FHH-Chr 10BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
8 |
|
18.94 |
IU/g |
2.28 |
6.46 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
48855 |
461 |
FHH-Chr 10BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
7 |
|
6.51 |
ml/min/g |
2.47 |
6.54 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46194 |
461 |
FHH-Chr 10BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
6 |
|
6.06 |
ml/min/g |
1.4 |
3.42 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46200 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
80.61 |
% |
3.52 |
9.95 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48294 |
461 |
FHH-Chr 10BN/Mcwi |
arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
8 |
|
5.2 |
ml/min/g |
0.62 |
1.76 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
44717 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
|
36.23 |
mmHg |
7.16 |
20.26 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47694 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
5 |
|
74.19 |
mmHg |
6.87 |
15.37 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44814 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
54.27 |
% |
10.24 |
28.96 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46312 |
461 |
FHH-Chr 10BN/Mcwi |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
6 |
|
23.83 |
mmHg |
2.15 |
5.27 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48032 |
461 |
FHH-Chr 10BN/Mcwi |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
6 |
|
1018.0 |
s |
54.35 |
133.14 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50118 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
4 |
|
72.99 |
mmHg |
13.33 |
26.65 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49881 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
8 |
|
79.11 |
mmHg |
6.71 |
18.99 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49887 |
461 |
FHH-Chr 10BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
9 |
|
4.73 |
% |
0.92 |
2.76 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49697 |
461 |
FHH-Chr 10BN/Mcwi |
time to onset of heart contraction |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
9 |
|
909.22 |
s |
50.21 |
150.64 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49298 |
461 |
FHH-Chr 10BN/Mcwi |
heart contraction pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
9 |
|
23.0 |
mmHg |
2.84 |
8.51 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49996 |
461 |
FHH-Chr 10BN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
6 |
|
232.47 |
beats/min |
50.46 |
123.6 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48944 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular diastolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
8 |
|
41.62 |
mmHg |
3.95 |
11.17 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46416 |
461 |
FHH-Chr 10BN/Mcwi |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
9 |
|
1200.33 |
s |
63.31 |
189.93 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46541 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
46.95 |
% |
6.33 |
17.9 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48526 |
461 |
FHH-Chr 10BN/Mcwi |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
9 |
|
24.49 |
mmHg |
2.94 |
8.82 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48026 |
461 |
FHH-Chr 10BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
6 |
|
7.8 |
% |
2.27 |
5.57 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49395 |
461 |
FHH-Chr 10BN/Mcwi |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
9 |
|
1044.89 |
s |
65.9 |
197.7 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50112 |
461 |
FHH-Chr 10BN/Mcwi |
time to onset of heart contraction |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
4 |
|
773.25 |
s |
145.26 |
290.53 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49292 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
4 |
post-ischemic value/pre-ischemic value x 100% |
49.86 |
% |
5.11 |
10.21 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48520 |
461 |
FHH-Chr 10BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
8 |
|
15.03 |
IU/g |
2.39 |
6.75 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
45972 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
5 |
|
37.18 |
mmHg |
4.9 |
10.96 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47700 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
5 |
post-ischemic value/pre-ischemic value x 100% |
99.83 |
% |
8.35 |
18.68 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44917 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
6 |
post-ischemic value/pre-ischemic value x 100% |
70.44 |
% |
6.3 |
15.43 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46065 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
6 |
post-ischemic value/pre-ischemic value x 100% |
117.78 |
% |
23.99 |
58.77 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48405 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular diastolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
4 |
|
35.44 |
mmHg |
11.2 |
22.4 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46410 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
|
37.89 |
mmHg |
7.98 |
22.56 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47904 |
461 |
FHH-Chr 10BN/Mcwi |
arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
4 |
|
8.54 |
ml/min/g |
1.1 |
2.21 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
44711 |
461 |
FHH-Chr 10BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
female |
49 days-63 days |
3 |
|
5.22 |
% |
2.0 |
3.46 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49691 |
461 |
FHH-Chr 10BN/Mcwi |
time to peak heart contraction |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
4 |
|
1000.25 |
s |
167.56 |
335.11 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50220 |
461 |
FHH-Chr 10BN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
8 |
|
220.55 |
beats/min |
25.28 |
71.49 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48938 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
4 |
post-ischemic value/pre-ischemic value x 100% |
86.78 |
% |
10.27 |
20.55 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48749 |
461 |
FHH-Chr 10BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
6 |
|
18.13 |
IU/g |
2.51 |
6.15 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
48865 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
4 |
post-ischemic value/pre-ischemic value x 100% |
85.5 |
% |
9.75 |
19.5 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48288 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
98.28 |
% |
4.19 |
11.86 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44911 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
75.74 |
% |
11.64 |
32.92 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46059 |
461 |
FHH-Chr 10BN/Mcwi |
heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
4 |
|
173.36 |
beats/min |
23.58 |
47.17 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45141 |
461 |
FHH-Chr 10BN/Mcwi |
heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
8 |
|
180.28 |
beats/min |
12.05 |
34.07 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45147 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
4 |
post-ischemic value/pre-ischemic value x 100% |
66.0 |
% |
4.33 |
8.66 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47070 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
7 |
post-ischemic value/pre-ischemic value x 100% |
55.33 |
% |
5.02 |
13.28 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47076 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
8 |
|
37.48 |
mmHg |
5.81 |
16.42 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45269 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
5 |
|
37.01 |
mmHg |
3.26 |
7.3 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47910 |
461 |
FHH-Chr 10BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
female |
49 days-63 days |
9 |
|
12.24 |
% |
1.98 |
5.93 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49389 |
461 |
FHH-Chr 10BN/Mcwi |
heart contraction pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
4 |
|
18.25 |
mmHg |
6.65 |
13.3 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49990 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
92.43 |
% |
4.09 |
11.57 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48755 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
5 |
post-ischemic value/pre-ischemic value x 100% |
54.88 |
% |
5.5 |
12.31 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46318 |
461 |
FHH-Chr 10BN/Mcwi |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
98.71 |
% |
11.13 |
31.49 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48399 |
461 |
FHH-Chr 10BN/Mcwi |
time to peak heart contraction |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
|
1145.33 |
s |
43.54 |
130.62 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50226 |
461 |
FHH-Chr 10BN/Mcwi |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
6 |
|
1209.83 |
s |
63.33 |
155.12 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46547 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
4 |
|
37.55 |
mmHg |
3.04 |
6.07 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45263 |
461 |
FHH-Chr 10BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
4 |
|
16.85 |
IU/g |
1.82 |
3.65 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
45965 |
461 |
FHH-Chr 10BN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
|
74.12 |
mmHg |
7.81 |
22.09 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44808 |
461 |