SS-Chr YBN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
24 |
|
6.19 |
ml/min/g |
0.31 |
1.5 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46267 |
461 |
SS-Chr YBN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
16 |
post-ischemic value/pre-ischemic value x 100% |
84.98 |
% |
7.21 |
28.83 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44984 |
461 |
SS-Chr YBN/Mcwi |
left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
24 |
|
139.37 |
mmHg |
4.46 |
21.86 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45794 |
461 |
SS-Chr YBN/Mcwi |
time to onset of heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
29 |
|
907.97 |
s |
40.12 |
216.05 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49364 |
461 |
SS-Chr YBN/Mcwi |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
26 |
|
938.46 |
s |
27.41 |
139.76 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50185 |
461 |
SS-Chr YBN/Mcwi |
time to peak heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
29 |
|
1174.9 |
s |
31.95 |
172.08 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50292 |
461 |
SS-Chr YBN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
25 |
post-ischemic value/pre-ischemic value x 100% |
68.76 |
% |
3.78 |
18.92 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48821 |
461 |
SS-Chr YBN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
25 |
|
17.28 |
% |
2.63 |
13.15 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49462 |
461 |
SS-Chr YBN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
24 |
|
55.14 |
mmHg |
2.34 |
11.48 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47767 |
461 |
SS-Chr YBN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
26 |
|
9.97 |
ml/min/g |
0.36 |
1.85 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46935 |
461 |
SS-Chr YBN/Mcwi |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
26 |
|
57.31 |
mmHg |
2.73 |
13.93 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48099 |
461 |
SS-Chr YBN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
26 |
|
248.32 |
beats/min |
10.82 |
55.17 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48263 |
461 |
SS-Chr YBN/Mcwi |
left ventricular diastolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
24 |
|
4.91 |
mmHg |
0.22 |
1.1 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47262 |
461 |
SS-Chr YBN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
29 |
|
5.8 |
ml/min/g |
0.47 |
2.53 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
44783 |
461 |
SS-Chr YBN/Mcwi |
left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
28 |
|
94.9 |
mmHg |
3.01 |
15.95 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49953 |
461 |
SS-Chr YBN/Mcwi |
left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
19 |
|
132.35 |
mmHg |
5.04 |
21.96 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48689 |
461 |
SS-Chr YBN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
24 |
|
53.26 |
mmHg |
4.13 |
20.23 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47977 |
461 |
SS-Chr YBN/Mcwi |
left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
28 |
|
42.56 |
mmHg |
4.23 |
22.39 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45335 |
461 |
SS-Chr YBN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
12 |
|
122.45 |
mmHg |
5.02 |
17.4 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
|
46816 |
461 |
SS-Chr YBN/Mcwi |
percent change in left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
24 |
post-ischemic value/pre-ischemic value x 100% |
31.94 |
% |
3.61 |
17.69 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48592 |
461 |
SS-Chr YBN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
19 |
|
5.54 |
mmHg |
0.15 |
0.66 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49243 |
461 |
SS-Chr YBN/Mcwi |
left ventricular diastolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
29 |
|
53.02 |
mmHg |
2.78 |
14.97 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46482 |
461 |
SS-Chr YBN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
29 |
|
0.36 |
IU/g |
0.03 |
0.18 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47480 |
461 |
SS-Chr YBN/Mcwi |
heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
28 |
|
235.7 |
beats/min |
6.26 |
33.1 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47647 |
461 |
SS-Chr YBN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
28 |
|
11.9 |
ml/min/g |
0.51 |
2.72 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46718 |
461 |
SS-Chr YBN/Mcwi |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
26 |
post-ischemic value/pre-ischemic value x 100% |
84.2 |
% |
8.13 |
41.48 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48472 |
461 |
SS-Chr YBN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
24 |
|
216.67 |
beats/min |
15.8 |
77.42 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49011 |
461 |
SS-Chr YBN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
26 |
|
0.27 |
IU/g |
0.03 |
0.17 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47344 |
461 |
SS-Chr YBN/Mcwi |
percent change in heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
29 |
post-ischemic value/pre-ischemic value x 100% |
86.66 |
% |
4.99 |
26.85 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48360 |
461 |
SS-Chr YBN/Mcwi |
heart contraction pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
29 |
|
45.52 |
mmHg |
2.58 |
13.88 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50062 |
461 |
SS-Chr YBN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
29 |
|
14.73 |
% |
2.34 |
12.61 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49763 |
461 |
SS-Chr YBN/Mcwi |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
26 |
|
1140.77 |
s |
29.68 |
151.34 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46614 |
461 |
SS-Chr YBN/Mcwi |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
29 |
post-ischemic value/pre-ischemic value x 100% |
47.98 |
% |
3.14 |
16.93 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47142 |
461 |
SS-Chr YBN/Mcwi |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
12 |
post-ischemic value/pre-ischemic value x 100% |
43.46 |
% |
5.88 |
20.38 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46385 |
461 |
SS-Chr YBN/Mcwi |
heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
28 |
|
203.53 |
beats/min |
7.7 |
40.73 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45213 |
461 |
SS-Chr YBN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
24 |
|
108.39 |
mmHg |
4.05 |
19.82 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44881 |
461 |
SS-Chr YBN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
26 |
post-ischemic value/pre-ischemic value x 100% |
57.77 |
% |
4.58 |
23.34 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46131 |
461 |
SS-Chr YBN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
16 |
|
126.9 |
mmHg |
4.85 |
19.4 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45570 |
461 |
SS-Chr YBN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
4 |
|
46.09 |
IU/g |
4.96 |
9.92 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
48891 |
461 |