Phenominer Database Results (6 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
F344.BN-(D16Mit5-D16Rat75) serum estradiol level orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) and 17 beta-estradiol (10 mg/kg) (for 35 days) De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. blood estradiol amount male 0 days 5 25.7 pg/ml 2.33 5.2 immunoassay 0.0 N-nitrosodiethylamine injection at 200mg/kg 56 days intraperitoneal 67444 655
F344.BN-(D16Mit5-D16Rat75) liver tumorous lesion number to liver volume ratio orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. liver integrity trait male 0 days 0 16820.0 /cm3 5100.0 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethylamine injection at 200mg/kg 56 days intraperitoneal Add 67445 655
F344.BN-(D16Mit5-D16Rat75) volume of liver occupied by tumorous lesions orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. liver integrity trait male 0 days 0 0.18 cm3 x 10000 0.11 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethylamine injection at 200mg/kg 56 days intraperitoneal 67793 655
F344.BN-(D16Mit5-D16Rat75) ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. liver integrity trait male 0 days 0 3.55 % 0.98 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethylamine injection at 200mg/kg 56 days intraperitoneal pcna index 68107 655
F344.BN-(D16Mit5-D16Rat75) serum testosterone level orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. blood testosterone amount male 0 days 5 0.85 ng/ml 0.03 0.07 immunoassay 0.0 N-nitrosodiethylamine injection at 200mg/kg 56 days intraperitoneal 67443 655
F344.BN-(D16Mit5-D16Rat75) volume of liver occupied by tumorous lesions as percentage of total liver volume orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. liver integrity trait male 0 days 0 19.0 % 5.4 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethylamine injection at 200mg/kg 56 days intraperitoneal 67446 655