Phenominer Database Results (221 results)

 

Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Individual Records Method Method Duration Post Insult Time Value Experiment Notes Record ID Study ID
SS-Chr 18BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 13 9.69 IU/g 1.44 5.18 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49829 461
SS-Chr 20BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 5.33 IU/g 1.09 3.44 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49830 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 14.49 IU/g 1.35 4.27 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49834 461
SS-Chr 18BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 15 10.44 IU/g 1.18 4.56 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49835 461
SHR/NCrl heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 6.46 IU/g 0.89 2.68 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49839 461
BN/NHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 7.39 IU/g 0.95 2.84 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49846 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 9.75 IU/g 1.75 5.24 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45488 461
FHH-Chr 10BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 18.94 IU/g 2.28 6.46 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48855 461
FHH-Chr 10BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 6 18.13 IU/g 2.51 6.15 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48865 461
SS-Chr 3BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 14.3 IU/g 1.82 5.14 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48880 461
FHH-Chr YBN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 19.68 IU/g 2.85 9.02 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48890 461
SS-Chr 11BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 35.54 IU/g 2.07 6.55 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48892 461
SS-Chr 1BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 21.29 IU/g 2.1 6.3 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48894 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 16.5 IU/g 1.71 5.13 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48896 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 18.41 IU/g 2.25 6.38 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48901 461
FHH-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 4 15.19 IU/g 1.83 3.66 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45952 461
FHH-Chr 13BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 26.68 IU/g 3.46 9.8 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45981 461
SS-Chr 11BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 14 23.08 IU/g 4.09 15.31 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45993 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 13.64 IU/g 2.07 5.85 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45997 461
SS-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 18 34.31 IU/g 2.47 10.46 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46006 461
F344/DuCrl heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 5.03 IU/g 0.73 2.3 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47176 461
SS-Chr 18BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 6 10.17 IU/g 0.68 1.66 isolated perfused heart effluent collection 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45113 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 3 0.89 IU/g 0.61 1.06 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47177 461
WKY/NCrl heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 7.57 IU/g 0.74 2.33 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47179 461
SHR/NCrl heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 15 8.01 IU/g 0.91 3.52 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45707 461
FHH-Chr 2BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 7.47 IU/g 1.32 3.96 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45953 461
SS-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 19 27.87 IU/g 2.62 11.43 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45959 461
FHH-Chr 10BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 4 16.85 IU/g 1.82 3.65 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45965 461
FHH-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 17 19.74 IU/g 2.1 8.67 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45967 461
FHH-Chr 19BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 20.36 IU/g 0.84 2.64 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45975 461
SS-Chr 3BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 18.62 IU/g 3.31 9.36 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45978 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 14 24.75 IU/g 3.07 11.5 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45980 461
BN/NHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 3 34.51 IU/g 7.7 13.34 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46012 461
FHH-Chr 9BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 13.26 IU/g 2.5 7.51 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46015 461
LEW/Crl heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 20.63 IU/g 4.52 14.3 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49621 461
SS-Chr 7BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 3 47.89 IU/g 4.49 7.78 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48862 461
SS-Chr 15BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 30.41 IU/g 3.79 11.38 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48873 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 24 29.51 IU/g 3.22 15.8 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48893 461
SS-Chr 1BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 13.59 IU/g 1.45 4.11 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48897 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 4 8.62 IU/g 0.35 0.69 isolated perfused heart effluent collection 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 49815 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 42 10.45 IU/g 1.03 6.68 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49831 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 13.94 IU/g 2.2 6.23 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49832 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 4 6.52 IU/g 1.0 2.0 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49833 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 9.56 IU/g 1.64 4.91 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49838 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 5.44 IU/g 0.84 2.66 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49840 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 18.6 IU/g 3.24 10.24 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49841 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 7 6.99 IU/g 0.85 2.26 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49845 461
FHH-Chr 5BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 20.16 IU/g 1.41 4.45 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48847 461
SS-Chr 10BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 30.19 IU/g 3.69 11.07 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48851 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 7 28.22 IU/g 2.45 6.48 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48870 461
FHH-Chr 3BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 1 6.31 IU/g isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48872 461
FHH-Chr 13BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 24.13 IU/g 1.73 5.18 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48878 461
SS-Chr 13BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 30.61 IU/g 3.05 9.15 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48888 461
FHH-Chr 5BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 13.79 IU/g 1.7 4.8 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45954 461
FHH-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 6 15.63 IU/g 1.38 3.38 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45962 461
FHH-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 20 29.2 IU/g 1.64 7.34 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45966 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 15 22.98 IU/g 2.94 11.39 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45976 461
FHH-Chr 3BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 5 10.85 IU/g 1.15 2.56 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45977 461
SS-Chr 11BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 24.59 IU/g 4.83 15.27 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45989 461
SS-Chr 19BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 7 15.8 IU/g 1.18 3.13 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46003 461
FHH-Chr 11BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 12.22 IU/g 1.74 4.93 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46005 461
SS-Chr 12BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 7 8.76 IU/g 1.36 3.61 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46010 461
SS-Chr 18BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 5 9.03 IU/g 1.64 3.67 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45700 461
SHR/NCrl heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 8.72 IU/g 0.86 2.72 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45704 461
BN/NHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 11.48 IU/g 0.82 2.59 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45710 461
SS-Chr XBN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 11 28.39 IU/g 2.19 7.26 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46013 461
LEW/Crl heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 10.97 IU/g 0.93 2.95 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47178 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 2 0.31 IU/g 0.04 0.06 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47180 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 5 4.61 IU/g 1.58 3.53 isolated perfused heart effluent collection 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45117 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 14.25 IU/g 2.36 6.66 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 45370 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 7 1.71 IU/g 1.07 2.83 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45695 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 9.43 IU/g 1.35 4.27 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45699 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 6 11.83 IU/g 0.85 2.09 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45703 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 10.85 IU/g 1.23 3.7 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45705 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 6 13.17 IU/g 2.67 6.54 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 45369 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 10.99 IU/g 0.94 2.66 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 45371 461
SS-Chr 5BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 23.95 IU/g 2.61 7.82 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45969 461
FHH-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 20 26.35 IU/g 1.65 7.38 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45973 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 26 26.47 IU/g 2.86 14.59 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45994 461
SS-Chr 1BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 15.96 IU/g 2.56 7.67 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45998 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 11.57 IU/g 1.63 4.9 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46002 461
FHH-Chr 9BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 14.54 IU/g 2.21 6.64 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46009 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 5 13.38 IU/g 5.32 11.9 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 50206 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 8.5 IU/g 1.34 3.79 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 50208 461
SS-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 31.97 IU/g 4.89 14.67 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48848 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 32.53 IU/g 2.99 8.45 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48877 461
FHH-Chr 18BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 25.73 IU/g 1.59 4.76 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48883 461
FHH-Chr 11BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 23.38 IU/g 2.68 7.59 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48900 461
SS-Chr 19BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 23.09 IU/g 2.6 7.8 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48902 461
FHH-Chr 7BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 32.54 IU/g 1.66 5.24 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48910 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 3 0.33 IU/g 0.14 0.24 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49620 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 2 9.2 IU/g 6.45 9.12 isolated perfused heart effluent collection 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 49814 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 5 8.21 IU/g 1.68 3.76 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49837 461
SS-Chr 20BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 17 9.88 IU/g 2.03 8.36 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49844 461
FHH-Chr 9BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 14.21 IU/g 2.31 6.54 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48911 461
SS-Chr 7BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 39.31 IU/g 3.65 10.96 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48857 461
FHH-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 7 18.48 IU/g 2.99 7.9 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48861 461
FHH-Chr XBN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 15.59 IU/g 3.12 9.37 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48863 461
FHH-Chr XBN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 7 9.73 IU/g 1.32 3.48 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48866 461
FHH-Chr 8BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 25.75 IU/g 1.34 4.24 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48868 461
SS-Chr 11BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 28.96 IU/g 2.67 7.55 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48886 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 33.98 IU/g 2.63 7.89 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48899 461
SS-Chr 19BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 22.46 IU/g 3.22 9.66 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48905 461
FHH-Chr 12BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 5 20.8 IU/g 5.77 12.9 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45949 461
FHH-Chr 6BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 11 15.05 IU/g 0.99 3.28 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45956 461
FHH-Chr 5BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 18.72 IU/g 2.37 6.7 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45958 461
FHH-Chr 15BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 6 13.84 IU/g 1.68 4.1 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45960 461
SS-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 4 25.4 IU/g 1.43 2.86 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45964 461
FHH-Chr 13BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 27.79 IU/g 2.7 8.54 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45985 461
FHH-Chr 3BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 14.02 IU/g 2.17 6.14 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45991 461
SS-Chr 20BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 13 8.75 IU/g 1.01 3.65 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45694 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 33 9.64 IU/g 0.9 5.18 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45696 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 3 9.49 IU/g 3.99 6.92 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45698 461
SS-Chr 20BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 15 7.93 IU/g 1.03 3.99 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45708 461
WKY/NCrl heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 6.98 IU/g 0.65 2.04 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47174 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 10.56 IU/g 1.36 4.07 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47415 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 10.41 IU/g 1.62 4.59 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 45364 461
SS-Chr 18BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 5 8.02 IU/g 1.87 4.19 isolated perfused heart effluent collection 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45116 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 6 11.43 IU/g 0.72 1.77 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45697 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 6 13.29 IU/g 2.15 5.27 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 45367 461
FHH-Chr 15BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 16.71 IU/g 2.7 7.63 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45950 461
SS-Chr 5BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 30.89 IU/g 3.64 10.3 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45971 461
FHH-Chr 20BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 20.03 IU/g 3.07 9.21 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45984 461
FHH-Chr 18BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 7 23.98 IU/g 2.79 7.39 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45988 461
SS-Chr 19BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 18.39 IU/g 1.31 3.72 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46007 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 6 7.04 IU/g 0.43 1.06 isolated perfused heart effluent collection 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 49816 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 8.88 IU/g 0.99 3.13 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 50203 461
FHH-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 25.19 IU/g 1.66 4.71 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48867 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 27.61 IU/g 2.28 6.84 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48871 461
FHH-Chr 8BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 27.47 IU/g 1.8 5.7 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48879 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 37 19.01 IU/g 1.11 6.77 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48887 461
SS-Chr YBN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 4 46.09 IU/g 4.96 9.92 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48891 461
FHH-Chr 7BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 29.8 IU/g 1.7 5.11 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48906 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 6 11.67 IU/g 2.31 5.66 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 50209 461
SHR/NCrl heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 5 3.88 IU/g 0.53 1.18 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 50210 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 5 8.69 IU/g 1.31 2.93 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 50211 461
SS-Chr 9BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 14 6.82 IU/g 1.15 4.3 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49836 461
SS-Chr 9BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 14 7.38 IU/g 1.14 4.26 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49842 461
BN/NHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 7.23 IU/g 0.96 2.7 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49847 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 3 0.31 IU/g 0.07 0.12 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49622 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 6 17.99 IU/g 4.36 10.69 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45487 461
SS-Chr 10BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 11 34.18 IU/g 5.29 17.56 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48840 461
FHH-Chr 2BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 6 9.1 IU/g 1.59 3.89 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48842 461
FHH-Chr 5BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 23.16 IU/g 1.55 4.39 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48843 461
FHH-Chr 6BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 21.21 IU/g 1.25 3.75 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48845 461
FHH-Chr 12BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 22.77 IU/g 2.45 6.93 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48849 461
SS-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 28.24 IU/g 1.49 4.73 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48859 461
SS-Chr 3BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 7 16.25 IU/g 2.42 6.41 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48874 461
FHH-Chr 19BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 22.11 IU/g 2.46 7.78 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48876 461
SS-Chr 10BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 41.21 IU/g 2.87 8.6 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45951 461
FHH-Chr 8BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 22.82 IU/g 3.46 10.95 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45974 461
FHH-Chr 19BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 19.42 IU/g 1.53 4.84 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45979 461
FHH-Chr 20BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 18.88 IU/g 1.15 3.44 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45987 461
SS-Chr 1BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 21.45 IU/g 3.7 10.48 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45995 461
SS-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 17 32.71 IU/g 3.25 13.4 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45999 461
FHH-Chr 7BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 20.84 IU/g 1.94 6.12 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46008 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 3 10.97 IU/g 0.8 1.38 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45702 461
SS-Chr 9BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 15 7.21 IU/g 1.45 5.62 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45706 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 5 5.24 IU/g 1.89 4.22 isolated perfused heart effluent collection 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45115 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 18.67 IU/g 2.75 8.26 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 45366 461
F344/DuCrl heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 7.12 IU/g 0.82 2.31 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47181 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 1 4.65 IU/g isolated perfused heart effluent collection 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45114 461
FHH-Chr 8BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 22.8 IU/g 1.36 4.31 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45982 461
FHH-Chr 18BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 5 28.17 IU/g 2.11 4.72 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45986 461
SS-Chr XBN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 20.17 IU/g 2.03 6.09 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45996 461
SS-Chr 12BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 12.57 IU/g 2.32 7.35 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46004 461
FHH-Chr 15BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 14.68 IU/g 1.63 4.62 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48839 461
SS-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 29.5 IU/g 2.65 8.37 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48844 461
FHH-Chr 15BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 7 14.0 IU/g 1.53 4.06 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48850 461
SS-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 29.72 IU/g 1.37 4.32 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48854 461
FHH-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 28.44 IU/g 2.1 6.31 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48856 461
FHH-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 21.8 IU/g 2.06 6.19 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48858 461
SS-Chr 5BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 21.25 IU/g 2.13 6.4 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48864 461
SS-Chr 15BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 25.02 IU/g 2.1 6.65 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48875 461
FHH-Chr 20BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 25.14 IU/g 3.43 10.28 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48881 461
FHH-Chr 18BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 25.4 IU/g 2.75 8.26 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48885 461
FHH-Chr 3BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 7 17.84 IU/g 3.57 9.44 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48889 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 13.15 IU/g 2.12 6.69 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 50202 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 7 8.52 IU/g 1.64 4.34 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 50204 461
SHR/NCrl heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 4 7.68 IU/g 0.46 0.93 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 50205 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 11.84 IU/g 2.13 6.02 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 50207 461
SHR/NCrl heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 6.43 IU/g 0.52 1.47 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 49843 461
FHH-Chr 12BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 26.38 IU/g 3.42 10.8 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48838 461
FHH-Chr 2BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 7 6.34 IU/g 1.97 5.22 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48853 461
FHH-Chr 13BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 7 23.86 IU/g 3.38 8.94 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48882 461
FHH-Chr 20BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 27.22 IU/g 2.48 7.85 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48884 461
SS-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 25.28 IU/g 3.19 9.58 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48898 461
FHH-Chr 11BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 18.55 IU/g 1.08 3.4 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48903 461
FHH-Chr 9BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 6 16.69 IU/g 2.25 5.5 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48907 461
SS-Chr XBN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 21.82 IU/g 2.57 8.12 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48909 461
SS-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 4 19.38 IU/g 0.42 0.83 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45968 461
FHH-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 17 20.0 IU/g 2.15 8.86 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45970 461
FHH-Chr 10BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 15.03 IU/g 2.39 6.75 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45972 461
SS-Chr 3BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 15.78 IU/g 1.02 3.22 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45983 461
FHH-Chr 11BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 11.3 IU/g 1.12 3.55 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46001 461
BN/NHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 4 40.49 IU/g 5.92 11.84 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46011 461
FHH-Chr 7BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 13.26 IU/g 2.44 7.71 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46014 461
SS-Chr 16BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 18.26 IU/g 3.41 9.66 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 45368 461
LEW/Crl heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 9.3 IU/g 1.02 3.05 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47175 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 12 10.31 IU/g 1.37 4.76 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47416 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 6 10.58 IU/g 3.03 7.41 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Dyets 45365 461
SS-Chr 18BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 5 6.93 IU/g 2.76 6.17 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45693 461
SS-Chr 9BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 16 7.93 IU/g 1.33 5.34 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45701 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 5 2.98 IU/g 1.84 4.11 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45709 461
BN/NHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 9.69 IU/g 0.76 2.4 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45711 461
SS-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 15 26.61 IU/g 2.95 11.44 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45955 461
FHH-Chr 6BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 9.75 IU/g 0.99 2.8 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45957 461
SS-Chr 10BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 34.82 IU/g 2.37 6.71 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45961 461
FHH-Chr 2BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 7.1 IU/g 0.77 2.19 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45963 461
FHH/EurMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 38 17.04 IU/g 1.18 7.26 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45990 461
FHH-Chr YBN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 17.9 IU/g 2.2 6.96 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45992 461
SS/JrHsdMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 23.2 IU/g 3.38 10.15 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46000 461
LEW/Crl heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 16.64 IU/g 0.93 2.93 isolated perfused heart effluent collection 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49619 461
FHH-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 7 17.62 IU/g 1.46 3.85 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48841 461
FHH-Chr 6BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 19.43 IU/g 2.09 6.62 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48846 461
FHH-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 6 16.96 IU/g 0.69 1.68 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48852 461
SS-Chr 5BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 21.9 IU/g 2.48 7.45 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48860 461
FHH-Chr 19BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 10 22.82 IU/g 3.15 9.97 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48869 461
SS-Chr XBN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 18.94 IU/g 2.46 7.78 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48895 461
SS-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 25.93 IU/g 1.88 5.64 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48904 461
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 3 40.75 IU/g 5.0 8.67 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48908 461