Phenominer Database Results (78 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
SR/Jr diastolic blood pressure controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait female 56 days-63 days 8 serial mean 83.0 mmHg 1.0 2.83 intra-aortic abdominal radiotelemetry 604800.0 0 5 s every 5 min daily for a week 11702 119
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 28 days) then controlled sodium content diet (8 %) (for 30 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-93 days 42 continuous mean 109.0 mmHg 3.0 19.44 vascular indwelling catheter method femoral artery 259200.0 0 3 h per day increase 66139 229
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 28 days) then controlled sodium content diet (8 %) (for 30 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-93 days 35 continuous mean 173.0 mmHg 7.0 41.41 vascular indwelling catheter method femoral artery 259200.0 0 3 h per day decrease 66140 229
SHRSP/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 207.9 mmHg 5.5 9.53 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65650 613
WKY/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 105.2 mmHg 2.9 5.02 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65672 613
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 123.9 mmHg 3.6 6.24 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65684 613
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 144.2 mmHg 12.1 20.96 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65690 613
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 134.1 mmHg 4.2 7.27 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65696 613
WKY.SHRSP-(Fst-Pklr)/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 120.6 mmHg 8.5 14.72 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65712 613
SS.SR-(D13Mit9-D13Mit1)/Jr diastolic blood pressure controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait female 56 days-63 days 8 serial mean 82.0 mmHg 1.0 2.83 intra-aortic abdominal radiotelemetry 604800.0 0 5 s every 5 min daily for a week 11710 119
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-94 days 35 continuous mean 185.0 mmHg 5.0 29.58 vascular indwelling catheter method femoral artery 259200.0 0 3 h per day 12004 229
DA/Bkl plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 0 days 11 47.39 ng/ml 10.77 35.72 radioimmunoassay 0.0 0 68639 970
DA.F344-(D10Arb20-D10Arb22)/Arb plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 0 days 9 89.91 ng/ml 18.48 55.45 radioimmunoassay 0.0 0 68648 970
WKY/NCrl systolic blood pressure controlled exposure to ambient light (for 12 hours) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 112 days 7 125.9 mmHg 0.49 1.3 vascular indwelling catheter method left common carotid artery 0.0 0 daytime (7 AM - 7 PM) 70081 1281
WKY.SHR-(D1Mgh14-D1Rat77)/Iwai diastolic blood pressure controlled exposure to ambient light (for 12 hours) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 112 days 8 88.0 mmHg 0.99 2.8 vascular indwelling catheter method left common carotid artery 0.0 0 daytime (7 AM - 7 PM) 70091 1281
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 126.6 mmHg 4.8 8.31 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65706 613
WKY.SHRSP-(Fst-Pklr)/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 95.6 mmHg 7.1 12.3 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65720 613
F344/NHsd plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 49 days-59 days 9 95.9 ng/ml 16.73 50.19 radioimmunoassay 0.0 0 68640 970
DA.F344(Cia3c)/Arb plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 0 days 6 169.18 ng/ml 16.59 40.64 radioimmunoassay 0.0 0 68645 970
DA.F344(Cia3e)/Arb plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 0 days 4 136.24 ng/ml 45.53 91.06 radioimmunoassay 0.0 0 68647 970
DA.F344-(D20Arb2-D20Arb8)/Arb plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 0 days 10 59.25 ng/ml 13.8 43.65 radioimmunoassay 0.0 0 68650 970
SHRSP/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 171.2 mmHg 5.3 9.18 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65658 613
WKY/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 4 continuous mean 96.8 mmHg 6.4 12.8 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65666 613
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 97.8 mmHg 6.8 11.78 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65704 613
DA.F344-(D4Arb30-D4Arb4)/Arb plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 0 days 8 114.3 ng/ml 31.78 89.9 radioimmunoassay 0.0 0 68642 970
DA.F344-(D4Uia2-D4Wox21)/Arb plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 0 days 9 182.15 ng/ml 15.49 46.48 radioimmunoassay 0.0 0 68646 970
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 163.5 mmHg 12.2 21.13 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65694 613
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 112.1 mmHg 7.2 12.47 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65708 613
SHRSP/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 152.9 mmHg 5.2 9.01 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65654 613
SHRSP/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 139.0 mmHg 3.4 5.89 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65660 613
DA.F344-(D4Got44-D4Arb21)/Arb plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 0 days 7 126.36 ng/ml 19.73 52.19 radioimmunoassay 0.0 0 68643 970
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (0.4 %) (for 28 days) then controlled sodium content diet (8 %) (for 30 days) then controlled exposure to ambient light (for 12 hours) then controlled exposure to darkness (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-93 days 35 continuous mean 7.0 mmHg 7.0 41.41 vascular indwelling catheter method femoral artery 0.0 0 left femoral artery decrease 64931 229
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 155.8 mmHg 3.7 6.41 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65698 613
SR/Jr diastolic blood pressure controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait male 70 days-77 days 7 serial mean 95.0 mmHg 4.0 10.58 intra-aortic abdominal radiotelemetry 604800.0 0 5 s every 5 min daily for a week 11698 119
SR/Jr systolic blood pressure controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait male 70 days-77 days 7 serial mean 138.0 mmHg 4.0 10.58 intra-aortic abdominal radiotelemetry 604800.0 0 5 s every 5 min daily for a week 11696 119
SS/JrHsdMcwi diastolic blood pressure controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-94 days 35 continuous mean 167.0 mmHg 4.0 23.66 vascular indwelling catheter method femoral artery 259200.0 0 3 h per day 12002 229
BN/NHsdMcwi diastolic blood pressure controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-94 days 42 continuous mean 94.0 mmHg 2.0 12.96 vascular indwelling catheter method femoral artery 259200.0 0 3 h per day 12009 229
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-94 days 42 continuous mean 109.0 mmHg 2.0 12.96 vascular indwelling catheter method femoral artery 259200.0 0 3 h per day 12012 229
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 1.5 days) then controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 96 days 24 continuous mean 141.0 mmHg 5.0 24.49 vascular indwelling catheter method femoral artery 10800.0 0 left femoral artery 12038 229
WKY/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 92.0 mmHg 2.9 5.02 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65668 613
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 167.6 mmHg 5.5 9.53 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65688 613
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 140.7 mmHg 8.0 13.86 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65700 613
WKY/NCrl systolic blood pressure controlled sodium content diet (8 %) (for 14 days) then controlled exposure to ambient light (for 14 days) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 126 days 7 126.4 mmHg 1.06 2.8 vascular indwelling catheter method left common carotid artery 0.0 0 daytime (7 AM - 7 PM) 70085 1281
SS/Jr absolute change in systolic blood pressure controlled sodium content diet (2 %) (between 34 and 38 days) then controlled exposure to darkness then controlled exposure to ambient light Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 73 days-80 days 8 22.6 mmHg 1.05 2.97 intra-aortic abdominal radiotelemetry 10 0 diurnal difference 65497 611
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (0.4 %) (for 28 days) then controlled sodium content diet (8 %) (for 30 days) then controlled exposure to ambient light (for 12 hours) then controlled exposure to darkness (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-93 days 42 continuous mean 4.5 mmHg 2.0 12.96 vascular indwelling catheter method femoral artery 0.0 0 left femoral artery increase 64928 229
SHRSP/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 173.4 mmHg 3.9 6.75 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65652 613
WKY/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 131.7 mmHg 3.2 5.54 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65664 613
WKY/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 4 continuous mean 110.0 mmHg 7.0 14.0 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65670 613
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 131.2 mmHg 5.5 9.53 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65678 613
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 147.8 mmHg 4.3 7.45 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65682 613
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 117.4 mmHg 3.9 6.75 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65692 613
WKY.SHRSP-(Fst-Pklr)/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 146.1 mmHg 2.2 3.81 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65710 613
WKY.SHRSP-(Fst-Pklr)/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 83.1 mmHg 6.6 11.43 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65716 613
WKY.SHRSP-(Fst-Pklr)/Gcrc mean arterial blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 115.0 mmHg 1.5 2.6 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65718 613
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-94 days 42 continuous mean 127.0 mmHg 3.0 19.44 vascular indwelling catheter method femoral artery 259200.0 0 3 h per day 12006 229
WKY.SHR-(D1Mgh14-D1Rat77)/Iwai systolic blood pressure controlled exposure to ambient light (for 12 hours) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 112 days 8 125.5 mmHg 0.57 1.6 vascular indwelling catheter method left common carotid artery 0.0 0 daytime (7 AM - 7 PM) 70089 1281
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait male 70 days-77 days 8 serial mean 127.0 mmHg 1.0 2.83 intra-aortic abdominal radiotelemetry 604800.0 0 5 s every 5 min daily for a week 11704 119
WKY.SHRSP-(Fst-Pklr)/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 99.5 mmHg 1.2 2.08 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65714 613
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait female 56 days-63 days 8 serial mean 118.0 mmHg 2.0 5.66 intra-aortic abdominal radiotelemetry 604800.0 0 5 s every 5 min daily for a week 11708 119
WKY.SHR-(D1Mgh14-D1Rat77)/Iwai systolic blood pressure controlled sodium content diet (8 %) (for 14 days) then controlled exposure to ambient light (for 12 hours) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 126 days 8 128.6 mmHg 0.81 2.3 vascular indwelling catheter method left common carotid artery 0.0 0 daytime (7 AM - 7 PM) 70093 1281
SHRSP/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 121.7 mmHg 3.1 5.37 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65656 613
WKY/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 4 continuous mean 136.6 mmHg 8.2 16.4 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65662 613
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 154.9 mmHg 3.7 6.41 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65676 613
SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 202.1 mmHg 12.4 21.48 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65686 613
WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 112.0 mmHg 5.6 9.7 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65702 613
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 1.5 days) then controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 96 days 21 continuous mean 96.0 mmHg 3.0 13.75 vascular indwelling catheter method femoral artery 10800.0 0 left femoral artery 13275 229
SS.LEW-(D1Rat211-D1Rat18)/Mco absolute change in systolic blood pressure controlled sodium content diet (2 %) (between 34 and 38 days) then controlled exposure to darkness then controlled exposure to ambient light Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 73 days-80 days 8 14.4 mmHg 1.63 4.61 intra-aortic abdominal radiotelemetry 10 0 diurnal difference 65502 611
SS.SR-(D13Mit9-D13Mit1)/Jr diastolic blood pressure controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait male 70 days-77 days 8 serial mean 89.0 mmHg 1.0 2.83 intra-aortic abdominal radiotelemetry 604800.0 0 5 s every 5 min daily for a week 11706 119
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-94 days 35 continuous mean 206.0 mmHg 6.0 35.5 vascular indwelling catheter method femoral artery 259200.0 0 3 h per day 11984 229
DA.F344-Aia1/2 plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 0 days 8 112.73 ng/ml 20.68 58.49 radioimmunoassay 0.0 0 68641 970
DA.F344-(D4Got44-D4Rat128)/Arb plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 0 days 8 84.7 ng/ml 18.48 52.26 radioimmunoassay 0.0 0 68644 970
WKY/NCrl diastolic blood pressure controlled exposure to ambient light (for 12 hours) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 112 days 7 88.7 mmHg 0.83 2.2 vascular indwelling catheter method left common carotid artery 0.0 0 daytime (7 AM - 7 PM) 70083 1281
WKY/NCrl diastolic blood pressure controlled sodium content diet (8 %) (for 14 days) then controlled exposure to ambient light (for 14 days) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 126 days 7 89.3 mmHg 0.76 2.0 vascular indwelling catheter method left common carotid artery 0.0 0 daytime (7 AM - 7 PM) 70087 1281
WKY.SHR-(D1Mgh14-D1Rat77)/Iwai diastolic blood pressure controlled sodium content diet (8 %) (for 14 days) then controlled exposure to ambient light (for 12 hours) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 126 days 8 90.6 mmHg 1.27 3.6 vascular indwelling catheter method left common carotid artery 0.0 0 daytime (7 AM - 7 PM) 70095 1281
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc diastolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait female 126 days-147 days 3 continuous mean 108.5 mmHg 3.6 6.24 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65680 613
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) and controlled exposure to ambient light Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. arterial blood pressure trait male 126 days-147 days 3 continuous mean 180.7 mmHg 2.5 4.33 intra-aortic abdominal radiotelemetry 1814400 0 Days (7 AM to 7 PM) 65674 613
SR/Jr systolic blood pressure controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait female 56 days-63 days 8 serial mean 124.0 mmHg 2.0 5.66 intra-aortic abdominal radiotelemetry 604800.0 0 5 s every 5 min daily for a week 11700 119
DA.F344-(D10Arb21-D10Arb22)/Arb plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 0 days 11 111.08 ng/ml 18.79 62.32 radioimmunoassay 0.0 0 68649 970