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PhenoMiner Database Result        View data table  |  Download data table  |  View expanded data table        


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Experimental Conditions

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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1Condition 2aCondition 2bCondition 3aCondition 3b
2maximum contractile force per wet weight of aortaF344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwifemale0.65g/mgcontrolled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)63169controlled sodium content diet (4 %) (for 14 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
3maximum contractile force per wet weight of aortaF344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwimale0.58g/mgcontrolled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)63165controlled sodium content diet (4 %) (for 14 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
2concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwifemale2.925E-7molecontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)63032controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
2concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwimale0.769E-7molecontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)63028controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
2logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwifemale-8.432controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)63100controlled sodium content diet (4 %) (for 14 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
3logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwimale-8.0257controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)63096controlled sodium content diet (4 %) (for 14 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
2acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselF344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwifemale26.5%controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)62632controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
2acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselF344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwimale95.5%controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)62628controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
2logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwifemale-6.556controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)62855controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
2logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwimale-7.131controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)62851controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
2concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwifemale0.0044umol/lcontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)62777controlled sodium content diet (4 %) (for 14 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
3concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwimale0.0106umol/lcontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)62773controlled sodium content diet (4 %) (for 14 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)