BDIX/OrlCrl |
blood CD25 cell count |
0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD25-positive T cell quantity |
male |
63 days-77 days |
16 |
|
661.0 |
cells/ul |
56.75 |
227.0 |
fluorescence-activated cell sorting method |
0.0 |
0 |
days |
baseline |
baseline saline control group |
111086 |
3196 |
BDIX/OrlCrl |
blood CD25 cell count |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD25-positive T cell quantity |
male |
91 days-105 days |
16 |
|
1631.0 |
cells/ul |
149.75 |
599.0 |
fluorescence-activated cell sorting method |
0.0 |
28 |
days |
saline control |
saline control group |
111088 |
3196 |
BDIX/OrlCrl |
blood CD4 cell count |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD4-positive T cell quantity |
male |
77 days-91 days |
16 |
|
2.76 |
x 1000 cells/ul |
0.24 |
0.96 |
fluorescence-activated cell sorting method |
0.0 |
14 |
days |
sham |
saline control group |
111107 |
3196 |
BDIX/OrlCrl |
post-insult time of death due to metastatic liver tumors |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
life span trait |
male |
98 days-144 days |
16 |
median |
80.5 |
d |
3.13 |
12.5 |
necropsy |
0.0 |
0 |
|
|
saline control group |
111142 |
3196 |
BDIX/OrlCrl |
ratio of survivors to total study population during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
life span trait |
male |
77 days-213 days |
16 |
|
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
150 |
days |
two treatment regimen |
saline control group |
111150 |
3196 |
BDIX/OrlCrl |
blood CD25 cell count |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD25-positive T cell quantity |
male |
111 days-125 days |
16 |
|
1917.0 |
cells/ul |
105.25 |
421.0 |
fluorescence-activated cell sorting method |
0.0 |
48 |
days |
saline control |
saline control group |
111089 |
3196 |
BDIX/OrlCrl |
blood CD4 cell count |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD4-positive T cell quantity |
male |
91 days-105 days |
16 |
|
1.81 |
x 1000 cells/ul |
0.08 |
0.32 |
fluorescence-activated cell sorting method |
0.0 |
28 |
days |
saline control |
saline control group |
111108 |
3196 |
BDIX/OrlCrl |
blood CD4 cell count |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD4-positive T cell quantity |
male |
111 days-125 days |
16 |
|
1.57 |
x 1000 cells/ul |
0.06 |
0.24 |
fluorescence-activated cell sorting method |
0.0 |
48 |
days |
saline control |
saline control group |
111109 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-144 days |
16 |
|
100.0 |
% |
|
|
necropsy |
0.0 |
0 |
|
two treatment regimen |
saline control group |
111154 |
3196 |
BDIX/OrlCrl |
blood CD8 cell count |
0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD8-positive T cell quantity |
male |
63 days-77 days |
16 |
|
1.83 |
x 10E6 cells/ml |
0.23 |
0.93 |
fluorescence-activated cell sorting method |
0.0 |
0 |
days |
baseline |
baseline saline control group |
111096 |
3196 |
BDIX/OrlCrl |
blood CD8 cell count |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD8-positive T cell quantity |
male |
77 days-91 days |
16 |
|
2.25 |
x 10E6 cells/ml |
0.18 |
0.72 |
fluorescence-activated cell sorting method |
0.0 |
14 |
days |
sham |
saline control group |
111097 |
3196 |
BDIX/OrlCrl |
blood CD8 cell count |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD8-positive T cell quantity |
male |
111 days-125 days |
16 |
|
0.92 |
x 10E6 cells/ml |
0.03 |
0.1 |
fluorescence-activated cell sorting method |
0.0 |
48 |
days |
saline control |
saline control group |
111099 |
3196 |
BDIX/OrlCrl |
blood CD25 cell count |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD25-positive T cell quantity |
male |
77 days-91 days |
16 |
|
2294.0 |
cells/ul |
205.0 |
820.0 |
fluorescence-activated cell sorting method |
0.0 |
14 |
days |
sham |
saline control group |
111087 |
3196 |
BDIX/OrlCrl |
ratio of survivors to total study population during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
life span trait |
male |
77 days-163 days |
16 |
|
19.0 |
% |
0.0 |
0.0 |
in vivo visual assessment |
0.0 |
100 |
days |
two treatment regimen |
saline control group |
111146 |
3196 |
BDIX/OrlCrl |
percentage of study population developing extra-hepatic metastases during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-142 days |
13 |
|
100.0 |
% |
|
|
necropsy |
0.0 |
0 |
|
|
saline control group |
111132 |
3196 |
BDIX/OrlCrl |
blood CD8 cell count |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD8-positive T cell quantity |
male |
91 days-105 days |
16 |
|
1.17 |
x 10E6 cells/ml |
0.07 |
0.3 |
fluorescence-activated cell sorting method |
0.0 |
28 |
days |
saline control |
saline control group |
111098 |
3196 |
BDIX/OrlCrl |
post-insult time of death due to metastatic liver tumors |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
life span trait |
male |
77 days-142 days |
13 |
median |
78.5 |
d |
3.63 |
13.1 |
necropsy |
0.0 |
14 |
|
saline |
saline control group |
111116 |
3196 |
BDIX/OrlCrl |
percentage of study population developing ascites during a period of time |
DHD/K12/TRb cells (9 X 10E6) (for 0.1 hours) and splenectomy then 0.9% sodium chloride solution (2 ml) (for 7 days) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
peritoneum integrity trait |
male |
77 days-142 days |
13 |
|
100.0 |
% |
0.0 |
0.0 |
necropsy |
0.0 |
0 |
|
|
saline control group |
111124 |
3196 |
BDIX/OrlCrl |
blood CD4 cell count |
0.9% sodium chloride solution (2 ml) |
Silecchia G, etal., Cancer Immunol Immunother. 1999 Jul;48(4):172-8. doi: 10.1007/s002620050562. |
CD4-positive T cell quantity |
male |
63 days-77 days |
16 |
|
2.06 |
x 1000 cells/ul |
0.17 |
0.67 |
fluorescence-activated cell sorting method |
0.0 |
0 |
days |
baseline |
baseline saline control group |
111106 |
3196 |