Phenominer Database Results (12 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Record ID Study ID
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 4 61.25 % 14.67 29.34 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62627 528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 1 8.11 E-7mole wire myography using a Digi-Med tissue force analysis system with force transducer 0 63026 528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 4 -6.8 null 0.15 0.3 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62850 528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 1 -6.09 null wire myography using a Digi-Med tissue force analysis system with force transducer 0 62849 528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 1 18.0 % wire myography using a Digi-Med tissue force analysis system with force transducer 0 62626 528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 3 0.01 umol/l 0.0 0.0 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62772 528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 1 -8.05 null wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter 63094 528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 3 -8.05 null 0.1 0.17 wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter 63095 528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 1 1.49 g/mg wire myography using a Digi-Med tissue force analysis system with force transducer 0 63163 528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 1 0.01 umol/l wire myography using a Digi-Med tissue force analysis system with force transducer 0 62771 528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 4 1.88 E-7mole 0.57 1.14 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63027 528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 4 1.14 g/mg 0.19 0.37 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63164 528