COP.DA-(D16Rat12-D16Rat90)/Mco |
plasma triglyceride level |
fasting (for 16 hours) |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
blood triglyceride amount |
not specified |
105 days
| 15 |
0.23 |
mmol/l |
0.03 |
0.12 |
spectrophotometry |
0.0 |
0 |
68561 |
933 |
Hsd:WI |
liver malondialdehyde level to liver weight ratio |
fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
liver malondialdehyde amount |
not specified |
0 days
| 10 |
0.37 |
nmol/g |
0.03 |
0.08 |
spectrophotometry |
0.0 |
0 |
85614 |
1618 |
Hsd:WI |
liver malondialdehyde level to liver weight ratio |
acetaminophen (500 mg/kg) (for 1 days) then fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
liver malondialdehyde amount |
not specified |
0 days
| 10 |
0.71 |
nmol/g |
0.05 |
0.15 |
spectrophotometry |
0.0 |
0 |
85616 |
1618 |
Hsd:WI |
serum malondialdehyde level |
acetaminophen (500 mg/kg) (for 1 days) then thymoquinone (15 mg/kg) (for 1 days) then fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
blood malondialdehyde amount |
not specified |
0 days
| 10 |
162.5 |
nmol/l |
12.43 |
39.3 |
spectrophotometry |
0.0 |
0 |
85613 |
1618 |
F344/NHsd |
serum alanine aminotransferase activity level |
fasting (between 12 and 15 hours) then acetaminophen (1.5 g/kg) (for 1 days) |
McGill MR, et al., Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23. |
blood alanine transaminase amount |
not specified |
56 days-84 days |
4 |
101.0 |
U/l |
7.0 |
14.0 |
spectrophotometry |
0.0 |
0 |
84756 |
1601 |
COP.DA-(D16Rat12-D16Rat90)/Mco |
plasma free fatty acids level |
fasting (for 16 hours) |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
blood free fatty acid amount |
not specified |
105 days
| 15 |
0.29 |
mmol/l |
0.03 |
0.12 |
spectrophotometry |
0.0 |
0 |
68567 |
933 |
Hsd:SD |
serum alanine aminotransferase activity level |
fasting (between 12 and 15 hours) then acetaminophen (2 g/kg) (for 1 days) |
McGill MR, et al., Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23. |
blood alanine transaminase amount |
not specified |
56 days-84 days |
4 |
31.0 |
U/l |
4.0 |
8.0 |
spectrophotometry |
0.0 |
0 |
84759 |
1601 |
Hsd:WI |
liver malondialdehyde level to liver weight ratio |
thymoquinone (15 mg/kg) (for 1 days) then fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
liver malondialdehyde amount |
not specified |
0 days
| 10 |
0.33 |
nmol/g |
0.02 |
0.07 |
spectrophotometry |
0.0 |
0 |
85615 |
1618 |
F344/NHsd |
serum alanine aminotransferase activity level |
fasting (between 12 and 15 hours) then vehicle control condition (for 1 days) |
McGill MR, et al., Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23. |
blood alanine transaminase amount |
not specified |
56 days-84 days |
4 |
35.0 |
U/l |
11.0 |
22.0 |
spectrophotometry |
0.0 |
0 |
84754 |
1601 |
Hsd:WI |
serum malondialdehyde level |
fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
blood malondialdehyde amount |
not specified |
0 days
| 10 |
133.1 |
nmol/l |
9.42 |
29.8 |
spectrophotometry |
0.0 |
0 |
85610 |
1618 |
Hsd:WI |
serum malondialdehyde level |
thymoquinone (15 mg/kg) (for 1 days) then fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
blood malondialdehyde amount |
not specified |
0 days
| 10 |
119.7 |
nmol/l |
8.41 |
26.6 |
spectrophotometry |
0.0 |
0 |
85611 |
1618 |
COP.DA-(D3Rat233-D3Mgh14)/Mco |
plasma triglyceride level |
fasting (for 16 hours) |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
blood triglyceride amount |
not specified |
105 days
| 20 |
0.34 |
mmol/l |
0.03 |
0.13 |
spectrophotometry |
0.0 |
0 |
68562 |
933 |
Hsd:WI |
serum malondialdehyde level |
acetaminophen (500 mg/kg) (for 1 days) then fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
blood malondialdehyde amount |
not specified |
0 days
| 10 |
253.4 |
nmol/l |
17.9 |
56.6 |
spectrophotometry |
0.0 |
0 |
85612 |
1618 |
Hsd:SD |
serum alanine aminotransferase activity level |
fasting (between 12 and 15 hours) then acetaminophen (1 g/kg) (for 1 days) |
McGill MR, et al., Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23. |
blood alanine transaminase amount |
not specified |
56 days-84 days |
4 |
41.0 |
U/l |
11.0 |
22.0 |
spectrophotometry |
0.0 |
0 |
84758 |
1601 |
COP/OlaHsd |
plasma free fatty acids level |
fasting (for 16 hours) |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
blood free fatty acid amount |
not specified |
105 days
| 20 |
0.23 |
mmol/l |
0.02 |
0.09 |
spectrophotometry |
0.0 |
0 |
68566 |
933 |
COP/OlaHsd |
plasma triglyceride level |
fasting (for 16 hours) |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
blood triglyceride amount |
not specified |
105 days
| 20 |
0.29 |
mmol/l |
0.02 |
0.1 |
spectrophotometry |
0.0 |
0 |
68560 |
933 |
COP.DA-(D3Rat233-D3Mgh14)/Mco |
plasma free fatty acids level |
fasting (for 16 hours) |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
blood free fatty acid amount |
not specified |
105 days
| 20 |
0.22 |
mmol/l |
0.02 |
0.09 |
spectrophotometry |
0.0 |
0 |
68568 |
933 |
Hsd:WI |
liver malondialdehyde level to liver weight ratio |
acetaminophen (500 mg/kg) (for 1 days) then thymoquinone (15 mg/kg) (for 1 days) then fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
liver malondialdehyde amount |
not specified |
0 days
| 10 |
0.45 |
nmol/g |
0.03 |
0.11 |
spectrophotometry |
0.0 |
0 |
85617 |
1618 |
F344/NHsd |
serum alanine aminotransferase activity level |
fasting (between 12 and 15 hours) then acetaminophen (1 g/kg) (for 1 days) |
McGill MR, et al., Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23. |
blood alanine transaminase amount |
not specified |
56 days-84 days |
4 |
39.0 |
U/l |
4.0 |
8.0 |
spectrophotometry |
0.0 |
0 |
84755 |
1601 |
Hsd:SD |
serum alanine aminotransferase activity level |
fasting (between 12 and 15 hours) then vehicle control condition (for 1 days) |
McGill MR, et al., Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23. |
blood alanine transaminase amount |
not specified |
56 days-84 days |
4 |
30.0 |
U/l |
1.0 |
2.0 |
spectrophotometry |
0.0 |
0 |
84757 |
1601 |