F344/NRrrc |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
123.12 |
mg/dl |
0.81 |
12.06 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
0 |
min |
|
|
|
65948 |
114 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 15 |
91.8 |
mg/dl |
1.8 |
6.97 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
0 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11428 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
104.4 |
mg/dl |
3.6 |
11.94 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
0 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11430 |
85 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 15 |
86.4 |
mg/dl |
1.8 |
6.97 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
0 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11450 |
85 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 15 |
169.2 |
mg/dl |
5.4 |
20.91 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11458 |
85 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
190.8 |
mg/dl |
9.0 |
29.85 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11460 |
85 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 15 |
286.2 |
mg/dl |
7.2 |
27.89 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11461 |
85 |
WOKW |
blood glucose level area under curve (AUC) |
glucose solution (2 g/kg) |
Kloting I, et al., Biochem Biophys Res Commun 2001 Jun 1;284(1):150-6. |
blood glucose amount |
female |
0 days
| 12 |
11127.27 |
(mg/dl) x min |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
intraperitoneal injection |
60 |
min |
glucose analyser (Medingen ESAT 6660-2, Germany) |
samples taken at 0, 10, 30, 60 minutes |
|
13272 |
251 |
DA/K |
blood glucose level area under curve (AUC) |
glucose solution (2 g/kg) |
Kloting I, et al., Biochem Biophys Res Commun 2001 Jun 1;284(1):150-6. |
blood glucose amount |
female |
0 days
| 12 |
8636.36 |
(mg/dl) x min |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
intraperitoneal injection |
60 |
min |
glucose analyser (Medingen ESAT 6660-2, Germany) |
samples taken at 0, 10, 30, 60 minutes |
|
13274 |
251 |
F344/NSlc |
blood glucose level |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 7 |
157.0 |
mg/dl |
5.21 |
13.78 |
oral glucose tolerance test |
|
0 |
oral dose |
60 |
min |
|
|
|
13159 |
106 |
F344/NHsd |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood glucose amount |
female |
119 days
| 10 |
65.1 |
mg/dl |
3.6 |
11.38 |
plasma glucose analysis |
|
0 |
|
0 |
|
|
|
|
13181 |
107 |
BN.GK-(D8Rat29-D8Got130)/Ox |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
male |
84 days
| 12 |
4.03 |
mU/l |
0.72 |
2.49 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67328 |
66 |
BN/Crl |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
male |
168 days
| 20 |
5.47 |
mU/l |
0.72 |
3.22 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67330 |
66 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
145.8 |
mg/dl |
9.0 |
29.85 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
60 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11435 |
85 |
F344/NCrl |
blood insulin level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood insulin amount |
male |
95 days
| 12 |
180.85 |
mU/l |
74.32 |
257.45 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
|
micrograms/L |
|
13081 |
330 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
367.2 |
mg/dl |
9.0 |
31.18 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
|
|
|
13091 |
330 |
F344.GK-(D1Got250-D1Rat90)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
279.0 |
mg/dl |
9.0 |
31.18 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
|
|
|
13103 |
330 |
BN/CrlCrlj |
blood glucose level |
controlled protein content diet (for 120 days) then fasting (for 9 hours) then glucose solution |
Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. |
blood glucose amount |
male |
120 days
| 5 |
178.1 |
mg/dl |
7.9 |
17.66 |
oral glucose tolerance test |
|
|
glucose challenge |
30 |
min |
glucose dose not specified |
serum glucose |
WBN/Kob rats were studied as a model of pancreatitis and diabetes mellitus |
12908 |
321 |
BN/CrlCrlj |
blood glucose level |
controlled protein content diet (for 120 days) then fasting (for 9 hours) then glucose solution |
Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. |
blood glucose amount |
male |
120 days
| 5 |
211.3 |
mg/dl |
17.9 |
40.03 |
oral glucose tolerance test |
|
|
glucose challenge |
60 |
min |
glucose dose not specified |
serum glucose |
WBN/Kob rats were studied as a model of pancreatitis and diabetes mellitus |
12909 |
321 |
F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65 days
| 15 |
0.07 |
mg/dl |
0.01 |
0.04 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
|
67625 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 11 |
0.01 |
mg/dl |
0.0 |
0.01 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
0 |
min |
|
|
|
67631 |
85 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 20 |
334.8 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
|
67648 |
85 |
F344/NRrrc |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 7 |
104.0 |
mg/dl |
6.1 |
16.14 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
0 |
min |
|
|
|
68070 |
836 |
OLETF |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 14 |
344.3 |
mg/dl |
8.5 |
31.8 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
30 |
min |
|
|
|
68074 |
836 |
OLETF |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 14 |
352.8 |
mg/dl |
8.6 |
32.18 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
60 |
min |
|
|
|
68077 |
836 |
DA/K |
blood glucose level area under curve (AUC) |
glucose solution (2 g/kg) |
Kovacs P, et al., Biochem Biophys Res Commun 2000 Mar 24;269(3):660-5. |
blood glucose amount |
not specified |
196 days-224 days |
12 |
8872.73 |
(mg/dl) x min |
335.91 |
1163.64 |
intraperitoneal glucose tolerance test |
|
0.0 |
IPGTT |
60 |
min |
|
|
|
96851 |
1123 |
GK/MolTac |
blood glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. |
blood glucose amount |
male |
70 days-77 days |
6 |
209.0 |
mg/dl |
4.9 |
12.0 |
oral glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
103804 |
2864 |
SD-Lepem1Sage-/- |
serum glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) (for 1 hours) |
Vaira S, et al., Endocrinology. 2012 Nov;153(11):5622-8. doi: 10.1210/en.2012-1462. Epub 2012 Sep 4. |
blood glucose amount |
not specified |
42 days
| 10 |
253.9 |
mg/dl |
35.8 |
113.21 |
intraperitoneal glucose tolerance test |
|
0.0 |
glucose inj |
60 |
min |
|
|
|
104538 |
2969 |
W/Jpe |
blood glucose level |
fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) |
Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. |
blood glucose amount |
male |
540 days
| 20 |
116.3 |
mg/dl |
4.0 |
17.89 |
intraperitoneal glucose tolerance test |
|
0.0 |
|
120 |
min |
|
|
|
108009 |
3108 |
GK/Jpe |
blood glucose level |
controlled cholesterol content diet (1.25 %) (for 90 days) and controlled cocoa butter content diet (7.5 %) (for 90 days) then lipoic acid (50 mg/kg) then fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) |
Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. |
blood glucose amount |
male |
540 days
| 10 |
365.6 |
mg/dl |
9.5 |
30.04 |
intraperitoneal glucose tolerance test |
|
0.0 |
|
120 |
min |
|
|
|
108013 |
3108 |
GK |
pancreatic islet insulin release measurement |
controlled dehydroepiandrosterone content diet (0.2 %) (for 28 days) then glucose solution (2.8 mmol/l) (for 1.5 hours) |
Ladriere L, et al., Cell Biochem Funct. 1997 Dec;15(4):287-92. doi: 10.1002/(SICI)1099-0844(199712)15:4<287::AID-CBF753>3.0.CO;2-X. |
pancreatic beta cell physiology trait |
male |
73 days
| 33 |
18.3 |
uU/islet/90min |
1.9 |
10.91 |
radioimmunoassay |
|
0.0 |
glucose |
90 |
min |
ex vivo incubation |
|
|
110628 |
3179 |
GK |
pancreatic islet insulin release measurement |
glucose solution (16.7 mmol/l) (for 1.5 hours) |
Ladriere L, et al., Cell Biochem Funct. 1997 Dec;15(4):287-92. doi: 10.1002/(SICI)1099-0844(199712)15:4<287::AID-CBF753>3.0.CO;2-X. |
pancreatic beta cell physiology trait |
female |
73 days
| 33 |
124.0 |
uU/islet/90min |
6.0 |
34.47 |
radioimmunoassay |
|
0.0 |
glucose |
90 |
min |
ex vivo incubation |
|
|
110633 |
3179 |
GK |
pancreatic islet insulin release measurement |
controlled dehydroepiandrosterone content diet (0.2 %) (for 28 days) then glucose solution (16.7 mmol/l) (for 1.5 hours) |
Ladriere L, et al., Cell Biochem Funct. 1997 Dec;15(4):287-92. doi: 10.1002/(SICI)1099-0844(199712)15:4<287::AID-CBF753>3.0.CO;2-X. |
pancreatic beta cell physiology trait |
female |
73 days
| 33 |
83.5 |
uU/islet/90min |
5.4 |
31.02 |
radioimmunoassay |
|
0.0 |
glucose |
90 |
min |
ex vivo incubation |
|
|
110634 |
3179 |
W/Jpe |
blood glucose level |
fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) |
Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. |
blood glucose amount |
male |
540 days
| 7 |
117.0 |
mg/dl |
10.8 |
28.57 |
intraperitoneal glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
110865 |
3193 |
GK/Jpe |
blood glucose level |
fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) |
Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. |
blood glucose amount |
male |
540 days
| 7 |
332.1 |
mg/dl |
48.6 |
128.58 |
intraperitoneal glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
110866 |
3193 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level area under curve (AUC) |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
17654.55 |
(mg/dl) x min |
636.36 |
2110.58 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11447 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 11 |
0.05 |
mg/dl |
0.01 |
0.04 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
|
67635 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
252.0 |
mg/dl |
7.2 |
23.88 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11438 |
85 |
F344.GK-(D1Rat175-D1Rat90)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
396.0 |
mg/dl |
10.8 |
37.41 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
|
|
|
13096 |
330 |
F344.GK-(D1Rat83-D1Rat376)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
333.0 |
mg/dl |
7.2 |
24.94 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
|
|
|
13110 |
330 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 15 |
271.8 |
mg/dl |
9.0 |
34.86 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11440 |
85 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
99.0 |
mg/dl |
3.6 |
11.94 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
60 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11457 |
85 |
F344/NSlc |
blood glucose level |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 7 |
134.1 |
mg/dl |
4.7 |
12.44 |
oral glucose tolerance test |
|
0 |
oral dose |
15 |
min |
|
|
|
13157 |
106 |
SDT/Jcl |
blood glucose level |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 5 |
640.6 |
mg/dl |
16.99 |
37.99 |
oral glucose tolerance test |
|
0 |
oral dose |
120 |
min |
|
|
|
13168 |
106 |
F344/NRrrc |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 7 |
124.1 |
mg/dl |
1.6 |
4.23 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
30 |
min |
|
|
|
68073 |
836 |
F344/NRrrc |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 7 |
139.0 |
mg/dl |
2.4 |
6.35 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
90 |
min |
|
|
|
68079 |
836 |
WOKW/K |
blood glucose level area under curve (AUC) |
glucose solution (2 g/kg) |
Kovacs P, et al., Biochem Biophys Res Commun 2000 Mar 24;269(3):660-5. |
blood glucose amount |
not specified |
196 days-224 days |
12 |
11854.55 |
(mg/dl) x min |
456.63 |
1581.82 |
intraperitoneal glucose tolerance test |
|
0.0 |
IPGTT |
60 |
min |
|
|
|
96850 |
1123 |
F344/NRrrc |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
158.4 |
mg/dl |
1.09 |
16.2 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
120 |
min |
|
|
|
65983 |
114 |
GK/MolTac |
blood glucose level |
rosiglitazone (5 mg/kg) (for 23 days) then fasting (for 16 hours) then glucose solution (2 g/kg) |
Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. |
blood glucose amount |
male |
95 days-102 days |
3 |
146.0 |
mg/dl |
3.46 |
6.0 |
oral glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
103806 |
2864 |
BUF/N |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
166.14 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
0 |
min |
|
|
|
65947 |
114 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 15 |
219.6 |
mg/dl |
5.4 |
20.91 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11437 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
88.2 |
mg/dl |
1.8 |
5.97 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
60 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11455 |
85 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
311.4 |
mg/dl |
10.8 |
35.82 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11463 |
85 |
WKY/NHsd |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood glucose amount |
male |
119 days
| 10 |
173.8 |
mg/dl |
5.5 |
17.39 |
intraperitoneal glucose tolerance test |
|
0 |
post glucose injection |
60 |
min |
|
|
|
13173 |
107 |
F344/NHsd |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood glucose amount |
male |
119 days
| 10 |
88.0 |
mg/dl |
3.1 |
9.8 |
plasma glucose analysis |
|
0 |
|
0 |
|
|
|
|
13177 |
107 |
OLETF |
plasma glucose level |
fasting (for 16 hours) then glucose solution (for 0.5 hours) |
Watanabe TK, et al., Genomics 1999 Jun 15;58(3):233-9. |
blood glucose amount |
male |
210 days
| 14 |
344.3 |
mg/dl |
8.5 |
31.8 |
oral glucose tolerance test |
|
0.0 |
glucose challenge |
30 |
min |
|
|
|
12777 |
312 |
BN.GK-(D8Got302-D8Got130)/Ox |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
male |
168 days
| 11 |
104.4 |
mg/dl |
5.4 |
17.91 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
|
0.8 g glucose/kg |
|
67320 |
66 |
BN.GK-(D8Got302-D8Got130)/Ox |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
female |
168 days
| 11 |
104.4 |
mg/dl |
3.6 |
11.94 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
|
0.8 g glucose/kg |
|
67326 |
66 |
BN.GK-(D8Got302-D8Got130)/Ox |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
male |
168 days
| 11 |
3.31 |
mU/l |
0.43 |
1.43 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67332 |
66 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
253.8 |
mg/dl |
12.6 |
41.79 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11439 |
85 |
F344/NCrl |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
246.6 |
mg/dl |
9.0 |
31.18 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
|
|
|
13087 |
330 |
F344.GK-(D1Mgh14-D1Rat90)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
333.0 |
mg/dl |
14.4 |
49.88 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
|
|
|
13106 |
330 |
F344.GK-(D1Rat83-D1Rat376)/Swe |
blood insulin level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood insulin amount |
male |
95 days
| 12 |
178.37 |
mU/l |
9.91 |
34.33 |
intraperitoneal glucose tolerance test |
tail vein |
0 |
post glucose injection |
15 |
min |
|
micrograms/L |
|
13109 |
330 |
F344.GK-(D1Rat83-D1Rat376)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
243.0 |
mg/dl |
9.0 |
31.18 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
|
|
|
13111 |
330 |
BN/CrlCrlj |
serum insulin level |
controlled protein content diet (for 120 days) then fasting (for 9 hours) then glucose solution |
Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. |
blood insulin amount |
male |
120 days
| 5 |
0.0 |
mg/dl |
0.0 |
0.0 |
oral glucose tolerance test |
|
|
glucose challenge |
30 |
min |
glucose dose not specified |
serum glucose |
|
12912 |
321 |
F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65 days
| 15 |
0.03 |
mg/dl |
0.0 |
0.02 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
|
67628 |
85 |
SDT/Jcl |
blood glucose level area under curve (AUC) |
fasting (for 18 hours) then glucose solution (2 g/kg) |
Masuyama T, et al., Biochem Biophys Res Commun 2003 Apr 25;304(1):196-206. |
blood glucose amount |
male |
140 days
| 0 |
37998.0 |
(mg/dl) x min |
1584.0 |
|
oral glucose tolerance test |
|
0.0 |
oral dose |
120 |
min |
|
|
|
67912 |
833 |
BN |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 20 |
124.8 |
mg/dl |
2.3 |
10.29 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
30 |
min |
|
|
|
68072 |
836 |
OLETF |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 14 |
289.9 |
mg/dl |
8.7 |
32.55 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
120 |
min |
|
|
|
68083 |
836 |
GK/MolTac |
blood glucose level |
rosiglitazone (10 mg/kg) (for 23 days) then fasting (for 16 hours) then glucose solution (2 g/kg) |
Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. |
blood glucose amount |
male |
95 days-102 days |
4 |
142.0 |
mg/dl |
4.0 |
8.0 |
oral glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
103807 |
2864 |
GK/MolTac |
blood glucose level |
rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 16 hours) then glucose solution (2 g/kg) |
Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. |
blood glucose amount |
male |
122 days-129 days |
4 |
177.0 |
mg/dl |
5.5 |
11.0 |
oral glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
103809 |
2864 |
GK/MolTac |
blood glucose level |
sodium chloride solution (for 23 days) then control condition (for 20 days) then fasting (for 16 hours) then glucose solution (2 g/kg) |
Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. |
blood glucose amount |
male |
122 days-129 days |
4 |
162.0 |
mg/dl |
14.0 |
28.0 |
oral glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
103808 |
2864 |
NTac:SD |
serum glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) (for 1 hours) |
Vaira S, et al., Endocrinology. 2012 Nov;153(11):5622-8. doi: 10.1210/en.2012-1462. Epub 2012 Sep 4. |
blood glucose amount |
not specified |
42 days
| 10 |
174.3 |
mg/dl |
15.7 |
49.65 |
intraperitoneal glucose tolerance test |
|
0.0 |
glucose inj |
60 |
min |
|
|
|
104537 |
2969 |
SD-Lepem1Sage-/- |
serum glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) (for 2 hours) |
Vaira S, et al., Endocrinology. 2012 Nov;153(11):5622-8. doi: 10.1210/en.2012-1462. Epub 2012 Sep 4. |
blood glucose amount |
not specified |
42 days
| 10 |
136.8 |
mg/dl |
16.7 |
52.81 |
intraperitoneal glucose tolerance test |
|
0.0 |
glucose inj |
60 |
min |
|
|
|
104540 |
2969 |
SD-Lepem1Sage-/- |
serum glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) (for 0.5 hours) |
Vaira S, et al., Endocrinology. 2012 Nov;153(11):5622-8. doi: 10.1210/en.2012-1462. Epub 2012 Sep 4. |
blood glucose amount |
not specified |
70 days
| 10 |
411.6 |
mg/dl |
26.98 |
85.32 |
intraperitoneal glucose tolerance test |
|
0.0 |
glucose inj |
60 |
min |
|
|
|
104542 |
2969 |
NTac:SD |
serum glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) (for 2 hours) |
Vaira S, et al., Endocrinology. 2012 Nov;153(11):5622-8. doi: 10.1210/en.2012-1462. Epub 2012 Sep 4. |
blood glucose amount |
not specified |
70 days
| 10 |
119.7 |
mg/dl |
2.62 |
8.29 |
intraperitoneal glucose tolerance test |
|
0.0 |
glucose inj |
60 |
min |
|
|
|
104545 |
2969 |
GK |
pancreatic islet insulin release measurement |
controlled dehydroepiandrosterone content diet (0.2 %) (for 28 days) then glucose solution (16.7 mmol/l) (for 1.5 hours) |
Ladriere L, et al., Cell Biochem Funct. 1997 Dec;15(4):287-92. doi: 10.1002/(SICI)1099-0844(199712)15:4<287::AID-CBF753>3.0.CO;2-X. |
pancreatic beta cell physiology trait |
male |
73 days
| 32 |
113.3 |
uU/islet/90min |
7.5 |
42.43 |
radioimmunoassay |
|
0.0 |
glucose |
90 |
min |
ex vivo incubation |
|
|
110632 |
3179 |
GK/Jcl |
serum insulin level |
fasting then glucose solution (2 g/kg) (for 0.5 hours) |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood insulin amount |
male |
140 days
| 7 |
0.0 |
mg/dl |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
|
0.0 |
glucose |
30 |
min |
|
|
|
110219 |
3167 |
Jcl:WI |
serum insulin level |
vildagliptin (30 mg/kg/d) (for 92 days) then fasting then glucose solution (2 g/kg) (for 0.5 hours) |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood insulin amount |
male |
140 days
| 7 |
0.0 |
mg/dl |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
|
0.0 |
glucose |
30 |
min |
|
|
|
110220 |
3167 |
GK/Jpe |
blood glucose level |
controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) |
Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. |
blood glucose amount |
male |
540 days
| 7 |
358.2 |
mg/dl |
14.4 |
38.1 |
intraperitoneal glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
110868 |
3193 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 20 |
248.4 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
|
67649 |
85 |
BN/Crl |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
male |
84 days
| 23 |
93.6 |
mg/dl |
1.8 |
8.63 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma glucose analysis |
0.8 g glucose/kg |
|
67315 |
66 |
BN.GK-(D8Got302-D8Got130)/Ox |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
male |
84 days
| 15 |
3.45 |
mU/l |
0.72 |
2.79 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67329 |
66 |
F344.GK-(D1Mgh14-D1Rat90)/Swe |
blood insulin level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood insulin amount |
male |
95 days
| 12 |
156.07 |
mU/l |
22.3 |
77.24 |
intraperitoneal glucose tolerance test |
tail vein |
0 |
post glucose injection |
15 |
min |
|
micrograms/L |
|
13105 |
330 |
F344.GK-(D1Swe4-D1Rat85)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
205.2 |
mg/dl |
10.8 |
37.41 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
|
|
|
13115 |
330 |
F344/DuCrlCrlj |
blood glucose level area under curve (AUC) |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 15 |
12818.18 |
(mg/dl) x min |
218.18 |
845.01 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11467 |
85 |
BN/CrlCrlj |
blood glucose level |
controlled protein content diet (for 120 days) then fasting (for 9 hours) then glucose solution |
Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. |
blood glucose amount |
male |
120 days
| 5 |
154.7 |
mg/dl |
13.8 |
30.86 |
oral glucose tolerance test |
|
|
glucose challenge |
120 |
min |
glucose dose not specified |
serum glucose |
WBN/Kob rats were studied as a model of pancreatitis and diabetes mellitus |
12910 |
321 |
BN |
plasma glucose level |
fasting (for 16 hours) then glucose solution (for 0.5 hours) |
Watanabe TK, et al., Genomics 1999 Jun 15;58(3):233-9. |
blood glucose amount |
male |
210 days
| 20 |
124.8 |
mg/dl |
2.3 |
10.29 |
oral glucose tolerance test |
|
0.0 |
glucose challenge |
30 |
min |
|
|
|
12783 |
312 |
F344/NRrrc |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 7 |
128.0 |
mg/dl |
2.4 |
6.35 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
120 |
min |
|
|
|
68082 |
836 |
OLETF |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 14 |
149.2 |
mg/dl |
3.0 |
11.22 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
0 |
min |
|
|
|
68071 |
836 |
WKY/N |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
138.24 |
mg/dl |
0.79 |
11.7 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
0 |
min |
|
|
|
65946 |
114 |
OLETF |
plasma glucose level |
fasting (for 16 hours) then glucose solution |
Hirashima T, et al., Diabetes Res Clin Pract 1995 Feb;27(2):91-6. |
blood glucose amount |
male |
210 days
| 14 |
289.0 |
mg/dl |
8.55 |
32.0 |
oral glucose tolerance test |
|
0.0 |
oral dose |
120 |
min |
|
|
|
67277 |
729 |
BN.GK-(D8Rat29-D8Got130)/Ox |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
male |
84 days
| 11 |
108.0 |
mg/dl |
3.6 |
11.94 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
|
0.8 g glucose/kg |
|
67316 |
66 |
BN.GK-(D8Rat29-D8Got130)/Ox |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
male |
168 days
| 14 |
97.2 |
mg/dl |
3.6 |
13.47 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
|
0.8 g glucose/kg |
|
67319 |
66 |
BN.GK-(D8Rat29-D8Got130)/Ox |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
female |
84 days
| 10 |
104.4 |
mg/dl |
10.8 |
34.15 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
|
0.8 g glucose/kg |
|
67322 |
66 |
BN.GK-(D8Rat29-D8Got130)/Ox |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
female |
168 days
| 10 |
100.8 |
mg/dl |
1.8 |
5.69 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
|
0.8 g glucose/kg |
|
67325 |
66 |
BN/Crl |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
female |
84 days
| 12 |
4.32 |
mU/l |
0.43 |
1.5 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67333 |
66 |
BN.GK-(D8Rat29-D8Got130)/Ox |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
female |
84 days
| 10 |
6.04 |
mU/l |
1.01 |
3.19 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67334 |
66 |
BN/Crl |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
female |
168 days
| 10 |
7.05 |
mU/l |
1.44 |
4.55 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67336 |
66 |
BN.GK-(D8Rat29-D8Got130)/Ox |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
female |
168 days
| 7 |
4.32 |
mU/l |
0.86 |
2.28 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67337 |
66 |
BN.GK-(D8Got302-D8Got130)/Ox |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
male |
168 days
| 10 |
5.32 |
mU/l |
0.72 |
2.28 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67338 |
66 |
F344/NSlc |
blood glucose level |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 7 |
149.1 |
mg/dl |
4.2 |
11.11 |
oral glucose tolerance test |
|
0 |
oral dose |
30 |
min |
|
|
|
13158 |
106 |
SDT/Jcl |
blood glucose level |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 5 |
705.0 |
mg/dl |
46.77 |
104.58 |
oral glucose tolerance test |
|
0 |
oral dose |
15 |
min |
|
|
|
13164 |
106 |
F344/NHsd |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood glucose amount |
female |
105 days
| 10 |
121.7 |
mg/dl |
5.1 |
16.13 |
intraperitoneal glucose tolerance test |
|
0 |
Post glucose injection |
60 |
min |
|
|
|
13180 |
107 |
OLETF |
plasma glucose level |
fasting (for 16 hours) then glucose solution |
Watanabe TK, et al., Genomics 1999 Jun 15;58(3):233-9. |
blood glucose amount |
male |
210 days
| 14 |
149.2 |
mg/dl |
3.0 |
11.22 |
oral glucose tolerance test |
|
|
glucose challenge |
0 |
min |
|
|
|
12776 |
312 |
BN |
plasma glucose level |
fasting (for 16 hours) then glucose solution |
Watanabe TK, et al., Genomics 1999 Jun 15;58(3):233-9. |
blood glucose amount |
male |
210 days
| 20 |
91.3 |
mg/dl |
1.5 |
6.71 |
oral glucose tolerance test |
|
0.0 |
glucose challenge |
0 |
min |
|
|
|
12779 |
312 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 15 |
86.4 |
mg/dl |
3.6 |
13.94 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11451 |
85 |
F344/NSlc |
blood glucose level area under curve (AUC) |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 7 |
1.8 |
(mg/dl) x min |
0.52 |
1.38 |
oral glucose tolerance test |
|
0 |
oral dose |
0 |
|
trapezoid rule used for calculation |
|
|
11606 |
106 |
WKY/NHsd |
plasma insulin level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood insulin amount |
male |
119 days
| 10 |
64.1 |
mU/l |
9.7 |
30.67 |
intraperitoneal glucose tolerance test |
|
0 |
post glucose injection |
60 |
min |
|
|
|
11612 |
107 |
F344/NHsd |
plasma insulin level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood insulin amount |
male |
119 days
| 10 |
43.0 |
mU/l |
4.6 |
14.55 |
intraperitoneal glucose tolerance test |
|
0 |
post glucose injection |
60 |
min |
|
|
|
11613 |
107 |
WKY/NHsd |
plasma insulin level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood insulin amount |
female |
119 days
| 10 |
20.0 |
mU/l |
2.5 |
7.91 |
intraperitoneal glucose tolerance test |
|
0 |
post glucose injection |
60 |
min |
|
|
|
11614 |
107 |
F344/NHsd |
plasma insulin level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood insulin amount |
female |
119 days
| 10 |
17.0 |
mU/l |
2.4 |
7.59 |
intraperitoneal glucose tolerance test |
|
0 |
post glucose injection |
60 |
min |
|
|
|
11615 |
107 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
313.2 |
mg/dl |
12.6 |
41.79 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11441 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
153.0 |
mg/dl |
5.4 |
17.91 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
60 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11436 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
297.0 |
mg/dl |
12.6 |
43.65 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
|
|
|
13092 |
330 |
F344.GK-(D1Rat175-D1Rat90)/Swe |
blood insulin level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood insulin amount |
male |
95 days
| 12 |
131.3 |
mU/l |
12.39 |
42.91 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
|
micrograms/L |
|
13095 |
330 |
F344.GK-(D1Rat175-D1Rat90)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
336.6 |
mg/dl |
10.8 |
37.41 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
|
|
|
13097 |
330 |
F344.GK-(D1Got250-D1Rat90)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
369.0 |
mg/dl |
9.0 |
31.18 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
|
|
|
13101 |
330 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65 days
| 11 |
0.03 |
mg/dl |
0.0 |
0.01 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
|
67626 |
85 |
F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 15 |
0.08 |
mg/dl |
0.01 |
0.05 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
|
67634 |
85 |
BN |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 20 |
129.8 |
mg/dl |
1.7 |
7.6 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
60 |
min |
|
|
|
68075 |
836 |
BN |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 20 |
138.7 |
mg/dl |
2.6 |
11.63 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
90 |
min |
|
|
|
68078 |
836 |
NTac:SD |
serum glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) (for 0.5 hours) |
Vaira S, et al., Endocrinology. 2012 Nov;153(11):5622-8. doi: 10.1210/en.2012-1462. Epub 2012 Sep 4. |
blood glucose amount |
not specified |
70 days
| 10 |
299.4 |
mg/dl |
6.69 |
21.16 |
intraperitoneal glucose tolerance test |
|
0.0 |
glucose inj |
60 |
min |
|
|
|
104541 |
2969 |
GK/Jpe |
blood glucose level |
fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) |
Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. |
blood glucose amount |
male |
540 days
| 20 |
332.5 |
mg/dl |
47.7 |
213.32 |
intraperitoneal glucose tolerance test |
|
0.0 |
|
120 |
min |
|
|
|
108010 |
3108 |
GK/Jpe |
blood glucose level |
controlled cholesterol content diet (1.25 %) (for 90 days) and controlled cocoa butter content diet (7.5 g/kg) (for 90 days) then soybean oil (2 ml/kg) then fasting (2 ml/kg) (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) |
Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. |
blood glucose amount |
male |
540 days
| 10 |
338.6 |
mg/dl |
23.4 |
74.0 |
intraperitoneal glucose tolerance test |
|
0.0 |
|
120 |
min |
|
|
|
108012 |
3108 |
Jcl:WI |
serum insulin level |
fasting then glucose solution (2 g/kg) (for 0.5 hours) |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood insulin amount |
male |
140 days
| 7 |
0.0 |
mg/dl |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
|
0.0 |
glucose |
30 |
min |
|
|
|
110217 |
3167 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65 days
| 11 |
0.01 |
mg/dl |
0.0 |
0.0 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
0 |
min |
|
|
|
67624 |
85 |
F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 15 |
0.01 |
mg/dl |
0.0 |
0.01 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
0 |
min |
|
|
|
67632 |
85 |
BN/Crl |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
female |
84 days
| 18 |
102.6 |
mg/dl |
3.6 |
15.27 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
|
0.8 g glucose/kg |
|
67321 |
66 |
F344.GK-(D1Swe4-D1Rat85)/Swe |
blood insulin level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood insulin amount |
male |
95 days
| 12 |
230.39 |
mU/l |
24.77 |
85.82 |
intraperitoneal glucose tolerance test |
tail vein |
0 |
post glucose injection |
15 |
min |
|
micrograms/L |
|
13113 |
330 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
309.6 |
mg/dl |
9.0 |
29.85 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11462 |
85 |
F344/NSlc |
blood glucose level |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 7 |
149.0 |
mg/dl |
3.52 |
9.31 |
oral glucose tolerance test |
|
0 |
oral dose |
120 |
min |
|
|
|
13160 |
106 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 15 |
135.0 |
mg/dl |
5.4 |
20.91 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
60 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11434 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
84.6 |
mg/dl |
1.8 |
5.97 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
0 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11449 |
85 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 15 |
88.2 |
mg/dl |
3.6 |
13.94 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
60 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11454 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
189.0 |
mg/dl |
7.2 |
23.88 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11459 |
85 |
BN/SsN |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
116.64 |
mg/dl |
1.5 |
22.32 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
120 |
min |
|
|
|
65981 |
114 |
N:HS |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
111.6 |
mg/dl |
0.49 |
7.2 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
0 |
min |
|
|
|
65944 |
114 |
BN/SsN |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
108.54 |
mg/dl |
1.02 |
15.12 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
0 |
min |
|
|
|
65945 |
114 |
SDT/Jcl |
blood glucose level area under curve (AUC) |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 5 |
8.3 |
(mg/dl) x min |
1.91 |
4.27 |
oral glucose tolerance test |
|
0.0 |
oral dose |
0 |
|
trapezoid rule used for calculation |
|
|
11604 |
106 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 15 |
109.8 |
mg/dl |
3.6 |
13.94 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11431 |
85 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
91.8 |
mg/dl |
1.8 |
5.97 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11456 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level area under curve (AUC) |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
13600.0 |
(mg/dl) x min |
327.27 |
1085.44 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11468 |
85 |
WOKW |
blood glucose level |
glucose solution (2 g/kg) |
Kloting I, et al., Biochem Biophys Res Commun 2001 Jun 1;284(1):150-6. |
blood glucose amount |
female |
0 days
| 12 |
91.0 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
|
0.0 |
intraperitoneal injection |
0 |
min |
glucose analyser (Medingen ESAT 6660-2, Germany) |
average of measures taken at 196 days, 210 days and 224 days |
|
13271 |
251 |
DA/K |
blood glucose level |
glucose solution (2 g/kg) |
Kloting I, et al., Biochem Biophys Res Commun 2001 Jun 1;284(1):150-6. |
blood glucose amount |
female |
0 days
| 12 |
105.0 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
|
0.0 |
intraperitoneal injection |
0 |
min |
glucose analyser (Medingen ESAT 6660-2, Germany) |
average of measures taken at 196 days, 210 days and 224 days |
|
13273 |
251 |
F344/NSlc |
blood glucose level |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 7 |
99.0 |
mg/dl |
4.48 |
11.85 |
oral glucose tolerance test |
|
0 |
oral dose |
0 |
min |
|
|
|
13156 |
106 |
SDT/Jcl |
blood glucose level |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 5 |
767.2 |
mg/dl |
17.6 |
39.35 |
oral glucose tolerance test |
|
0 |
oral dose |
30 |
min |
|
|
|
13166 |
106 |
BN.GK-(D8Got302-D8Got130)/Ox |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
male |
84 days
| 12 |
113.4 |
mg/dl |
5.4 |
18.71 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
|
0.8 g glucose/kg |
|
67317 |
66 |
BN/Crl |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
male |
168 days
| 20 |
88.2 |
mg/dl |
3.6 |
16.1 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma glucose analysis |
0.8 g glucose/kg |
|
67318 |
66 |
BN/Crl |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
male |
84 days
| 15 |
7.19 |
mU/l |
1.01 |
3.9 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67327 |
66 |
BN.GK-(D8Rat29-D8Got130)/Ox |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
male |
168 days
| 12 |
6.76 |
mU/l |
1.29 |
4.49 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67331 |
66 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level area under curve (AUC) |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
18200.0 |
(mg/dl) x min |
509.09 |
1688.46 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11448 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
129.6 |
mg/dl |
3.6 |
11.94 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11433 |
85 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
127.8 |
mg/dl |
3.6 |
11.94 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11432 |
85 |
F344.GK-(D1Got250-D1Rat90)/Swe |
blood insulin level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood insulin amount |
male |
95 days
| 12 |
185.8 |
mU/l |
19.82 |
68.65 |
intraperitoneal glucose tolerance test |
tail vein |
0 |
post glucose injection |
15 |
min |
|
micrograms/L |
|
13100 |
330 |
WBN/KobSlc |
blood glucose level |
controlled protein content diet (for 120 days) then fasting (for 9 hours) then glucose solution |
Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. |
blood glucose amount |
male |
120 days
| 5 |
266.7 |
mg/dl |
13.9 |
31.08 |
oral glucose tolerance test |
|
|
glucose challenge |
30 |
min |
glucose dose not specified |
serum glucose |
WBN/Kob rats were studied as a model of pancreatitis and diabetes mellitus |
12892 |
321 |
WBN/KobSlc |
blood glucose level |
controlled protein content diet (for 120 days) then fasting (for 9 hours) then glucose solution |
Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. |
blood glucose amount |
male |
120 days
| 5 |
313.5 |
mg/dl |
25.9 |
57.91 |
oral glucose tolerance test |
|
|
glucose challenge |
60 |
min |
glucose dose not specified |
serum glucose |
WBN/Kob rats were studied as a model of pancreatitis and diabetes mellitus |
12895 |
321 |
F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65 days
| 15 |
0.0 |
mg/dl |
0.0 |
0.0 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
0 |
min |
|
|
|
67623 |
85 |
F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 20 |
0.01 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
|
67658 |
85 |
N:HS |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
151.2 |
mg/dl |
2.31 |
34.2 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
30 |
min |
|
|
|
65972 |
114 |
F344/NRrrc |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
249.12 |
mg/dl |
5.16 |
76.5 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
30 |
min |
|
|
|
65977 |
114 |
BN/Seac |
blood glucose level area under curve (AUC) |
fasting (for 18 hours) then glucose solution (2 g/kg) |
Masuyama T, et al., Biochem Biophys Res Commun 2003 Apr 25;304(1):196-206. |
blood glucose amount |
male |
140 days
| 0 |
17646.0 |
(mg/dl) x min |
510.0 |
|
oral glucose tolerance test |
|
0.0 |
oral dose |
120 |
min |
|
|
|
67911 |
833 |
GK/MolTac |
blood glucose level |
sodium chloride solution (for 23 days) then fasting (for 16 hours) then glucose solution (2 g/kg) |
Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. |
blood glucose amount |
male |
95 days-102 days |
4 |
168.0 |
mg/dl |
9.0 |
18.0 |
oral glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
103805 |
2864 |
SD-Lepem1Sage-/- |
serum glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) (for 1 hours) |
Vaira S, et al., Endocrinology. 2012 Nov;153(11):5622-8. doi: 10.1210/en.2012-1462. Epub 2012 Sep 4. |
blood glucose amount |
not specified |
70 days
| 10 |
361.2 |
mg/dl |
35.67 |
112.8 |
intraperitoneal glucose tolerance test |
|
0.0 |
glucose inj |
60 |
min |
|
|
|
104544 |
2969 |
GK |
pancreatic islet insulin release measurement |
glucose solution (2.8 mmol/l) (for 1.5 hours) |
Ladriere L, et al., Cell Biochem Funct. 1997 Dec;15(4):287-92. doi: 10.1002/(SICI)1099-0844(199712)15:4<287::AID-CBF753>3.0.CO;2-X. |
pancreatic beta cell physiology trait |
male |
73 days
| 33 |
26.4 |
uU/islet/90min |
3.7 |
21.25 |
radioimmunoassay |
|
0.0 |
glucose |
90 |
min |
ex vivo incubation |
|
|
110627 |
3179 |
GK |
pancreatic islet insulin release measurement |
controlled dehydroepiandrosterone content diet (0.2 %) (for 28 days) then glucose solution (2.8 mmol/l) (for 1.5 hours) |
Ladriere L, et al., Cell Biochem Funct. 1997 Dec;15(4):287-92. doi: 10.1002/(SICI)1099-0844(199712)15:4<287::AID-CBF753>3.0.CO;2-X. |
pancreatic beta cell physiology trait |
female |
73 days
| 33 |
12.9 |
uU/islet/90min |
2.6 |
14.94 |
radioimmunoassay |
|
0.0 |
glucose |
90 |
min |
ex vivo incubation |
|
|
110630 |
3179 |
GK |
pancreatic islet insulin release measurement |
glucose solution (16.7 mmol/l) (for 1.5 hours) |
Ladriere L, et al., Cell Biochem Funct. 1997 Dec;15(4):287-92. doi: 10.1002/(SICI)1099-0844(199712)15:4<287::AID-CBF753>3.0.CO;2-X. |
pancreatic beta cell physiology trait |
male |
73 days
| 33 |
113.4 |
uU/islet/90min |
11.1 |
63.76 |
radioimmunoassay |
|
0.0 |
glucose |
90 |
min |
ex vivo incubation |
|
|
110631 |
3179 |
Jcl:WI |
serum insulin level |
vildagliptin (30 mg/kg/d) (for 92 days) then fasting then glucose solution (2 g/kg) (for 0.5 hours) |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood insulin amount |
male |
140 days
| 7 |
0.0 |
mg/dl |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
|
0.0 |
glucose |
30 |
min |
|
|
|
110218 |
3167 |
GK/Jpe |
blood glucose level |
controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) |
Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. |
blood glucose amount |
male |
540 days
| 7 |
418.68 |
mg/dl |
28.8 |
76.2 |
intraperitoneal glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
110867 |
3193 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65 days
| 11 |
0.07 |
mg/dl |
0.01 |
0.03 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
|
67627 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
333.0 |
mg/dl |
14.4 |
47.76 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11442 |
85 |
F344/DuCrlCrlj |
plasma glucose level |
fasting (for 16 hours) then glucose solution |
Hirashima T, et al., Diabetes Res Clin Pract 1995 Feb;27(2):91-6. |
blood glucose amount |
male |
210 days
| 7 |
128.0 |
mg/dl |
2.27 |
6.0 |
oral glucose tolerance test |
|
0.0 |
oral dose |
120 |
min |
|
|
|
67279 |
729 |
F344.GK-(D1Mgh14-D1Rat90)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
250.2 |
mg/dl |
10.8 |
37.41 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
|
|
|
13107 |
330 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 11 |
100.8 |
mg/dl |
5.4 |
17.91 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
0 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11429 |
85 |
WBN/KobSlc |
serum insulin level |
controlled protein content diet (for 120 days) then fasting (for 9 hours) then glucose solution |
Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. |
blood insulin amount |
male |
120 days
| 5 |
0.0 |
mg/dl |
0.0 |
0.0 |
oral glucose tolerance test |
|
|
glucose challenge |
30 |
min |
glucose dose not specified |
serum glucose |
|
12904 |
321 |
WKY/NHsd |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood glucose amount |
male |
119 days
| 10 |
98.1 |
mg/dl |
2.5 |
7.91 |
plasma glucose analysis |
|
0 |
|
0 |
|
|
|
|
13174 |
107 |
F344/NHsd |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood glucose amount |
male |
119 days
| 10 |
131.6 |
mg/dl |
3.0 |
9.49 |
intraperitoneal glucose tolerance test |
|
0 |
post glucose injection |
60 |
min |
|
|
|
13176 |
107 |
F344/NRrrc |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 7 |
185.5 |
mg/dl |
4.0 |
10.58 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
60 |
min |
|
|
|
68076 |
836 |
N:HS |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
124.2 |
mg/dl |
0.97 |
14.4 |
intraperitoneal glucose tolerance test |
|
0.0 |
glucose injection |
60 |
min |
|
|
|
65978 |
114 |
SD-Lepem1Sage-/- |
serum glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) (for 2 hours) |
Vaira S, et al., Endocrinology. 2012 Nov;153(11):5622-8. doi: 10.1210/en.2012-1462. Epub 2012 Sep 4. |
blood glucose amount |
not specified |
70 days
| 10 |
181.6 |
mg/dl |
18.45 |
58.34 |
intraperitoneal glucose tolerance test |
|
0.0 |
glucose inj |
60 |
min |
|
|
|
104546 |
2969 |
LETO |
plasma glucose level |
fasting (for 16 hours) then glucose solution |
Hirashima T, et al., Diabetes Res Clin Pract 1995 Feb;27(2):91-6. |
blood glucose amount |
male |
210 days
| 14 |
150.0 |
mg/dl |
1.87 |
7.0 |
oral glucose tolerance test |
|
0.0 |
oral dose |
120 |
min |
|
|
|
67278 |
729 |
BN.GK-(D8Got302-D8Got130)/Ox |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
female |
84 days
| 13 |
120.6 |
mg/dl |
5.4 |
19.47 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
|
0.8 g glucose/kg |
|
67323 |
66 |
BN/Crl |
plasma glucose level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood glucose amount |
female |
168 days
| 11 |
99.0 |
mg/dl |
5.4 |
17.91 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
|
0.8 g glucose/kg |
|
67324 |
66 |
F344/DuCrlCrlj |
blood glucose level area under curve (AUC) |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 15 |
15545.45 |
(mg/dl) x min |
381.82 |
1478.78 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11446 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
86.4 |
mg/dl |
3.6 |
11.94 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11453 |
85 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level area under curve (AUC) |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
14072.73 |
(mg/dl) x min |
363.64 |
1206.05 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11469 |
85 |
F344/NCrl |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
325.8 |
mg/dl |
10.8 |
37.41 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
|
|
|
13086 |
330 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
blood insulin level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood insulin amount |
male |
95 days
| 12 |
136.25 |
mU/l |
14.86 |
51.49 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
|
micrograms/L |
|
13089 |
330 |
F344.GK-(D1Swe4-D1Rat85)/Swe |
blood glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) |
Granhall C, et al., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1. |
blood glucose amount |
male |
95 days
| 12 |
306.0 |
mg/dl |
9.0 |
31.18 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
|
|
|
13114 |
330 |
SDT/Jcl |
blood glucose level |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 5 |
702.8 |
mg/dl |
25.39 |
56.77 |
oral glucose tolerance test |
|
0 |
oral dose |
60 |
min |
|
|
|
13167 |
106 |
WKY/NHsd |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood glucose amount |
female |
119 days
| 10 |
163.7 |
mg/dl |
7.2 |
22.77 |
intraperitoneal glucose tolerance test |
|
0 |
post glucose injection |
60 |
min |
|
|
|
13183 |
107 |
WKY/NHsd |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 |
blood glucose amount |
female |
119 days
| 10 |
84.3 |
mg/dl |
6.9 |
21.82 |
plasma glucose analysis |
|
0 |
|
0 |
|
|
|
|
13184 |
107 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65 days
| 11 |
0.02 |
mg/dl |
0.0 |
0.01 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
|
67629 |
85 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 11 |
0.01 |
mg/dl |
0.0 |
0.02 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
0 |
min |
|
|
|
67633 |
85 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 11 |
0.07 |
mg/dl |
0.02 |
0.06 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
|
67636 |
85 |
F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 15 |
0.07 |
mg/dl |
0.01 |
0.04 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
|
67637 |
85 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 20 |
90.0 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
0 |
min |
|
|
|
67647 |
85 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 20 |
118.8 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
60 |
min |
|
|
|
67650 |
85 |
F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 20 |
0.0 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
0 |
min |
|
|
|
67656 |
85 |
WKY/N |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
406.8 |
mg/dl |
4.67 |
69.3 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
30 |
min |
|
|
|
65976 |
114 |
N:HS |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
109.8 |
mg/dl |
0.07 |
1.08 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
120 |
min |
|
|
|
65979 |
114 |
WKY/N |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
221.4 |
mg/dl |
3.37 |
50.04 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
120 |
min |
|
|
|
65982 |
114 |
BN |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 20 |
91.3 |
mg/dl |
1.5 |
6.71 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
0 |
min |
|
|
|
68069 |
836 |
OLETF |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 14 |
402.4 |
mg/dl |
19.0 |
71.09 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
90 |
min |
|
|
|
68080 |
836 |
BN |
plasma glucose level |
fasting (for 16 hours) then glucose solution (2 g/kg) |
Kanemoto N, et al., Mamm Genome 1998 Jun;9(6):419-25 |
blood glucose amount |
male |
210 days
| 20 |
120.5 |
mg/dl |
2.6 |
11.63 |
oral glucose tolerance test |
|
0.0 |
oral glucose |
120 |
min |
|
|
|
68081 |
836 |
GK/MolTac |
blood glucose level |
rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 16 hours) then glucose solution (2 g/kg) |
Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. |
blood glucose amount |
male |
122 days-129 days |
4 |
145.0 |
mg/dl |
7.5 |
15.0 |
oral glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
103810 |
2864 |
NTac:SD |
serum glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) (for 1 hours) |
Vaira S, et al., Endocrinology. 2012 Nov;153(11):5622-8. doi: 10.1210/en.2012-1462. Epub 2012 Sep 4. |
blood glucose amount |
not specified |
70 days
| 10 |
213.9 |
mg/dl |
6.44 |
20.37 |
intraperitoneal glucose tolerance test |
|
0.0 |
glucose inj |
60 |
min |
|
|
|
104543 |
2969 |
GK/Jpe |
blood glucose level |
controlled cholesterol content diet (1.25 %) (for 90 days) and controlled cocoa butter content diet (7.5 %) (for 90 days) then fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) |
Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. |
blood glucose amount |
male |
540 days
| 10 |
419.1 |
mg/dl |
28.5 |
90.12 |
intraperitoneal glucose tolerance test |
|
0.0 |
|
120 |
min |
|
|
|
108011 |
3108 |
GK |
pancreatic islet insulin release measurement |
glucose solution (2.8 mmol/l) (for 1.5 hours) |
Ladriere L, et al., Cell Biochem Funct. 1997 Dec;15(4):287-92. doi: 10.1002/(SICI)1099-0844(199712)15:4<287::AID-CBF753>3.0.CO;2-X. |
pancreatic beta cell physiology trait |
female |
73 days
| 33 |
33.0 |
uU/islet/90min |
4.6 |
26.42 |
radioimmunoassay |
|
0.0 |
glucose |
90 |
min |
ex vivo incubation |
|
|
110629 |
3179 |
GK/Jpe |
blood glucose level |
controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) then fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) |
Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. |
blood glucose amount |
male |
540 days
| 7 |
363.6 |
mg/dl |
9.0 |
23.81 |
intraperitoneal glucose tolerance test |
|
0.0 |
|
0 |
|
|
|
|
110869 |
3193 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65 days
| 11 |
0.0 |
mg/dl |
0.0 |
0.0 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
0 |
min |
|
|
|
67622 |
85 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65 days
| 11 |
0.06 |
mg/dl |
0.01 |
0.03 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
|
67630 |
85 |
F344.GK-(D1Arb42a-D1Rat90)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 11 |
0.05 |
mg/dl |
0.01 |
0.04 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
|
67638 |
85 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 11 |
0.07 |
mg/dl |
0.02 |
0.06 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
|
67640 |
85 |
F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95 days
| 20 |
111.6 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
90 |
min |
|
|
|
67651 |
85 |
F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95 days
| 20 |
0.01 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
|
67657 |
85 |
BN.GK-(D8Got302-D8Got130)/Ox |
plasma insulin level |
fasting (between 16 and 18 hours) then glucose solution (0.8 g/kg) |
Wallis RH, et al., Diabetologia 2004 Jun;47(6):1096-106. Epub 2004 May 26 |
blood insulin amount |
female |
84 days
| 18 |
2.73 |
mU/l |
0.43 |
1.83 |
intravenous glucose tolerance test |
|
0.0 |
|
0 |
|
plasma insulin analysis |
|
|
67335 |
66 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65 days
| 11 |
86.4 |
mg/dl |
1.8 |
5.97 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
0 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
|
11452 |
85 |
WBN/KobSlc |
blood glucose level |
controlled protein content diet (for 120 days) then fasting (for 9 hours) then glucose solution |
Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. |
blood glucose amount |
male |
120 days
| 5 |
216.9 |
mg/dl |
8.6 |
19.23 |
oral glucose tolerance test |
|
|
glucose challenge |
120 |
min |
glucose dose not specified |
serum glucose |
WBN/Kob rats were studied as a model of pancreatitis and diabetes mellitus |
12896 |
321 |
SDT/Jcl |
blood glucose level |
specific pathogen-free condition then fasting (for 16 hours) then glucose solution (2 g/kg) |
Fuse M, et al., Physiol Genomics. 2008 Jul 8;. |
blood glucose amount |
male |
420 days
| 5 |
566.2 |
mg/dl |
26.69 |
59.68 |
oral glucose tolerance test |
|
0 |
oral dose |
0 |
min |
|
|
|
13162 |
106 |
BN/SsN |
blood glucose level |
glucose solution (2 g/kg) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
blood glucose amount |
both |
118 days-125 days |
220 |
156.42 |
mg/dl |
3.48 |
51.66 |
intraperitoneal glucose tolerance test |
|
0 |
glucose injection |
30 |
min |
|
|
|
65975 |
114 |
NTac:SD |
serum glucose level |
fasting (for 6 hours) then glucose solution (2 g/kg) (for 2 hours) |
Vaira S, et al., Endocrinology. 2012 Nov;153(11):5622-8. doi: 10.1210/en.2012-1462. Epub 2012 Sep 4. |
blood glucose amount |
not specified |
42 days
| 10 |
95.6 |
mg/dl |
6.1 |
19.29 |
intraperitoneal glucose tolerance test |
|
0.0 |
glucose inj |
60 |
min |
|
|
|
104539 |
2969 |