F344/NHsd |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
N-nitrosodiethylamine (150 mg/kg) then 2-acetamidofluorene (0.02 %) (for 210 days) then partial hepatectomy |
De Miglio MR, et al., Cancer Res 1999 Sep 15;59(18):4651-7. |
liver integrity trait |
not specified |
0 days
| 12 |
84.18 |
% |
3.64 |
12.61 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine |
224 |
days |
|
68353 |
912 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
ovariectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
19.0 |
% |
|
4.2 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67454 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
69.0 |
% |
|
9.8 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67458 |
655 |
F344/NRrrc |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy |
Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. |
liver integrity trait |
female |
0 days
| 3 |
8.92 |
% |
2.85 |
4.94 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethtlamine injection |
56 |
days |
|
68619 |
950 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
59.0 |
% |
|
9.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
67438 |
655 |
BN |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy |
Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. |
liver integrity trait |
female |
0 days
| 3 |
1.61 |
% |
0.46 |
0.8 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethtlamine injection |
56 |
days |
|
68620 |
950 |
F344/Crli |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
N-nitrosodiethylamine (150 mg/kg) then 2-acetamidofluorene (0.02 %) (for 15 days) then partial hepatectomy |
De Miglio MR, et al., Cancer Res 2002 Aug 1;62(15):4459-63. |
liver integrity trait |
not specified |
0 days
| 20 |
80.11 |
% |
6.33 |
28.32 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection |
224 |
days |
150mg/Kg body weight |
67755 |
789 |
BN/Crli |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
N-nitrosodiethylamine (150 mg/kg) then 2-acetamidofluorene (0.02 %) (for 15 days) then partial hepatectomy |
De Miglio MR, et al., Cancer Res 2002 Aug 1;62(15):4459-63. |
liver integrity trait |
not specified |
0 days
| 20 |
13.69 |
% |
1.99 |
8.9 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection |
224 |
days |
150mg/Kg body weight |
67758 |
789 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
female |
0 days
| 0 |
10.0 |
% |
|
4.1 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
67450 |
655 |
BN/SsNHsd |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
N-nitrosodiethylamine (150 mg/kg) then 2-acetamidofluorene (0.02 %) (for 210 days) then partial hepatectomy |
De Miglio MR, et al., Cancer Res 1999 Sep 15;59(18):4651-7. |
liver integrity trait |
not specified |
0 days
| 7 |
19.83 |
% |
2.09 |
5.53 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine |
224 |
days |
|
68354 |
912 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
33.0 |
% |
|
8.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67442 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
19.0 |
% |
|
5.4 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67446 |
655 |