LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
heart left ventricle mass |
male |
112 days
| 9 |
23.8 |
mg/g |
0.8 |
2.4 |
post excision weight measurement |
0.0 |
|
0 |
|
102683 |
2703 |
LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
aorta mass |
male |
112 days
| 9 |
12.3 |
mg/100g |
0.4 |
1.2 |
post excision weight measurement |
0.0 |
|
0 |
|
102689 |
2703 |
SBH/Ygl |
heart weight |
controlled sodium chloride content diet (0.65 %) (for 98 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) |
Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. |
heart mass |
male |
98 days
| 7 |
1.07 |
g |
0.07 |
0.18 |
post excision weight measurement |
0.0 |
|
0 |
|
106710 |
3038 |
WKY |
heart weight to body weight ratio |
unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 136 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
heart mass |
male |
0 days
| 17 |
3.2 |
g/kg |
0.1 |
0.41 |
post excision weight measurement |
0.0 |
unx |
150 |
days |
107452 |
2378 |
WKY |
heart weight to body weight ratio |
unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) and bosentan (100 mg/kg/d) (for 136 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
heart mass |
male |
0 days
| 16 |
3.1 |
g/kg |
0.1 |
0.4 |
post excision weight measurement |
0.0 |
unx |
150 |
days |
107454 |
2378 |
LL/Mav |
aorta weight to body weight ratio |
streptozotocin (100 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
aorta mass |
male |
112 days
| 18 |
12.2 |
mg/100g |
0.3 |
1.27 |
post excision weight measurement |
0.0 |
|
0 |
|
102771 |
2721 |
WKY |
single kidney wet weight to body weight ratio |
streptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 PFU) |
Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. |
kidney mass |
male |
156 days
| 10 |
4.72 |
g/kg |
0.31 |
0.98 |
post excision weight measurement |
0.0 |
|
0 |
|
99118 |
2219 |
LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
heart left ventricle mass |
male |
112 days
| 8 |
24.4 |
mg/g |
0.4 |
1.13 |
post excision weight measurement |
0.0 |
|
0 |
|
102682 |
2703 |
MNS |
single kidney wet weight |
streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 42 days) |
Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. |
kidney mass |
male |
126 days
| 6 |
3.08 |
g |
0.13 |
0.31 |
post excision weight measurement |
0.0 |
|
0 |
|
104111 |
2907 |
MHS |
single kidney wet weight |
streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 42 days) |
Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. |
kidney mass |
male |
126 days
| 6 |
2.53 |
g |
0.22 |
0.55 |
post excision weight measurement |
0.0 |
|
0 |
|
104113 |
2907 |
WKY |
left kidney wet weight to body weight ratio |
unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
kidney mass |
male |
0 days
| 16 |
8.1 |
mg/g |
0.2 |
0.8 |
post excision weight measurement |
0.0 |
unx |
150 |
days |
107458 |
2378 |
LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112 days
| 9 |
7.02 |
g/kg |
0.18 |
0.54 |
post excision weight measurement |
0.0 |
|
0 |
|
102695 |
2703 |
WKY |
single kidney wet weight to body weight ratio |
streptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) |
Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. |
kidney mass |
male |
156 days
| 10 |
4.73 |
g/kg |
0.37 |
1.17 |
post excision weight measurement |
0.0 |
|
0 |
|
99117 |
2219 |
LL/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (100 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
kidney mass |
male |
112 days
| 18 |
6.61 |
g/kg |
0.08 |
0.34 |
post excision weight measurement |
0.0 |
|
0 |
|
102763 |
2721 |
LL/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (100 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
heart left ventricle mass |
male |
112 days
| 18 |
1.93 |
mg/g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
0 |
|
102767 |
2721 |
LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
aorta mass |
male |
112 days
| 14 |
13.1 |
mg/100g |
0.1 |
0.37 |
post excision weight measurement |
0.0 |
|
0 |
|
102773 |
2721 |
LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
aorta mass |
male |
112 days
| 8 |
13.5 |
mg/100g |
0.5 |
1.41 |
post excision weight measurement |
0.0 |
|
0 |
|
102688 |
2703 |
LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112 days
| 7 |
8.05 |
g/kg |
0.24 |
0.63 |
post excision weight measurement |
0.0 |
|
0 |
|
102697 |
2703 |
SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
0 days
| 8 |
2.14 |
g |
0.04 |
0.12 |
post excision weight measurement |
0.0 |
stz |
224 |
days |
99918 |
2358 |
SBH/Ygl |
heart weight |
controlled sodium chloride content diet (8 %) (for 42 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) |
Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. |
heart mass |
male |
98 days
| 7 |
1.03 |
g |
0.08 |
0.2 |
post excision weight measurement |
0.0 |
|
0 |
|
106711 |
3038 |
WKY |
heart weight to body weight ratio |
unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then vehicle control condition |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
heart mass |
male |
0 days
| 17 |
3.5 |
g/kg |
0.1 |
0.41 |
post excision weight measurement |
0.0 |
unx |
150 |
days |
107451 |
2378 |
LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
aorta mass |
male |
112 days
| 11 |
10.1 |
mg/100g |
0.2 |
0.66 |
post excision weight measurement |
0.0 |
|
0 |
|
102690 |
2703 |
SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
0 days
| 8 |
1.94 |
g |
0.02 |
0.07 |
post excision weight measurement |
0.0 |
stz |
154 |
days |
99893 |
2358 |
LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112 days
| 8 |
6.95 |
g/kg |
0.23 |
0.65 |
post excision weight measurement |
0.0 |
|
0 |
|
102694 |
2703 |
LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112 days
| 11 |
6.44 |
g/kg |
0.14 |
0.46 |
post excision weight measurement |
0.0 |
|
0 |
|
102696 |
2703 |
WKY |
single kidney wet weight to body weight ratio |
streptozotocin (60 mg/kg) |
Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. |
kidney mass |
male |
156 days
| 10 |
5.47 |
g/kg |
0.46 |
1.45 |
post excision weight measurement |
0.0 |
|
0 |
|
99114 |
2219 |
WKY |
single kidney wet weight to body weight ratio |
streptozotocin (60 mg/kg) then gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (40000000000 PFU) |
Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. |
kidney mass |
male |
156 days
| 10 |
5.42 |
g/kg |
0.51 |
1.61 |
post excision weight measurement |
0.0 |
|
0 |
|
99115 |
2219 |
WKY |
left kidney wet weight to body weight ratio |
unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 136 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
kidney mass |
male |
0 days
| 17 |
8.2 |
mg/g |
0.2 |
0.82 |
post excision weight measurement |
0.0 |
unx |
150 |
days |
107457 |
2378 |
WKY |
left kidney wet weight to body weight ratio |
unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) and bosentan (100 mg/kg/d) (for 136 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
kidney mass |
male |
0 days
| 16 |
8.3 |
mg/g |
0.2 |
0.8 |
post excision weight measurement |
0.0 |
unx |
150 |
days |
107459 |
2378 |
LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
heart left ventricle mass |
male |
112 days
| 14 |
2.25 |
mg/g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
0 |
|
102769 |
2721 |
LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
heart left ventricle mass |
male |
112 days
| 7 |
24.2 |
mg/g |
0.3 |
0.79 |
post excision weight measurement |
0.0 |
|
0 |
|
102685 |
2703 |
LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
aorta mass |
male |
112 days
| 7 |
12.5 |
mg/100g |
0.5 |
1.32 |
post excision weight measurement |
0.0 |
|
0 |
|
102691 |
2703 |
WKY |
single kidney wet weight to body weight ratio |
streptozotocin (60 mg/kg) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 PFU) |
Liu CX, etal., Mol Med. 2011 Jan-Feb;17(1-2):59-69. doi: 10.2119/molmed.2010.00111. Epub 2010 Sep 14. |
kidney mass |
male |
156 days
| 10 |
4.46 |
g/kg |
0.42 |
1.33 |
post excision weight measurement |
0.0 |
|
0 |
|
99116 |
2219 |
SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
0 days
| 8 |
2.18 |
g |
0.05 |
0.14 |
post excision weight measurement |
0.0 |
stz |
224 |
days |
99917 |
2358 |
WKY |
heart weight to body weight ratio |
unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
heart mass |
male |
0 days
| 16 |
3.1 |
g/kg |
0.1 |
0.4 |
post excision weight measurement |
0.0 |
unx |
150 |
days |
107453 |
2378 |
WKY |
left kidney wet weight to body weight ratio |
unilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then vehicle control condition |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
kidney mass |
male |
0 days
| 17 |
9.9 |
mg/g |
0.7 |
2.89 |
post excision weight measurement |
0.0 |
unx |
150 |
days |
107456 |
2378 |
LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
kidney mass |
male |
112 days
| 14 |
6.65 |
g/kg |
0.08 |
0.3 |
post excision weight measurement |
0.0 |
|
0 |
|
102765 |
2721 |
LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
heart left ventricle mass |
male |
112 days
| 11 |
19.9 |
mg/g |
0.5 |
1.66 |
post excision weight measurement |
0.0 |
|
0 |
|
102684 |
2703 |
SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
0 days
| 8 |
1.9 |
g |
0.04 |
0.1 |
post excision weight measurement |
0.0 |
stz |
154 |
days |
99894 |
2358 |