F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) and 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
male |
0 days
| 5 |
25.7 |
pg/ml |
2.33 |
5.2 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67444 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
33.0 |
% |
|
8.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67442 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
male |
0 days
| 5 |
0.95 |
ng/ml |
0.09 |
0.21 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67439 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
male |
0 days
| 5 |
8.4 |
pg/ml |
0.9 |
2.01 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67440 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
male |
0 days
| 5 |
0.85 |
ng/ml |
0.03 |
0.07 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67443 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
liver tumorous lesion number to liver volume ratio |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
16820.0 |
/cm3 |
|
5100.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
Add |
67445 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
liver tumorous lesion number to liver volume ratio |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
9420.0 |
/cm3 |
|
990.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
Add "liver tumorous lesion number to liver volume ratio" (new term) as child of "calculated liver tumorous lesion number" (new term). |
67441 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
0.18 |
cm3 x 10000 |
|
0.11 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67793 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
0.47 |
cm3 x 10000 |
|
0.13 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67792 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
6.42 |
% |
|
0.99 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
pcna index |
68106 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
3.55 |
% |
|
0.98 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
pcna index |
68107 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
liver integrity trait |
male |
0 days
| 0 |
19.0 |
% |
|
5.4 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
|
67446 |
655 |