| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
84 days
| 7 |
3.98 |
mm |
0.45 |
1.19 |
echocardiography |
0.0 |
|
0 |
|
99786 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
252 days
| 7 |
4.67 |
mm |
0.74 |
1.96 |
echocardiography |
0.0 |
|
0 |
|
99790 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
252 days
| 7 |
3.41 |
mm |
0.5 |
1.32 |
echocardiography |
0.0 |
|
0 |
|
99796 |
2319 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
168 days
| 7 |
80.2 |
% |
3.4 |
9.0 |
echocardiography |
0.0 |
|
0 |
|
99800 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle posterior wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle posterior wall thickness |
female |
91 days
| 8 |
2.06 |
mm |
0.04 |
0.11 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101713 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle fractional shortening |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 9 |
39.8 |
% |
2.5 |
7.5 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101719 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle fractional shortening |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 8 |
47.7 |
% |
1.9 |
5.37 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101721 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
E wave deceleration time |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 8 |
56.9 |
ms |
1.8 |
5.09 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101733 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
heart isovolumetric relaxation time |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart muscle relaxation trait |
female |
91 days
| 9 |
24.8 |
ms |
1.8 |
5.4 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101735 |
2622 |
| WKY |
heart posterior wall thickness |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle posterior wall thickness |
male |
238 days-252 days |
30 |
0.18 |
cm |
0.0 |
0.02 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
100347 |
2460 |
| SS.ZUC-Leprfa-/-/Slc |
ejection fraction |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
cardiac output trait |
male |
91 days
| 13 |
82.5 |
% |
1.94 |
6.99 |
echocardiography |
0.0 |
|
0 |
|
102010 |
2644 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
168 days
| 7 |
3.24 |
mm |
0.21 |
0.56 |
echocardiography |
0.0 |
|
0 |
|
99782 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 7 |
8.68 |
mm |
0.33 |
0.87 |
echocardiography |
0.0 |
|
0 |
|
99770 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
168 days
| 7 |
1.67 |
g |
0.06 |
0.16 |
echocardiography |
0.0 |
|
0 |
|
99812 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart ventricle septal wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 9 |
0.16 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101707 |
2622 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
168 days
| 7 |
1.89 |
mm |
0.16 |
0.42 |
echocardiography |
0.0 |
|
0 |
|
99776 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
84 days
| 7 |
3.19 |
mm |
0.2 |
0.53 |
echocardiography |
0.0 |
|
0 |
|
99780 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart ventricle septal wall thickness |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle wall thickness |
male |
91 days
| 13 |
0.21 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
|
0 |
|
101992 |
2644 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
84 days
| 7 |
7.52 |
mm |
0.32 |
0.85 |
echocardiography |
0.0 |
|
0 |
|
99768 |
2319 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
252 days
| 7 |
77.4 |
% |
6.0 |
15.87 |
echocardiography |
0.0 |
|
0 |
|
99802 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle relative wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 9 |
44.0 |
% |
2.0 |
6.0 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101727 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
myocardial performance index |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 9 |
0.44 |
null |
0.01 |
0.03 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101739 |
2622 |
| SS-Nppbem2Mcwi-/- |
heart rate |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
168 days
| 7 |
349.0 |
beats/min |
20.0 |
52.92 |
echocardiography |
0.0 |
|
0 |
|
99818 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart posterior wall thickness |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle posterior wall thickness |
male |
91 days
| 13 |
0.21 |
cm |
0.01 |
0.02 |
echocardiography |
0.0 |
|
0 |
|
101998 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
time constant of left ventricular pressure decay |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricular blood pressure trait |
male |
91 days
| 13 |
33.52 |
ms |
1.09 |
3.93 |
echocardiography |
0.0 |
|
0 |
|
102019 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
E wave deceleration time |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
blood flow trait |
male |
91 days
| 13 |
53.05 |
ms |
1.48 |
5.34 |
echocardiography |
0.0 |
|
0 |
|
102013 |
2644 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
84 days
| 7 |
3.29 |
mm |
0.19 |
0.5 |
echocardiography |
0.0 |
|
0 |
|
99792 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
252 days
| 7 |
41.6 |
% |
5.6 |
14.82 |
echocardiography |
0.0 |
|
0 |
|
99808 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-diastolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
168 days
| 7 |
1.92 |
mm |
0.12 |
0.32 |
echocardiography |
0.0 |
|
0 |
|
99764 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart ventricle septal wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 8 |
0.21 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101709 |
2622 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
84 days
| 7 |
2.03 |
mm |
0.06 |
0.16 |
echocardiography |
0.0 |
|
0 |
|
99774 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 7 |
44.3 |
% |
2.8 |
7.41 |
echocardiography |
0.0 |
|
0 |
|
99806 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
252 days
| 7 |
1.78 |
g |
0.04 |
0.11 |
echocardiography |
0.0 |
|
0 |
|
99814 |
2319 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
84 days
| 7 |
83.3 |
% |
4.3 |
11.38 |
echocardiography |
0.0 |
|
0 |
|
99798 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle end-diastolic diameter |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 9 |
7.21 |
mm |
0.21 |
0.63 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101715 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle end-diastolic diameter |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 8 |
7.2 |
mm |
0.14 |
0.4 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101717 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
E wave deceleration time |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 9 |
35.4 |
ms |
1.2 |
3.6 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101731 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle fractional shortening |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 13 |
47.66 |
% |
2.43 |
8.76 |
echocardiography |
0.0 |
|
0 |
|
102007 |
2644 |
| WKY |
E/A wave ratio |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
blood flow trait |
male |
238 days-252 days |
30 |
1.85 |
null |
0.14 |
0.77 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
100356 |
2460 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
84 days
| 7 |
47.3 |
% |
4.1 |
10.85 |
echocardiography |
0.0 |
|
0 |
|
99804 |
2319 |
| WKY |
heart left ventricle end-diastolic diameter |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
238 days-252 days |
30 |
10.6 |
mm |
0.1 |
0.55 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
100341 |
2460 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
252 days
| 7 |
3.48 |
mm |
0.26 |
0.69 |
echocardiography |
0.0 |
|
0 |
|
99784 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
168 days
| 7 |
4.83 |
mm |
0.35 |
0.93 |
echocardiography |
0.0 |
|
0 |
|
99788 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
calculated heart left ventricle weight |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle mass |
female |
91 days
| 8 |
1114.0 |
mg |
35.0 |
98.99 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101725 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart isovolumetric relaxation time |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart muscle relaxation trait |
female |
91 days
| 8 |
43.1 |
ms |
1.5 |
4.24 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101737 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
time constant of left ventricular pressure decay |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 8 |
47.3 |
ms |
1.5 |
4.24 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101749 |
2622 |
| WKY |
heart left ventricle end-systolic diameter |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-systolic diameter |
male |
238 days-252 days |
30 |
8.9 |
mm |
0.2 |
1.1 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
100344 |
2460 |
| WKY |
heart left ventricle fractional shortening |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
238 days-252 days |
30 |
15.8 |
% |
0.7 |
3.83 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
100350 |
2460 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
252 days
| 7 |
2.17 |
mm |
1.94 |
5.13 |
echocardiography |
0.0 |
|
0 |
|
99778 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle end-diastolic diameter |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 13 |
8.27 |
mm |
0.13 |
0.47 |
echocardiography |
0.0 |
|
0 |
|
101995 |
2644 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-diastolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
252 days
| 7 |
2.26 |
mm |
0.23 |
0.61 |
echocardiography |
0.0 |
|
0 |
|
99766 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-diastolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
84 days
| 7 |
2.01 |
mm |
0.08 |
0.21 |
echocardiography |
0.0 |
|
0 |
|
99762 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
252 days
| 7 |
7.99 |
mm |
0.62 |
1.64 |
echocardiography |
0.0 |
|
0 |
|
99772 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
168 days
| 7 |
3.17 |
mm |
0.17 |
0.45 |
echocardiography |
0.0 |
|
0 |
|
99794 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle posterior wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle posterior wall thickness |
female |
91 days
| 9 |
1.5 |
mm |
0.02 |
0.06 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101711 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
calculated heart left ventricle weight |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle mass |
female |
91 days
| 9 |
764.0 |
mg |
27.0 |
81.0 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101723 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle relative wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 8 |
57.0 |
% |
2.0 |
5.66 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101729 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
myocardial performance index |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 8 |
0.61 |
null |
0.03 |
0.08 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101741 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
time constant of left ventricular pressure decay |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 9 |
36.2 |
ms |
0.5 |
1.5 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101747 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 8 |
0.63 |
mmHg/mm |
0.05 |
0.14 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101753 |
2622 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
84 days
| 7 |
1.53 |
g |
0.08 |
0.21 |
echocardiography |
0.0 |
|
0 |
|
99810 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart rate |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
84 days
| 7 |
382.0 |
beats/min |
45.0 |
119.06 |
echocardiography |
0.0 |
|
0 |
|
99816 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle relative wall thickness |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle wall thickness |
male |
91 days
| 13 |
49.0 |
% |
1.0 |
3.61 |
echocardiography |
0.0 |
|
0 |
|
102004 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
heart isovolumetric relaxation time |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart muscle relaxation trait |
male |
91 days
| 13 |
40.75 |
ms |
2.42 |
8.73 |
echocardiography |
0.0 |
|
0 |
|
102016 |
2644 |
| WKY |
ejection fraction |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
cardiac output trait |
male |
238 days-252 days |
30 |
37.0 |
% |
1.4 |
7.67 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
100353 |
2460 |
| SS-Nppbem2Mcwi-/- |
heart rate |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
252 days
| 7 |
327.0 |
beats/min |
19.0 |
50.27 |
echocardiography |
0.0 |
|
0 |
|
99820 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 9 |
0.32 |
mmHg/mm |
0.02 |
0.06 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
101751 |
2622 |
| WKY |
heart ventricle septal wall thickness |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle wall thickness |
male |
238 days-252 days |
30 |
0.1 |
cm |
0.0 |
0.02 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
100338 |
2460 |
