 mmHg/ml/min 0.4 1.13 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 28 days 99963 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 17 0.69 ml/min/100g 0.03 0.13 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99982 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 16 0.22 null 0.01 0.04 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99988 2378
WKY renal plasma flow to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney plasma flow trait male 0 days 16 3.15 ml/min/100g 0.13 0.52 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 168 days 99993 2378
WKY timed urine volume unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. urine output male 0 days 17 39.46 ml/d 4.61 19.0 metabolic cage urine volume measurement method 0.0 unx 168 days 100001 2378
WKY single kidney wet weight to body weight ratio streptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. kidney mass male 156 days 10 4.73 g/kg 0.37 1.17 post excision weight measurement 0.0 0 99117 2219
WKY timed urine volume streptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 PFU) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. urine output male 156 days 10 53.91 ml/d 7.67 24.25 urine volume measurement method 0.0 0 99124 2219
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 16 0.66 ml/min/100g 0.02 0.09 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99983 2378
WKY blood glucose level streptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 null) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. blood glucose amount male 156 days 10 534.6 mg/dl 22.5 71.15 radioimmunoassay 0.0 0 99106 2219
WKY body weight streptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. body mass male 156 days 10 287.24 g 20.18 63.81 body weighing method 0.0 0 99111 2219
WKY blood glucose level unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. blood glucose amount male 0 days 6 367.0 mg/dl 12.0 29.39 machine read blood glucose test strip 0.0 unx 28 days 99944 2378
WKY body weight unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. body mass male 0 days 17 256.0 g 5.0 20.62 body weighing method 0.0 unx 150 days 107446 2378
WKY heart weight to body weight ratio unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. heart mass male 0 days 17 3.5 g/kg 0.1 0.41 post excision weight measurement 0.0 unx 150 days 107451 2378
WKY kidney glomerular surface area unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney glomerulus size trait male 0 days 17 19.3 x 10E3 um2 4.8 19.79 ex vivo light microscopy with histochemistry 0.0 unx 150 days kidney glomerulus surface area (CMO:0003488) 107461 2378
WKY kidney glomerular tuft surface area unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) and bosentan (100 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney glomerulus size trait male 0 days 16 11.7 x 10E3 um2 2.9 11.6 ex vivo light microscopy with histochemistry 0.0 unx 150 days 107514 2378
WKY blood glucose level unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. blood glucose amount male 0 days 17 324.0 mg/dl 13.0 53.6 machine read blood glucose test strip 0.0 unx 168 days 99971 2378
WKY blood glucose level unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. blood glucose amount male 0 days 16 308.0 mg/dl 15.0 60.0 machine read blood glucose test strip 0.0 unx 168 days 99973 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 17 0.29 null 0.01 0.05 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99986 2378
WKY renal plasma flow to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney plasma flow trait male 0 days 8 2.33 ml/min/100g 0.09 0.25 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 28 days 99952 2378
WKY timed urine volume unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. urine output male 0 days 8 38.02 ml/d 5.33 15.07 metabolic cage urine volume measurement method 0.0 unx 28 days 99967 2378
WKY blood glucose level unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. blood glucose amount male 0 days 16 317.0 mg/dl 19.0 76.0 machine read blood glucose test strip 0.0 unx 168 days 99974 2378
WKY hematocrit unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. erythrocyte quantity male 0 days 17 44.8 % 0.6 2.47 hematocrit analysis 0.0 unx 168 days 99976 2378
WKY hematocrit unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. erythrocyte quantity male 0 days 17 45.6 % 0.3 1.24 hematocrit analysis 0.0 unx 168 days 99977 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 17 0.5 ml/min/100g 0.03 0.12 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99981 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 16 0.21 null 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99989 2378
WKY blood glucose level streptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. blood glucose amount male 156 days 10 537.12 mg/dl 28.98 91.64 radioimmunoassay 0.0 0 99105 2219
WKY body weight streptozotocin (60 mg/kg) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 null) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. body mass male 156 days 10 295.56 g 21.89 69.22 body weighing method 0.0 0 99110 2219
WKY single kidney wet weight to body weight ratio streptozotocin (60 mg/kg) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. kidney mass male 156 days 10 5.47 g/kg 0.46 1.45 post excision weight measurement 0.0 0 99114 2219
WKY single kidney wet weight to body weight ratio streptozotocin (60 mg/kg) then gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (40000000000 PFU) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. kidney mass male 156 days 10 5.42 g/kg 0.51 1.61 post excision weight measurement 0.0 0 99115 2219
WKY body weight unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. body mass male 0 days 8 233.0 g 5.0 14.14 body weighing method 0.0 unx 28 days 99938 2378
WKY body weight unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. body mass male 0 days 6 229.0 g 6.0 14.7 body weighing method 0.0 unx 28 days 99939 2378
WKY blood glucose level unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. blood glucose amount male 0 days 8 350.0 mg/dl 18.0 50.91 machine read blood glucose test strip 0.0 unx 28 days 99941 2378
WKY blood glucose level unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. blood glucose amount male 0 days 8 357.0 mg/dl 11.0 31.11 machine read blood glucose test strip 0.0 unx 28 days 99943 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.23 null 0.12 0.34 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99957 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.23 null 0.14 0.4 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99958 2378
WKY timed urine volume unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. urine output male 0 days 8 23.47 ml/d 1.73 4.89 metabolic cage urine volume measurement method 0.0 unx 28 days 99966 2378
WKY kidney glomerular tuft surface area unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney glomerulus size trait male 0 days 16 11.1 x 10E3 um2 2.8 11.2 ex vivo light microscopy with histochemistry 0.0 unx 150 days kidney glomerulus surface area (CMO:0003488) 107513 2378
WKY body weight unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. body mass male 0 days 17 274.0 g 6.0 24.74 body weighing method 0.0 unx 150 days 107447 2378
WKY left kidney wet weight to body weight ratio unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney mass male 0 days 17 8.2 mg/g 0.2 0.82 post excision weight measurement 0.0 unx 150 days 107457 2378
WKY left kidney wet weight to body weight ratio unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) and bosentan (100 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney mass male 0 days 16 8.3 mg/g 0.2 0.8 post excision weight measurement 0.0 unx 150 days 107459 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 16 0.67 ml/min/100g 0.02 0.08 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99984 2378
WKY renal vascular resistance unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. arterial blood pressure trait male 0 days 17 6.6 mmHg/ml/min 0.3 1.24 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 168 days 99997 2378
WKY renal vascular resistance unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. arterial blood pressure trait male 0 days 16 6.8 mmHg/ml/min 0.3 1.2 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 168 days 99999 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.54 ml/min/100g 0.02 0.05 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99948 2378
WKY renal vascular resistance unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. arterial blood pressure trait male 0 days 8 9.0 mmHg/ml/min 0.4 1.13 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 28 days 99961 2378
WKY timed urine volume unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. urine output male 0 days 6 44.93 ml/d 8.78 21.52 metabolic cage urine volume measurement method 0.0 unx 28 days 99969 2378
WKY renal vascular resistance unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. arterial blood pressure trait male 0 days 17 16.7 mmHg/ml/min 1.4 5.77 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 168 days 99996 2378
WKY renal vascular resistance unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. arterial blood pressure trait male 0 days 16 7.1 mmHg/ml/min 0.3 1.2 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 168 days 99998 2378
WKY timed urine volume unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. urine output male 0 days 16 45.5 ml/d 5.04 20.16 metabolic cage urine volume measurement method 0.0 unx 168 days 100003 2378
WKY single kidney wet weight to body weight ratio streptozotocin (60 mg/kg) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 PFU) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. kidney mass male 156 days 10 4.46 g/kg 0.42 1.33 post excision weight measurement 0.0 0 99116 2219
WKY timed urine volume streptozotocin (60 mg/kg) then gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (40000000000 PFU) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. urine output male 156 days 10 133.86 ml/d 16.58 52.43 urine volume measurement method 0.0 0 99121 2219
WKY timed urine volume streptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. urine output male 156 days 10 58.33 ml/d 8.45 26.72 urine volume measurement method 0.0 0 99123 2219
WKY body weight unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. body mass male 0 days 8 236.0 g 7.0 19.8 body weighing method 0.0 unx 28 days 99937 2378
WKY blood glucose level unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. blood glucose amount male 0 days 8 352.0 mg/dl 17.0 48.08 machine read blood glucose test strip 0.0 unx 28 days 99942 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 6 0.5 ml/min/100g 0.02 0.06 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99949 2378
WKY renal plasma flow to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney plasma flow trait male 0 days 8 3.09 ml/min/100g 0.18 0.51 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 28 days 99951 2378
WKY heart weight to body weight ratio unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. heart mass male 0 days 16 3.1 g/kg 0.1 0.4 post excision weight measurement 0.0 unx 150 days 107453 2378
WKY left kidney wet weight to body weight ratio unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney mass male 0 days 17 9.9 mg/g 0.7 2.89 post excision weight measurement 0.0 unx 150 days 107456 2378
WKY kidney glomerular tuft surface area unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney glomerulus size trait male 0 days 17 11.8 x 10E3 um2 2.9 11.96 ex vivo light microscopy with histochemistry 0.0 unx 150 days kidney glomerulus surface area (CMO:0003488) 107512 2378
WKY kidney glomerular surface area unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney glomerulus size trait male 0 days 16 15.8 x 10E3 um2 4.0 16.0 ex vivo light microscopy with histochemistry 0.0 unx 150 days kidney glomerulus surface area (CMO:0003488) 107463 2378
WKY renal plasma flow to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney plasma flow trait male 0 days 17 1.72 ml/min/100g 0.11 0.45 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 168 days 99991 2378
WKY renal plasma flow to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. kidney plasma flow trait male 0 days 6 2.42 ml/min/100g 0.09 0.22 p-aminohippurate analysis by liquid phase colorimetry 0.0 unx 28 days 99954 2378