BN/NHsdMcwi |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
20 |
-8.63 |
null |
0.09 |
0.4 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56040 |
522 |
BN/NHsdMcwi |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
19 |
99.37 |
% |
0.31 |
1.34 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56487 |
522 |
BN/NHsdMcwi |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
19 |
0.03 |
10E-7mol/l |
0.01 |
0.04 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55757 |
522 |
BN/NHsdMcwi |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
20 |
0.02 |
10E-7mol/l |
0.0 |
0.01 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55758 |
522 |
BN/NHsdMcwi |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
20 |
99.2 |
% |
0.44 |
1.99 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56327 |
522 |
BN/NHsdMcwi |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
16 |
-8.92 |
null |
0.07 |
0.29 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56041 |
522 |
BN/NHsdMcwi |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
19 |
-8.78 |
null |
0.08 |
0.36 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
54631 |
522 |
BN/NHsdMcwi |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
20 |
98.45 |
% |
0.64 |
2.86 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56488 |
522 |
BN/NHsdMcwi |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
20 |
0.04 |
10E-7mol/l |
0.01 |
0.04 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56252 |
522 |
BN/NHsdMcwi |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
16 |
0.02 |
10E-7mol/l |
0.0 |
0.02 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56253 |
522 |
BN/NHsdMcwi |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
20 |
-8.81 |
null |
0.05 |
0.21 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
54632 |
522 |
BN/NHsdMcwi |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
16 |
99.19 |
% |
0.38 |
1.52 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56328 |
522 |