FHH-Chr 7BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
-6.96 |
null |
0.07 |
0.22 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56970 |
522 |
FHH-Chr 7BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
1.6 |
E-7mole |
0.35 |
1.06 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55951 |
522 |
FHH-Chr 7BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
14 |
1.59 |
E-7mole |
0.11 |
0.42 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55959 |
522 |
FHH-Chr 7BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
1.21 |
E-7mole |
0.18 |
0.57 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56575 |
522 |
FHH-Chr 7BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
9 |
1.05 |
E-7mole |
0.12 |
0.36 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56583 |
522 |
FHH-Chr 7BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
9 |
82.44 |
% |
6.48 |
19.45 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
54843 |
522 |
FHH-Chr 7BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
65.33 |
% |
8.25 |
24.76 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
57281 |
522 |
FHH-Chr 7BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
14 |
71.43 |
% |
4.14 |
15.5 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
57289 |
522 |
FHH-Chr 7BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
14 |
-6.81 |
null |
0.03 |
0.11 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55690 |
522 |
FHH-Chr 7BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
70.6 |
% |
5.09 |
16.11 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
54835 |
522 |
FHH-Chr 7BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
9 |
-7.0 |
null |
0.06 |
0.17 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56978 |
522 |
FHH-Chr 7BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
-6.87 |
null |
0.09 |
0.26 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55682 |
522 |