| Hsd:WI |
serum urea nitrogen level |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
blood urea nitrogen amount |
male |
119.0 days-126.0 days |
5 |
77.76 |
mg/dl |
3.18 |
7.11 |
liquid phase colorimetry |
0.0 |
|
76164 |
1545 |
| Hsd:WI |
serum lactate dehydrogenase activity level |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
blood lactate dehydrogenase amount |
male |
119.0 days-126.0 days |
5 |
1068.0 |
U/l |
313.23 |
700.4 |
liquid phase colorimetry |
0.0 |
|
76177 |
1545 |
| Hsd:WI |
kidney superoxide dismutase activity to total protein level ratio |
vehicle control condition (for 10 days) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney superoxide dismutase activity |
male |
days
| 6 |
13.53 |
U/mg |
0.8 |
1.97 |
liquid phase colorimetry |
0.0 |
|
76187 |
1544 |
| Hsd:WI |
serum urea nitrogen level |
vehicle control condition (for 10 days) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
blood urea nitrogen amount |
male |
days
| 6 |
69.64 |
mg/dl |
2.5 |
6.12 |
liquid phase colorimetry |
0.0 |
|
75976 |
1544 |
| Hsd:WI |
body weight |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
body mass |
male |
119.0 days-126.0 days |
5 |
388.0 |
g |
16.82 |
37.6 |
body weighing method |
0.0 |
|
76041 |
1545 |
| Hsd:WI |
left kidney wet weight |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
kidney mass |
male |
119.0 days-126.0 days |
5 |
1.19 |
g |
0.06 |
0.13 |
post excision weight measurement |
0.0 |
|
76075 |
1545 |
| Hsd:WI |
both kidneys wet weight |
vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney mass |
male |
days
| 6 |
1.2 |
g |
0.05 |
0.13 |
post excision weight measurement |
0.0 |
|
75957 |
1544 |
| Hsd:WI |
serum creatinine level |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
blood creatinine amount |
male |
119.0 days-126.0 days |
5 |
0.68 |
mg/dl |
0.05 |
0.11 |
liquid phase colorimetry |
0.0 |
|
76170 |
1545 |
| Hsd:WI |
right kidney wet weight |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
kidney mass |
male |
119.0 days-126.0 days |
5 |
1.21 |
g |
0.04 |
0.08 |
post excision weight measurement |
0.0 |
|
76070 |
1545 |
| Hsd:WI |
kidney lipid peroxide level |
vehicle control condition (for 10 days) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney lipid peroxide amount |
male |
days
| 6 |
0.75 |
nmol/mg |
0.02 |
0.04 |
liquid phase colorimetry |
0.0 |
|
76256 |
1544 |
| Hsd:WI |
kidney superoxide dismutase activity to total protein level ratio |
vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney superoxide dismutase activity |
male |
days
| 6 |
8.13 |
U/mg |
0.79 |
1.94 |
liquid phase colorimetry |
0.0 |
|
76188 |
1544 |
| Hsd:WI |
spleen wet weight |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
spleen mass |
male |
119.0 days-126.0 days |
5 |
0.71 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
76115 |
1545 |
| Hsd:WI |
serum triglyceride level |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
blood triglyceride amount |
male |
119.0 days-126.0 days |
5 |
156.94 |
mg/dl |
14.93 |
33.39 |
liquid phase colorimetry |
0.0 |
|
76135 |
1545 |
| Hsd:WI |
serum calcium level |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
blood calcium amount |
male |
119.0 days-126.0 days |
5 |
12.82 |
mg/dl |
0.24 |
0.53 |
liquid phase colorimetry |
0.0 |
|
76141 |
1545 |
| Hsd:WI |
serum albumin level |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
blood albumin amount |
male |
119.0 days-126.0 days |
5 |
0.04 |
g/dl |
0.0 |
0.0 |
liquid phase colorimetry |
0.0 |
|
76149 |
1545 |
| Hsd:WI |
kidney catalase activity to total protein level ratio |
vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
catalase activity |
male |
days
| 6 |
21.73 |
nmol/mg |
0.62 |
1.51 |
liquid phase colorimetry |
0.0 |
|
76235 |
1544 |
| Hsd:WI |
liver wet weight |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
liver mass |
male |
119.0 days-126.0 days |
5 |
13.6 |
g |
1.05 |
2.34 |
post excision weight measurement |
0.0 |
|
76090 |
1545 |
| Hsd:WI |
timed urine volume |
vehicle control condition (for 10 days) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
urine output |
male |
days
| 6 |
6.8 |
ml/d |
0.61 |
1.5 |
urine volume measurement method |
0.0 |
|
75965 |
1544 |
| Hsd:WI |
body weight |
vehicle control condition (for 10 days) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
body mass |
male |
days
| 6 |
140.6 |
g |
0.53 |
1.3 |
body weighing method |
0.0 |
|
75951 |
1544 |
| Hsd:WI |
body weight |
vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
body mass |
male |
days
| 6 |
137.6 |
g |
0.45 |
1.1 |
body weighing method |
0.0 |
|
75952 |
1544 |
| Hsd:WI |
serum creatinine level |
vehicle control condition (for 10 days) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
blood creatinine amount |
male |
days
| 6 |
0.54 |
mg/dl |
0.01 |
0.03 |
serum creatinine analysis |
0.0 |
|
75972 |
1544 |
| Hsd:WI |
serum urea nitrogen level |
vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
blood urea nitrogen amount |
male |
days
| 6 |
96.11 |
mg/dl |
1.91 |
4.69 |
liquid phase colorimetry |
0.0 |
|
75977 |
1544 |
| Hsd:WI |
change in body weight to body weight ratio |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
body mass |
male |
119.0 days-126.0 days |
5 |
255.0 |
% |
13.42 |
30.0 |
body weighing method |
0.0 |
|
76065 |
1545 |
| Hsd:WI |
kidney glutathione peroxidase activity to total protein level ratio |
vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney glutathione peroxidase activity |
male |
days
| 6 |
7.54 |
U/mg |
0.51 |
1.24 |
liquid phase colorimetry |
0.0 |
|
76192 |
1544 |
| Hsd:WI |
kidney glutathione peroxidase activity to total protein level ratio |
vehicle control condition (for 10 days) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney glutathione peroxidase activity |
male |
days
| 6 |
22.63 |
U/mg |
1.35 |
3.3 |
liquid phase colorimetry |
0.0 |
|
76191 |
1544 |
| Hsd:WI |
serum total bilirubin level |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
blood bilirubin amount |
male |
119.0 days-126.0 days |
5 |
0.96 |
mg/dl |
0.07 |
0.17 |
liquid phase colorimetry |
0.0 |
|
76156 |
1545 |
| Hsd:WI |
kidney catalase activity to total protein level ratio |
vehicle control condition (for 10 days) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
catalase activity |
male |
days
| 6 |
35.98 |
nmol/mg |
0.81 |
1.98 |
liquid phase colorimetry |
0.0 |
|
76234 |
1544 |
| Hsd:WI |
kidney glutathione level |
vehicle control condition (for 10 days) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney glutathione amount |
male |
days
| 6 |
12385.0 |
ug/g |
257.2 |
630.01 |
liquid phase colorimetry |
0.0 |
|
76238 |
1544 |
| Hsd:WI |
kidney glutathione level |
vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney glutathione amount |
male |
days
| 6 |
7882.76 |
ug/g |
178.16 |
436.39 |
liquid phase colorimetry |
0.0 |
|
76239 |
1544 |
| Hsd:WI |
left kidney wet weight to body weight ratio |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
kidney mass |
male |
119.0 days-126.0 days |
5 |
3.07 |
mg/g |
0.07 |
0.16 |
post excision weight measurement |
0.0 |
|
76085 |
1545 |
| Hsd:WI |
liver weight to body weight ratio |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
liver mass |
male |
119.0 days-126.0 days |
5 |
34.85 |
g/kg |
1.21 |
2.7 |
post excision weight measurement |
0.0 |
|
76095 |
1545 |
| Hsd:WI |
serum total protein level |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
blood total protein amount |
male |
119.0 days-126.0 days |
5 |
9.38 |
g/dl |
0.67 |
1.5 |
liquid phase colorimetry |
0.0 |
|
76125 |
1545 |
| Hsd:WI |
serum total cholesterol level |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
blood cholesterol amount |
male |
119.0 days-126.0 days |
5 |
68.12 |
mg/dl |
6.42 |
14.36 |
liquid phase colorimetry |
0.0 |
|
76130 |
1545 |
| Hsd:WI |
kidney lipid peroxide level |
vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney lipid peroxide amount |
male |
days
| 6 |
1.51 |
nmol/mg |
0.03 |
0.08 |
liquid phase colorimetry |
0.0 |
|
76257 |
1544 |
| Hsd:WI |
spleen weight to body weight ratio |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
spleen mass |
male |
119.0 days-126.0 days |
5 |
0.18 |
% |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
76120 |
1545 |
| Hsd:WI |
both kidneys wet weight |
vehicle control condition (for 10 days) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney mass |
male |
days
| 6 |
0.82 |
g |
0.02 |
0.06 |
post excision weight measurement |
0.0 |
|
75956 |
1544 |
| Hsd:WI |
right kidney wet weight to body weight ratio |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
kidney mass |
male |
119.0 days-126.0 days |
5 |
3.14 |
mg/g |
0.06 |
0.13 |
post excision weight measurement |
0.0 |
|
76080 |
1545 |
| Hsd:WI |
timed urine volume |
vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
urine output |
male |
days
| 6 |
21.8 |
ml/d |
1.31 |
3.2 |
urine volume measurement method |
0.0 |
|
75966 |
1544 |
| Hsd:WI |
serum creatinine level |
vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
blood creatinine amount |
male |
days
| 6 |
1.69 |
mg/dl |
0.06 |
0.14 |
serum creatinine analysis |
0.0 |
|
75973 |
1544 |