FHH-Chr 7BN/Mcwi |
time to onset of heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
10 |
|
1013.7 |
s |
37.05 |
117.17 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49375 |
461 |
FHH-Chr 7BN/Mcwi |
heart contraction pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
10 |
|
32.8 |
mmHg |
2.61 |
8.24 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50073 |
461 |
FHH-Chr 7BN/Mcwi |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
10 |
|
1048.5 |
s |
47.75 |
150.99 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50196 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular diastolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
|
45.31 |
mmHg |
3.5 |
11.06 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46493 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
81.14 |
% |
3.08 |
9.73 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48832 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
38.51 |
mmHg |
4.28 |
13.54 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47783 |
461 |
FHH-Chr 7BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
10 |
|
20.84 |
IU/g |
1.94 |
6.12 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46008 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
113.01 |
% |
4.91 |
15.53 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45000 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
39.21 |
% |
5.97 |
18.87 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47158 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
75.75 |
% |
7.89 |
24.96 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46396 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
41.23 |
mmHg |
6.35 |
20.07 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45351 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
|
55.73 |
mmHg |
4.83 |
15.26 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47988 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
54.47 |
mmHg |
2.98 |
9.42 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47993 |
461 |
FHH-Chr 7BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
10 |
|
13.26 |
IU/g |
2.44 |
7.71 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46014 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
72.35 |
% |
5.54 |
17.53 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46401 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
100.99 |
% |
7.01 |
22.17 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44995 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
|
56.92 |
mmHg |
5.94 |
18.77 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45346 |
461 |
FHH-Chr 7BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
female |
49 days-63 days |
10 |
|
3.66 |
% |
1.3 |
4.1 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49774 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
86.82 |
% |
9.05 |
28.6 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48837 |
461 |
FHH-Chr 7BN/Mcwi |
time to onset of heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
10 |
|
893.2 |
s |
72.32 |
228.71 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49380 |
461 |
FHH-Chr 7BN/Mcwi |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
|
1236.0 |
s |
56.59 |
178.96 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46625 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
40.61 |
% |
8.64 |
27.32 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48608 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
|
82.3 |
mmHg |
6.22 |
19.66 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44892 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
80.08 |
% |
3.79 |
11.98 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48483 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
86.6 |
% |
3.66 |
11.56 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48488 |
461 |
FHH-Chr 7BN/Mcwi |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
10 |
|
30.7 |
mmHg |
3.15 |
9.97 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48110 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
|
26.57 |
mmHg |
5.83 |
18.43 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47778 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
92.98 |
mmHg |
4.78 |
15.12 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44897 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
71.83 |
% |
4.82 |
15.24 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46147 |
461 |
FHH-Chr 7BN/Mcwi |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
10 |
|
969.6 |
s |
18.07 |
57.13 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50201 |
461 |
FHH-Chr 7BN/Mcwi |
time to peak heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
|
1261.7 |
s |
43.13 |
136.4 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50303 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
46.77 |
% |
4.39 |
13.87 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48603 |
461 |
FHH-Chr 7BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
9 |
|
29.8 |
IU/g |
1.7 |
5.11 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
48906 |
461 |
FHH-Chr 7BN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
|
208.46 |
beats/min |
8.49 |
26.85 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49022 |
461 |
FHH-Chr 7BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
female |
49 days-63 days |
10 |
|
8.79 |
% |
2.88 |
9.1 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49473 |
461 |
FHH-Chr 7BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
10 |
|
6.3 |
% |
1.67 |
5.3 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49779 |
461 |
FHH-Chr 7BN/Mcwi |
time to peak heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
|
1184.9 |
s |
46.01 |
145.49 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50308 |
461 |
FHH-Chr 7BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
|
4.29 |
ml/min/g |
0.35 |
1.11 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
44799 |
461 |
FHH-Chr 7BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
10 |
|
6.43 |
ml/min/g |
0.5 |
1.59 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46278 |
461 |
FHH-Chr 7BN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
|
223.98 |
beats/min |
8.62 |
27.25 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49027 |
461 |
FHH-Chr 7BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
|
6.93 |
ml/min/g |
0.58 |
1.82 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46283 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
80.76 |
% |
5.14 |
16.26 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48371 |
461 |
FHH-Chr 7BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
10 |
|
5.42 |
ml/min/g |
0.48 |
1.53 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
44794 |
461 |
FHH-Chr 7BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
10 |
|
9.36 |
% |
2.23 |
7.06 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49478 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
95.33 |
mmHg |
5.64 |
17.82 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49969 |
461 |
FHH-Chr 7BN/Mcwi |
heart contraction pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
10 |
|
35.8 |
mmHg |
3.26 |
10.29 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50078 |
461 |
FHH-Chr 7BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
10 |
|
32.54 |
IU/g |
1.66 |
5.24 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
48910 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
|
102.23 |
mmHg |
4.37 |
13.81 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49964 |
461 |
FHH-Chr 7BN/Mcwi |
left ventricular diastolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
54.1 |
mmHg |
2.82 |
8.9 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46498 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
62.81 |
% |
7.14 |
22.59 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46142 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
41.32 |
% |
2.69 |
8.51 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47153 |
461 |
FHH-Chr 7BN/Mcwi |
percent change in heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
82.31 |
% |
3.97 |
12.54 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48376 |
461 |
FHH-Chr 7BN/Mcwi |
heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
|
199.74 |
beats/min |
14.67 |
46.38 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45224 |
461 |
FHH-Chr 7BN/Mcwi |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
10 |
|
35.0 |
mmHg |
2.61 |
8.26 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48115 |
461 |
FHH-Chr 7BN/Mcwi |
heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
|
210.62 |
beats/min |
11.76 |
37.17 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45229 |
461 |
FHH-Chr 7BN/Mcwi |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
|
1177.4 |
s |
25.43 |
80.41 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46630 |
461 |